MUCUS ER

Product NDC: 72288-390
11-digit product format: 722880390
Labeler code: 72288
Product ID: 72288-390_98737821-8d13-4a60-9699-714ed847b712
Type: HUMAN OTC DRUG
Nonproprietary name: guaifenesin
Dosage form: TABLET, MULTILAYER, EXTENDED RELEASE
Route: ORAL
Labeler: Amazon.com Services LLC
Application: ANDA078912
Marketing category: ANDA
Marketing start: 2026-10-15
Substance: GUAIFENESIN
Active strength: 600 mg/1
Pharmacologic classes: Decreased Respiratory Secretion Viscosity [PE], Expectorant [EPC], Increased Respiratory Secretions [PE]
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 44.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
A078912-001	GUAIFENESIN	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL			2011-11-23
A078912-002	GUAIFENESIN	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL			2020-11-05

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 83 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Approval date	Source SHA-256
2026-10-15 13:18:30	2026-09	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`c2088c7a36db…`
2026-09-14 22:38:34	2026-08	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	A078912-001	GUAIFENESIN	600MG	TABLET, EXTENDED RELEASE / ORAL	2011-11-23	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	A078912-002	GUAIFENESIN	1.2GM	TABLET, EXTENDED RELEASE / ORAL	2020-11-05	`4b0b4de00fa7…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: MUCUS ER
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
GUAIFENESIN	600 mg/1

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 2 · 27 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
good sense mucus er	GUAIFENESIN	L. Perrigo Company	def40c3f-29de-4efc-b1d3-4cb89183aaec	2026-09-03	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
mucus relief	GUAIFENESIN	CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED	51194399-6ded-4142-8880-9e810e628352	2026-07-13	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
equate mucus-er	GUAIFENESIN	WALMART INC.	a2cc6dec-388a-46bd-9cbc-1ffb6fd1aea3	2026-07-02	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
RUGBY MUCUS RELIEF ER	GUAIFENESIN	Rugby Laboratories	b82ba4cb-8e96-41cc-81c4-ab976410fa30	2026-06-15	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
equate mucus relief	GUAIFENESIN	WALMART INC.	154602ca-91c4-4030-ae77-9bf179cc95e8	2026-05-26	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
MUCUS RELIEF	GUAIFENESIN	CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED	2caa7f8e-695c-441a-a968-fcc3f527d117	2026-05-13	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
good sense mucus er	GUAIFENESIN	Redpharm Drug	4fb57f87-f761-b52e-e063-6294a90ae4ee	2026-04-18	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
Leader Mucus Relief	GUAIFENESIN	Cardinal Health 110, LLC. dba Leader	ca735722-0baa-4c85-8311-17dbce915fc5	2026-04-08	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
mucus er	GUAIFENESIN	HyVee Inc	851f49b5-34a0-4c58-90fa-51e265c7f731	2026-03-26	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
MUCUS AND CHEST CONGESTION	GUAIFENESIN	CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED	f341aa99-5339-4087-a98a-469231dfc6d0	2026-02-17	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
up and up mucus relief	GUAIFENESIN	Target Corporation	7c1598f1-1236-48d2-861b-de4715e3f3d2	2026-02-05	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
mucus er	GUAIFENESIN	HyVee Inc	74136552-55b2-4dee-9c66-3f84e9dc63d6	2026-02-03	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
MUCUS AND CHEST CONGESTION	GUAIFENESIN	CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED	f505e0bd-8881-4e51-a2fc-4e649bac3bff	2026-01-14	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
UP AND UP MUCUS RELIEF	GUAIFENESIN	Target Corporation	059cff23-b6a5-40dc-ac4e-9bcb552e9764	2025-09-22	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
Good Sense Mucus ER	GUAIFENESIN	L. Perrigo Company	30860399-d9a3-409b-bfac-00597c74b175	2025-07-16	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
basic care mucus er max	GUAIFENESIN	Amazon.com Services LLC	3552346e-4650-44c1-9233-57251a029133	2025-07-02	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
Good Neighbor Pharmacy Mucus ER	GUAIFENESIN	Amerisource Bergen	5810b584-bbfa-4dd2-b237-71520a214c09	2025-06-17	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
mucus extended release	GUAIFENESIN	CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED	9fcf96a7-bef4-4cc8-bd9e-c245ccbea17d	2025-06-17	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
Rugby Mucus Relief ER	GUAIFENESIN	Rugby Laboratories	1c579aea-c9c5-44d0-997b-f350f84ac6d0	2025-06-17	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912
DG health mucus er max	GUAIFENESIN	Dolgencorp Inc	4353d561-0e6d-4d36-b356-dd6506b5a3ee	2025-06-06	Warnings	Exact identifier application applno (ANDA): 078912 application number: ANDA078912

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
495W7451VQ	GUAIFENESIN	93-14-1	GUAIFENESIN

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Sample	Exclude flag	Status
72288-390-02	72288039002	5 BLISTER PACK in 1 CARTON (72288-390-02) / 20 TABLET, MULTILAYER, EXTENDED RELEASE in 1 BLISTER PACK	5 blister pack	2026-10-15	No	No	Current
72288-390-33	72288039033	1 BOTTLE in 1 CARTON (72288-390-33) / 60 TABLET, MULTILAYER, EXTENDED RELEASE in 1 BOTTLE (72288-390-00)	1 bottle	2026-10-15	No	No	Current
72288-390-60	72288039060	1 BOTTLE in 1 CARTON (72288-390-60) / 20 TABLET, MULTILAYER, EXTENDED RELEASE in 1 BOTTLE (72288-390-01)	1 bottle	2026-10-15	No	No	Current