DIPHENHYDRAMINE HYDROCHLORIDE

Product NDC
71872-7242
11-digit product format
718727242
Labeler code
71872
Product ID
71872-7242_fa59581e-a76f-d735-e053-6294a90acd1a
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
DIPHENHYDRAMINE HYDROCHLORIDE
Dosage form
SOLUTION
Route
ORAL
Labeler
Medical Purchasing Solutions, LLC
Application
ANDA087513
Marketing category
ANDA
Marketing start
1982-02-10
Substance
DIPHENHYDRAMINE HYDROCHLORIDE
Active strength
25 mg/10mL
Pharmacologic classes
Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A087513-001DIPHENHYDRAMINE HYDROCHLORIDEDIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALAARLD, RS1982-02-10

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A087513-001AA

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALAARLD, RS1982-02-10caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-10011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-1031067a03dcf5…
2025-08-23 18:47 UTC2025-08A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-106a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-10fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-10b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-1003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-102680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-105bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-10d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-10d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-1079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-10301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-101e350fbaab3a…
2024-05-31 18:47 UTC2024-05A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-108072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-105c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-105d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-104b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-1074a2ff9319b5…
2022-03-09 01:35 UTC2022-03A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-10bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-10782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-1087673890dc5c…
2021-03-12 10:30 UTC2021-03A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-105aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-108869cabd3fbd…
2020-11-12 02:37 UTC2020-11A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-10c0c555d07b60…
2019-12-14 00:12 UTC2019-12A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-103f01610625f2…
2019-09-15 20:21 UTC2019-09A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-10b00525d2431f…
2019-07-19 19:46 UTC2019-07A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-10ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-106a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-101c564ffb4f44…
2023-12-20 04:57 UTC2023-12A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-10ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-10a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-109b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-10a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRLD, RS1982-02-103f0d92c62455…
2023-05-13 08:27 UTC2023-05A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-10053a50430f4f…
2023-01-26 05:58 UTC2023-01A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-103bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-103a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-10f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A087513-001DIPHENHYDRAMINE HYDROCHLORIDE12.5MG/5MLELIXIR / ORALRS1982-02-10e64feba35796…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A087513-001AA1caaa826d4ba7…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A087513-001AA1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
DIPHENHYDRAMINE HYDROCHLORIDE
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
DIPHENHYDRAMINE HYDROCHLORIDE25 mg/10mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
TC2D6JAD40Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1049906Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
bf7ab250-38b0-ba29-e053-2a95a90a8f32Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
0e2e0f88-b076-afe1-4bdd-32bca4375becProduct name320250127
3e48c9c4-918d-5d23-2f0b-d2398b06be54Product name120140508
865c72dd-0d94-daac-f728-ddd4ded2a79eProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
71872-7242-1DIPHENHYDRAMINE HYDROCHLORIDE1 in 1 BAGSOLUTION12
71872-7242-1DIPHENHYDRAMINE HYDROCHLORIDE10 mL in 1 CUP, UNIT-DOSESOLUTION102

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
71872-7242DIPHENHYDRAMINE HYDROCHLORIDE SOLUTION [MEDICAL PURCHASING SOLUTIONS, LLC]2Current NDC, Legacy NDC, 2 package rows20230429_bf7ab250-38b0-ba29-e053-2a95a90a8f32.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Diphenhydramine HCLDIPHENHYDRAMINE HYDROCHLORIDERedmont Pharmaceuticals, LLCd8944f3c-acef-4ebe-9633-7d641ae95edf2026-08-03Warnings, Adverse reactionsExact identifier
application applno (ANDA): 087513
application number: ANDA087513
DIPHENHYDRAMINE HYDROCHLORIDEDIPHENHYDRAMINE HYDROCHLORIDEPAI Holdings, LLC dba PAI Pharma6fe6fe2d-4405-4e7a-a2ed-5eb367d528422024-04-05Warnings, Adverse reactionsExact identifier
application applno (ANDA): 087513
application number: ANDA087513
DIPHENHYDRAMINE HYDROCHLORIDEDIPHENHYDRAMINE HYDROCHLORIDEMedical Purchasing Solutions, LLCbf7ab250-38b0-ba29-e053-2a95a90a8f322023-04-27Warnings, Adverse reactionsExact identifier
application applno (ANDA): 087513
application number: ANDA087513
ndc (product): 71872-7242

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1049906diphenhydrAMINE HCl 12.5 MG in 5 mL Oral SolutionPSNbf7ab250-38b0-ba29-e053-2a95a90a8f322
1049906diphenhydramine hydrochloride 2.5 MG/ML Oral SolutionSCDbf7ab250-38b0-ba29-e053-2a95a90a8f322
1049906diphenhydramine HCl 12.5 MG per 5 ML Oral SolutionSYbf7ab250-38b0-ba29-e053-2a95a90a8f322
1049906diphenhydramine hydrochloride 25 MG per 10 ML Oral SolutionSYbf7ab250-38b0-ba29-e053-2a95a90a8f322
1049906diphenhydramine hydrochloride 50 MG per 20 ML Oral SolutionSYbf7ab250-38b0-ba29-e053-2a95a90a8f322

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
71872-7242-1718727242011 CUP, UNIT-DOSE in 1 BAG (71872-7242-1) / 10 mL in 1 CUP, UNIT-DOSE2021-03-010000-00-00NoNoCurrent