Ethyol

Product NDC
83107-030
11-digit product format
831070030
Labeler code
83107
Product ID
83107-030_4c20479c-d75a-a0c7-e063-6394a90a9e59
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Amifostine
Dosage form
INJECTION
Route
INTRAVENOUS
Labeler
Legacy Pharma USA Inc.
Application
NDA020221
Marketing category
NDA
Marketing start
2026-03-16
Substance
AMIFOSTINE
Active strength
500 mg/10mL
Pharmacologic classes
Cytoprotective Agent [EPC], Free Radical Scavenging Activity [MoA]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N020221-001ETHYOLAMIFOSTINE500MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD, RS1995-12-08
N020221-002ETHYOLAMIFOSTINE375MG/VIALINJECTABLE / INJECTION1999-09-10

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-01 22:54:322026-06N020221-001ETHYOL500MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD, RS1995-12-08a50c72e98297…
2026-08-01 22:54:322026-06N020221-002ETHYOL375MG/VIALINJECTABLE / INJECTION1999-09-10a50c72e98297…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
EthyolAMIFOSTINELegacy Pharma USA Inc.a17563f2-d231-4385-bc94-0217be78b89d2026-03-03Warnings, Adverse reactionsExact identifier
application applno (NDA): 020221
application number: NDA020221
ndc (product): 83107-030

Additional Listing Data#

Finished product
Yes
Brand name base
Ethyol
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
AMIFOSTINE500 mg/10mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
M487QF2F4VInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
308096Internal RxNorm lookup
1803018Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
a17563f2-d231-4385-bc94-0217be78b89dAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
573ca244-25d5-4578-9706-f9625e934801Product name120170816

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
83107-030-01Ethyol10 mL in 1 VIAL, SINGLE-DOSEINJECTION102
83107-030-02Ethyol3 in 1 CARTONINJECTION32

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
308096amifostine 500 MG InjectionPSNa17563f2-d231-4385-bc94-0217be78b89d2
1803018Ethyol 500 MG InjectionPSNa17563f2-d231-4385-bc94-0217be78b89d2
1803018amifostine 500 MG Injection [Ethyol]SBDa17563f2-d231-4385-bc94-0217be78b89d2
308096amifostine 500 MG InjectionSCDa17563f2-d231-4385-bc94-0217be78b89d2
1803018Ethyol 500 MG InjectionSYa17563f2-d231-4385-bc94-0217be78b89d2

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
83107-030-018310700300110 mL in 1 VIAL, SINGLE-DOSE10 mlHistorical
83107-030-02831070030023 VIAL, SINGLE-DOSE in 1 CARTON (83107-030-02) / 10 mL in 1 VIAL, SINGLE-DOSE (83107-030-01) 2026-03-16NoNoCurrent