Cyclosporine

Product NDC
73043-005
11-digit product format
730430005
Labeler code
73043
Product ID
73043-005_5135618a-f2f6-49bd-b0ea-636cb2adf84c
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
cyclosporine
Dosage form
EMULSION
Route
OPHTHALMIC
Labeler
Devatis Inc.
Application
ANDA209811
Marketing category
ANDA
Marketing start
2024-07-04
Substance
CYCLOSPORINE
Active strength
.5 mg/mL
Pharmacologic classes
Calcineurin Inhibitor Immunosuppressant [EPC], Calcineurin Inhibitors [MoA], Cytochrome P450 3A4 Inhibitors [MoA], P-Glycoprotein Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A209811-001CYCLOSPORINECYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-05-21

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A209811-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A209811-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-05-21011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A209811-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-05-2131067a03dcf5…
2025-08-23 18:47 UTC2025-08A209811-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-05-216a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A209811-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-05-21fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A209811-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-05-21b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A209811-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-05-2103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A209811-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-05-212680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A209811-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-05-215bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A209811-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-05-21d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A209811-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-05-21d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A209811-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-05-2179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A209811-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-05-21301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A209811-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-05-211e350fbaab3a…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A209811-001CYCLOSPORINE0.05%EMULSION / OPHTHALMICAB2024-05-21a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A209811-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A209811-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A209811-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A209811-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A209811-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A209811-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A209811-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A209811-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A209811-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A209811-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A209811-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A209811-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A209811-001AB11e350fbaab3a…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A209811-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Cyclosporine
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CYCLOSPORINE.5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
83HN0GTJ6DInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2572292Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
7bb2078d-17c2-4e6a-9f61-26c7ecbce945Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
1be408a0-e15a-4092-b35e-4e294e65196fProduct name320240216
b3fdee3e-0c46-442f-aad5-aa71941d5621Product name120231023
78fb0708-fce5-decd-6611-5a9fbe3e3decProduct name320230327
54840517-000d-4fcb-b976-a6ddd102faa0Product name120220120
a5ba3bd0-8411-4005-ac3b-a41d8ee0633aProduct name120181029
b1c0d609-8b97-06ee-2cd0-5652a4b1d019Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
73043-005-01Cyclosporine10 in 1 POUCHEMULSION102
73043-005-01Cyclosporine3 in 1 CARTONEMULSION32
73043-005-02Cyclosporine10 in 1 POUCHEMULSION102
73043-005-02Cyclosporine6 in 1 CARTONEMULSION62

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
73043-005-01EA - Each73043-0051eb8045a-d072-4ad2-8ac0-15050e36e52412024-08-12
73043-005-02EA - Each73043-0054dc27c67-ae57-4c6a-b3fe-ff857eef56a612024-08-12

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
73043-005CYCLOSPORINE EMULSION [DEVATIS INC.]2Current NDC, 4 package rows20250312_7bb2078d-17c2-4e6a-9f61-26c7ecbce945.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
CyclosporineCYCLOSPORINEDevatis Inc.7bb2078d-17c2-4e6a-9f61-26c7ecbce9452025-02-17Warnings, Adverse reactionsExact identifier
application applno (ANDA): 209811
application number: ANDA209811
ndc (product): 73043-005

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2572292cycloSPORINE 0.05 % in 0.4 ML Ophthalmic EmulsionPSN7bb2078d-17c2-4e6a-9f61-26c7ecbce9452
25722920.4 ML cyclosporine 0.5 MG/ML Ophthalmic SuspensionSCD7bb2078d-17c2-4e6a-9f61-26c7ecbce9452
2572292cyclosporine 0.05 % per 0.4 ML Ophthalmic EmulsionSY7bb2078d-17c2-4e6a-9f61-26c7ecbce9452
2572292cyclosporine 0.5 MG/ML per 0.4 ML Ophthalmic EmulsionSY7bb2078d-17c2-4e6a-9f61-26c7ecbce9452

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
73043-005-01730430005013 POUCH in 1 CARTON (73043-005-01) / 10 VIAL, SINGLE-USE in 1 POUCH / .4 mL in 1 VIAL, SINGLE-USE3 pouch2024-07-04NoNoCurrent
73043-005-02730430005026 POUCH in 1 CARTON (73043-005-02) / 10 VIAL, SINGLE-USE in 1 POUCH / .4 mL in 1 VIAL, SINGLE-USE6 pouch2024-07-04NoNoCurrent