Eplerenone

Product NDC
71335-2355
11-digit product format
713352355
Labeler code
71335
Product ID
71335-2355_3b033db4-feaa-4c28-876e-8042b0f2cf60
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Eplerenone
Dosage form
TABLET, COATED
Route
ORAL
Labeler
Bryant Ranch Prepack
Application
ANDA207842
Marketing category
ANDA
Marketing start
2021-11-08
Substance
EPLERENONE
Active strength
25 mg/1
Pharmacologic classes
Aldosterone Antagonist [EPC], Aldosterone Antagonists [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A207842-001EPLERENONEEPLERENONE25MGTABLET / ORALAB2021-10-25
A207842-002EPLERENONEEPLERENONE50MGTABLET / ORALAB2021-10-25

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A207842-001AB
A207842-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 68 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-25caaa826d4ba7…
2026-08-18 06:07:402026-07A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-25caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-2503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-252680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-255bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-25d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-25d06236e962d9…
2024-10-29 15:01 UTC2024-10A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-2579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-25301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-251e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-258072bd15b7f6…
2024-05-31 18:47 UTC2024-05A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-258072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-255c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-255c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-255d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-255d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-254b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-254b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-25bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-25bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A207842-001EPLERENONE25MGTABLET / ORALAB2021-10-25782e0a99824c…
2021-12-28 21:50 UTC2021-12A207842-002EPLERENONE50MGTABLET / ORALAB2021-10-25782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 68 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A207842-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07A207842-002AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A207842-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A207842-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207842-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207842-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A207842-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A207842-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207842-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207842-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207842-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207842-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207842-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207842-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207842-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207842-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207842-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207842-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207842-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207842-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A207842-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A207842-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207842-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207842-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207842-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207842-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A207842-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A207842-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A207842-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A207842-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A207842-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A207842-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A207842-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A207842-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A207842-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A207842-002AB14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A207842-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A207842-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A207842-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12A207842-002AB1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
Eplerenone
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
EPLERENONE25 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
6995V82D0BInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
351256Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2002cf90-2d4a-43b1-bcd6-c447cbc7010fAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
6c046e2c-42d6-3179-f149-f207119f6ad5Product name620240530

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
71335-2355-1Eplerenone90 in 1 BOTTLE, PLASTICTABLET, COATED901
71335-2355-2Eplerenone30 in 1 BOTTLE, PLASTICTABLET, COATED301

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
71335-2355EPLERENONE TABLET, COATED [BRYANT RANCH PREPACK]1Current NDC, 2 package rows20240529_2002cf90-2d4a-43b1-bcd6-c447cbc7010f.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
EplerenoneEPLERENONEAvKAREd953457e-0aff-6c38-e053-2995a90a7d322026-01-14Warnings, Adverse reactionsExact identifier
application applno (ANDA): 207842
application number: ANDA207842
EplerenoneEPLERENONEBryant Ranch Prepack2002cf90-2d4a-43b1-bcd6-c447cbc7010f2024-05-28Warnings, Adverse reactionsExact identifier
application applno (ANDA): 207842
application number: ANDA207842
ndc (product): 71335-2355
EplerenoneEPLERENONEProficient Rx LP49b9759a-c1b9-4ebe-874b-81fb82a427552022-03-01Warnings, Adverse reactionsExact identifier
application applno (ANDA): 207842
application number: ANDA207842
EplerenoneEPLERENONEWestminster Pharmaceuticals, LLC316d3a98-4cd1-4499-a34c-cac87e0169442021-11-15Warnings, Adverse reactionsExact identifier
application applno (ANDA): 207842
application number: ANDA207842

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
351256eplerenone 25 MG Oral TabletPSN2002cf90-2d4a-43b1-bcd6-c447cbc7010f1
351256eplerenone 25 MG Oral TabletSCD2002cf90-2d4a-43b1-bcd6-c447cbc7010f1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
71335-2355-17133523550190 TABLET, COATED in 1 BOTTLE, PLASTIC (71335-2355-1) 2024-05-28NoNoCurrent
71335-2355-27133523550230 TABLET, COATED in 1 BOTTLE, PLASTIC (71335-2355-2) 2024-05-28NoNoCurrent