FDA.reportPublic FDA data

20 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]

RxCUI
1010692
RxNorm name
20 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]
Display name
XYLOCAINE WITH EPINEPHrine (Injectable)
Full name
20 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]
Term type
SBD
Status
Active
Strength
0.005-20 mg/ml
Dose form
Injection 20 ml
Route
Injectable
Updated
2026-06-16 07:05:27

RxNorm Status History#

Status
Active
Source
RXNORM
Current
YES
Release start
102010
Active start
102010
Multiple ingredient
YES
Branded
YES

Ingredients And Strength#

Ingredient, Strength, Base table
IngredientStrengthBaseBasis of strength
epinephrine bitartrate5 MCG / 1 MLepinephrineepinephrine
lidocaine hydrochloride20 MG / 1 MLlidocainelidocaine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose formRxCUI
Injection1649574

Derived Ingredient Concepts#

Ingredient, RxCUI table
IngredientRxCUI
epinephrine3992
lidocaine6387

Source Vocabulary Codes#

Code type, Value, Category table
Code typeValueCategory
PRESCRIBABLEYATTRIBUTES
RXNAV_STRXylocaine 2 % / EPINEPHrine 1:200,000 per 20 ML InjectionNAMES
RxNorm Name20 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]NAMES
RxNorm SynonymXylocaine 2 % / EPINEPHrine 1:200,000 per 20 ML InjectionNAMES
TTYSBDATTRIBUTES
SPL_SET_IDba082c2f-64f4-419d-9c88-74f203316e17CODES
SPL_SET_IDcfcc8a07-b40c-476d-9a21-83487318ac85CODES
RxCUI1010692CODES
MMSL_CODEMTH_RXN_BD14950CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDCProduct NDCNameLabelerApplication
0404-9972-200404-9972Xylocaine Lidocaine Hydrochloride and epinephrineHenry Schein, Inc.NDA006488
63323-489-2163323-489Xylocaine LIDOCAINE HYDROCHLORIDE,EPINEPHRINE BITARTRATEFresenius Kabi USA, LLCNDA006488
63323-489-2763323-489Xylocaine LIDOCAINE HYDROCHLORIDE,EPINEPHRINE BITARTRATEFresenius Kabi USA, LLCNDA006488

Drugs@FDA Applications#

Application, NDC, Name table
ApplicationNDCNameMarketing categoryLabeler
NDA0064880404-9972Xylocaine Lidocaine Hydrochloride and epinephrineNDAHenry Schein, Inc.

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 17 matching rows.

NDC11, Source, Active table
NDC11SourceActive
00404997220rxnav_ndcsyes
63323048902rxnav_ndcsyes
63323048903rxnav_ndcsyes
63323048921rxnav_ndcsyes
63323048927rxnav_ndcsyes
00186012201rxnav_historical
00186012212rxnav_historical
00186012213rxnav_historical
00186012291rxnav_historical
00186025002rxnav_historical
50090332101rxnav_historical
52584048927rxnav_historical
55154956808rxnav_historical
63323048910rxnav_historical
63323048917rxnav_historical
63323048920rxnav_historical
63323048991rxnav_historical

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
XylocaineLIDOCAINE HYDROCHLORIDE AND EPINEPHRINEHenry Schein, Inc.cfcc8a07-b40c-476d-9a21-83487318ac852025-11-07Warnings, Adverse reactionsExact identifier
ndc (package): 0404-9972-20
ndc (product): 0404-9972
ndc11 (package): 00404997220
rxcui: 1010692
XylocaineLIDOCAINE HYDROCHLORIDE,EPINEPHRINE BITARTRATEFresenius Kabi USA, LLCba082c2f-64f4-419d-9c88-74f203316e172021-08-25Warnings, Adverse reactionsExact identifier
ndc (package): 63323-489-21
ndc (package): 63323-489-27
ndc (product): 63323-489
ndc11 (package): 63323048927
ndc11 (package): 63323048921
ndc11 (package): 63323048903
ndc11 (package): 63323048917
ndc11 (package): 63323048902
rxcui: 1010692

