EPINEPHRINE

Product NDC
72572-238
11-digit product format
725720238
Labeler code
72572
Product ID
72572-238_4a79ad00-405b-4454-a692-7f1daac4adec
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
EPINEPHRINE
Dosage form
INJECTION, SOLUTION, CONCENTRATE
Route
INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS
Labeler
CIVICA, INC.
Application
NDA215425
Marketing category
NDA
Marketing start
2025-03-13
Substance
EPINEPHRINE
Active strength
1 mg/mL
Pharmacologic classes
Adrenergic alpha-Agonists [MoA], Adrenergic beta-Agonists [MoA], Catecholamine [EPC], Catecholamines [CS], alpha-Adrenergic Agonist [EPC], beta-Adrenergic Agonist [EPC]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N215425-001EPINEPHRINEEPINEPHRINE30MG/30ML (1MG/ML)SOLUTION / INTRAMUSCULAR, INTRAVENOUS, SUBCUTANEOUSRLD, RS2025-03-13

Orange Book patents#

Current patent rows page 1 of 1 · 1 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N215425-001125392832045-01-17Drug product2026-02-05

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-01 22:54:322026-06N215425-001EPINEPHRINE30MG/30ML (1MG/ML)SOLUTION / INTRAMUSCULAR, INTRAVENOUS, SUBCUTANEOUSRLD, RS2025-03-13a50c72e98297…

Observed Orange Book patent history#

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-01 22:54:322026-06N215425-001125392832045-01-17Drug product2026-02-05a50c72e98297…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
EPINEPHRINEEPINEPHRINEFresenius Kabi USA, LLC4f83895f-638c-4515-af03-7c41ae60a42e2026-07-15Warnings, Adverse reactionsExact identifier
application applno (NDA): 215425
application number: NDA215425
EPINEPHRINEEPINEPHRINECIVICA, INC.4a79ad00-405b-4454-a692-7f1daac4adec2026-07-10Warnings, Adverse reactionsExact identifier
application applno (NDA): 215425
application number: NDA215425
ndc (product): 72572-238

Additional Listing Data#

Finished product
Yes
Brand name base
EPINEPHRINE
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
EPINEPHRINE1 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
YKH834O4BHInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
310132Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4a79ad00-405b-4454-a692-7f1daac4adecAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
0b4ec9ca-d305-43fc-88dd-7a510313efe0Product name120260105
bb209f42-a85f-4fee-9d3d-c9dded168625Product name120251208
49628fc7-2031-4c28-bd31-0ef3aa8f44a3Product name320251118
cbf85893-59ef-423f-87d4-a573c000a8b9Product name820250731
b5b1095b-40cd-8a9e-b111-502545045b07Product name420250325
e190029e-423b-473c-8e04-2ada59b5b711Product name120250314
e0031c74-3853-42bc-8e10-86dbbe83992eProduct name220231116
f7046b89-2016-499a-adc6-78479172abc6Product name120230425
2686d634-e712-4007-8dbf-3d37c6c4d71fProduct name120181121
fa8b5901-e681-426f-82fe-54f6d81ec698Product name420180619
bd49bb86-2d32-4a7a-a594-eeda2e29af42Product name120180118
c08ab52f-2fc8-4409-9d9f-ed8edc0bd070Product name120171221
3becbe78-12d9-4ad2-9b4c-1e36f8d1303aProduct name120170815

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
72572-238-01EPINEPHRINE30 mL in 1 VIAL, MULTI-DOSEINJECTION, SOLUTION, CONCENTRATE301
72572-238-01EPINEPHRINE1 in 1 CARTONINJECTION, SOLUTION, CONCENTRATE11

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
310132EPINEPHrine 1 MG/ML (1:1000) Injectable SolutionPSN4a79ad00-405b-4454-a692-7f1daac4adec1
310132epinephrine 1 MG/ML Injectable SolutionSCD4a79ad00-405b-4454-a692-7f1daac4adec1
310132epinephrine (as epinephrine hydrochloride) 1 MG/ML Injectable SolutionSY4a79ad00-405b-4454-a692-7f1daac4adec1
310132epinephrine 1:1000 Injectable SolutionSY4a79ad00-405b-4454-a692-7f1daac4adec1
310132epinephrine 500 MCG per 0.5 ML Injectable SolutionSY4a79ad00-405b-4454-a692-7f1daac4adec1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
72572-238-01725720238011 VIAL, MULTI-DOSE in 1 CARTON (72572-238-01) / 30 mL in 1 VIAL, MULTI-DOSE2025-03-13NoNoCurrent