Theophylline

Product NDC
72789-441
11-digit product format
727890441
Labeler code
72789
Product ID
72789-441_4d7b0b3d-58b1-47ad-e063-6294a90a89e4
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Theophylline
Dosage form
TABLET, EXTENDED RELEASE
Route
ORAL
Labeler
PD-Rx Pharmaceuticals, Inc.
Application
ANDA215312
Marketing category
ANDA
Marketing start
2024-09-27
Substance
THEOPHYLLINE ANHYDROUS
Active strength
300 mg/1
Pharmacologic classes
Methylxanthine [EPC], Xanthines [CS]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A215312-001THEOPHYLLINETHEOPHYLLINE300MGTABLET, EXTENDED RELEASE / ORALAB2024-09-05
A215312-002THEOPHYLLINETHEOPHYLLINE450MGTABLET, EXTENDED RELEASE / ORALAB2024-09-05

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A215312-001AB
A215312-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A215312-001THEOPHYLLINE300MGTABLET, EXTENDED RELEASE / ORALAB2024-09-05011fe1cb6892…
2026-02-19 14:30 UTC2026-02A215312-002THEOPHYLLINE450MGTABLET, EXTENDED RELEASE / ORALAB2024-09-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215312-001THEOPHYLLINE300MGTABLET, EXTENDED RELEASE / ORALAB2024-09-0531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215312-002THEOPHYLLINE450MGTABLET, EXTENDED RELEASE / ORALAB2024-09-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08A215312-001THEOPHYLLINE300MGTABLET, EXTENDED RELEASE / ORALAB2024-09-056a471c1ec25d…
2025-08-23 18:47 UTC2025-08A215312-002THEOPHYLLINE450MGTABLET, EXTENDED RELEASE / ORALAB2024-09-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215312-001THEOPHYLLINE300MGTABLET, EXTENDED RELEASE / ORALAB2024-09-05fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215312-002THEOPHYLLINE450MGTABLET, EXTENDED RELEASE / ORALAB2024-09-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215312-001THEOPHYLLINE300MGTABLET, EXTENDED RELEASE / ORALAB2024-09-05b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215312-002THEOPHYLLINE450MGTABLET, EXTENDED RELEASE / ORALAB2024-09-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215312-001THEOPHYLLINE300MGTABLET, EXTENDED RELEASE / ORALAB2024-09-0503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215312-002THEOPHYLLINE450MGTABLET, EXTENDED RELEASE / ORALAB2024-09-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215312-001THEOPHYLLINE300MGTABLET, EXTENDED RELEASE / ORALAB2024-09-052680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215312-002THEOPHYLLINE450MGTABLET, EXTENDED RELEASE / ORALAB2024-09-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A215312-001THEOPHYLLINE300MGTABLET, EXTENDED RELEASE / ORALAB2024-09-055bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A215312-002THEOPHYLLINE450MGTABLET, EXTENDED RELEASE / ORALAB2024-09-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215312-001THEOPHYLLINE300MGTABLET, EXTENDED RELEASE / ORALAB2024-09-05d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215312-002THEOPHYLLINE450MGTABLET, EXTENDED RELEASE / ORALAB2024-09-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A215312-001THEOPHYLLINE300MGTABLET, EXTENDED RELEASE / ORALAB2024-09-05d06236e962d9…
2024-10-29 15:01 UTC2024-10A215312-002THEOPHYLLINE450MGTABLET, EXTENDED RELEASE / ORALAB2024-09-05d06236e962d9…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A215312-001THEOPHYLLINE300MGTABLET, EXTENDED RELEASE / ORALAB2024-09-05a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A215312-002THEOPHYLLINE450MGTABLET, EXTENDED RELEASE / ORALAB2024-09-05a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A215312-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A215312-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215312-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215312-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A215312-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A215312-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215312-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215312-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215312-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215312-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215312-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215312-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215312-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215312-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A215312-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A215312-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215312-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215312-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A215312-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A215312-002AB1d06236e962d9…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A215312-001AB1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A215312-002AB1a50c72e98297…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A215312-001CGT2025-03-2631067a03dcf5…
2025-08-23 18:47 UTC2025-08A215312-001CGT2025-03-266a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A215312-001CGT2025-03-26fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A215312-001CGT2025-03-26b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A215312-001CGT2025-03-2603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A215312-001CGT2025-03-262680178bc6a6…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A215312-001CGT2025-03-26d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A215312-001CGT2025-03-26d06236e962d9…

Additional Listing Data#

Finished product
Yes
Brand name base
Theophylline
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
THEOPHYLLINE ANHYDROUS300 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
0I55128JYKInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
317769Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
c6ca5cc9-4e5e-40cf-a36e-227aa4cb55c6Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
d1d07c79-5983-427d-b6f5-df0550dcc598Product name420250325
7b1e3dc0-e6b1-4d5d-943b-99fdd948b5a2Product name120170302

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
72789-441-01Theophylline100 in 1 BOTTLE, PLASTICTABLET, EXTENDED RELEASE1006

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
72789-441-01EA - Each72789-441a0400d05-d046-4d45-847a-9637ca7d18b712024-11-05

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
72789-441THEOPHYLLINE TABLET, EXTENDED RELEASE [PD-RX PHARMACEUTICALS, INC.]4Current NDC, 1 package rows20241018_c6ca5cc9-4e5e-40cf-a36e-227aa4cb55c6.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TheophyllineTHEOPHYLLINEPD-Rx Pharmaceuticals, Inc.c6ca5cc9-4e5e-40cf-a36e-227aa4cb55c62026-07-29Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215312
application number: ANDA215312
ndc (product): 72789-441
TheophyllineTHEOPHYLLINEPD-Rx Pharmaceuticals, Inc.5e64036a-ee3e-42e7-9e59-881f88a4e2982026-07-29Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215312
application number: ANDA215312
TheophyllineTHEOPHYLLINEStrides Pharma Science Limitedb7a90ccf-9c32-40cc-9008-7e55b3da4dfd2026-03-10Warnings, Adverse reactionsExact identifier
application applno (ANDA): 215312
application number: ANDA215312

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
317769theophylline 300 MG Extended Release Oral TabletPSNc6ca5cc9-4e5e-40cf-a36e-227aa4cb55c66
317769theophylline 300 MG Extended Release Oral TabletSCDc6ca5cc9-4e5e-40cf-a36e-227aa4cb55c66

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
72789-441-0172789044101100 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (72789-441-01) 2024-10-16NoNoCurrent