PIPERACILLIN AND TAZOBACTAM

Product NDC
81284-153
11-digit product format
812840153
Labeler code
81284
Product ID
81284-153_5e55a3fe-170f-4509-a4dd-307a6b24fc71
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Piperacillin sodium and Tazobactam sodium
Dosage form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Route
INTRAVENOUS
Labeler
Provepharm Inc.
Application
ANDA207847
Marketing category
ANDA
Marketing start
2019-08-01
Substance
PIPERACILLIN SODIUM; TAZOBACTAM SODIUM
Active strength
4; .5 g/20mL; g/20mL
Pharmacologic classes
Penicillin-class Antibacterial [EPC], Penicillins [CS], beta Lactamase Inhibitor [EPC], beta Lactamase Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A207847-001PIPERACILLIN AND TAZOBACTAMPIPERACILLIN SODIUM; TAZOBACTAM SODIUMEQ 2GM BASE/VIAL;EQ 250MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13
A207847-002PIPERACILLIN AND TAZOBACTAMPIPERACILLIN SODIUM; TAZOBACTAM SODIUMEQ 3GM BASE/VIAL;EQ 375MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13
A207847-003PIPERACILLIN AND TAZOBACTAMPIPERACILLIN SODIUM; TAZOBACTAM SODIUMEQ 4GM BASE/VIAL;EQ 500MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
A207847-001AP
A207847-002AP
A207847-003AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 126 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A207847-001PIPERACILLIN AND TAZOBACTAMEQ 2GM BASE/VIAL;EQ 250MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13caaa826d4ba7…
2026-08-18 06:07:402026-07A207847-002PIPERACILLIN AND TAZOBACTAMEQ 3GM BASE/VIAL;EQ 375MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13caaa826d4ba7…
2026-08-18 06:07:402026-07A207847-003PIPERACILLIN AND TAZOBACTAMEQ 4GM BASE/VIAL;EQ 500MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A207847-001PIPERACILLIN AND TAZOBACTAMEQ 2GM BASE/VIAL;EQ 250MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13011fe1cb6892…
2026-02-19 14:30 UTC2026-02A207847-002PIPERACILLIN AND TAZOBACTAMEQ 3GM BASE/VIAL;EQ 375MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13011fe1cb6892…
2026-02-19 14:30 UTC2026-02A207847-003PIPERACILLIN AND TAZOBACTAMEQ 4GM BASE/VIAL;EQ 500MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207847-001PIPERACILLIN AND TAZOBACTAMEQ 2GM BASE/VIAL;EQ 250MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-1331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207847-002PIPERACILLIN AND TAZOBACTAMEQ 3GM BASE/VIAL;EQ 375MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-1331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207847-003PIPERACILLIN AND TAZOBACTAMEQ 4GM BASE/VIAL;EQ 500MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-1331067a03dcf5…
2025-08-23 18:47 UTC2025-08A207847-001PIPERACILLIN AND TAZOBACTAMEQ 2GM BASE/VIAL;EQ 250MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-136a471c1ec25d…
2025-08-23 18:47 UTC2025-08A207847-002PIPERACILLIN AND TAZOBACTAMEQ 3GM BASE/VIAL;EQ 375MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-136a471c1ec25d…
2025-08-23 18:47 UTC2025-08A207847-003PIPERACILLIN AND TAZOBACTAMEQ 4GM BASE/VIAL;EQ 500MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-136a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207847-001PIPERACILLIN AND TAZOBACTAMEQ 2GM BASE/VIAL;EQ 250MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207847-002PIPERACILLIN AND TAZOBACTAMEQ 3GM BASE/VIAL;EQ 375MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207847-003PIPERACILLIN AND TAZOBACTAMEQ 4GM BASE/VIAL;EQ 500MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207847-001PIPERACILLIN AND TAZOBACTAMEQ 2GM BASE/VIAL;EQ 250MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207847-002PIPERACILLIN AND TAZOBACTAMEQ 3GM BASE/VIAL;EQ 375MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207847-003PIPERACILLIN AND TAZOBACTAMEQ 4GM BASE/VIAL;EQ 500MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207847-001PIPERACILLIN AND TAZOBACTAMEQ 2GM BASE/VIAL;EQ 250MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-1303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207847-002PIPERACILLIN AND TAZOBACTAMEQ 3GM BASE/VIAL;EQ 375MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-1303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207847-003PIPERACILLIN AND TAZOBACTAMEQ 4GM BASE/VIAL;EQ 500MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-1303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207847-001PIPERACILLIN AND TAZOBACTAMEQ 2GM BASE/VIAL;EQ 250MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-132680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207847-002PIPERACILLIN AND TAZOBACTAMEQ 3GM BASE/VIAL;EQ 375MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-132680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207847-003PIPERACILLIN AND TAZOBACTAMEQ 4GM BASE/VIAL;EQ 500MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-132680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207847-001PIPERACILLIN