TreeActiv Cystic Acne Spot Treatment

Product NDC: 72841-201
11-digit product format: 728410201
Labeler code: 72841
Product ID: 72841-201_f9116ba0-b9be-4c3c-be76-8b9a6427e739
Type: HUMAN OTC DRUG
Nonproprietary name: SULFUR
Dosage form: PASTE
Route: TOPICAL
Labeler: Leiluna LLC
Application: M006
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2020-05-07
Substance: SULFUR
Active strength: 30 mg/mL
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 26 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	72841-201-01	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	72841-201-01	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	72841-201-01	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	72841-201-01	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded product	product		`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	72841-201-01	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded product	product		`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	72841-201-01	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded product	product		`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	72841-201-01	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded product	product		`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	72841-201-01	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded product	product		`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	72841-201-01	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded product	product		`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	72841-201-01	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded product	product		`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	72841-201-01	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded product	product		`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	72841-201-01	`834df4deac94…`	`adcc014656a3…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded product	product		`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	72841-201-01	`1332a3947898…`	`d4bfe170f9cd…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: TreeActiv Cystic Acne Spot Treatment
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
SULFUR	30 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
70FD1KFU70	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
2636729	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
d1b81650-ccc4-49ed-9378-726b3a3a04c7	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
6bd95106-a412-1dad-b9cc-4cb74bfb27ce	Product name	2	20230315
290f523a-f9db-9774-b5a9-e1f908ac1782	Product name	1	20150828
c6b65c52-69c7-df49-550a-a50c137f6218	Product name	1	20140508

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
72841-201-01	2025-04-08	C162847	48780-1	1030e365-5ee6-111a-e063-dadaa90a10e2	TreeActiv Cystic Acne Spot Treatment
72841-201-01	2024-01-30	C162847	48780-1	1030e365-5ee6-111a-e063-dadaa90a10e2	TreeActiv Cystic Acne Spot Treatment

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
72841-201-01	TreeActiv Cystic Acne Spot Treatment	15 mL in 1 JAR	PASTE	15	4
72841-201-01	TreeActiv Cystic Acne Spot Treatment	1 in 1 BOX	PASTE	1	4
72841-201-02	TreeActiv Cystic Acne Spot Treatment	2 in 1 PACKAGE, COMBINATION	PASTE	2	4
72841-201-02	TreeActiv Cystic Acne Spot Treatment	1 in 1 BOX	PASTE	1	4

