UPNEEQ

Product NDC: 73687-062
Requested package NDC: 73687-062-45
11-digit product format: 736870062
Labeler code: 73687
Product ID: 73687-062_3825ad82-1aa8-44bd-ae39-07d7f8984287
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: Oxymetazoline hydrochloride ophthalmic
Dosage form: SOLUTION/ DROPS
Route: OPHTHALMIC
Labeler: RVL Pharmaceuticals, Inc.
Application: NDA212520
Marketing category: NDA
Marketing start: 2020-08-21
Substance: OXYMETAZOLINE HYDROCHLORIDE
Active strength: 1 mg/mL
Pharmacologic classes: Imidazolines [CS], Increased Sympathetic Activity [PE], Vasoconstriction [PE], Vasoconstrictor [EPC]
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	73687-062	73687-062-45	D	Discontinued by firm		2026-10-12

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 1 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Archive	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	73687-062	73687-062-45	D	Discontinued by firm		excluded / ndc_excluded.zip	`d630ba8d3edf…`	`732f749b63fb…`

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N212520-001	UPNEEQ	OXYMETAZOLINE HYDROCHLORIDE	0.1%	SOLUTION/DROPS / OPHTHALMIC		RLD, RS	2020-07-08

Orange Book patents#

Current patent rows page 1 of 1 · 14 matching rows.

Application-product, Patent, Expiration table
Application-product	Patent	Expiration	Use code	Coverage / status	Submission date
N212520-001	10912765	2031-08-26	U-2849		2021-02-10
N212520-001	8357714	2031-08-26	U-2849		2020-07-14
N212520-001	9867808	2031-08-26	U-2849		2020-07-14
N212520-001	10799481	2039-12-16	U-2849		2020-10-20
N212520-001	10814001	2039-12-16		Drug product	2020-11-02
N212520-001	10898573	2039-12-16		Drug product	2021-01-27
N212520-001	10940138	2039-12-16	U-2849		2021-03-10
N212520-001	11103482	2039-12-16		Drug product	2021-09-10
N212520-001	11311515	2039-12-16		Drug product	2022-05-03
N212520-001	11324722	2039-12-16	U-2849		2022-05-11
N212520-001	11541036	2039-12-16		Drug product	2023-01-05
N212520-001	11701343	2039-12-16	U-2849		2023-11-07
N212520-001	12605363	2039-12-16		Drug product	2026-05-07
N212520-001	12648930	2039-12-16	U-2849		2026-06-23

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	RLD / RS	Approval date	Source SHA-256
2026-09-14 22:38:34	2026-08	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`4b0b4de00fa7…`
2022-03-09 01:35 UTC	2022-03	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`c0c555d07b60…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`f41ea6bd6efb…`
2022-09-29 23:25 UTC	2022-09	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`e64feba35796…`
2022-07-09 03:26 UTC · 3 captures of this ZIP	2022-07	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`cb3db0bc1861…`
2026-07-26 02:55 UTC · 3 captures of this ZIP	2026-06	N212520-001	UPNEEQ	0.1%	SOLUTION/DROPS / OPHTHALMIC	RLD, RS	2020-07-08	`a50c72e98297…`

