Tetracycline Hydrochloride

Product NDC: 71335-2141
11-digit product format: 713352141
Labeler code: 71335
Product ID: 71335-2141_dbd18052-a245-4b01-8654-0505c06cfb26
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: Tetracycline Hydrochloride
Dosage form: CAPSULE
Route: ORAL
Labeler: Bryant Ranch Prepack
Application: ANDA210662
Marketing category: ANDA
Marketing start: 2019-01-18
Substance: TETRACYCLINE HYDROCHLORIDE
Active strength: 500 mg/1
Pharmacologic classes: Tetracycline-class Antimicrobial [EPC], Tetracyclines [CS]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
A210662-001	TETRACYCLINE HYDROCHLORIDE	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB		2018-11-07
A210662-002	TETRACYCLINE HYDROCHLORIDE	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB		2018-11-07

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-product	TE code
A210662-001	AB
A210662-002	AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	Approval date	Source SHA-256
2026-08-18 06:07:40	2026-07	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	A210662-001	TETRACYCLINE HYDROCHLORIDE	250MG	CAPSULE / ORAL	AB	2018-11-07	`bb7c543d1eb4…`
2022-03-09 01:35 UTC	2022-03	A210662-002	TETRACYCLINE HYDROCHLORIDE	500MG	CAPSULE / ORAL	AB	2018-11-07	`bb7c543d1eb4…`

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-08-18 06:07:40	2026-07	A210662-001	AB	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A210662-002	AB	1	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	A210662-001	AB	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A210662-002	AB	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A210662-001	AB	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A210662-002	AB	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A210662-001	AB	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A210662-002	AB	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A210662-001	AB	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A210662-002	AB	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A210662-001	AB	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A210662-002	AB	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A210662-001	AB	1	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A210662-002	AB	1	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A210662-001	AB	1	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A210662-002	AB	1	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A210662-001	AB	1	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A210662-002	AB	1	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A210662-001	AB	1	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A210662-002	AB	1	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A210662-001	AB	1	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A210662-002	AB	1	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A210662-001	AB	1	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A210662-002	AB	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A210662-001	AB	1	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A210662-002	AB	1	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A210662-001	AB	1	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A210662-002	AB	1	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	A210662-001	AB	1	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	A210662-002	AB	1	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A210662-001	AB	1	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A210662-002	AB	1	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	A210662-001	AB	1	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	A210662-002	AB	1	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	A210662-001	AB	1	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	A210662-002	AB	1	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	A210662-001	AB	1	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	A210662-002	AB	1	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	A210662-001	AB	1	`bb7c543d1eb4…`
2022-03-09 01:35 UTC	2022-03	A210662-002	AB	1	`bb7c543d1eb4…`

Additional Listing Data#

Finished product: Yes
Brand name base: Tetracycline Hydrochloride
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
TETRACYCLINE HYDROCHLORIDE	500 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
P6R62377KV	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
198252	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
2c9208db-5f4f-4382-854f-6786b1e458db	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
0be8e4ae-4d57-49f3-b3a9-e4728b4e8d15	Product name	1	20240313
6c13b22c-b3ba-4127-b768-0132dd5ab0d1	Product name	1	20230829
151122cd-8b80-4972-8b02-3a4dda642fbc	Product name	2	20200701
dea2eded-d1e7-46bb-9a3d-f8dc20de6277	Product name	1	20190408

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
71335-2141-1	Tetracycline Hydrochloride	60 in 1 BOTTLE, PLASTIC	CAPSULE	60	103
71335-2141-2	Tetracycline Hydrochloride	40 in 1 BOTTLE, PLASTIC	CAPSULE	40	103
71335-2141-3	Tetracycline Hydrochloride	30 in 1 BOTTLE, PLASTIC	CAPSULE	30	103
71335-2141-4	Tetracycline Hydrochloride	56 in 1 BOTTLE, PLASTIC	CAPSULE	56	103
71335-2141-5	Tetracycline Hydrochloride	28 in 1 BOTTLE, PLASTIC	CAPSULE	28	103
71335-2141-6	Tetracycline Hydrochloride	20 in 1 BOTTLE, PLASTIC	CAPSULE	20	103
71335-2141-7	Tetracycline Hydrochloride	90 in 1 BOTTLE, PLASTIC	CAPSULE	90	103
71335-2141-8	Tetracycline Hydrochloride	45 in 1 BOTTLE, PLASTIC	CAPSULE	45	103

