20 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]

RxCUI: 1010692
RxNorm name: 20 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]
Display name: XYLOCAINE WITH EPINEPHrine (Injectable)
Full name: 20 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]
Term type: SBD
Status: Active
Strength: 0.005-20 mg/ml
Dose form: Injection 20 ml
Route: Injectable
Updated: 2026-06-16 07:05:27

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 102010
Active start: 102010
Multiple ingredient: YES
Branded: YES

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
epinephrine bitartrate	5 MCG / 1 ML	epinephrine	epinephrine
lidocaine hydrochloride	20 MG / 1 ML	lidocaine	lidocaine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Injection	1649574

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
epinephrine	3992
lidocaine	6387

Source Vocabulary Codes#

Code type, Value, Category table
Code type	Value	Category
PRESCRIBABLE	Y	ATTRIBUTES
RXNAV_STR	Xylocaine 2 % / EPINEPHrine 1:200,000 per 20 ML Injection	NAMES
RxNorm Name	20 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]	NAMES
RxNorm Synonym	Xylocaine 2 % / EPINEPHrine 1:200,000 per 20 ML Injection	NAMES
TTY	SBD	ATTRIBUTES
SPL_SET_ID	ba082c2f-64f4-419d-9c88-74f203316e17	CODES
SPL_SET_ID	cfcc8a07-b40c-476d-9a21-83487318ac85	CODES
RxCUI	1010692	CODES
MMSL_CODE	MTH_RXN_BD14950	CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDC	Product NDC	Name	Labeler	Application
0404-9972-20	0404-9972	Xylocaine Lidocaine Hydrochloride and epinephrine	Henry Schein, Inc.	NDA006488
63323-489-21	63323-489	Xylocaine LIDOCAINE HYDROCHLORIDE,EPINEPHRINE BITARTRATE	Fresenius Kabi USA, LLC	NDA006488
63323-489-27	63323-489	Xylocaine LIDOCAINE HYDROCHLORIDE,EPINEPHRINE BITARTRATE	Fresenius Kabi USA, LLC	NDA006488

Drugs@FDA Applications#

Application, NDC, Name table
Application	NDC	Name	Marketing category	Labeler
NDA006488	0404-9972	Xylocaine Lidocaine Hydrochloride and epinephrine	NDA	Henry Schein, Inc.

RxNav Current And Historical NDCs#

NDC11, Source, Active table
NDC11	Source	Active
00404997220	rxnav_ndcs	yes
63323048902	rxnav_ndcs	yes
63323048903	rxnav_ndcs	yes
63323048921	rxnav_ndcs	yes
63323048927	rxnav_ndcs	yes
00186012201	rxnav_historical
00186012212	rxnav_historical
00186012213	rxnav_historical
00186012291	rxnav_historical
00186025002	rxnav_historical
50090332101	rxnav_historical
52584048927	rxnav_historical
55154956808	rxnav_historical
63323048910	rxnav_historical
63323048917	rxnav_historical
63323048920	rxnav_historical
63323048991	rxnav_historical

DailyMed RxNorm Mappings#

Set ID, RxNorm string, TTY table
Set ID	RxNorm string	TTY	SPL version	Label	Effective
ba082c2f-64f4-419d-9c88-74f203316e17	Xylocaine 2 % / EPINEPHrine 1:200,000 in 20 ML Injection	PSN	13	Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)	20210825
ba082c2f-64f4-419d-9c88-74f203316e17	Xylocaine 2 % / EPINEPHrine 1:200,000 per 20 ML Injection	SY	13	Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)	20210825
ba082c2f-64f4-419d-9c88-74f203316e17	20 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]	SBD	13	Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)	20210825
cfcc8a07-b40c-476d-9a21-83487318ac85	Xylocaine 2 % / EPINEPHrine 1:200,000 in 20 ML Injection	PSN	6	Xylocaine MPF 2% (lidocaine hcl and epinephrine 1:200,00) 20mg/ml 20mL single dose vial	20251107
cfcc8a07-b40c-476d-9a21-83487318ac85	Xylocaine 2 % / EPINEPHrine 1:200,000 per 20 ML Injection	SY	6	Xylocaine MPF 2% (lidocaine hcl and epinephrine 1:200,00) 20mg/ml 20mL single dose vial	20251107
cfcc8a07-b40c-476d-9a21-83487318ac85	20 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]	SBD	6	Xylocaine MPF 2% (lidocaine hcl and epinephrine 1:200,00) 20mg/ml 20mL single dose vial	20251107
307e29b4-bcc1-4393-ab72-0687843bd1e3	20 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]	SBD	2	Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)	20190925
307e29b4-bcc1-4393-ab72-0687843bd1e3	Xylocaine 2 % / EPINEPHrine 1:200,000 in 20 ML Injection	PSN	2	Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)	20190925
307e29b4-bcc1-4393-ab72-0687843bd1e3	Xylocaine 2 % / EPINEPHrine 1:200,000 per 20 ML Injection	SY	2	Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)	20190925

