Hydromorphone Hydrochloride

Product NDC
71335-9701
11-digit product format
713359701
Labeler code
71335
Product ID
71335-9701_b9b96266-fe94-4282-915f-277433e1ca26
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Hydromorphone Hydrochloride
Dosage form
TABLET
Route
ORAL
Labeler
Bryant Ranch Prepack
Application
NDA019892
Marketing category
NDA AUTHORIZED GENERIC
Marketing start
2009-11-23
Substance
HYDROMORPHONE HYDROCHLORIDE
Active strength
4 mg/1
Pharmacologic classes
Full Opioid Agonists [MoA], Opioid Agonist [EPC]
DEA schedule
CII
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N019892-001DILAUDIDHYDROMORPHONE HYDROCHLORIDE8MGTABLET / ORALABRLD, RS1992-12-07
N019892-002DILAUDIDHYDROMORPHONE HYDROCHLORIDE4MGTABLET / ORALABRLD2007-11-09
N019892-003DILAUDIDHYDROMORPHONE HYDROCHLORIDE2MGTABLET / ORALABRLD2007-11-09

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
N019892-001AB
N019892-002AB
N019892-003AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N019892-001DILAUDID8MGTABLET / ORALABRLD, RS1992-12-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019892-002DILAUDID4MGTABLET / ORALABRLD2007-11-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019892-003DILAUDID2MGTABLET / ORALABRLD2007-11-09011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019892-001DILAUDID8MGTABLET / ORALABRLD, RS1992-12-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019892-002DILAUDID4MGTABLET / ORALABRLD2007-11-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019892-003DILAUDID2MGTABLET / ORALABRLD2007-11-0931067a03dcf5…
2025-08-23 18:47 UTC2025-08N019892-001DILAUDID8MGTABLET / ORALABRLD, RS1992-12-076a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019892-002DILAUDID4MGTABLET / ORALABRLD2007-11-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019892-003DILAUDID2MGTABLET / ORALABRLD2007-11-096a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019892-001DILAUDID8MGTABLET / ORALABRLD, RS1992-12-07fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019892-002DILAUDID4MGTABLET / ORALABRLD2007-11-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019892-003DILAUDID2MGTABLET / ORALABRLD2007-11-09fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019892-001DILAUDID8MGTABLET / ORALABRLD, RS1992-12-07b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019892-002DILAUDID4MGTABLET / ORALABRLD2007-11-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019892-003DILAUDID2MGTABLET / ORALABRLD2007-11-09b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019892-001DILAUDID8MGTABLET / ORALABRLD, RS1992-12-0703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019892-002DILAUDID4MGTABLET / ORALABRLD2007-11-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019892-003DILAUDID2MGTABLET / ORALABRLD2007-11-0903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019892-001DILAUDID8MGTABLET / ORALABRLD, RS1992-12-072680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019892-002DILAUDID4MGTABLET / ORALABRLD2007-11-092680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019892-003DILAUDID2MGTABLET / ORALABRLD2007-11-092680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019892-001DILAUDID8MGTABLET / ORALABRLD, RS1992-12-075bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019892-002DILAUDID4MGTABLET / ORALABRLD2007-11-095bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019892-003DILAUDID2MGTABLET / ORALABRLD2007-11-095bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019892-001DILAUDID8MGTABLET / ORALABRLD, RS1992-12-07d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019892-002DILAUDID4MGTABLET / ORALABRLD2007-11-09d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019892-003DILAUDID2MGTABLET / ORALABRLD2007-11-09d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N019892-001DILAUDID8MGTABLET / ORALABRLD, RS1992-12-07d06236e962d9…
2024-10-29 15:01 UTC2024-10N019892-002DILAUDID4MGTABLET / ORALABRLD2007-11-09d06236e962d9…
2024-10-29 15:01 UTC2024-10N019892-003DILAUDID2MGTABLET / ORALABRLD2007-11-09d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019892-001DILAUDID8MGTABLET / ORALABRLD, RS1992-12-0779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019892-002DILAUDID4MGTABLET / ORALABRLD2007-11-0979d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019892-003DILAUDID2MGTABLET / ORALABRLD2007-11-0979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019892-001DILAUDID8MGTABLET / ORALABRLD, RS1992-12-07301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019892-002DILAUDID4MGTABLET / ORALABRLD2007-11-09301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019892-003DILAUDID2MGTABLET / ORALABRLD2007-11-09301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019892-001DILAUDID8MGTABLET / ORALABRLD, RS1992-12-071e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019892-002DILAUDID4MGTABLET / ORALABRLD2007-11-091e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019892-003DILAUDID2MGTABLET / ORALABRLD2007-11-091e350fbaab3a…
2024-05-31 18:47 UTC2024-05N019892-001DILAUDID8MGTABLET / ORALABRLD, RS1992-12-078072bd15b7f6…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N019892-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019892-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019892-003AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019892-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019892-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019892-003AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N019892-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019892-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019892-003AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019892-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019892-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019892-003AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019892-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019892-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019892-003AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019892-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019892-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019892-003AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019892-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019892-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019892-003AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019892-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019892-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019892-003AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019892-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019892-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019892-003AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N019892-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N019892-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N019892-003AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019892-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019892-002AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019892-003AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019892-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019892-002AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019892-003AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019892-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019892-002AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019892-003AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N019892-001AB18072bd15b7f6…

