neffy

Product NDC: 71872-7330
11-digit product format: 718727330
Labeler code: 71872
Product ID: 71872-7330_2d4063dc-9f4e-71de-e063-6294a90aa599
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: epinephrine
Dosage form: SPRAY
Route: NASAL
Labeler: Medical Purchasing Solutions, LLC
Application: NDA214697
Marketing category: NDA
Marketing start: 2024-08-09
Substance: EPINEPHRINE
Active strength: 2 mg/100uL
Pharmacologic classes: Adrenergic alpha-Agonists [MoA], Adrenergic beta-Agonists [MoA], Catecholamine [EPC], Catecholamines [CS], alpha-Adrenergic Agonist [EPC], beta-Adrenergic Agonist [EPC]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N214697-001	NEFFY	EPINEPHRINE	2MG/SPRAY	SPRAY / NASAL		RLD, RS	2024-08-09
N214697-002	NEFFY	EPINEPHRINE	1MG/SPRAY	SPRAY / NASAL		RLD, RS	2025-03-05

Orange Book patents#

Current patent rows page 1 of 1 · 16 matching rows.

Application-product, Patent, Expiration table
Application-product	Patent	Expiration	Use code	Coverage / status	Submission date
N214697-001	10576156	2038-02-06		Drug product	2024-08-28
N214697-001	11173209	2038-02-06	U-3979		2024-08-28
N214697-001	10682414	2039-02-06	U-3979		2024-08-28
N214697-001	11191838	2039-02-06	U-3979	Drug product	2024-08-28
N214697-001	11717571	2039-02-06	U-3979		2024-08-28
N214697-001	11744895	2039-02-06	U-3979		2024-08-28
N214697-001	11918655	2039-02-06	U-3979	Drug product	2024-08-28
N214697-001	12324838	2039-02-06		Drug product	2025-06-20
N214697-002	10576156	2038-02-06		Drug product	2025-04-03
N214697-002	11173209	2038-02-06	U-3979		2025-04-03
N214697-002	10682414	2039-02-06	U-3979		2025-04-03
N214697-002	11191838	2039-02-06	U-3979	Drug product	2025-04-03
N214697-002	11717571	2039-02-06	U-3979		2025-04-03
N214697-002	11744895	2039-02-06	U-3979		2025-04-03
N214697-002	11918655	2039-02-06	U-3979		2025-04-03
N214697-002	12324838	2039-02-06		Drug product	2025-06-20

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	RLD / RS	Approval date	Source SHA-256
2026-09-14 22:38:34	2026-08	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N214697-002	NEFFY	1MG/SPRAY	SPRAY / NASAL	RLD, RS	2025-03-05	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N214697-002	NEFFY	1MG/SPRAY	SPRAY / NASAL	RLD, RS	2025-03-05	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-002	NEFFY	1MG/SPRAY	SPRAY / NASAL	RLD, RS	2025-03-05	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N214697-002	NEFFY	1MG/SPRAY	SPRAY / NASAL	RLD, RS	2025-03-05	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N214697-002	NEFFY	1MG/SPRAY	SPRAY / NASAL	RLD, RS	2025-03-05	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`d06236e962d9…`
2026-07-26 02:55 UTC · 3 captures of this ZIP	2026-06	N214697-001	NEFFY	2MG/SPRAY	SPRAY / NASAL	RLD, RS	2024-08-09	`a50c72e98297…`
2026-07-26 02:55 UTC · 3 captures of this ZIP	2026-06	N214697-002	NEFFY	1MG/SPRAY	SPRAY / NASAL	RLD, RS	2025-03-05	`a50c72e98297…`