DailyMed Labels#

Set ID, Title, Manufacturer table
Set ID	Title	Manufacturer	Effective
cfcc8a07-b40c-476d-9a21-83487318ac85	Xylocaine MPF 2% (lidocaine hcl and epinephrine 1:200,00) 20mg/ml 20mL single dose vial	Henry Schein, Inc.	20251107
cfcc8a07-b40c-476d-9a21-83487318ac85	Xylocaine MPF 2% (lidocaine hcl and epinephrine 1:200,00) 20mg/ml 20mL single dose vial	Henry Schein, Inc.	20240515
ba082c2f-64f4-419d-9c88-74f203316e17	Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)	Fresenius Kabi USA, LLC \| Fresenius Kabi Austria	20210825
307e29b4-bcc1-4393-ab72-0687843bd1e3	Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)	A-S Medication Solutions	20190925

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	C01CA	Adrenergic and dopaminergic agents	ATC1-4		epinephrine
ATC	R03AA	Alpha- and beta-adrenoreceptor agonists	ATC1-4		epinephrine
ATC	N01BB	Amides	ATC1-4		lidocaine
ATC	S02DA	Analgesics and anesthetics	ATC1-4		lidocaine
ATC	D04AB	Anesthetics for topical use	ATC1-4		lidocaine
ATC	R02AD	Anesthetics, local	ATC1-4		lidocaine
ATC	C01BB	Antiarrhythmics, class Ib	ATC1-4		lidocaine
ATC	C05AD	Local anesthetics	ATC1-4		lidocaine
ATC	S01HA	Local anesthetics	ATC1-4		lidocaine
ATC	B02BC	Local hemostatics	ATC1-4		epinephrine
ATC	A01AD	Other agents for local oral treatment	ATC1-4		epinephrine
ATC	S01EA	Sympathomimetics in glaucoma therapy	ATC1-4		epinephrine
ATC	R01AA	Sympathomimetics, plain	ATC1-4		epinephrine
FDASPL	D002395	Catecholamines	CHEM	has_chemical_structure	epinephrine
FDASPL	N0000175552	alpha-Adrenergic Agonist	EPC	has_epc	epinephrine
FDASPL	N0000175682	Amide Local Anesthetic	EPC	has_epc	lidocaine
FDASPL	N0000175426	Antiarrhythmic	EPC	has_epc	lidocaine
FDASPL	N0000175555	beta-Adrenergic Agonist	EPC	has_epc	epinephrine
FDASPL	N0000175570	Catecholamine	EPC	has_epc	epinephrine
FDASPL	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	epinephrine
FDASPL	N0000000245	Adrenergic beta-Agonists	MOA	has_moa	epinephrine
FDASPL	N0000175976	Local Anesthesia	PE	has_pe	lidocaine
MEDRT	D004837	Epinephrine	CHEM	has_ingredient	epinephrine
MEDRT	D008012	Lidocaine	CHEM	has_ingredient	lidocaine hydrochloride
MEDRT	D008012	Lidocaine	CHEM	has_ingredient	lidocaine
MEDRT	D000219	Adams-Stokes Syndrome	DISEASE	ci_with	lidocaine hydrochloride
MEDRT	D000219	Adams-Stokes Syndrome	DISEASE	ci_with	lidocaine
MEDRT	D000402	Airway Obstruction	DISEASE	may_treat	epinephrine
MEDRT	D000707	Anaphylaxis	DISEASE	may_treat	epinephrine
MEDRT	D001145	Arrhythmias, Cardiac	DISEASE	ci_with	epinephrine
MEDRT	D001919	Bradycardia	DISEASE	may_treat	epinephrine
MEDRT	D001986	Bronchial Spasm	DISEASE	may_treat	epinephrine
MEDRT	D002056	Burns	DISEASE	may_treat	lidocaine
MEDRT	D002056	Burns	DISEASE	may_treat	lidocaine hydrochloride
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	epinephrine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	lidocaine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	lidocaine hydrochloride
MEDRT	D064420	Drug-Related Side Effects and Adverse Reactions	DISEASE	may_treat	lidocaine hydrochloride
MEDRT	D064420	Drug-Related Side Effects and Adverse Reactions	DISEASE	may_treat	lidocaine
MEDRT	D004935	Esophageal Diseases	DISEASE	may_treat	lidocaine
MEDRT	D004935	Esophageal Diseases	DISEASE	may_treat	lidocaine hydrochloride
MEDRT	D015812	Glaucoma, Angle-Closure	DISEASE	ci_with	epinephrine