AND TAZOBACTAMEQ 2GM BASE/VIAL;EQ 250MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-135bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207847-002PIPERACILLIN AND TAZOBACTAMEQ 3GM BASE/VIAL;EQ 375MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-135bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207847-003PIPERACILLIN AND TAZOBACTAMEQ 4GM BASE/VIAL;EQ 500MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-135bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207847-001PIPERACILLIN AND TAZOBACTAMEQ 2GM BASE/VIAL;EQ 250MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207847-002PIPERACILLIN AND TAZOBACTAMEQ 3GM BASE/VIAL;EQ 375MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207847-003PIPERACILLIN AND TAZOBACTAMEQ 4GM BASE/VIAL;EQ 500MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A207847-001PIPERACILLIN AND TAZOBACTAMEQ 2GM BASE/VIAL;EQ 250MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13d06236e962d9…
2024-10-29 15:01 UTC2024-10A207847-002PIPERACILLIN AND TAZOBACTAMEQ 3GM BASE/VIAL;EQ 375MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13d06236e962d9…
2024-10-29 15:01 UTC2024-10A207847-003PIPERACILLIN AND TAZOBACTAMEQ 4GM BASE/VIAL;EQ 500MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207847-001PIPERACILLIN AND TAZOBACTAMEQ 2GM BASE/VIAL;EQ 250MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-1379d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207847-002PIPERACILLIN AND TAZOBACTAMEQ 3GM BASE/VIAL;EQ 375MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-1379d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207847-003PIPERACILLIN AND TAZOBACTAMEQ 4GM BASE/VIAL;EQ 500MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-1379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207847-001PIPERACILLIN AND TAZOBACTAMEQ 2GM BASE/VIAL;EQ 250MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207847-002PIPERACILLIN AND TAZOBACTAMEQ 3GM BASE/VIAL;EQ 375MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207847-003PIPERACILLIN AND TAZOBACTAMEQ 4GM BASE/VIAL;EQ 500MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-13301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A207847-001PIPERACILLIN AND TAZOBACTAMEQ 2GM BASE/VIAL;EQ 250MG BASE/VIALINJECTABLE / INJECTIONAP2017-01-131e350fbaab3a…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 126 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A207847-001AP1caaa826d4ba7…
2026-08-18 06:07:402026-07A207847-002AP1caaa826d4ba7…
2026-08-18 06:07:402026-07A207847-003AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A207847-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A207847-002AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A207847-003AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207847-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207847-002AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207847-003AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A207847-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A207847-002AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A207847-003AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207847-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207847-002AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207847-003AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207847-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207847-002AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207847-003AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207847-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207847-002AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207847-003AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207847-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207847-002AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207847-003AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207847-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207847-002AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207847-003AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207847-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207847-002AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207847-003AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A207847-001AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A207847-002AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A207847-003AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207847-001AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207847-002AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207847-003AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207847-001AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207847-002AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207847-003AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A207847-001AP11e350fbaab3a…