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
72841-201	TREEACTIV CYSTIC ACNE SPOT TREATMENT (SULFUR) PASTE [LEILUNA LLC]	2	Current NDC, Legacy NDC, 4 package rows	20250410_d1b81650-ccc4-49ed-9378-726b3a3a04c7.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 20 of 55 · 1,088 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Dermaharmony 10% Sulfur	SULFUR	D3 Development, Inc.	c78ead80-a8ee-0b52-e053-2a95a90ab880	2025-12-01	Warnings	Exact identifier application number: M006
Dermaharmony 10% Sulfur with Tea Tree Oil	SULFUR	D3 Development, Inc.	c79005d4-0c6f-75d0-e053-2995a90a8314	2025-12-01	Warnings	Exact identifier application number: M006
Resurfacing acne swipes	SALICYLIC ACID	Oars And Alps LLC	efe14f46-c947-aea4-e053-2a95a90aad5f	2025-12-01	Warnings	Exact identifier application number: M006
EradiKate ACNE TREATMENT	SULFUR	Rare Beauty Brands Inc	44ebacf3-52c1-4896-e063-6394a90ac447	2025-12-01	Warnings	Exact identifier application number: M006
EradiKate Daily Foaming Cleanser Acne Treatment	SULFUR	Rare Beauty Brands Inc.	44ebc725-796f-71e6-e063-6294a90a69a6	2025-12-01	Warnings	Exact identifier application number: M006
ERADIKATE ACNE MARK FADING	SALICYLIC ACID	Rare Beauty Brands Inc.	44ebe505-1ce8-88cf-e063-6394a90a4baf	2025-12-01	Warnings	Exact identifier application number: M006
Jane Seymour Natural Advantage AM SPF 15 All Day Moisture with AHAs	AVOBENZONE, HOMOSALATE, OCTISALATE, OCTOCRYLENE, AND OXYBENZONE	Guthy-Renker,LLC	76298090-e873-4307-8bdb-19cdab6d9ac2	2025-12-01	Warnings	Exact identifier application number: M006
Asepxia Baking Soda Acne Bar	SALICYLIC ACID	Genomma Lab USA	ded9fe59-9477-4425-8bbb-f9a49118f004	2025-12-01	Warnings	Exact identifier application number: M006
Blemish Buster Solution Acne Treatment	SULFUR	Guthy-Renker LLC	d2b9462d-7897-40a4-9022-eeb04e7d5adf	2025-12-01	Warnings	Exact identifier application number: M006
Anna Guanche MD Miracle Cream The Pimple Cream	SULFUR	Bella Cosmeceuticals, Inc.	b4562cf4-aae3-e9db-e053-2995a90a7210	2025-11-30	Warnings	Exact identifier application number: M006
Vanishing Skincare	VANISHING DRY SERUM MASK, PHASE 3	Vanish Skincare LLC	27f19c03-1a18-6c74-e063-6394a90a6e86	2025-11-28	Warnings	Exact identifier application number: M006
OUHOE CLEARFACE Overnight Acne	SALICYLIC ACID	Shantou Ouhoe Technology Co., Ltd.	2be1e888-e0a4-7db7-e063-6294a90a77d5	2025-11-27	Warnings	Exact identifier application number: M006
EELHOE Acne	SALICYLIC ACID	Shantou Eelhoe Daily Chemical Technology Co., Ltd.	2a88a374-64bc-02a3-e063-6294a90a333e	2025-11-27	Warnings	Exact identifier application number: M006
EELHOE Mole Reduce Essence	SALICYLIC ACID	Shantou Eelhoe Daily Chemical Technology Co., Ltd.	2f80ffc4-c945-71c9-e063-6394a90add8c	2025-11-27	Warnings	Exact identifier application number: M006
JAYSUING ACNE PATCHES	SALICYLIC ACID	Shantou Jaysuing Cleaning and Environmental Protection Technology Co., Ltd.	29fb7bcc-a630-1fba-e063-6294a90a65c1	2025-11-27	Warnings	Exact identifier application number: M006
Relief	COLLOIDAL OATMEAL 1%	Era Organics, Inc.	0ad58a99-e41a-a830-e063-6294a90af9cb	2025-11-27	Warnings	Exact identifier application number: M006
Superbalm	COLLOIDAL OATMEAL 1%	Era Organics, Inc.	f5298e5e-583d-d74c-e053-2995a90affb5	2025-11-27	Warnings	Exact identifier application number: M006
OGEE CLEARGANICS TARGETED BLEMISH TREATMENT	SALICYLIC ACID ACNE MEDICATION	Ogee Inc	162831d3-7e95-62f4-e063-6394a90aef7c	2025-11-26	Warnings	Exact identifier application number: M006
EELHOE Pimple Patches	SALICYLIC ACID	Shantou Ximonth Biotechnology Co., Ltd.	ffd4972a-f9bd-44a4-9d29-cd5722696805	2025-11-26	Warnings	Exact identifier application number: M006
OUHOE PIMPLE	SALICYLIC ACID	Shantou Woodsleep Biotechnology Co., Ltd.	2a374e1c-0d21-e16c-e063-6394a90ab487	2025-11-26	Warnings	Exact identifier application number: M006

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
70FD1KFU70	SULFUR	7704-34-9	SULFUR

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
2636729	sulfur 3 % Paste	PSN	d1b81650-ccc4-49ed-9378-726b3a3a04c7	4
2636729	sulfur 0.03 MG/MG Paste	SCD	d1b81650-ccc4-49ed-9378-726b3a3a04c7	4
2636729	sulfur 3 % Paste	SY	d1b81650-ccc4-49ed-9378-726b3a3a04c7	4

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
72841-201-01	72841020101	1 JAR in 1 BOX (72841-201-01) / 15 mL in 1 JAR	1 jar	2020-05-07	0000-00-00	No	No	Current
72841-201-02	72841020102	2 BOX in 1 PACKAGE, COMBINATION (72841-201-02) / 1 JAR in 1 BOX / 15 mL in 1 JAR	2 box	2020-05-07		No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
TreeActiv Cystic Acne Spot Treatment	Leiluna LLC \| Island Kinetics, Inc. d.b.a. CoValence Laboratories	2025-04-08	HUMAN OTC DRUG LABEL	4