Observed Orange Book patent history#

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2019-12-13 00:20 UTC2019-12N019892-00165899602020-11-09Drug substance, Drug product74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N019892-00265899602020-11-09Drug substance, Drug product74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N019892-00365899602020-11-09Drug substance, Drug product74a2ff9319b5…
2020-12-22 03:56 UTC2020-12N019892-00165899602020-11-09Drug substance, Drug product8869cabd3fbd…
2020-12-22 03:56 UTC2020-12N019892-00265899602020-11-09Drug substance, Drug product8869cabd3fbd…
2020-12-22 03:56 UTC2020-12N019892-00365899602020-11-09Drug substance, Drug product8869cabd3fbd…
2020-11-12 02:37 UTC2020-11N019892-00165899602020-11-09Drug substance, Drug productc0c555d07b60…
2020-11-12 02:37 UTC2020-11N019892-00265899602020-11-09Drug substance, Drug productc0c555d07b60…
2020-11-12 02:37 UTC2020-11N019892-00365899602020-11-09Drug substance, Drug productc0c555d07b60…
2019-12-14 00:12 UTC2019-12N019892-00165899602020-11-09Drug substance, Drug product3f01610625f2…
2019-12-14 00:12 UTC2019-12N019892-00265899602020-11-09Drug substance, Drug product3f01610625f2…
2019-12-14 00:12 UTC2019-12N019892-00365899602020-11-09Drug substance, Drug product3f01610625f2…
2019-09-15 20:21 UTC2019-09N019892-00165899602020-11-09Drug substance, Drug productb00525d2431f…
2019-09-15 20:21 UTC2019-09N019892-00265899602020-11-09Drug substance, Drug productb00525d2431f…
2019-09-15 20:21 UTC2019-09N019892-00365899602020-11-09Drug substance, Drug productb00525d2431f…
2019-07-19 19:46 UTC2019-07N019892-00165899602020-11-09Drug substance, Drug productea99ee380514…
2019-07-19 19:46 UTC2019-07N019892-00265899602020-11-09Drug substance, Drug productea99ee380514…
2019-07-19 19:46 UTC2019-07N019892-00365899602020-11-09Drug substance, Drug productea99ee380514…

Additional Listing Data#

Finished product
Yes
Brand name base
Hydromorphone Hydrochloride
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
HYDROMORPHONE HYDROCHLORIDE4 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
L960UP2KRWInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
897702Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
c48e2e9a-cb5b-46b8-b6be-3dd76e80d0caAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
c92985da-a658-b186-e763-2287eda87a86Product name320250221
96c475b3-58c7-b955-d715-0111804a3e50Product name520210512
1dd54659-b775-4fa8-a858-7f0e521fbadcProduct name420200925

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
71335-9701-0Hydromorphone Hydrochloride90 in 1 BOTTLE, PLASTICTABLET90104
71335-9701-1Hydromorphone Hydrochloride30 in 1 BOTTLE, PLASTICTABLET30104
71335-9701-2Hydromorphone Hydrochloride180 in 1 BOTTLE, PLASTICTABLET180104
71335-9701-3Hydromorphone Hydrochloride120 in 1 BOTTLE, PLASTICTABLET120104
71335-9701-4Hydromorphone Hydrochloride20 in 1 BOTTLE, PLASTICTABLET20104
71335-9701-5Hydromorphone Hydrochloride25 in 1 BOTTLE, PLASTICTABLET25104
71335-9701-6Hydromorphone Hydrochloride100 in 1 BOTTLE, PLASTICTABLET100104
71335-9701-7Hydromorphone Hydrochloride60 in 1 BOTTLE, PLASTICTABLET60104
71335-9701-8Hydromorphone Hydrochloride56 in 1 BOTTLE, PLASTICTABLET56104
71335-9701-9Hydromorphone Hydrochloride140 in 1 BOTTLE, PLASTICTABLET140104

