Acyclovir

Product NDC: 72162-1735
Requested package NDC: 72162-1735-6
11-digit product format: 721621735
Labeler code: 72162
Product ID: 72162-1735_8c615600-bebe-4c68-8803-8100d5260676
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: Acyclovir
Dosage form: TABLET
Route: ORAL
Labeler: Bryant Ranch Prepack
Application: ANDA075382
Marketing category: ANDA
Marketing start: 2009-10-22
Substance: ACYCLOVIR
Active strength: 400 mg/1
Pharmacologic classes: DNA Polymerase Inhibitors [MoA], Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC], Herpes Zoster Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC], Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor [EPC], Nucleoside Analog [EXT]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
A075382-001	ACYCLOVIR	ACYCLOVIR	400MG	TABLET / ORAL	AB		1999-04-30
A075382-002	ACYCLOVIR	ACYCLOVIR	800MG	TABLET / ORAL	AB		1999-04-30

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-product	TE code
A075382-001	AB
A075382-002	AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 86 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	Approval date	Source SHA-256
2026-09-14 22:38:34	2026-08	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	A075382-001	ACYCLOVIR	400MG	TABLET / ORAL	AB	1999-04-30	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	A075382-002	ACYCLOVIR	800MG	TABLET / ORAL	AB	1999-04-30	`74a2ff9319b5…`

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 86 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-09-14 22:38:34	2026-08	A075382-001	AB	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	A075382-002	AB	1	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	A075382-001	AB	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A075382-002	AB	1	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	A075382-001	AB	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A075382-002	AB	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A075382-001	AB	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A075382-002	AB	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A075382-001	AB	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A075382-002	AB	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A075382-001	AB	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A075382-002	AB	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A075382-001	AB	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A075382-002	AB	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A075382-001	AB	1	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A075382-002	AB	1	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A075382-001	AB	1	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A075382-002	AB	1	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A075382-001	AB	1	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A075382-002	AB	1	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A075382-001	AB	1	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A075382-002	AB	1	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A075382-001	AB	1	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A075382-002	AB	1	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A075382-001	AB	1	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A075382-002	AB	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A075382-001	AB	1	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A075382-002	AB	1	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A075382-001	AB	1	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A075382-002	AB	1	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	A075382-001	AB	1	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	A075382-002	AB	1	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A075382-001	AB	1	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A075382-002	AB	1	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	A075382-001	AB	1	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	A075382-002	AB	1	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	A075382-001	AB	1	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	A075382-002	AB	1	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	A075382-001	AB	1	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	A075382-002	AB	1	`74a2ff9319b5…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Acyclovir
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
ACYCLOVIR	400 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
X4HES1O11F	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
197311	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
f09cdb3f-dfd2-4e47-bb5e-a5d26d8bcc89	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
33190c02-82e1-0a4d-d716-9ccd23588463	Product name	5	20250225
c367d1da-5a72-8966-6d11-1eb9a73ae758	Product name	3	20231115
5518bf13-db2f-2e9c-3679-e70ecf03752c	Product name	9	20210614
27897900-0e40-497b-97e1-88057e68fe6c	Product name	4	20200710
ca834e59-e669-229c-9288-0ccb76dc373e	Product name	9	20200220
d7f95c49-d3e1-4bbc-a389-e9cd73f59a28	Product name	1	20190702
fb15b394-3715-4c87-a447-421489aa8739	Product name	3	20170727
7bdc4804-3832-c0df-e519-72b6d47c9792	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
72162-1735-1	Acyclovir	120 in 1 BOTTLE, PLASTIC	TABLET	120	102
72162-1735-2	Acyclovir	20 in 1 BOTTLE, PLASTIC	TABLET	20	102
72162-1735-3	Acyclovir	30 in 1 BOTTLE, PLASTIC	TABLET	30	102
72162-1735-4	Acyclovir	28 in 1 BOTTLE, PLASTIC	TABLET	28	102
72162-1735-5	Acyclovir	10 in 1 BOTTLE, PLASTIC	TABLET	10	102
72162-1735-6	Acyclovir	60 in 1 BOTTLE, PLASTIC	TABLET	60	102
72162-1735-7	Acyclovir	50 in 1 BOTTLE, PLASTIC	TABLET	50	102