Observed Orange Book patent history#

Patent history page 1 of 11 · 415 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Patent	Expiration	Use code	Coverage / status	Submission date	Source SHA-256
2026-09-14 22:38:34	2026-08	N212520-001	10912765	2031-08-26	U-2849		2021-02-10	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N212520-001	8357714	2031-08-26	U-2849		2020-07-14	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N212520-001	9867808	2031-08-26	U-2849		2020-07-14	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N212520-001	10799481	2039-12-16	U-2849		2020-10-20	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N212520-001	10814001	2039-12-16		Drug product	2020-11-02	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N212520-001	10898573	2039-12-16		Drug product	2021-01-27	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N212520-001	10940138	2039-12-16	U-2849		2021-03-10	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N212520-001	11103482	2039-12-16		Drug product	2021-09-10	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N212520-001	11311515	2039-12-16		Drug product	2022-05-03	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N212520-001	11324722	2039-12-16	U-2849		2022-05-11	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N212520-001	11541036	2039-12-16		Drug product	2023-01-05	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N212520-001	11701343	2039-12-16	U-2849		2023-11-07	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N212520-001	12605363	2039-12-16		Drug product	2026-05-07	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N212520-001	12648930	2039-12-16	U-2849		2026-06-23	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	N212520-001	10912765	2031-08-26	U-2849		2021-02-10	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N212520-001	8357714	2031-08-26	U-2849		2020-07-14	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N212520-001	9867808	2031-08-26	U-2849		2020-07-14	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N212520-001	10799481	2039-12-16	U-2849		2020-10-20	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N212520-001	10814001	2039-12-16		Drug product	2020-11-02	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N212520-001	10898573	2039-12-16		Drug product	2021-01-27	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N212520-001	10940138	2039-12-16	U-2849		2021-03-10	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N212520-001	11103482	2039-12-16		Drug product	2021-09-10	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N212520-001	11311515	2039-12-16		Drug product	2022-05-03	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N212520-001	11324722	2039-12-16	U-2849		2022-05-11	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N212520-001	11541036	2039-12-16		Drug product	2023-01-05	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N212520-001	11701343	2039-12-16	U-2849		2023-11-07	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N212520-001	12605363	2039-12-16		Drug product	2026-05-07	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N212520-001	12648930	2039-12-16	U-2849		2026-06-23	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N212520-001	10912765	2031-08-26	U-2849		2021-02-10	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N212520-001	8357714	2031-08-26	U-2849		2020-07-14	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N212520-001	9867808	2031-08-26	U-2849		2020-07-14	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N212520-001	10799481	2039-12-16	U-2849		2020-10-20	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N212520-001	10814001	2039-12-16		Drug product	2020-11-02	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N212520-001	10898573	2039-12-16		Drug product	2021-01-27	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N212520-001	10940138	2039-12-16	U-2849		2021-03-10	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N212520-001	11103482	2039-12-16		Drug product	2021-09-10	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N212520-001	11311515	2039-12-16		Drug product	2022-05-03	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N212520-001	11324722	2039-12-16	U-2849		2022-05-11	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N212520-001	11541036	2039-12-16		Drug product	2023-01-05	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N212520-001	11701343	2039-12-16	U-2849		2023-11-07	`011fe1cb6892…`

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
Captured	Edition	Application-product	Exclusivity code	Expiration	Source SHA-256
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N212520-001	NP	2023-07-08	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N212520-001	NP	2023-07-08	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N212520-001	NP	2023-07-08	`4b0b4de00fa7…`
2022-03-09 01:35 UTC	2022-03	N212520-001	NP	2023-07-08	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N212520-001	NP	2023-07-08	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N212520-001	NP	2023-07-08	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N212520-001	NP	2023-07-08	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	N212520-001	NP	2023-07-08	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N212520-001	NP	2023-07-08	`c0c555d07b60…`
2023-12-20 04:57 UTC	2023-12	N212520-001	NP	2023-07-08	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	N212520-001	NP	2023-07-08	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	N212520-001	NP	2023-07-08	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	N212520-001	NP	2023-07-08	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	N212520-001	NP	2023-07-08	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	N212520-001	NP	2023-07-08	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	N212520-001	NP	2023-07-08	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	N212520-001	NP	2023-07-08	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	N212520-001	NP	2023-07-08	`f41ea6bd6efb…`
2022-09-29 23:25 UTC	2022-09	N212520-001	NP	2023-07-08	`e64feba35796…`
2022-07-09 03:26 UTC · 3 captures of this ZIP	2022-07	N212520-001	NP	2023-07-08	`cb3db0bc1861…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: UPNEEQ
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
OXYMETAZOLINE HYDROCHLORIDE	1 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
K89MJ0S5VY	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
2391749	Internal RxNorm lookup
2391754	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
cf6c9a1f-2367-46d2-99c3-c7d67ec6f519	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
9e37788c-b1bf-42ae-aac9-b60601606144	Product name	8	20260122
30b0ac6e-02aa-0e5c-0d8b-cffdf3a282b2	Product name	5	20250304
1527ac37-808d-43be-a63e-74e1258dbe46	Product name	9	20250219
bed0530e-f939-4541-956b-6928a2f6404f	Product name	1	20241008
cefa60e2-a5b5-493e-9c54-24735b7dc509	Product name	6	20240814
362d7abb-94e6-4c60-9a58-266894157713	Product name	1	20231023
9fcb7a91-de07-4f00-aabf-e4d6fda403d5	Product name	8	20230322
6bd95106-a412-1dad-b9cc-4cb74bfb27ce	Product name	2	20230315
9badc7be-250a-44ab-aa36-926af3f02679	Product name	1	20210527
e67be450-f8e4-4bc1-88bd-1259d379f55f	Product name	1	20210127
0ec3537a-6c9b-432a-896c-b9ea8723049a	Product name	9	20200701
444b3e50-f226-46ef-bfca-2e7035d140cd	Product name	1	20190611
816b97af-edc5-4060-aff1-b814bdbcad50	Product name	1	20190415
7cda52fc-125f-421c-8fea-bc1974370c49	Product name	2	20180703
7916de40-e296-41f0-b811-6d0df1a33e2c	Product name	9	20180627
cefa60e2-a5b5-493e-9c54-24735b7dc509	Product name	2	20171212
419aab54-5d5a-4146-9453-026d4a9991be	Product name	2	20170525
c53f3286-4062-4cf5-8355-399519c639a6	Product name	1	20170424
a993dfc5-f219-4460-bde6-30dd724d9ef0	Product name	1	20160818
d5e51f11-ad28-caa4-4b49-4143974782ad	Product name	1	20150831
290f523a-f9db-9774-b5a9-e1f908ac1782	Product name	1	20150828
0ca1d589-929b-4b33-bc5b-1d84abdafa6a	Product name	1	20150324
fc363c46-397b-4476-ac0f-70e43e8e4592	Product name	1	20150324
89dac932-b90a-4410-9ab1-84c53e57de25	Product name	1	20150316
5668b646-cd56-c3c7-bdea-3f6b1a8840db	Product name	1	20140508
810ab97e-f109-f41c-7c83-6a652a9cbf43	Product name	1	20140508
87711080-88eb-65c5-b2dd-bf99e700a372	Product name	1	20140508
8dbefedf-0a0d-a224-5a3c-66dc9e11c2dd	Product name	1	20140508
c6b65c52-69c7-df49-550a-a50c137f6218	Product name	1	20140508
ec2149b3-5c6d-5344-f757-c86411073075	Product name	1	20140508
ed912195-5da0-0f2f-6f4b-3ef17710cbe3	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
73687-062-25	UPNEEQ	15 in 1 CARTON	SOLUTION/ DROPS	15	29
73687-062-32	UPNEEQ	30 in 1 CARTON	SOLUTION/ DROPS	30	29
73687-062-34	UPNEEQ	30 in 1 CARTON	SOLUTION/ DROPS	30	29
73687-062-45	UPNEEQ	45 in 1 CARTON	SOLUTION/ DROPS	45	29
73687-062-68	UPNEEQ	5 in 1 CARTON	SOLUTION/ DROPS	5	29
73687-062-70	UPNEEQ	.3 mL in 1 AMPULE	SOLUTION/ DROPS	.3	29
73687-062-80	UPNEEQ	.3 mL in 1 AMPULE	SOLUTION/ DROPS	.3	29

