ClorRelief

Product NDC: 82643-002
11-digit product format: 826430002
Labeler code: 82643
Product ID: 82643-002_526f9c82-d393-f544-e063-6394a90a29d9
Type: HUMAN OTC DRUG
Nonproprietary name: Chlorpheniramine Maleate
Dosage form: AEROSOL, SPRAY
Route: ORAL
Labeler: FERRER MEDICAL INNOVATIONS LLC
Application: M012
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2023-04-21
Substance: CHLORPHENIRAMINE MALEATE
Active strength: 5 mg/mL
Pharmacologic classes: Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC]
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 18 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Code	Status	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded product	product		I	Inactivated by FDA	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	82643-002-15	I	Inactivated by FDA	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded product	product		I	Inactivated by FDA	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	82643-002-15	I	Inactivated by FDA	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		I	Inactivated by FDA	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	82643-002-15	I	Inactivated by FDA	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		I	Inactivated by FDA	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	82643-002-15	I	Inactivated by FDA	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		I	Inactivated by FDA	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	82643-002-15	I	Inactivated by FDA	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		I	Inactivated by FDA	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	82643-002-15	I	Inactivated by FDA	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded product	product		U	Excluded because listing certification expired	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	82643-002-15	U	Excluded because listing certification expired	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded product	product		U	Excluded because listing certification expired	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	82643-002-15	U	Excluded because listing certification expired	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded product	product		U	Excluded because listing certification expired	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	82643-002-15	U	Excluded because listing certification expired	`0efc9e666f02…`	`f202fb6c5f17…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: ClorRelief
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
CHLORPHENIRAMINE MALEATE	5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
V1Q0O9OJ9Z	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
2610305	Internal RxNorm lookup
2610310	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
db729011-f72f-5911-e053-2a95a90a68bf	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
d17a97fa-387f-690e-d2be-0083ab044a03	Product name	3	20170725
0fdb98e2-b951-a1ce-5715-2b187ba500ef	Product name	4	20170718
c6fba691-a132-4ede-95c6-f8c6bd696636	Product name	1	20150902
c0200ab5-4954-454e-9676-30b741b245bd	Product name	1	20150730

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
82643-002-15	2025-01-30	C162847	48780-1	2cef2736-720d-d83d-e063-dadaa90ab31f	ClorRelief (Chlorpheniramine Maleate 0.5%) Antihistamine Oral Spray

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
82643-002-15	ClorRelief	15 mL in 1 BOTTLE, WITH APPLICATOR	AEROSOL, SPRAY	15		4
82643-002-15	ClorRelief	1 in 1 CARTON	AEROSOL, SPRAY	1		4

