CYCLOSPORINE

Product NDC
71656-012
11-digit product format
716560012
Labeler code
71656
Product ID
71656-012_458a84bc-12a1-5159-e063-6394a90ac45c
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
CYCLOSPORINE
Dosage form
EMULSION
Route
OPHTHALMIC
Labeler
Saptalis Pharmaceuticals, LLC
Application
ANDA211943
Marketing category
ANDA
Marketing start
2025-12-12
Substance
CYCLOSPORINE
Active strength
.5 mg/mL
Pharmacologic classes
Calcineurin Inhibitor Immunosuppressant [EPC], Calcineurin Inhibitors [MoA], Cytochrome P450 3A4 Inhibitors [MoA], P-Glycoprotein Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A211943-001CYCLOSPORINECYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-07-05

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A211943-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A211943-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-07-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211943-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-07-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08A211943-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-07-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211943-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-07-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211943-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-07-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211943-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-07-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211943-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-07-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211943-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-07-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211943-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-07-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211943-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-07-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211943-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-07-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211943-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-07-05301d65b070ca…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A211943-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-07-05a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A211943-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211943-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A211943-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211943-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211943-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211943-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211943-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211943-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211943-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211943-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211943-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211943-001AB1301d65b070ca…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A211943-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
CYCLOSPORINE
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CYCLOSPORINE.5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
83HN0GTJ6DInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2572292Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
ff4dc2fc-667a-489a-b798-8d11cddfe716Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
1be408a0-e15a-4092-b35e-4e294e65196fProduct name320240216
b3fdee3e-0c46-442f-aad5-aa71941d5621Product name120231023
78fb0708-fce5-decd-6611-5a9fbe3e3decProduct name320230327
54840517-000d-4fcb-b976-a6ddd102faa0Product name120220120
a5ba3bd0-8411-4005-ac3b-a41d8ee0633aProduct name120181029
b1c0d609-8b97-06ee-2cd0-5652a4b1d019Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
71656-012-30CYCLOSPORINE5 in 1 POUCHEMULSION51
71656-012-30CYCLOSPORINE6 in 1 CARTONEMULSION61
71656-012-60CYCLOSPORINE12 in 1 CARTONEMULSION121
71656-012-60CYCLOSPORINE5 in 1 POUCHEMULSION51

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
CYCLOSPORINECYCLOSPORINESaptalis Pharmaceuticals, LLCff4dc2fc-667a-489a-b798-8d11cddfe7162025-12-09Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211943
application number: ANDA211943
ndc (product): 71656-012

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2572292cycloSPORINE 0.05 % in 0.4 ML Ophthalmic EmulsionPSNff4dc2fc-667a-489a-b798-8d11cddfe7161
25722920.4 ML cyclosporine 0.5 MG/ML Ophthalmic SuspensionSCDff4dc2fc-667a-489a-b798-8d11cddfe7161
2572292cyclosporine 0.05 % per 0.4 ML Ophthalmic EmulsionSYff4dc2fc-667a-489a-b798-8d11cddfe7161
2572292cyclosporine 0.5 MG/ML per 0.4 ML Ophthalmic EmulsionSYff4dc2fc-667a-489a-b798-8d11cddfe7161

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
71656-012-30716560012306 POUCH in 1 CARTON (71656-012-30) / 5 VIAL, SINGLE-DOSE in 1 POUCH / .4 mL in 1 VIAL, SINGLE-DOSE6 pouch2025-12-12NoNoCurrent
71656-012-607165600126012 POUCH in 1 CARTON (71656-012-60) / 5 VIAL, SINGLE-DOSE in 1 POUCH / .4 mL in 1 VIAL, SINGLE-DOSE12 pouch2025-12-12NoNoCurrent