lofexidine hydrochloride

Product NDC
72205-246
11-digit product format
722050246
Labeler code
72205
Product ID
72205-246_19b5c932-af2d-4a0b-ac4a-ba06c53c3219
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
lofexidine hydrochloride
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Novadoz Pharmaceuticals LLC
Application
ANDA218699
Marketing category
ANDA
Marketing start
2025-02-24
Substance
LOFEXIDINE HYDROCHLORIDE
Active strength
.2 mg/1
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A218699-001LOFEXIDINE HYDROCHLORIDELOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2025-02-24

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A218699-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A218699-001LOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2025-02-24011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218699-001LOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2025-02-2431067a03dcf5…
2025-08-23 18:47 UTC2025-08A218699-001LOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2025-02-246a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218699-001LOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2025-02-24fd3edfee7708…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A218699-001LOFEXIDINE HYDROCHLORIDEEQ 0.18MG BASETABLET / ORALAB2025-02-24a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A218699-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A218699-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A218699-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A218699-001AB1fd3edfee7708…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A218699-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
lofexidine hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
LOFEXIDINE HYDROCHLORIDE.2 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
V47G1SDI1BInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2046591Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
19b5c932-af2d-4a0b-ac4a-ba06c53c3219Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
3e49fde7-51ed-4b66-8350-88f7c4d066d4Product name220250317
e2db08c6-133f-4f4f-afb4-e90a2418d6f6Product name120230320
ce6d5c06-3ae0-18a6-d5b3-8cd3cc0f8906Product name720210625
f52be47f-7aa7-46c0-b1fa-50c18dd50206Product name120201029
11ed6f83-cdd2-4637-8379-b1a1d3ae3cdeProduct name120181101
86c45a79-b9f0-4476-a27c-6e10db098497Product name120180125
d5e51f11-ad28-caa4-4b49-4143974782adProduct name120150831

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
72205-246-42lofexidine hydrochloride1 in 1 CARTONTABLET, FILM COATED11
72205-246-42lofexidine hydrochloride36 in 1 BOTTLETABLET, FILM COATED361
72205-246-43lofexidine hydrochloride1 in 1 CARTONTABLET, FILM COATED11
72205-246-43lofexidine hydrochloride96 in 1 BOTTLETABLET, FILM COATED961

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
72205-246-42EA - Each72205-2464db80c10-b057-4d9c-bcc6-c18f367f2c8f12025-05-14
72205-246-43EA - Each72205-246e4a750fd-0af7-415b-825d-59e3a095f6df12025-05-14

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
72205-246LOFEXIDINE HYDROCHLORIDE TABLET, FILM COATED [NOVADOZ PHARMACEUTICALS LLC]1Current NDC, 4 package rows20250309_19b5c932-af2d-4a0b-ac4a-ba06c53c3219.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
lofexidine hydrochlorideLOFEXIDINE HYDROCHLORIDENovadoz Pharmaceuticals LLC19b5c932-af2d-4a0b-ac4a-ba06c53c32192024-11-01Warnings, Adverse reactionsExact identifier
application applno (ANDA): 218699
application number: ANDA218699
ndc (product): 72205-246

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2046591lofexidine 0.18 MG Oral TabletPSN19b5c932-af2d-4a0b-ac4a-ba06c53c32191
2046591lofexidine 0.18 MG Oral TabletSCD19b5c932-af2d-4a0b-ac4a-ba06c53c32191
2046591lofexidine 0.18 MG (as lofexidine HCl 0.2 MG) Oral TabletSY19b5c932-af2d-4a0b-ac4a-ba06c53c32191

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
72205-246-42722050246421 BOTTLE in 1 CARTON (72205-246-42) / 36 TABLET, FILM COATED in 1 BOTTLE1 bottle2025-03-01NoNoCurrent
72205-246-43722050246431 BOTTLE in 1 CARTON (72205-246-43) / 96 TABLET, FILM COATED in 1 BOTTLE1 bottle2025-03-01NoNoCurrent