Tizanidine hydrochloride

Product NDC
72241-041
11-digit product format
722410041
Labeler code
72241
Product ID
72241-041_92a36fc0-6663-404c-9a95-9e469527b143
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Tizanidine hydrochloride
Dosage form
CAPSULE
Route
ORAL
Labeler
Modavar Pharmaceuticals LLC
Application
ANDA210021
Marketing category
ANDA
Marketing start
2017-12-29
Substance
TIZANIDINE HYDROCHLORIDE
Active strength
2 mg/1
Pharmacologic classes
Adrenergic alpha2-Agonists [MoA], Central alpha-2 Adrenergic Agonist [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A210021-001TIZANIDINE HYDROCHLORIDETIZANIDINE HYDROCHLORIDEEQ 2MG BASECAPSULE / ORALAB2019-03-26
A210021-002TIZANIDINE HYDROCHLORIDETIZANIDINE HYDROCHLORIDEEQ 4MG BASECAPSULE / ORALAB2019-03-26
A210021-003TIZANIDINE HYDROCHLORIDETIZANIDINE HYDROCHLORIDEEQ 6MG BASECAPSULE / ORALAB2019-03-26

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
A210021-001AB
A210021-002AB
A210021-003AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A210021-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASECAPSULE / ORALAB2019-03-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02A210021-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASECAPSULE / ORALAB2019-03-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02A210021-003TIZANIDINE HYDROCHLORIDEEQ 6MG BASECAPSULE / ORALAB2019-03-26011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A210021-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASECAPSULE / ORALAB2019-03-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A210021-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASECAPSULE / ORALAB2019-03-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A210021-003TIZANIDINE HYDROCHLORIDEEQ 6MG BASECAPSULE / ORALAB2019-03-2631067a03dcf5…
2025-08-23 18:47 UTC2025-08A210021-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASECAPSULE / ORALAB2019-03-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08A210021-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASECAPSULE / ORALAB2019-03-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08A210021-003TIZANIDINE HYDROCHLORIDEEQ 6MG BASECAPSULE / ORALAB2019-03-266a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A210021-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASECAPSULE / ORALAB2019-03-26fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A210021-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASECAPSULE / ORALAB2019-03-26fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A210021-003TIZANIDINE HYDROCHLORIDEEQ 6MG BASECAPSULE / ORALAB2019-03-26fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A210021-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASECAPSULE / ORALAB2019-03-26b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A210021-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASECAPSULE / ORALAB2019-03-26b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A210021-003TIZANIDINE HYDROCHLORIDEEQ 6MG BASECAPSULE / ORALAB2019-03-26b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A210021-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASECAPSULE / ORALAB2019-03-2603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A210021-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASECAPSULE / ORALAB2019-03-2603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A210021-003TIZANIDINE HYDROCHLORIDEEQ 6MG BASECAPSULE / ORALAB2019-03-2603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A210021-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASECAPSULE / ORALAB2019-03-262680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A210021-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASECAPSULE / ORALAB2019-03-262680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A210021-003TIZANIDINE HYDROCHLORIDEEQ 6MG BASECAPSULE / ORALAB2019-03-262680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A210021-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASECAPSULE / ORALAB2019-03-265bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A210021-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASECAPSULE / ORALAB2019-03-265bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A210021-003TIZANIDINE HYDROCHLORIDEEQ 6MG BASECAPSULE / ORALAB2019-03-265bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A210021-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASECAPSULE / ORALAB2019-03-26d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A210021-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASECAPSULE / ORALAB2019-03-26d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A210021-003TIZANIDINE HYDROCHLORIDEEQ 6MG BASECAPSULE / ORALAB2019-03-26d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A210021-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASECAPSULE / ORALAB2019-03-26d06236e962d9…
2024-10-29 15:01 UTC2024-10A210021-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASECAPSULE / ORALAB2019-03-26d06236e962d9…
2024-10-29 15:01 UTC2024-10A210021-003TIZANIDINE HYDROCHLORIDEEQ 6MG BASECAPSULE / ORALAB2019-03-26d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A210021-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASECAPSULE / ORALAB2019-03-2679d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A210021-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASECAPSULE / ORALAB2019-03-2679d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A210021-003TIZANIDINE HYDROCHLORIDEEQ 6MG BASECAPSULE / ORALAB2019-03-2679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A210021-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASECAPSULE / ORALAB2019-03-26301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A210021-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASECAPSULE / ORALAB2019-03-26301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A210021-003TIZANIDINE HYDROCHLORIDEEQ 6MG BASECAPSULE / ORALAB2019-03-26301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A210021-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASECAPSULE / ORALAB2019-03-261e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A210021-002TIZANIDINE HYDROCHLORIDEEQ 4MG BASECAPSULE / ORALAB2019-03-261e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A210021-003TIZANIDINE HYDROCHLORIDEEQ 6MG BASECAPSULE / ORALAB2019-03-261e350fbaab3a…
2024-05-31 18:47 UTC2024-05A210021-001TIZANIDINE HYDROCHLORIDEEQ 2MG BASECAPSULE / ORALAB2019-03-268072bd15b7f6…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A210021-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A210021-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A210021-003AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A210021-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A210021-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A210021-003AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A210021-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A210021-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A210021-003AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A210021-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A210021-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A210021-003AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A210021-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A210021-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A210021-003AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A210021-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A210021-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A210021-003AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A210021-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A210021-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A210021-003AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A210021-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A210021-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A210021-003AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A210021-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A210021-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A210021-003AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A210021-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A210021-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A210021-003AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A210021-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A210021-002AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A210021-003AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A210021-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A210021-002AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A210021-003AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A210021-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A210021-002AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A210021-003AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A210021-001AB18072bd15b7f6…