Observed Orange Book patent history#

Patent history page 1 of 4 · 145 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Patent	Expiration	Use code	Coverage / status	Submission date	Source SHA-256
2026-09-14 22:38:34	2026-08	N214697-001	10576156	2038-02-06		Drug product	2024-08-28	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N214697-001	11173209	2038-02-06	U-3979		2024-08-28	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N214697-001	10682414	2039-02-06	U-3979		2024-08-28	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N214697-001	11191838	2039-02-06	U-3979	Drug product	2024-08-28	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N214697-001	11717571	2039-02-06	U-3979		2024-08-28	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N214697-001	11744895	2039-02-06	U-3979		2024-08-28	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N214697-001	11918655	2039-02-06	U-3979	Drug product	2024-08-28	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N214697-001	12324838	2039-02-06		Drug product	2025-06-20	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N214697-002	10576156	2038-02-06		Drug product	2025-04-03	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N214697-002	11173209	2038-02-06	U-3979		2025-04-03	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N214697-002	10682414	2039-02-06	U-3979		2025-04-03	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N214697-002	11191838	2039-02-06	U-3979	Drug product	2025-04-03	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N214697-002	11717571	2039-02-06	U-3979		2025-04-03	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N214697-002	11744895	2039-02-06	U-3979		2025-04-03	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N214697-002	11918655	2039-02-06	U-3979		2025-04-03	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N214697-002	12324838	2039-02-06		Drug product	2025-06-20	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	N214697-001	10576156	2038-02-06		Drug product	2024-08-28	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N214697-001	11173209	2038-02-06	U-3979		2024-08-28	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N214697-001	10682414	2039-02-06	U-3979		2024-08-28	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N214697-001	11191838	2039-02-06	U-3979	Drug product	2024-08-28	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N214697-001	11717571	2039-02-06	U-3979		2024-08-28	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N214697-001	11744895	2039-02-06	U-3979		2024-08-28	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N214697-001	11918655	2039-02-06	U-3979	Drug product	2024-08-28	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N214697-001	12324838	2039-02-06		Drug product	2025-06-20	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N214697-002	10576156	2038-02-06		Drug product	2025-04-03	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N214697-002	11173209	2038-02-06	U-3979		2025-04-03	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N214697-002	10682414	2039-02-06	U-3979		2025-04-03	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N214697-002	11191838	2039-02-06	U-3979	Drug product	2025-04-03	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N214697-002	11717571	2039-02-06	U-3979		2025-04-03	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N214697-002	11744895	2039-02-06	U-3979		2025-04-03	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N214697-002	11918655	2039-02-06	U-3979		2025-04-03	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N214697-002	12324838	2039-02-06		Drug product	2025-06-20	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N214697-001	10576156	2038-02-06		Drug product	2024-08-28	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-001	11173209	2038-02-06	U-3979		2024-08-28	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-001	10682414	2039-02-06	U-3979		2024-08-28	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-001	11191838	2039-02-06	U-3979	Drug product	2024-08-28	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-001	11717571	2039-02-06	U-3979		2024-08-28	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-001	11744895	2039-02-06	U-3979		2024-08-28	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-001	11918655	2039-02-06	U-3979	Drug product	2024-08-28	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N214697-001	12324838	2039-02-06		Drug product	2025-06-20	`011fe1cb6892…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: neffy
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
EPINEPHRINE	2 mg/100uL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
YKH834O4BH	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
2693442	Internal RxNorm lookup
2693448	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
2d4063e8-f56c-6902-e063-6294a90a0d40	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
0b4ec9ca-d305-43fc-88dd-7a510313efe0	Product name	1	20260105
bb209f42-a85f-4fee-9d3d-c9dded168625	Product name	1	20251208
49628fc7-2031-4c28-bd31-0ef3aa8f44a3	Product name	3	20251118
cbf85893-59ef-423f-87d4-a573c000a8b9	Product name	8	20250731
b5b1095b-40cd-8a9e-b111-502545045b07	Product name	4	20250325
e190029e-423b-473c-8e04-2ada59b5b711	Product name	1	20250314
e0031c74-3853-42bc-8e10-86dbbe83992e	Product name	2	20231116
f7046b89-2016-499a-adc6-78479172abc6	Product name	1	20230425
2686d634-e712-4007-8dbf-3d37c6c4d71f	Product name	1	20181121
fa8b5901-e681-426f-82fe-54f6d81ec698	Product name	4	20180619
bd49bb86-2d32-4a7a-a594-eeda2e29af42	Product name	1	20180118
c08ab52f-2fc8-4409-9d9f-ed8edc0bd070	Product name	1	20171221
3becbe78-12d9-4ad2-9b4c-1e36f8d1303a	Product name	1	20170815

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
71872-7330-1	neffy	1 in 1 BLISTER PACK	SPRAY	1		1
71872-7330-1	neffy	1 in 1 BAG	SPRAY	1		1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
71872-7330	NEFFY (EPINEPHRINE) SPRAY [MEDICAL PURCHASING SOLUTIONS, LLC]	1	Current NDC, 2 package rows	20250205_2d4063e8-f56c-6902-e063-6294a90a0d40.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
neffy	EPINEPHRINE	Sportpharm LLC	2052f9db-7d76-443b-b702-b6b499f9a4b8	2026-04-24	Warnings, Adverse reactions	Exact identifier application applno (NDA): 214697 application number: NDA214697
neffy	EPINEPHRINE	ARS Pharmaceuticals Operations, Inc.	a1758142-a905-401d-8961-05829f51023a	2026-04-09	Warnings, Adverse reactions	Exact identifier application applno (NDA): 214697 application number: NDA214697
neffy	EPINEPHRINE	Medical Purchasing Solutions, LLC	2d4063e8-f56c-6902-e063-6294a90a0d40	2025-02-03	Warnings, Adverse reactions	Exact identifier application applno (NDA): 214697 application number: NDA214697 ndc (product): 71872-7330

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
YKH834O4BH	EPINEPHRINE	51-43-4	EPINEPHRINE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
2693442	EPINEPHrine 2 MG in 0.1 ML Nasal Spray	PSN	2d4063e8-f56c-6902-e063-6294a90a0d40	1
2693448	neffy 2 MG in 0.1 ML Nasal Spray	PSN	2d4063e8-f56c-6902-e063-6294a90a0d40	1
2693448	epinephrine 20 MG/ML Nasal Spray [Neffy]	SBD	2d4063e8-f56c-6902-e063-6294a90a0d40	1
2693442	epinephrine 20 MG/ML Nasal Spray	SCD	2d4063e8-f56c-6902-e063-6294a90a0d40	1
2693442	epinephrine 2 MG per 0.1 ML Nasal Spray	SY	2d4063e8-f56c-6902-e063-6294a90a0d40	1
2693448	Neffy 2 MG per 0.1 ML Nasal Spray	SY	2d4063e8-f56c-6902-e063-6294a90a0d40	1
2693448	Neffy 20 MG/ML Nasal Spray	SY	2d4063e8-f56c-6902-e063-6294a90a0d40	1

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Sample	Exclude flag	Status
71872-7330-1	71872733001	1 BLISTER PACK in 1 BAG (71872-7330-1) / 1 VIAL, SINGLE-DOSE in 1 BLISTER PACK / 100 uL in 1 VIAL, SINGLE-DOSE	1 blister pack	2025-01-16	No	No	Current