Ibuprofen

Product NDC
71921-180
11-digit product format
719210180
Labeler code
71921
Product ID
71921-180_1f260910-03d9-fa2f-e063-6294a90ac0b9
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Ibuprofen
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Florida Pharmaceutical Products, LLC
Application
ANDA071268
Marketing category
ANDA
Marketing start
2021-10-21
Substance
IBUPROFEN
Active strength
400 mg/1
Pharmacologic classes
Anti-Inflammatory Agents, Non-Steroidal [CS], Cyclooxygenase Inhibitors [MoA], Nonsteroidal Anti-inflammatory Drug [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A071268-001IBUPROFENIBUPROFEN600MGTABLET / ORALAB1986-10-15
A071268-002IBUPROFENIBUPROFEN400MGTABLET / ORALAB1986-10-15
A071268-003IBUPROFENIBUPROFEN800MGTABLET / ORALAB1988-07-01

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
A071268-001AB
A071268-002AB
A071268-003AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A071268-001IBUPROFEN600MGTABLET / ORALAB1986-10-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02A071268-002IBUPROFEN400MGTABLET / ORALAB1986-10-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02A071268-003IBUPROFEN800MGTABLET / ORALAB1988-07-01011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A071268-001IBUPROFEN600MGTABLET / ORALAB1986-10-1531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A071268-002IBUPROFEN400MGTABLET / ORALAB1986-10-1531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A071268-003IBUPROFEN800MGTABLET / ORALAB1988-07-0131067a03dcf5…
2025-08-23 18:47 UTC2025-08A071268-001IBUPROFEN600MGTABLET / ORALAB1986-10-156a471c1ec25d…
2025-08-23 18:47 UTC2025-08A071268-002IBUPROFEN400MGTABLET / ORALAB1986-10-156a471c1ec25d…
2025-08-23 18:47 UTC2025-08A071268-003IBUPROFEN800MGTABLET / ORALAB1988-07-016a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A071268-001IBUPROFEN600MGTABLET / ORALAB1986-10-15fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A071268-002IBUPROFEN400MGTABLET / ORALAB1986-10-15fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A071268-003IBUPROFEN800MGTABLET / ORALAB1988-07-01fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A071268-001IBUPROFEN600MGTABLET / ORALAB1986-10-15b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A071268-002IBUPROFEN400MGTABLET / ORALAB1986-10-15b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A071268-003IBUPROFEN800MGTABLET / ORALAB1988-07-01b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A071268-001IBUPROFEN600MGTABLET / ORALAB1986-10-1503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A071268-002IBUPROFEN400MGTABLET / ORALAB1986-10-1503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A071268-003IBUPROFEN800MGTABLET / ORALAB1988-07-0103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A071268-001IBUPROFEN600MGTABLET / ORALAB1986-10-152680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A071268-002IBUPROFEN400MGTABLET / ORALAB1986-10-152680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A071268-003IBUPROFEN800MGTABLET / ORALAB1988-07-012680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A071268-001IBUPROFEN600MGTABLET / ORALAB1986-10-155bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A071268-002IBUPROFEN400MGTABLET / ORALAB1986-10-155bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A071268-003IBUPROFEN800MGTABLET / ORALAB1988-07-015bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A071268-001IBUPROFEN600MGTABLET / ORALAB1986-10-15d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A071268-002IBUPROFEN400MGTABLET / ORALAB1986-10-15d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A071268-003IBUPROFEN800MGTABLET / ORALAB1988-07-01d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A071268-001IBUPROFEN600MGTABLET / ORALAB1986-10-15d06236e962d9…
2024-10-29 15:01 UTC2024-10A071268-002IBUPROFEN400MGTABLET / ORALAB1986-10-15d06236e962d9…
2024-10-29 15:01 UTC2024-10A071268-003IBUPROFEN800MGTABLET / ORALAB1988-07-01d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A071268-001IBUPROFEN600MGTABLET / ORALAB1986-10-1579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A071268-002IBUPROFEN400MGTABLET / ORALAB1986-10-1579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A071268-003IBUPROFEN800MGTABLET / ORALAB1988-07-0179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A071268-001IBUPROFEN600MGTABLET / ORALAB1986-10-15301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A071268-002IBUPROFEN400MGTABLET / ORALAB1986-10-15301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A071268-003IBUPROFEN800MGTABLET / ORALAB1988-07-01301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A071268-001IBUPROFEN600MGTABLET / ORALAB1986-10-151e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A071268-002IBUPROFEN400MGTABLET / ORALAB1986-10-151e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A071268-003IBUPROFEN800MGTABLET / ORALAB1988-07-011e350fbaab3a…
2024-05-31 18:47 UTC2024-05A071268-001IBUPROFEN600MGTABLET / ORALAB1986-10-158072bd15b7f6…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A071268-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A071268-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A071268-003AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A071268-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A071268-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A071268-003AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A071268-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A071268-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A071268-003AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A071268-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A071268-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A071268-003AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A071268-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A071268-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A071268-003AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A071268-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A071268-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A071268-003AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A071268-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A071268-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A071268-003AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A071268-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A071268-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A071268-003AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A071268-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A071268-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A071268-003AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A071268-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A071268-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A071268-003AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A071268-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A071268-002AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A071268-003AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A071268-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A071268-002AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A071268-003AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A071268-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A071268-002AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A071268-003AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A071268-001AB18072bd15b7f6…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
IbuprofenIBUPROFENMajor Pharmaceuticals42b6faf5-ef47-6a7a-e063-6394a90ac4092026-02-05Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 071268
application number: ANDA071268
IbuprofenIBUPROFENNuCare Pharmaceuticals,Inc.f4d6372a-d560-0e14-e053-2a95a90a435a2024-12-13Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 071268
application number: ANDA071268
IbuprofenIBUPROFENFlorida Pharmaceutical Products, LLCc1733fdb-5eed-2094-e053-2995a90a6c8e2024-08-08Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 071268
application number: ANDA071268
ndc (product): 71921-180