Additional Listing Data#

Finished product
Yes
Brand name base
Tizanidine hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
TIZANIDINE HYDROCHLORIDE2 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
B53E3NMY5CInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
485484Internal RxNorm lookup
485485Internal RxNorm lookup
485486Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
f8288ccd-6c66-415e-a06b-758971afe9a0Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
a0ff02d8-b711-423c-b7d1-ada00d81c743Product name120250805
9fd28b3a-d1bb-a2ce-ffa3-c3dd28536a01Product name820250313
b404127e-1c01-47bb-874e-db1e0b6bd9afProduct name420250313

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
72241-041-07Tizanidine hydrochloride150 in 1 BOTTLECAPSULE1502

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
72241-041TIZANIDINE HYDROCHLORIDE CAPSULE [MODAVAR PHARMACEUTICALS LLC]2Current NDC, Legacy NDC, 1 package rows20250418_f8288ccd-6c66-415e-a06b-758971afe9a0.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Tizanidine hydrochlorideTIZANIDINE HYDROCHLORIDEKanchan Healthcare Inc22ea819a-2aaa-44e0-a350-258541b112202026-04-08Warnings, Adverse reactionsExact identifier
application applno (ANDA): 210021
application number: ANDA210021
Tizanidine hydrochlorideTIZANIDINE HYDROCHLORIDEModavar Pharmaceuticals LLCf8288ccd-6c66-415e-a06b-758971afe9a02025-01-29Warnings, Adverse reactionsExact identifier
application applno (ANDA): 210021
application number: ANDA210021
ndc (product): 72241-041
Tizanidine hydrochlorideTIZANIDINE HYDROCHLORIDECadila Pharmaceuticals Limitedf2f4e117-0318-4bbd-aaa7-fab803714f212024-12-23Warnings, Adverse reactionsExact identifier
application applno (ANDA): 210021
application number: ANDA210021
TIZANIDINE HYDROCHLORIDETIZANIDINE HYDROCHLORIDENivagen Pharmaceuticals, Inc.c4a5b305-4265-4f90-a9ff-c16c0b936a062021-01-14Warnings, Adverse reactionsExact identifier
application applno (ANDA): 210021
application number: ANDA210021

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
485486tiZANidine HCl 2 MG Oral CapsulePSNf8288ccd-6c66-415e-a06b-758971afe9a02
485485tiZANidine HCl 4 MG Oral CapsulePSNf8288ccd-6c66-415e-a06b-758971afe9a02
485484tiZANidine HCl 6 MG Oral CapsulePSNf8288ccd-6c66-415e-a06b-758971afe9a02
485486tizanidine 2 MG Oral CapsuleSCDf8288ccd-6c66-415e-a06b-758971afe9a02
485485tizanidine 4 MG Oral CapsuleSCDf8288ccd-6c66-415e-a06b-758971afe9a02
485484tizanidine 6 MG Oral CapsuleSCDf8288ccd-6c66-415e-a06b-758971afe9a02
485486tizanidine 2 MG (as tizanidine HCl 2.288 MG) Oral CapsuleSYf8288ccd-6c66-415e-a06b-758971afe9a02
485485tizanidine 4 MG (as tizanidine HCl 4.576 MG) Oral CapsuleSYf8288ccd-6c66-415e-a06b-758971afe9a02
485484tizanidine 6 MG (as tizanidine HCl 6.87 MG) Oral CapsuleSYf8288ccd-6c66-415e-a06b-758971afe9a02

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
72241-041-0772241004107150 CAPSULE in 1 BOTTLE (72241-041-07) 150 capsule2017-12-290000-00-00NoNoCurrent