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
82643-002	CLORRELIEF (CHLORPHENIRAMINE MALEATE) AEROSOL, SPRAY [FERRER MEDICAL INNOVATIONS LLC]	3	Current NDC, Legacy NDC, 2 package rows	20230422_db729011-f72f-5911-e053-2a95a90a68bf.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 52 of 180 · 3,583 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Sinus and Headache Daytime	ACETAMINOPHEN, PHENYLEPHRINE HCL	DOLGENCORP, LLC	869e950c-5861-4840-aaad-b0342790d62b	2026-02-10	Warnings	Exact identifier application number: M012
CareOne Night TIme Cold and Flu	ACETAMINOPHEN, DEXTROMETHORPHAN HBR, DOXYLAMINE SUCCINATE	American Sales Company	d6b9fb27-3ef7-47ee-81f2-b9a3ccd6de25	2026-02-10	Warnings	Exact identifier application number: M012
Medique Cold Cough Product	ACETAMINOPHEN, DEXTROMETHORPHAN HBR, PHENYLEPHRINE HCL ,	Sportpharm LLC	d61df3a4-8ae2-46b1-b322-7f4e04cc1bf9	2026-02-09	Warnings	Exact identifier application number: M012
Sinus Congestion and Pain Daytime	ACETAMINOPHEN AND PHENYLEPHRINE HCL	United Natural Foods, Inc. dba UNFI	f3fc270a-92fc-46d5-b187-44e875c3abb9	2026-02-09	Warnings	Exact identifier application number: M012
Sinus Severe	ACETAMINOPHEN, GUAIFENESIN, PHENYLEPHRINE HCL	L.N.K. International, Inc.	d5c8b248-6d82-4eac-881c-0b9d0a0de8f1	2026-02-09	Warnings	Exact identifier application number: M012
DayTime/NiteTime Severe Cold and Flu Maximum Strength	ACETAMINOPHEN, DEXTROMETHORPHAN HBR, GUAIFENESIN, DOXYLAMINE SUCCINATE, PHENYLEPHRINE HCL	Meijer Distribution Inc	d07112dd-27df-46cc-b7c3-af8ba7601d06	2026-02-09	Warnings	Exact identifier application number: M012
TYLENOL Cold Plus Flu Multi-Symptom Liquid Gels Day Plus Night	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE AND DOXYLAMINE SUCCINATE	Kenvue Brands LLC	48f7933e-6582-638c-e063-6394a90abfe5	2026-02-06	Warnings	Exact identifier application number: M012
Chest Rub	CAMPHOR, EUCALYPTUS OIL, MENTHOL	Retail Business Services, LLC	4fb46860-2bf9-41a7-89eb-31c259c61107	2026-02-06	Warnings, Adverse reactions	Exact identifier application number: M012
pseudoephedrine hydrochloride	PSEUDOEPHEDRINE HCL	Sportpharm LLC	909dacfa-50d3-4bcf-b2df-5405427cfaad	2026-02-06	Warnings	Exact identifier application number: M012
Good Sense Nasal	OXYMETAZOLINE HYDROCHLORIDE	Sportpharm LLC	f91b7c1f-e074-4767-b9c8-dbf1937a6a0f	2026-02-06	Warnings	Exact identifier application number: M012
Severe Allergy And Sinus Headache Maximum Strength	ACETAMINOPHEN, DIPHENHYDRAMINE HCL, PHENYLEPHRINE HCL	CVS Pharmacy	b3c744b8-aa93-505d-f8cf-07995da4283d	2026-02-06	Warnings	Exact identifier application number: M012
NightTime Cold and Flu Multi Symptom	ACETAMINOPHEN DEXTROMETHORPHAN HYDROBROMIDE DOXYLAMINE SUCCINATE	WinCo Foods, LLC	911e6a51-c0f0-491a-b70c-00011ed5e35b	2026-02-06	Warnings	Exact identifier application number: M012
Severe Sinus Daytime, Non-Drowsy	ACETAMINOPHEN, GUAIFENESIN, PHENYLEPHRINE HCL	Walgreen Company	cc0dc951-5024-4517-9d38-a01699407e7e	2026-02-06	Warnings	Exact identifier application number: M012
Chest Rub	CAMPHOR, EUCALYPTUS OIL, MENTHOL	Pharmacy Value Alliance, LLC	d836c3e2-3b69-41f3-b166-21270550e8ab	2026-02-05	Warnings, Adverse reactions	Exact identifier application number: M012
Chest Rub	CAMPHOR, EUCALYPTUS OIL, MENTHOL	Publix Super Markets, Inc.	81b1d5bb-f813-4f79-9559-2494db33ad3c	2026-02-05	Warnings, Adverse reactions	Exact identifier application number: M012
Nasal	OXYMETAZOLINE HYDROCHLORIDE	Kroger Company	6499f854-2995-48cb-9c80-be6524b3db43	2026-02-05	Warnings	Exact identifier application number: M012
Cold and Flu plus Congestion Daytime	ACETAMINOPHEN, DEXTROMETHORPHAN HBR, GUAIFENESIN, PHENYLEPHRINE HCL	WALMART INC.	52a398eb-e593-458b-9c42-6f653ca391be	2026-02-04	Warnings	Exact identifier application number: M012
Chest Rub	CAMPHOR, EUCALYPTUS OIL, MENTHOL	Hy-Vee, Inc.	446de381-6685-748d-e063-6394a90a1b73	2026-02-04	Warnings, Adverse reactions	Exact identifier application number: M012
Severe Cold and Flu	ACETAMINOPHEN, DEXTROMETHORPHAN HBR, GUAIFENESIN, PHENYLEPHRINE HCL	CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED	85aadc86-d979-41a1-849a-e2ccc9014429	2026-02-04	Warnings	Exact identifier application number: M012
severe cold and flu	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, DOXYLAMINE SUCCINATE, PHENYLEPHRINE HYDROCHLORIDE	HyVee Inc	fa8c154c-56c6-47de-8e43-9e012b4be95f	2026-02-04	Warnings	Exact identifier application number: M012

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
V1Q0O9OJ9Z	CHLORPHENIRAMINE MALEATE	113-92-8	CHLORPHENIRAMINE MALEATE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
2610305	chlorpheniramine maleate 0.5 % Mucosal Spray	PSN	db729011-f72f-5911-e053-2a95a90a68bf	4
2610310	ClorRelief 0.5 % Mucosal Spray	PSN	db729011-f72f-5911-e053-2a95a90a68bf	4
2610310	chlorpheniramine maleate 5 MG/ML Mucosal Spray [Clorrelief]	SBD	db729011-f72f-5911-e053-2a95a90a68bf	4
2610305	chlorpheniramine maleate 5 MG/ML Mucosal Spray	SCD	db729011-f72f-5911-e053-2a95a90a68bf	4
2610305	chlorpheniramine maleate 0.5 % Mucosal Spray	SY	db729011-f72f-5911-e053-2a95a90a68bf	4
2610310	ClorRelief 0.5 % Mucosal Spray	SY	db729011-f72f-5911-e053-2a95a90a68bf	4
2610310	Clorrelief 5 MG/ML Mucosal Spray	SY	db729011-f72f-5911-e053-2a95a90a68bf	4

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
82643-002-01	82643000201	120 mL in 1 BOTTLE, SPRAY (82643-002-01)	120 ml	2022-09-01	0000-00-00	No	No	Current
82643-002-15	82643000215	1 BOTTLE, WITH APPLICATOR in 1 CARTON (82643-002-15) / 15 mL in 1 BOTTLE, WITH APPLICATOR		2023-04-24		No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
ClorRelief (Chlorpheniramine Maleate 0.5%) Antihistamine Oral Spray	FERRER MEDICAL INNOVATIONS LLC \| Xlear Inc.	2026-05-22	HUMAN OTC DRUG LABEL	4