memantine hydrochloride

Product NDC
71610-011
11-digit product format
716100011
Labeler code
71610
Product ID
71610-011_f384e3d8-d9fd-481c-b924-4bf98dfb5bdf
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
memantine hydrochloride
Dosage form
TABLET
Route
ORAL
Labeler
Aphena Pharma Solutions - Tennessee, LLC
Application
NDA021487
Marketing category
NDA
Marketing start
2015-04-01
Substance
MEMANTINE HYDROCHLORIDE
Active strength
10 mg/1
Pharmacologic classes
N-methyl-D-aspartate Receptor Antagonist [EPC], NMDA Receptor Antagonists [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N021487-001NAMENDAMEMANTINE HYDROCHLORIDE5MGTABLET / ORALRLD2003-10-16
N021487-002NAMENDAMEMANTINE HYDROCHLORIDE10MGTABLET / ORALRLD2003-10-16

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N021487-001NAMENDA5MGTABLET / ORALRLD2003-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N021487-002NAMENDA10MGTABLET / ORALRLD2003-10-16caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-16011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-1631067a03dcf5…
2025-08-23 18:47 UTC2025-08N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-166a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-16fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-16b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-16b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-1603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-1603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-162680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-162680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-165bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-165bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-16d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-16d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-16d06236e962d9…
2024-10-29 15:01 UTC2024-10N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-16d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-1679d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-1679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-16301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-16301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-161e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-161e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-168072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-168072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-165c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-165c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-165d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-165d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-164b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-164b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-1674a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-1674a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-16bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-16bb7c543d1eb4…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 80 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N021487-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021487-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021487-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021487-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N021487-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021487-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021487-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021487-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021487-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021487-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021487-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021487-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021487-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021487-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021487-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021487-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021487-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021487-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021487-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N021487-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021487-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021487-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021487-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021487-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021487-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021487-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021487-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021487-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021487-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021487-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021487-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021487-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021487-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021487-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021487-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021487-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021487-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021487-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021487-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12N021487-002AB1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
memantine hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
MEMANTINE HYDROCHLORIDE10 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
JY0WD0UA60Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
996561Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
c8f5c20b-4573-44c5-89fc-4da11b2e1fe1Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
94db636e-a074-45fd-8e8d-331920a99436Product name420250103
941773f8-a40e-0684-da08-ff9a143e6368Product name720231219
5b597f00-4538-4686-aa4e-3c60ed3788c8Product name220210511
1836e79a-a4d1-4087-2f2e-f878e8a1fef2Product name920151209

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
71610-011-18memantine hydrochloride3000 in 1 BOTTLETABLET30001

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
71610-011-18EA - Each71610-0111b060e7e-beb9-49ee-bc4e-5c93800093d712018-04-19

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
71610-011MEMANTINE HYDROCHLORIDE TABLET [APHENA PHARMA SOLUTIONS - TENNESSEE, LLC]1Current NDC, Legacy NDC, 1 package rows20171201_c8f5c20b-4573-44c5-89fc-4da11b2e1fe1.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
memantine hydrochlorideMEMANTINE HYDROCHLORIDECardinal Health 107, LLCe5754973-e73b-4a25-abb4-80f91880f0182026-06-05Warnings, Adverse reactionsExact identifier
application applno (NDA): 021487
application number: NDA021487
memantine hydrochlorideMEMANTINE HYDROCHLORIDEActavis Pharma, Inc.72973b46-f307-4a9e-8fb1-ad2cbccfd7362018-11-01Warnings, Adverse reactionsExact identifier
application applno (NDA): 021487
application number: NDA021487
memantine hydrochlorideMEMANTINE HYDROCHLORIDEAphena Pharma Solutions - Tennessee, LLCc8f5c20b-4573-44c5-89fc-4da11b2e1fe12017-11-30Warnings, Adverse reactionsExact identifier
application applno (NDA): 021487
application number: NDA021487
ndc (product): 71610-011

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
996561memantine HCl 10 MG Oral TabletPSNc8f5c20b-4573-44c5-89fc-4da11b2e1fe11
996561memantine hydrochloride 10 MG Oral TabletSCDc8f5c20b-4573-44c5-89fc-4da11b2e1fe11

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
71610-011-18716100011183000 TABLET in 1 BOTTLE (71610-011-18) 3000 tablet2017-11-150000-00-00NoNoCurrent