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
71335-9701-0EA - Each71335-970120b95f91-80dc-4662-88e7-a6f283b88da712025-05-14
71335-9701-1EA - Each71335-970164219e21-7222-44d7-b597-ea0ab5aa25aa12025-05-14
71335-9701-7EA - Each71335-9701ad4af359-9c1a-4093-8437-635941cd2fdf12025-05-14

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
71335-9701HYDROMORPHONE HYDROCHLORIDE TABLET [BRYANT RANCH PREPACK]103Current NDC, 10 package rows20250303_c48e2e9a-cb5b-46b8-b6be-3dd76e80d0ca.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 6 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Hydromorphone HydrochlorideHYDROMORPHONE HYDROCHLORIDEBryant Ranch Prepack2427814c-f32b-8ac5-99b8-5e886fd2d0012026-06-29Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 019892
application number: NDA019892
Hydromorphone HydrochlorideHYDROMORPHONE HYDROCHLORIDESt. Mary's Medical Park Pharmacy53ddcacc-99e4-8b21-e063-6394a90a3e792026-06-09Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 019892
application number: NDA019892
DilaudidHYDROMORPHONE HYDROCHLORIDERhodes Pharmaceuticals LLCd6b40e39-a57e-402c-b4f6-7041e832f8372026-05-14Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 019892
application number: NDA019892
Hydromorphone HydrochlorideHYDROMORPHONE HYDROCHLORIDERhodes Pharmaceuticals LLC37565441-0d95-4743-a695-d7b3326f58a12026-05-14Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 019892
application number: NDA019892
Hydromorphone HydrochlorideHYDROMORPHONE HYDROCHLORIDEBryant Ranch Prepackc48e2e9a-cb5b-46b8-b6be-3dd76e80d0ca2026-04-10Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 019892
application number: NDA019892
ndc (product): 71335-9701
Hydromorphone HydrochlorideHYDROMORPHONE HYDROCHLORIDEASCLEMED USA INC.18f6f54e-1537-4181-9d07-54ddf881a9ee2025-12-04Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 019892
application number: NDA019892

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
897702HYDROmorphone HCl 4 MG Oral TabletPSNc48e2e9a-cb5b-46b8-b6be-3dd76e80d0ca104
897702hydromorphone hydrochloride 4 MG Oral TabletSCDc48e2e9a-cb5b-46b8-b6be-3dd76e80d0ca104

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
71335-9701-07133597010090 TABLET in 1 BOTTLE, PLASTIC (71335-9701-0) 90 tablet2025-02-26NoNoCurrent
71335-9701-17133597010130 TABLET in 1 BOTTLE, PLASTIC (71335-9701-1) 30 tablet2026-01-12NoNoCurrent
71335-9701-271335970102180 TABLET in 1 BOTTLE, PLASTIC (71335-9701-2) 180 tablet2026-04-10NoNoCurrent
71335-9701-371335970103120 TABLET in 1 BOTTLE, PLASTIC (71335-9701-3) 120 tablet2026-04-10NoNoCurrent
71335-9701-47133597010420 TABLET in 1 BOTTLE, PLASTIC (71335-9701-4) 20 tablet2026-04-10NoNoCurrent
71335-9701-57133597010525 TABLET in 1 BOTTLE, PLASTIC (71335-9701-5) 25 tablet2026-04-10NoNoCurrent
71335-9701-671335970106100 TABLET in 1 BOTTLE, PLASTIC (71335-9701-6) 100 tablet2026-04-10NoNoCurrent
71335-9701-77133597010760 TABLET in 1 BOTTLE, PLASTIC (71335-9701-7) 60 tablet2024-07-30NoNoCurrent
71335-9701-87133597010856 TABLET in 1 BOTTLE, PLASTIC (71335-9701-8) 56 tablet2026-04-10NoNoCurrent
71335-9701-971335970109140 TABLET in 1 BOTTLE, PLASTIC (71335-9701-9) 140 tablet2026-04-10NoNoCurrent