Original Antiseptic

Product NDC: 72288-318
11-digit product format: 722880318
Labeler code: 72288
Product ID: 72288-318_5ca0512c-87e9-9d6d-e063-6294a90a1303
Type: HUMAN OTC DRUG
Nonproprietary name: EUCALYPTOL, Menthol, Methyl salicylate, Thymol
Dosage form: MOUTHWASH
Route: ORAL
Labeler: Amazon.com Services LLC
Application: 505G(a)(3)
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2018-05-01
Substance: EUCALYPTOL; MENTHOL; METHYL SALICYLATE; THYMOL
Active strength: .92; .42; .6; .64 mg/mL; mg/mL; mg/mL; mg/mL
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 3 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Source date
excluded package	package	72288-318	72288-318-69	D	Discontinued by firm	2026-10-05
excluded package	package	72288-318	72288-318-77	D	Discontinued by firm	2026-10-05
excluded package	package	72288-318	72288-318-86	D	Discontinued by firm	2026-10-05

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 23 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Package NDC, Snapshot table
Captured / source date	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	72288-318-69	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	72288-318-77	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	72288-318-86	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	72288-318-77	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	72288-318-69	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	72288-318-69	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	72288-318-77	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	72288-318-69	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	72288-318-77	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	72288-318-69	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	72288-318-77	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	72288-318-69	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	72288-318-77	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	72288-318-69	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	72288-318-77	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	72288-318-69	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	72288-318-77	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	72288-318-69	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	72288-318-77	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	72288-318-69	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	72288-318-77	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	72288-318-69	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	72288-318-77	`367a005e9d99…`	`383a685ebd0f…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Original Antiseptic
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
EUCALYPTOL	.92 mg/mL
MENTHOL	.42 mg/mL
METHYL SALICYLATE	.6 mg/mL
THYMOL	.64 mg/mL

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
c6f86816-7da6-43ea-8c25-ac9758311cc5	Product name	1	20220118
dea2eded-d1e7-46bb-9a3d-f8dc20de6277	Product name	1	20190408
7792dadb-52b6-46b6-8fdf-80b1171065b5	Product name	1	20180810
252e11b6-1a9a-4283-a242-df2c129c496d	Product name	3	20170717

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
72288-318-12	Original Antiseptic	1500 mL in 1 BOTTLE, PLASTIC	MOUTHWASH	1500	14
72288-318-69	Original Antiseptic	250 mL in 1 BOTTLE, PLASTIC	MOUTHWASH	250	14
72288-318-77	Original Antiseptic	500 mL in 1 BOTTLE, PLASTIC	MOUTHWASH	500	14
72288-318-86	Original Antiseptic	1000 mL in 1 BOTTLE, PLASTIC	MOUTHWASH	1000	14

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
72288-318	ORIGINAL ANTISEPTIC (EUCALYPTOL, MENTHOL, METHYL SALICYLATE, THYMOL) MOUTHWASH [AMAZON.COM SERVICES LLC]	12	Current NDC, Legacy NDC, 4 package rows	20250519_11bfc79f-ffba-45f9-82b2-a7c19b990bb2.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Original Antiseptic	EUCALYPTOL, MENTHOL, METHYL SALICYLATE, THYMOL	Amazon.com Services LLC	11bfc79f-ffba-45f9-82b2-a7c19b990bb2	2026-03-03	Warnings, Adverse reactions	Exact identifier ndc (product): 72288-318

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
RV6J6604TK	EUCALYPTOL	470-82-6	EUCALYPTOL
LAV5U5022Y	METHYL SALICYLATE	119-36-8	METHYL SALICYLATE
3J50XA376E	THYMOL	89-83-8	THYMOL

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1043619	eucalyptol 0.092 % / menthol 0.042 % / methyl salicylate 0.06 % / thymol 0.064 % Mouthwash	PSN	11bfc79f-ffba-45f9-82b2-a7c19b990bb2	14
1043619	eucalyptol 0.92 MG/ML / menthol 0.42 MG/ML / methyl salicylate 0.6 MG/ML / thymol 0.64 MG/ML Mouthwash	SCD	11bfc79f-ffba-45f9-82b2-a7c19b990bb2	14
1043619	eucalyptol 0.092 % / menthol 0.042 % / methyl salicylate 0.06 % / thymol 0.064 % Mouthwash	SY	11bfc79f-ffba-45f9-82b2-a7c19b990bb2	14

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
72288-318-12	72288031812	1500 mL in 1 BOTTLE, PLASTIC (72288-318-12)	1500 ml	2018-05-01	0000-00-00	No	No	Current
72288-318-69	72288031869	250 mL in 1 BOTTLE, PLASTIC (72288-318-69)	250 ml	2018-05-01	0000-00-00	No	No	Current
72288-318-77	72288031877	500 mL in 1 BOTTLE, PLASTIC (72288-318-77)	500 ml	2018-05-01	0000-00-00	No	No	Current
72288-318-86	72288031886	1000 mL in 1 BOTTLE, PLASTIC (72288-318-86)	1000 ml	2018-05-01	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Basics 318.003/318AH-AI Antiseptic Mouthrinse	Amazon.com Services LLC \| Nice-Pak Products, LLC	2026-09-29	HUMAN OTC DRUG LABEL	15