Diphenhydramine HCl Oral Solution

Product NDC
81033-029
11-digit product format
810330029
Labeler code
81033
Product ID
81033-029_2f871005-de4e-8b2a-e063-6394a90aa43a
Type
HUMAN OTC DRUG
Nonproprietary name
Diphenhydramine HCl Oral Solution
Dosage form
SOLUTION
Route
ORAL
Labeler
Kesin Pharma Corporation
Application
M012
Marketing category
OTC MONOGRAPH DRUG
Marketing start
2025-03-04
Substance
DIPHENHYDRAMINE HCL
Active strength
12.5 mg/5mL
Pharmacologic classes
Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Diphenhydramine HCl Oral SolutionDIPHENHYDRAMINE HCL ORAL SOLUTIONKesin Pharma Corporation2f871005-de4d-8b2a-e063-6394a90aa43a2025-03-04WarningsExact identifier

Warnings cross-check#

openFDA text is shown for search and cross-checking; DailyMed SPL is canonical.

warnings

Warnings Do not use with any other products containing diphenhydramine, even one used on skin to make a child sleepy Ask a doctor before use if the child has a breathing problem such as chronic bronchitis glaucoma Ask a doctor or pharmacist before use if the child is taking sedastives or tranquilizers When using this product marked drowsiness may occur sedatives and tranquilizers may increase drowsiness excitability may occur, especially in children Keep out of reach of children. Overdose In case of overdose, get medical help or contact a Poison Control Center right away.

Additional Listing Data#

Finished product
Yes
Brand name base
Diphenhydramine HCl Oral Solution
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
DIPHENHYDRAMINE HCL12.5 mg/5mL

Harmonized Identifiers#

Field, Values table
FieldValues
UniiTC2D6JAD40
Rxcui1049906

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
0e2e0f88-b076-afe1-4bdd-32bca4375becProduct name320250127
e2db08c6-133f-4f4f-afb4-e90a2418d6f6Product name120230320
ce6d5c06-3ae0-18a6-d5b3-8cd3cc0f8906Product name720210625
f52be47f-7aa7-46c0-b1fa-50c18dd50206Product name120201029
11ed6f83-cdd2-4637-8379-b1a1d3ae3cdeProduct name120181101
86c45a79-b9f0-4476-a27c-6e10db098497Product name120180125
d5e51f11-ad28-caa4-4b49-4143974782adProduct name120150831
3e48c9c4-918d-5d23-2f0b-d2398b06be54Product name120140508
6084a4f4-5437-c9a5-caec-5361ee075a59Product name120140508
865c72dd-0d94-daac-f728-ddd4ded2a79eProduct name120140508
90c5639a-61b0-88d6-ddcf-21888e94869aProduct name120140508
9514609b-a2a9-f8ec-6ba6-3f8e5ee89877Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
81033-029-16Diphenhydramine HCl Oral Solution473 mL in 1 BOTTLESOLUTION4731

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
81033-029-16ML - Milliliter81033-0290dee0597-809d-41ba-9657-ec543028e40412025-06-13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
81033-029DIPHENHYDRAMINE HCL ORAL SOLUTION SOLUTION [KESIN PHARMA CORPORATION]1Current NDC, 1 package rows20250330_2f871005-de4d-8b2a-e063-6394a90aa43a.zip

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1049906diphenhydrAMINE HCl 12.5 MG in 5 mL Oral SolutionPSN2f871005-de4d-8b2a-e063-6394a90aa43a1
1049906diphenhydramine hydrochloride 2.5 MG/ML Oral SolutionSCD2f871005-de4d-8b2a-e063-6394a90aa43a1
1049906diphenhydramine HCl 12.5 MG per 5 ML Oral SolutionSY2f871005-de4d-8b2a-e063-6394a90aa43a1
1049906diphenhydramine hydrochloride 25 MG per 10 ML Oral SolutionSY2f871005-de4d-8b2a-e063-6394a90aa43a1
1049906diphenhydramine hydrochloride 50 MG per 20 ML Oral SolutionSY2f871005-de4d-8b2a-e063-6394a90aa43a1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
81033-029-1681033002916473 mL in 1 BOTTLE (81033-029-16) 473 ml2025-03-04NoNoCurrent