Methylphenidate Hydrochloride

Product NDC
72603-399
Requested package NDC
72603-399-01
11-digit product format
726030399
Labeler code
72603
Product ID
72603-399_24936e25-28cd-53ce-e063-6294a90ad99d
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Methylphenidate Hydrochloride
Dosage form
TABLET, EXTENDED RELEASE
Route
ORAL
Labeler
Northstar Rx LLC
Application
ANDA217229
Marketing category
ANDA
Marketing start
2025-02-01
Substance
METHYLPHENIDATE HYDROCHLORIDE
Active strength
72 mg/1
Pharmacologic classes
Central Nervous System Stimulant [EPC], Central Nervous System Stimulation [PE]
DEA schedule
CII
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A217229-001METHYLPHENIDATE HYDROCHLORIDEMETHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-25

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A217229-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-258072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-256a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-251c564ffb4f44…
2023-12-20 04:57 UTC2023-12A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-25ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-25a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-259b2671bbb829…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217229-001METHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALAB2023-08-25a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A217229-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217229-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A217229-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217229-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217229-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217229-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217229-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A217229-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A217229-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A217229-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A217229-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A217229-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A217229-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A217229-001AB18072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A217229-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A217229-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A217229-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A217229-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A217229-001AB19b2671bbb829…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217229-001AB1a50c72e98297…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Methylphenidate HydrochlorideMETHYLPHENIDATE HYDROCHLORIDESun Pharmaceutical Industries, Inc.18024571-4505-6d51-e063-6294a90a19722026-04-24Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 217229
application number: ANDA217229
Methylphenidate HydrochlorideMETHYLPHENIDATE HYDROCHLORIDENorthstar Rx LLC768bf181-d0d8-49e5-9c87-cacbb069e0b22026-04-02Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 217229
application number: ANDA217229
ndc (package): 72603-399-01
ndc (product): 72603-399
ndc11 (package): 72603039901

Additional Listing Data#

Finished product
Yes
Brand name base
Methylphenidate Hydrochloride
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
METHYLPHENIDATE HYDROCHLORIDE72 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4B3SC438HIInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1995461Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
768bf181-d0d8-49e5-9c87-cacbb069e0b2Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
143536be-f21a-464c-bc5a-163f5c171815Product name220250626
fd4d0878-dcea-3832-288e-e3bbbbe580ffProduct name920240516
435f0341-cf24-41d5-8fbf-c909821e5596Product name120230313
c9b6eabb-08d7-bb2d-e81a-06be3590b436Product name220221216
67aa32c6-44f4-50de-64dd-643e8caf420dProduct name620210622
50b24f34-96fa-4f1e-b262-b0baf4a4a440Product name420210513
cf83c421-eebe-4de2-b1a2-fd96e3dbfcf8Product name120200128
166d1d2d-dd55-4fdf-82e2-b83a3c5347c1Product name120190828
343a61d5-785d-cc27-a43a-0779da054d88Product name320190828
7607489b-cd15-3103-f3b1-d4283574d250Product name220190614
407f0cce-da29-4050-a512-2cabe9e5692dProduct name920190611
f7f4bf1e-7c67-46c6-8c42-9beb1a06b38eProduct name220190415
190572d9-6c7b-4b40-8172-c1b5f802c20fProduct name120180724
2948856e-f76e-d380-d9ed-b317efafbc98Product name520180423
c0aa09de-7aa1-4a98-8f70-62ec3c97c695Product name120170803
3317aade-2d6e-f159-9fe6-e8385a825178Product name320160829
0fe52203-83a7-4fed-a91f-8e47a22cf1d3Product name120160111

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
72603-399-01Methylphenidate Hydrochloride30 in 1 BOTTLE, PLASTICTABLET, EXTENDED RELEASE301

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
72603-399-01EA - Each72603-39955a04d04-9390-4ec5-bf0e-48b2f31dafaf12025-01-14

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
72603-399METHYLPHENIDATE HYDROCHLORIDE TABLET, EXTENDED RELEASE [NORTHSTAR RX LLC]1Current NDC, 1 package rows20250201_768bf181-d0d8-49e5-9c87-cacbb069e0b2.zip

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
72603-399-017260303990130 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (72603-399-01) 2025-02-01NoNoCurrent