MEDRT	D005902	Glaucoma, Open-Angle	DISEASE	may_treat	epinephrine
MEDRT	D006323	Heart Arrest	DISEASE	may_treat	epinephrine
MEDRT	D006327	Heart Block	DISEASE	may_treat	epinephrine
MEDRT	D006967	Hypersensitivity	DISEASE	ci_with	lidocaine hydrochloride
MEDRT	D006967	Hypersensitivity	DISEASE	ci_with	lidocaine
MEDRT	D007022	Hypotension	DISEASE	may_treat	epinephrine
MEDRT	D009059	Mouth Diseases	DISEASE	may_treat	lidocaine
MEDRT	D009059	Mouth Diseases	DISEASE	may_treat	lidocaine hydrochloride
MEDRT	D009203	Myocardial Infarction	DISEASE	may_treat	lidocaine hydrochloride
MEDRT	D010146	Pain	DISEASE	may_prevent	lidocaine
MEDRT	D010146	Pain	DISEASE	may_prevent	lidocaine hydrochloride
MEDRT	D010146	Pain	DISEASE	may_treat	lidocaine
MEDRT	D010146	Pain	DISEASE	may_treat	lidocaine hydrochloride
MEDRT	D012772	Shock, Septic	DISEASE	may_treat	epinephrine
MEDRT	D013614	Tachycardia, Paroxysmal	DISEASE	may_treat	lidocaine
MEDRT	D013614	Tachycardia, Paroxysmal	DISEASE	may_treat	lidocaine hydrochloride
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	may_treat	epinephrine
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	may_treat	lidocaine hydrochloride
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	may_treat	lidocaine
MEDRT	D018754	Ventricular Dysfunction	DISEASE	may_treat	lidocaine hydrochloride
MEDRT	D014693	Ventricular Fibrillation	DISEASE	may_treat	epinephrine
MEDRT	D014693	Ventricular Fibrillation	DISEASE	may_treat	lidocaine
MEDRT	D014693	Ventricular Fibrillation	DISEASE	may_treat	lidocaine hydrochloride
MEDRT	D018879	Ventricular Premature Complexes	DISEASE	may_treat	lidocaine hydrochloride
MEDRT	D018879	Ventricular Premature Complexes	DISEASE	may_treat	lidocaine
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	epinephrine
MEDRT	N0000009921	Adrenergic beta1-Agonists	MOA	has_moa	epinephrine
MEDRT	N0000009922	Adrenergic beta2-Agonists	MOA	has_moa	epinephrine
MEDRT	N0000000180	Sodium Channel Interactions	MOA	has_moa	lidocaine
MEDRT	N0000000180	Sodium Channel Interactions	MOA	has_moa	lidocaine hydrochloride
MEDRT	N0000008298	Arterial Vasoconstriction	PE	has_pe	epinephrine
MEDRT	N0000008322	Bronchodilation	PE	has_pe	epinephrine
MEDRT	N0000008330	Cardiac Rhythm Alteration	PE	has_pe	lidocaine
MEDRT	N0000008330	Cardiac Rhythm Alteration	PE	has_pe	lidocaine hydrochloride
MEDRT	N0000008472	Decreased Cardiac Muscle Organized Electrical Activity	PE	has_pe	lidocaine hydrochloride
MEDRT	N0000008472	Decreased Cardiac Muscle Organized Electrical Activity	PE	has_pe	lidocaine
MEDRT	N0000009944	Decreased Intraocular Aqueous Secretion	PE	has_pe	epinephrine
MEDRT	N0000008889	Decreased Sensory-Somatic Nervous System Organized Electrical Activity	PE	has_pe	lidocaine
MEDRT	N0000008889	Decreased Sensory-Somatic Nervous System Organized Electrical Activity	PE	has_pe	lidocaine hydrochloride
MEDRT	N0000009014	Decreased Uterine Smooth Muscle Contraction or Tone	PE	has_pe	epinephrine
MEDRT	N0000009070	Hemostasis Alteration	PE	has_pe	epinephrine
MEDRT	N0000178478	Increased Blood Pressure	PE	has_pe	epinephrine
MEDRT	N0000175976	Local Anesthesia	PE	has_pe	lidocaine hydrochloride
MEDRT	N0000175976	Local Anesthesia	PE	has_pe	lidocaine
MEDRT	N0000009808	Positive Chronotropy	PE	has_pe	epinephrine
MEDRT	N0000009809	Positive Inotropy	PE	has_pe	epinephrine
MEDRT	N0000009820	Pupillary Dilation	PE	has_pe	epinephrine