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
71335-2141	TETRACYCLINE HYDROCHLORIDE CAPSULE [BRYANT RANCH PREPACK]	103	Current NDC, Legacy NDC, 8 package rows	20240420_2c9208db-5f4f-4382-854f-6786b1e458db.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Tetracycline Hydrochloride	TETRACYCLINE HYDROCHLORIDE	Breckenridge Pharmaceutical, Inc.	00acf413-c5d2-4a54-9d0d-56266cbc9edc	2026-05-22	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 210662 application number: ANDA210662
Tetracycline Hydrochloride	TETRACYCLINE HYDROCHLORIDE	Bryant Ranch Prepack	58e4b5b3-e093-46e7-b28e-a2c4821c5b63	2024-11-12	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 210662 application number: ANDA210662
Tetracycline Hydrochloride	TETRACYCLINE HYDROCHLORIDE	Bryant Ranch Prepack	2c9208db-5f4f-4382-854f-6786b1e458db	2024-04-03	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 210662 application number: ANDA210662 ndc (product): 71335-2141

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
P6R62377KV	TETRACYCLINE HYDROCHLORIDE	64-75-5	TETRACYCLINE HYDROCHLORIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
198252	tetracycline HCl 500 MG Oral Capsule	PSN	2c9208db-5f4f-4382-854f-6786b1e458db	103
198252	tetracycline hydrochloride 500 MG Oral Capsule	SCD	2c9208db-5f4f-4382-854f-6786b1e458db	103
198252	tetracycline (as tetracycline hydrochloride) 500 MG Oral Capsule	SY	2c9208db-5f4f-4382-854f-6786b1e458db	103
198252	tetracycline HCl 500 MG Oral Capsule	SY	2c9208db-5f4f-4382-854f-6786b1e458db	103

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
71335-2141-1	71335214101	60 CAPSULE in 1 BOTTLE, PLASTIC (71335-2141-1)	60 capsule	2024-04-03	0000-00-00	No	No	Current
71335-2141-2	71335214102	40 CAPSULE in 1 BOTTLE, PLASTIC (71335-2141-2)	40 capsule	2024-04-03	0000-00-00	No	No	Current
71335-2141-3	71335214103	30 CAPSULE in 1 BOTTLE, PLASTIC (71335-2141-3)	30 capsule	2022-07-29	0000-00-00	No	No	Current
71335-2141-4	71335214104	56 CAPSULE in 1 BOTTLE, PLASTIC (71335-2141-4)	56 capsule	2024-04-03	0000-00-00	No	No	Current
71335-2141-5	71335214105	28 CAPSULE in 1 BOTTLE, PLASTIC (71335-2141-5)	28 capsule	2024-04-03	0000-00-00	No	No	Current
71335-2141-6	71335214106	20 CAPSULE in 1 BOTTLE, PLASTIC (71335-2141-6)	20 capsule	2024-04-03	0000-00-00	No	No	Current
71335-2141-7	71335214107	90 CAPSULE in 1 BOTTLE, PLASTIC (71335-2141-7)	90 capsule	2024-04-03	0000-00-00	No	No	Current
71335-2141-8	71335214108	45 CAPSULE in 1 BOTTLE, PLASTIC (71335-2141-8)	45 capsule	2024-04-03	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Tetracycline Hydrochloride Capsules, USP.	Bryant Ranch Prepack	2024-04-03	HUMAN PRESCRIPTION DRUG LABEL	103