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
72162-1735-1	EA - Each	72162-1735	bf807b4a-bf13-47b0-92f0-62c6bc84e4db	1	2023-10-16
72162-1735-2	EA - Each	72162-1735	999a483e-5326-4ee8-87e6-8fd123c683a9	1	2023-10-16
72162-1735-3	EA - Each	72162-1735	38ad4994-e407-46b8-9f2b-ed6e1e7914bc	1	2023-10-16
72162-1735-4	EA - Each	72162-1735	60b855ee-7970-4008-a5fb-103c4ae7ea3a	1	2023-10-16
72162-1735-5	EA - Each	72162-1735	44fa26cf-3c82-408f-a845-49cec7cb696a	1	2023-10-16
72162-1735-6	EA - Each	72162-1735	b231becf-f4b5-4705-8b28-6f8972065e5c	1	2023-10-16
72162-1735-7	EA - Each	72162-1735	a8a2b11d-7516-4dab-bb64-cf00cb211cf7	1	2023-10-16

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
72162-1735	ACYCLOVIR TABLET [BRYANT RANCH PREPACK]	102	Current NDC, 7 package rows	20240919_f09cdb3f-dfd2-4e47-bb5e-a5d26d8bcc89.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 12 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Acyclovir	ACYCLOVIR	Cardinal Health 107, LLC	d8004652-86fe-4714-81d4-5e1dd2585bb4	2026-04-20	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 075382 application number: ANDA075382
Acyclovir	ACYCLOVIR	NuCare Pharmaceuticals,Inc.	c2d9940a-ce88-5fd0-e053-2a95a90a4bc8	2026-03-26	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 075382 application number: ANDA075382
Acyclovir	ACYCLOVIR	AvPAK	6e203fa9-ee97-1e08-8d6a-fb57cfa13e19	2026-01-08	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 075382 application number: ANDA075382
Acyclovir	ACYCLOVIR	Bryant Ranch Prepack	f3cbd634-77c8-3306-bdbd-a4598b20603e	2024-10-29	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 075382 application number: ANDA075382
Acyclovir	ACYCLOVIR	Bryant Ranch Prepack	e0f17e6f-63c7-4828-8585-91fc582df30b	2024-09-06	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 075382 application number: ANDA075382
Acyclovir	ACYCLOVIR	Bryant Ranch Prepack	f09cdb3f-dfd2-4e47-bb5e-a5d26d8bcc89	2024-09-06	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 075382 application number: ANDA075382 ndc (package): 72162-1735-6 ndc (product): 72162-1735 ndc11 (package): 72162173506
Acyclovir	ACYCLOVIR	Bryant Ranch Prepack	8c5d1f30-2d31-417d-860b-7228b7baaa64	2024-09-06	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 075382 application number: ANDA075382
Acyclovir	ACYCLOVIR	Golden State Medical Supply, Inc.	785d68bc-0bbf-b69d-e053-2991aa0ac0d5	2024-09-05	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 075382 application number: ANDA075382
Acyclovir	ACYCLOVIR	Bryant Ranch Prepack	89583890-186b-4a7a-8741-41f6c5f0a99d	2024-09-05	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 075382 application number: ANDA075382
Acyclovir	ACYCLOVIR	Carlsbad Technology, Inc.	a68e610a-841c-4b69-9233-673d060561e8	2024-08-26	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 075382 application number: ANDA075382
Acyclovir	ACYCLOVIR	NuCare Pharmaceuticals,Inc.	c46d5033-b1b2-e213-e053-2995a90ae6a3	2024-08-22	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 075382 application number: ANDA075382
Acyclovir	ACYCLOVIR	Proficient Rx LP	33630a35-346e-43b6-9286-89e28ac0094a	2022-06-01	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 075382 application number: ANDA075382

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
X4HES1O11F	ACYCLOVIR	59277-89-3	ACYCLOVIR

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
197311	acyclovir 400 MG Oral Tablet	PSN	f09cdb3f-dfd2-4e47-bb5e-a5d26d8bcc89	102
197311	acyclovir 400 MG Oral Tablet	SCD	f09cdb3f-dfd2-4e47-bb5e-a5d26d8bcc89	102
197311	acycycloguanosine 400 MG Oral Tablet	SY	f09cdb3f-dfd2-4e47-bb5e-a5d26d8bcc89	102

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Sample	Exclude flag	Status
72162-1735-6	72162173506	60 TABLET in 1 BOTTLE, PLASTIC (72162-1735-6)	60 tablet	2024-09-06	No	No	Current