Verapamil Hydrochloride

Product NDC: 71872-7048
Requested package NDC: 71872-7048-1
11-digit product format: 718727048
Labeler code: 71872
Product ID: 71872-7048_fceba9f2-ff13-3fbf-e053-6294a90a3a89
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: Verapamil Hydrochloride
Dosage form: INJECTION
Route: INTRAVENOUS
Labeler: Medical Purchasing Solutions, LLC
Application: NDA018925
Marketing category: NDA
Marketing start: 2016-04-22
Substance: VERAPAMIL HYDROCHLORIDE
Active strength: 2.5 mg/mL
Pharmacologic classes: Calcium Channel Antagonists [MoA], Calcium Channel Blocker [EPC], Cytochrome P450 3A Inhibitors [MoA], Cytochrome P450 3A4 Inhibitors [MoA], P-Glycoprotein Inhibitors [MoA]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N018925-001	VERAPAMIL HYDROCHLORIDE	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP		1984-03-30
N018925-002	VERAPAMIL HYDROCHLORIDE	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS			2018-04-05

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-product	TE code
N018925-001	AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 86 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	Approval date	Source SHA-256
2026-09-14 22:38:34	2026-08	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS		2018-04-05	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N018925-001	VERAPAMIL HYDROCHLORIDE	5MG/2ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	1984-03-30	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N018925-002	VERAPAMIL HYDROCHLORIDE	10MG/4ML (2.5MG/ML)	SOLUTION / INTRAVENOUS	AP	2018-04-05	`74a2ff9319b5…`

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 49 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-09-14 22:38:34	2026-08	N018925-001	AP	1	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	N018925-001	AP	1	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N018925-001	AP	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N018925-001	AP	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N018925-001	AP	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N018925-001	AP	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N018925-001	AP	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N018925-001	AP	1	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N018925-001	AP	1	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N018925-001	AP	1	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N018925-001	AP	1	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N018925-001	AP	1	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N018925-001	AP	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N018925-001	AP	1	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N018925-001	AP	1	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N018925-001	AP	1	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N018925-001	AP	1	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N018925-001	AP	1	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N018925-001	AP	1	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N018925-001	AP	1	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N018925-002	AP	1	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N018925-001	AP	1	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N018925-001	AP	1	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N018925-001	AP	1	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N018925-001	AP	1	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	N018925-001	AP	1	`8869cabd3fbd…`
2020-12-22 03:56 UTC	2020-12	N018925-002	AP	1	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N018925-001	AP	1	`c0c555d07b60…`
2020-11-12 02:37 UTC	2020-11	N018925-002	AP	1	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	N018925-001	AP	1	`3f01610625f2…`
2019-12-14 00:12 UTC	2019-12	N018925-002	AP	1	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	N018925-001	AP	1	`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	N018925-002	AP	1	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N018925-001	AP	1	`ea99ee380514…`
2019-07-19 19:46 UTC	2019-07	N018925-002	AP	1	`ea99ee380514…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	N018925-001	AP	1	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	N018925-001	AP	1	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	N018925-001	AP	1	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	N018925-001	AP	1	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	N018925-001	AP	1	`9b2671bbb829…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Verapamil Hydrochloride
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
VERAPAMIL HYDROCHLORIDE	2.5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
V3888OEY5R	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1665057	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
6685248d-908e-cd07-e053-2a91aa0ac718	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
ea1f6fc8-bfc2-4421-a2eb-4e87c7c3e3c4	Product name	2	20230103
33ad674d-d105-6aa5-02fa-95ae4329b8cd	Product name	2	20180809
3279bd6d-5b02-e60b-3857-c853a2deb2dd	Product name	2	20170713
8ebb66e3-d7b3-f1e5-88aa-3369e64bb84a	Product name	1	20140508
940a1faa-2df8-cc65-be37-1b97984b4ea3	Product name	1	20140508
d3b67bc2-0e96-e3ec-06a9-90afcc07bf13	Product name	1	20140508
e2fcd66c-a043-3187-790d-b0342deb1149	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
71872-7048-1	Verapamil Hydrochloride	1 in 1 BAG	INJECTION	1		3
71872-7048-1	Verapamil Hydrochloride	2 mL in 1 VIAL	INJECTION	2		3

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
71872-7048	VERAPAMIL HYDROCHLORIDE INJECTION [MEDICAL PURCHASING SOLUTIONS, LLC]	3	Current NDC, Legacy NDC, 2 package rows	20230531_6685248d-908e-cd07-e053-2a91aa0ac718.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
VERAPAMIL HCI	VERAPAMIL HCI	HF Acquisition Co LLC, DBA HealthFirst	9a4f12ec-fe1c-a1b9-e053-2a95a90ac8e4	2024-02-26	Warnings, Adverse reactions	Exact identifier application applno (NDA): 018925 application number: NDA018925
Verapamil Hydrochloride	VERAPAMIL HYDROCHLORIDE	Medical Purchasing Solutions, LLC	6685248d-908e-cd07-e053-2a91aa0ac718	2023-05-30	Warnings, Adverse reactions	Exact identifier application applno (NDA): 018925 application number: NDA018925 ndc (package): 71872-7048-1 ndc (product): 71872-7048 ndc11 (package): 71872704801
Verapamil Hydrochloride	VERAPAMIL HYDROCHLORIDE	EXELA PHARMA SCIENCES, LLC	eff5e83b-f819-4a5b-9746-12bce328d7a7	2017-02-21	Warnings, Adverse reactions	Exact identifier application applno (NDA): 018925 application number: NDA018925
Verapamil Hydrochloride	VERAPAMIL HYDROCHLORIDE	EXELA PHARMA SCIENCES, LLC	3318e357-0660-44f4-8170-91a51bd762fb	2017-01-23	Warnings, Adverse reactions	Exact identifier application applno (NDA): 018925 application number: NDA018925

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
V3888OEY5R	VERAPAMIL HYDROCHLORIDE	152-11-4	VERAPAMIL HYDROCHLORIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1665057	verapamil HCl 5 MG in 2 ML Injection	PSN	6685248d-908e-cd07-e053-2a91aa0ac718	3
1665057	2 ML verapamil hydrochloride 2.5 MG/ML Injection	SCD	6685248d-908e-cd07-e053-2a91aa0ac718	3
1665057	verapamil HCl 5 MG per 2 ML Injection	SY	6685248d-908e-cd07-e053-2a91aa0ac718	3

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
71872-7048-1	71872704801	1 VIAL in 1 BAG (71872-7048-1) / 2 mL in 1 VIAL	1 vial	2018-02-28	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Verapamil Hydrochloride Injection, USP For Intravenous Injection Protect from light	Medical Purchasing Solutions, LLC \| EXELA PHARMA SCIENCES, LLC	2023-05-30	HUMAN PRESCRIPTION DRUG LABEL	3