Additional Listing Data#

Finished product
Yes
Brand name base
Ibuprofen
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
IBUPROFEN400 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
WK2XYI10QMInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
197805Internal RxNorm lookup
197806Internal RxNorm lookup
197807Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
c1733fdb-5eed-2094-e053-2995a90a6c8eAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
1e73f975-1ce7-705e-2bcf-788b1b5e24baProduct name520251124
16cde546-8deb-4df2-a072-dab5566ede95Product name120231003
f6d1b8d7-3bd1-4248-eddd-b60565c88015Product name420230808
874f4e63-49d2-5150-5d77-052172814ebdProduct name620230105
557673c2-8256-b351-e863-4ec71a5a64b0Product name220160714
dbc9a339-6215-4e94-9546-57a3b34902ceProduct name120160517
61c18d4e-b552-5478-8fc0-df38b93e3100Product name120140508
7b2938c9-7eb7-e312-ae90-f54f4240361eProduct name120140508
997601aa-bb5f-6971-6b90-a21132c12c7bProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
71921-180-01Ibuprofen100 in 1 BOTTLETABLET, FILM COATED1005
71921-180-50Ibuprofen500 in 1 BOTTLETABLET, FILM COATED5005

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
71921-180-01EA - Each71921-180c5ada62f-37ec-4a4f-a622-ba946c0829f712021-12-08
71921-180-50EA - Each71921-1802389491e-9f97-4f8b-b908-454f00f5f3cb12021-12-08

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
71921-180IBUPROFEN TABLET, FILM COATED [FLORIDA PHARMACEUTICAL PRODUCTS, LLC]5Current NDC, Legacy NDC, 2 package rows20240809_c1733fdb-5eed-2094-e053-2995a90a6c8e.zip

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
197805ibuprofen 400 MG Oral TabletPSNc1733fdb-5eed-2094-e053-2995a90a6c8e5
197806ibuprofen 600 MG Oral TabletPSNc1733fdb-5eed-2094-e053-2995a90a6c8e5
197807ibuprofen 800 MG Oral TabletPSNc1733fdb-5eed-2094-e053-2995a90a6c8e5
197805ibuprofen 400 MG Oral TabletSCDc1733fdb-5eed-2094-e053-2995a90a6c8e5
197806ibuprofen 600 MG Oral TabletSCDc1733fdb-5eed-2094-e053-2995a90a6c8e5
197807ibuprofen 800 MG Oral TabletSCDc1733fdb-5eed-2094-e053-2995a90a6c8e5
197805ibuprofen 400 MG Oral TabletPSNf4d6372a-d560-0e14-e053-2a95a90a435a3
197805ibuprofen 400 MG Oral TabletSCDf4d6372a-d560-0e14-e053-2a95a90a435a3
197805ibuprofen 400 MG Oral TabletPSNe42c49db-7e6e-5fac-e053-2995a90a7c8a1
197805ibuprofen 400 MG Oral TabletSCDe42c49db-7e6e-5fac-e053-2995a90a7c8a1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
71921-180-0171921018001100 TABLET, FILM COATED in 1 BOTTLE (71921-180-01) 2021-10-210000-00-00NoNoCurrent
71921-180-5071921018050500 TABLET, FILM COATED in 1 BOTTLE (71921-180-50) 2021-10-210000-00-00NoNoCurrent