Additional Listing Data#

Finished product
Yes
Brand name base
PIPERACILLIN AND TAZOBACTAM
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PIPERACILLIN SODIUM4 g/20mL
TAZOBACTAM SODIUM.5 g/20mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
M98T69Q7HPInternal UNII lookup
UXA545ABTTInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1659131Internal RxNorm lookup
1659137Internal RxNorm lookup
1659149Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
bc26ffd8-1a6e-4e16-91c1-ec67c928b3bfAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
5fa255cf-091e-4504-8ebf-eef4259776e8Product name120260112
a6bfe911-d09e-4049-bcde-a3213184a72cProduct name820240501
61877847-a958-4874-a7cf-2bbeff51a37bProduct name220180717
e0d9b1cf-1fe5-42a8-b30f-70b3a7bd8d22Product name120150316

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
81284-153-00PIPERACILLIN AND TAZOBACTAM20 mL in 1 VIAL, SINGLE-DOSEINJECTION, POWDER, LYOPHILIZED,206
81284-153-10PIPERACILLIN AND TAZOBACTAM10 in 1 CARTONINJECTION, POWDER, LYOPHILIZED,106

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
81284-153-00EA - Each81284-15307686992-b6de-432d-af76-dc4d3c36d6ab12022-08-04
81284-153-10EA - Each81284-1539e372004-9f4f-49c2-8ce2-27edbb8ff97412022-08-04

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
81284-153PIPERACILLIN AND TAZOBACTAM (PIPERACILLIN SODIUM AND TAZOBACTAM SODIUM) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [PROVEPHARM INC.]6Current NDC, Legacy NDC, 2 package rows20250305_bc26ffd8-1a6e-4e16-91c1-ec67c928b3bf.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
PIPERACILLIN AND TAZOBACTAMPIPERACILLIN SODIUM AND TAZOBACTAM SODIUMProvepharm Inc.bc26ffd8-1a6e-4e16-91c1-ec67c928b3bf2025-02-26Warnings, Adverse reactionsExact identifier
application applno (ANDA): 207847
application number: ANDA207847
ndc (product): 81284-153

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1659131piperacillin / tazobactam 2.25 GM InjectionPSNbc26ffd8-1a6e-4e16-91c1-ec67c928b3bf6
1659137piperacillin / tazobactam 3.375 GM InjectionPSNbc26ffd8-1a6e-4e16-91c1-ec67c928b3bf6
1659149piperacillin / tazobactam 4.5 GM InjectionPSNbc26ffd8-1a6e-4e16-91c1-ec67c928b3bf6
1659131piperacillin 2000 MG / tazobactam 250 MG InjectionSCDbc26ffd8-1a6e-4e16-91c1-ec67c928b3bf6
1659137piperacillin 3000 MG / tazobactam 375 MG InjectionSCDbc26ffd8-1a6e-4e16-91c1-ec67c928b3bf6
1659149piperacillin 4000 MG / tazobactam 500 MG InjectionSCDbc26ffd8-1a6e-4e16-91c1-ec67c928b3bf6
1659131piperacillin (as piperacillin sodium) 2000 MG / tazobactam (as tazobactam sodium) 250 MG InjectionSYbc26ffd8-1a6e-4e16-91c1-ec67c928b3bf6
1659137piperacillin (as piperacillin sodium) 3000 MG / tazobactam (as tazobactam sodium) 375 MG InjectionSYbc26ffd8-1a6e-4e16-91c1-ec67c928b3bf6
1659149piperacillin (as piperacillin sodium) 4000 MG / tazobactam (as tazobactam sodium) 500 MG InjectionSYbc26ffd8-1a6e-4e16-91c1-ec67c928b3bf6
1659131piperacillin / tazobactam 2.25 GM InjectionSYbc26ffd8-1a6e-4e16-91c1-ec67c928b3bf6
1659137piperacillin / tazobactam 3.375 GM InjectionSYbc26ffd8-1a6e-4e16-91c1-ec67c928b3bf6
1659149piperacillin / tazobactam 4.5 GM InjectionSYbc26ffd8-1a6e-4e16-91c1-ec67c928b3bf6

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
81284-153-008128401530020 mL in 1 VIAL, SINGLE-DOSE20 mlHistorical
81284-153-108128401531010 VIAL, SINGLE-DOSE in 1 CARTON (81284-153-10) / 20 mL in 1 VIAL, SINGLE-DOSE (81284-153-00) 2019-08-010000-00-00NoNoCurrent