Group, Type, Concept table
Group	Type	Concept	Source
BN	BN	Xylocaine with Epinephrine	rxnav_allrelated
DF	DF	Injection	rxnav_allrelated
DFG	DFG	Injectable Product	rxnav_allrelated
IN	IN	epinephrine	rxnav_allrelated
IN	IN	lidocaine	rxnav_allrelated
MIN	MIN	epinephrine / lidocaine	rxnav_allrelated
PIN	PIN	lidocaine hydrochloride	rxnav_allrelated
SBD	SBD	20 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]	rxnav_allrelated
SBDC	SBDC	epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML [Xylocaine with Epinephrine]	rxnav_allrelated
SBDF	SBDF	epinephrine / lidocaine Injection [Xylocaine with Epinephrine]	rxnav_allrelated
SBDFP	SBDFP	epinephrine / lidocaine hydrochloride Injection [Xylocaine with Epinephrine]	rxnav_allrelated
SBDG	SBDG	Xylocaine with Epinephrine Injectable Product	rxnav_allrelated
SCD	SCD	20 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection	rxnav_allrelated
SCDC	SCDC	epinephrine 0.005 MG/ML	rxnav_allrelated
SCDC	SCDC	lidocaine hydrochloride 20 MG/ML	rxnav_allrelated
SCDF	SCDF	epinephrine / lidocaine Injection	rxnav_allrelated
SCDFP	SCDFP	epinephrine / lidocaine hydrochloride Injection	rxnav_allrelated
SCDG	SCDG	epinephrine / lidocaine Injectable Product	rxnav_allrelated
SCDGP	SCDGP	epinephrine / lidocaine hydrochloride Injectable Product	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	0.005 MG/ML / 20 MG/ML
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	PRESCRIBABLE	Y
ATTRIBUTES	QUANTITY	20 ML
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
ATTRIBUTES	SCHEDULE	0
ATTRIBUTES	TTY	SBD
CODES	MMSL_CODE	MTH_RXN_BD14950
CODES	NDA	NDA006488
CODES	RxCUI	1010692
CODES	SPL_SET_ID	ba082c2f-64f4-419d-9c88-74f203316e17
CODES	SPL_SET_ID	cfcc8a07-b40c-476d-9a21-83487318ac85
NAMES	Prescribable Synonym	Xylocaine 2 % / EPINEPHrine 1:200,000 in 20 ML Injection
NAMES	RXNAV_STR	Xylocaine 2 % / EPINEPHrine 1:200,000 per 20 ML Injection
NAMES	RxNorm Name	20 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]
NAMES	RxNorm Synonym	Xylocaine 2 % / EPINEPHrine 1:200,000 per 20 ML Injection
NAMES	Tallman Synonym	20 ML EPINEPHrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with EPINEPHrine]
NAMES	Tallman Synonym	Xylocaine 2 % / EPINEPHrine 1:200,000 per 20 ML Injection
SOURCES	Source	Gold Standard Alchemy
SOURCES	Source	Metathesaurus FDA Structured Product Labels
SOURCES	Source	Micromedex RED BOOK
SOURCES	Source	Multum MediSource Lexicon

20 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]

RxNorm Status History#

Ingredients And Strength#

Dose Form Concepts#

Derived Ingredient Concepts#

Source Vocabulary Codes#

FDA NDC Products And Packages#

Drugs@FDA Applications#

RxNav Current And Historical NDCs#

DailyMed RxNorm Mappings#

DailyMed Labels#

Drug Classes#

Related Concepts#

Properties#