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
73687-062-32	EA - Each	73687-062	7f823c2a-0818-4d4d-87ec-55b29cf14979	1	2020-09-14
73687-062-45	EA - Each	73687-062	4b5a94df-0df7-421d-830c-0c2751530f9b	1	2022-01-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
73687-062	UPNEEQ (OXYMETAZOLINE HYDROCHLORIDE OPHTHALMIC) SOLUTION/ DROPS [RVL PHARMACEUTICALS, INC.]	28	Current NDC, Legacy NDC, 7 package rows	20241027_cf6c9a1f-2367-46d2-99c3-c7d67ec6f519.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
UPNEEQ	OXYMETAZOLINE HYDROCHLORIDE OPHTHALMIC	RVL Pharmaceuticals, Inc.	cf6c9a1f-2367-46d2-99c3-c7d67ec6f519	2026-07-23	Warnings, Adverse reactions	Exact identifier application applno (NDA): 212520 application number: NDA212520 ndc (package): 73687-062-45 ndc (product): 73687-062 ndc11 (package): 73687006245

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
K89MJ0S5VY	OXYMETAZOLINE HYDROCHLORIDE	2315-02-8	OXYMETAZOLINE HYDROCHLORIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
2391749	oxymetazoline hydrochloride 0.1 % Ophthalmic Solution	PSN	cf6c9a1f-2367-46d2-99c3-c7d67ec6f519	29
2391754	Upneeq 0.1 % Ophthalmic Solution	PSN	cf6c9a1f-2367-46d2-99c3-c7d67ec6f519	29
2391754	oxymetazoline hydrochloride 1 MG/ML Ophthalmic Solution [Upneeq]	SBD	cf6c9a1f-2367-46d2-99c3-c7d67ec6f519	29
2391749	oxymetazoline hydrochloride 1 MG/ML Ophthalmic Solution	SCD	cf6c9a1f-2367-46d2-99c3-c7d67ec6f519	29
2391749	oxymetazoline hydrochloride 0.1 % Ophthalmic Solution	SY	cf6c9a1f-2367-46d2-99c3-c7d67ec6f519	29
2391754	Upneeq 0.1 % Ophthalmic Solution	SY	cf6c9a1f-2367-46d2-99c3-c7d67ec6f519	29
2391754	Upneeq 1 MG/ML Ophthalmic Solution	SY	cf6c9a1f-2367-46d2-99c3-c7d67ec6f519	29

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
73687-062-45	73687006245	45 AMPULE in 1 CARTON (73687-062-45) > .3 mL in 1 AMPULE (73687-062-70)	45 ampule	2020-09-01	0000-00-00	No	No	Current