Brimonidine Tartrate

Product NDC
71921-185
11-digit product format
719210185
Labeler code
71921
Product ID
71921-185_81960280-6045-44e8-a499-6f737a92c7f2
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Brimonidine Tartrate
Dosage form
SOLUTION/ DROPS
Route
OPHTHALMIC
Labeler
Florida Pharmaceutical Products, LLC
Application
ANDA091691
Marketing category
ANDA
Marketing start
2022-01-15
Substance
BRIMONIDINE TARTRATE
Active strength
2 mg/mg
Pharmacologic classes
Adrenergic alpha-Agonists [MoA], alpha-Adrenergic Agonist [EPC]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A091691-001BRIMONIDINE TARTRATEBRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A091691-001AT

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-1831067a03dcf5…
2025-08-23 18:47 UTC2025-08A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-186a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-1803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-182680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-185bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-1879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-181e350fbaab3a…
2024-05-31 18:47 UTC2024-05A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-188072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-185c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-185d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-184b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-1874a2ff9319b5…
2022-03-09 01:35 UTC2022-03A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-1887673890dc5c…
2021-03-12 10:30 UTC2021-03A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-185aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-188869cabd3fbd…
2020-11-12 02:37 UTC2020-11A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18c0c555d07b60…
2019-12-14 00:12 UTC2019-12A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-183f01610625f2…
2019-09-15 20:21 UTC2019-09A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18b00525d2431f…
2019-07-19 19:46 UTC2019-07A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-186a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-181c564ffb4f44…
2023-12-20 04:57 UTC2023-12A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-189b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-183f0d92c62455…
2023-05-13 08:27 UTC2023-05A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18053a50430f4f…
2023-01-26 05:58 UTC2023-01A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-183bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-183a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A091691-001BRIMONIDINE TARTRATE0.2%SOLUTION/DROPS / OPHTHALMICAT2014-11-18cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A091691-001AT1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A091691-001AT131067a03dcf5…
2025-08-23 18:47 UTC2025-08A091691-001AT16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A091691-001AT1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A091691-001AT1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A091691-001AT103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A091691-001AT12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A091691-001AT15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A091691-001AT1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A091691-001AT1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A091691-001AT179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A091691-001AT1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A091691-001AT11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A091691-001AT18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A091691-001AT15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A091691-001AT15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A091691-001AT14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A091691-001AT174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A091691-001AT1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A091691-001AT1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A091691-001AT187673890dc5c…
2021-03-12 10:30 UTC2021-03A091691-001AT15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A091691-001AT18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A091691-001AT1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A091691-001AT13f01610625f2…
2019-09-15 20:21 UTC2019-09A091691-001AT1b00525d2431f…
2019-07-19 19:46 UTC2019-07A091691-001AT1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A091691-001AT16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A091691-001AT11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A091691-001AT1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A091691-001AT1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A091691-001AT19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A091691-001AT1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A091691-001AT13f0d92c62455…
2023-05-13 08:27 UTC2023-05A091691-001AT1053a50430f4f…
2023-01-26 05:58 UTC2023-01A091691-001AT13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A091691-001AT13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A091691-001AT1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A091691-001AT1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A091691-001AT1cb3db0bc1861…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Brimonidine TartrateBRIMONIDINE TARTRATEFlorida Pharmaceutical Products, LLCa25f7abf-e066-4d16-a0ba-6150bdace81d2026-01-28Warnings, Adverse reactionsExact identifier
application applno (ANDA): 091691
application number: ANDA091691
ndc (product): 71921-185
Brimonidine TartrateBRIMONIDINE TARTRATEIndoco Remedies Limited383421a5-5d33-4f15-88f4-8b66fcbfac712018-12-27Warnings, Adverse reactionsExact identifier
application applno (ANDA): 091691
application number: ANDA091691

Additional Listing Data#

Finished product
Yes
Brand name base
Brimonidine Tartrate
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BRIMONIDINE TARTRATE2 mg/mg

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4S9CL2DY2HInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
861200Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
a25f7abf-e066-4d16-a0ba-6150bdace81dAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
c6c0c444-a6ba-2fb5-a7bc-7f0443fa5791Product name420251208
8ec6541e-9842-115f-62bf-f7c9ab3aeddbProduct name320250805
39b7fcf4-8865-6d40-d24d-9b8c28bd6345Product name520250123
c93ffd9a-5bad-44d8-b5e5-16ef4d2fee72Product name120220316

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
71921-185-05Brimonidine Tartrate05 mg in 1 BOTTLE, PLASTICSOLUTION/ DROPS054
71921-185-10Brimonidine Tartrate10 mg in 1 BOTTLE, PLASTICSOLUTION/ DROPS104
71921-185-15Brimonidine Tartrate15 mg in 1 BOTTLE, PLASTICSOLUTION/ DROPS154

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
71921-185-05ML - Milliliter71921-1851d10cb4d-273b-4531-9465-1f4b9df0146c12022-06-06
71921-185-10ML - Milliliter71921-18553c82a56-14dd-4fac-8a16-53bf1814b78812022-06-06
71921-185-15ML - Milliliter71921-1858ff98437-b8fb-497a-b718-05746e20b1f712022-06-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
71921-185BRIMONIDINE TARTRATE SOLUTION/ DROPS [FLORIDA PHARMACEUTICAL PRODUCTS, LLC]2Current NDC, Legacy NDC, 3 package rows20220115_a25f7abf-e066-4d16-a0ba-6150bdace81d.zip

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
861200brimonidine tartrate 0.2 % Ophthalmic SolutionPSNa25f7abf-e066-4d16-a0ba-6150bdace81d4
861200brimonidine tartrate 2 MG/ML Ophthalmic SolutionSCDa25f7abf-e066-4d16-a0ba-6150bdace81d4
861200brimonidine tartrate 0.2 % Ophthalmic SolutionSYa25f7abf-e066-4d16-a0ba-6150bdace81d4

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
71921-185-05719210185055 mg in 1 BOTTLE, PLASTIC (71921-185-05) 5 mg2022-01-150000-00-00NoNoCurrent
71921-185-107192101851010 mg in 1 BOTTLE, PLASTIC (71921-185-10) 10 mg2022-01-150000-00-00NoNoCurrent
71921-185-157192101851515 mg in 1 BOTTLE, PLASTIC (71921-185-15) 15 mg2022-01-150000-00-00NoNoCurrent