iwilfin

Product NDC
78670-150
11-digit product format
786700150
Labeler code
78670
Product ID
78670-150_5b900700-64d3-4f68-834a-2a71f5216a46
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
EFLORNITHINE HYDROCHLORIDE
Dosage form
TABLET
Route
ORAL
Labeler
USWM, LLC
Application
NDA215500
Marketing category
NDA
Marketing start
2024-01-15
Substance
EFLORNITHINE HYDROCHLORIDE
Active strength
250 mg/1
Pharmacologic classes
Antiprotozoal [EPC], Decarboxylase Inhibitor [EPC], Decarboxylase Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N215500-001IWILFINEFLORNITHINE HYDROCHLORIDEEQ 192MG BASETABLET / ORALRLD, RS2023-12-13

Orange Book patents#

Current patent rows page 1 of 1 · 1 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N215500-001125826252036-02-12U-44442026-04-01

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 2 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N215500-001NP2026-12-13
N215500-001ODE-4622030-12-13

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-13caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-13011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-1331067a03dcf5…
2025-08-23 18:47 UTC2025-08N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-136a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-13fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-13b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-1303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-132680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-135bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-13d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-13d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-1379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-13301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-131e350fbaab3a…
2024-05-31 18:47 UTC2024-05N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-138072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-136a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-131c564ffb4f44…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N215500-001IWILFINEQ 192MG BASETABLET / ORALRLD, RS2023-12-13a50c72e98297…

Observed Orange Book patent history#

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-18 06:07:402026-07N215500-001125826252036-02-12U-44442026-04-01caaa826d4ba7…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N215500-001125826252036-02-12U-44442026-04-01a50c72e98297…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-08-18 06:07:402026-07N215500-001NP2026-12-13caaa826d4ba7…
2026-08-18 06:07:402026-07N215500-001ODE-4622030-12-13caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N215500-001NP2026-12-13011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215500-001ODE-4622030-12-13011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215500-001NP2026-12-1331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215500-001ODE-4622030-12-1331067a03dcf5…
2025-08-23 18:47 UTC2025-08N215500-001NP2026-12-136a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215500-001ODE-4622030-12-136a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215500-001NP2026-12-13fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215500-001ODE-4622030-12-13fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215500-001NP2026-12-13b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215500-001ODE-4622030-12-13b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215500-001NP2026-12-1303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215500-001ODE-4622030-12-1303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215500-001NP2026-12-132680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215500-001ODE-4622030-12-132680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215500-001NP2026-12-135bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215500-001ODE-4622030-12-135bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N215500-001NP2026-12-13d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N215500-001ODE-4622030-12-13d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N215500-001NP2026-12-13d06236e962d9…
2024-10-29 15:01 UTC2024-10N215500-001ODE-4622030-12-13d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N215500-001NP2026-12-1379d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N215500-001ODE-4622030-12-1379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N215500-001NP2026-12-13301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N215500-001ODE-4622030-12-13301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N215500-001NP2026-12-131e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N215500-001ODE-4622030-12-131e350fbaab3a…
2024-05-31 18:47 UTC2024-05N215500-001NP2026-12-138072bd15b7f6…
2024-05-31 18:47 UTC2024-05N215500-001ODE-4622030-12-138072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N215500-001ODE-4622030-12-136a51e52b5d6a…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N215500-001NP2026-12-13a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N215500-001ODE-4622030-12-13a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
iwilfin
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
EFLORNITHINE HYDROCHLORIDE250 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4NH22NDW9HInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2673199Internal RxNorm lookup
2673205Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
6716d8cc-66e6-4cee-935c-ccb85ed984f5Available on FDA.report

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
78670-150-01iwilfin100 in 1 BOTTLETABLET1007
78670-150-01iwilfin1 in 1 CARTONTABLET17

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
78670-150-01EA - Each78670-150ba608d09-bece-479f-840a-58d452695b8212024-01-04

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
78670-150IWILFIN (EFLORNITHINE HYDROCHLORIDE) TABLET [USWM, LLC]5Current NDC, 2 package rows20250326_6716d8cc-66e6-4cee-935c-ccb85ed984f5.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
iwilfinEFLORNITHINE HYDROCHLORIDEUSWM, LLC6716d8cc-66e6-4cee-935c-ccb85ed984f52026-03-26Warnings, Adverse reactionsExact identifier
application applno (NDA): 215500
application number: NDA215500
ndc (product): 78670-150

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2673199eflornithine 192 MG Oral TabletPSN6716d8cc-66e6-4cee-935c-ccb85ed984f57
2673205iwilfin 192 MG Oral TabletPSN6716d8cc-66e6-4cee-935c-ccb85ed984f57
2673205eflornithine 192 MG Oral Tablet [Iwilfin]SBD6716d8cc-66e6-4cee-935c-ccb85ed984f57
2673199eflornithine 192 MG Oral TabletSCD6716d8cc-66e6-4cee-935c-ccb85ed984f57
2673199eflornithine 192 MG (equivalent to eflornithine HCl 250 MG) Oral TabletSY6716d8cc-66e6-4cee-935c-ccb85ed984f57
2673205Iwilfin 192 MG (equivalent to eflornithine HCl 250 MG) Oral TabletSY6716d8cc-66e6-4cee-935c-ccb85ed984f57
2673205Iwilfin 192 MG Oral TabletSY6716d8cc-66e6-4cee-935c-ccb85ed984f57

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
78670-150-01786700150011 BOTTLE in 1 CARTON (78670-150-01) / 100 TABLET in 1 BOTTLE1 bottle2024-01-15NoNoCurrent