DailyMed RxNorm Mappings#

Set ID, RxNorm string, TTY table
Set IDRxNorm stringTTYSPL versionLabelEffective
ba082c2f-64f4-419d-9c88-74f203316e17Xylocaine 2 % / EPINEPHrine 1:200,000 in 20 ML InjectionPSN13Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)20210825
ba082c2f-64f4-419d-9c88-74f203316e17Xylocaine 2 % / EPINEPHrine 1:200,000 per 20 ML InjectionSY13Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)20210825
ba082c2f-64f4-419d-9c88-74f203316e1720 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]SBD13Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)20210825
cfcc8a07-b40c-476d-9a21-83487318ac85Xylocaine 2 % / EPINEPHrine 1:200,000 in 20 ML InjectionPSN6Xylocaine MPF 2% (lidocaine hcl and epinephrine 1:200,00) 20mg/ml 20mL single dose vial20251107
cfcc8a07-b40c-476d-9a21-83487318ac85Xylocaine 2 % / EPINEPHrine 1:200,000 per 20 ML InjectionSY6Xylocaine MPF 2% (lidocaine hcl and epinephrine 1:200,00) 20mg/ml 20mL single dose vial20251107
cfcc8a07-b40c-476d-9a21-83487318ac8520 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]SBD6Xylocaine MPF 2% (lidocaine hcl and epinephrine 1:200,00) 20mg/ml 20mL single dose vial20251107
307e29b4-bcc1-4393-ab72-0687843bd1e320 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]SBD2Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)20190925
307e29b4-bcc1-4393-ab72-0687843bd1e3Xylocaine 2 % / EPINEPHrine 1:200,000 in 20 ML InjectionPSN2Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)20190925
307e29b4-bcc1-4393-ab72-0687843bd1e3Xylocaine 2 % / EPINEPHrine 1:200,000 per 20 ML InjectionSY2Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)20190925

DailyMed Labels#

Set ID, Title, Manufacturer table
Set IDTitleManufacturerEffective
cfcc8a07-b40c-476d-9a21-83487318ac85Xylocaine MPF 2% (lidocaine hcl and epinephrine 1:200,00) 20mg/ml 20mL single dose vialHenry Schein, Inc.20251107
cfcc8a07-b40c-476d-9a21-83487318ac85Xylocaine MPF 2% (lidocaine hcl and epinephrine 1:200,00) 20mg/ml 20mL single dose vialHenry Schein, Inc.20240515
c85e6c03-ca15-4c61-b023-22b0f50cbe9aXylocaine MPF 2% (lidocaine hcl and epinephrine 1:200,00) 20mg/ml 20mL single dose vialGeneral Injectables & Vaccines, Inc20221222
ba082c2f-64f4-419d-9c88-74f203316e17Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)Fresenius Kabi USA, LLC | Fresenius Kabi Austria20210825
307e29b4-bcc1-4393-ab72-0687843bd1e3Xylocaine® (lidocaine HCl Injection, USP) Xylocaine® (lidocaine HCl and epinephrine Injection, USP)A-S Medication Solutions20190925
95f92518-2250-473d-9707-87b61fdff9f1XylocaineCardinal Health20190909
5b1572d4-4c80-45fc-a17a-3064a75d4afdNational Council for Prescription Drug Programs20130213
d76e8470-1f6b-47c2-8725-33427c8c9068National Council for Prescription Drug Programs20130213
060d2a30-ef0f-4217-b6a1-2b9480814a95National Council for Prescription Drug Programs20120724
166479a5-291e-4225-b22f-086cf1193f69National Council for Prescription Drug Programs20120724
54ff07e7-5f48-4ea2-a418-1a939aa466c1National Council for Prescription Drug Programs20120724

Drug Classes#

Source, Class ID, Class table
SourceClass IDClassTypeRelationshipDrug concept
ATCC01CAAdrenergic and dopaminergic agentsATC1-4epinephrine
ATCR03AAAlpha- and beta-adrenoreceptor agonistsATC1-4epinephrine
ATCN01BBAmidesATC1-4lidocaine
ATCS02DAAnalgesics and anestheticsATC1-4lidocaine
ATCD04ABAnesthetics for topical useATC1-4lidocaine
ATCR02ADAnesthetics, localATC1-4lidocaine
ATCC01BBAntiarrhythmics, class IbATC1-4lidocaine
ATCC05ADLocal anestheticsATC1-4lidocaine
ATCS01HALocal anestheticsATC1-4lidocaine
ATCB02BCLocal hemostaticsATC1-4epinephrine
ATCA01ADOther agents for local oral treatmentATC1-4epinephrine
ATCS01EASympathomimetics in glaucoma therapyATC1-4epinephrine
ATCR01AASympathomimetics, plainATC1-4epinephrine
FDASPLD002395CatecholaminesCHEMhas_chemical_structureepinephrine
FDASPLN0000175552alpha-Adrenergic AgonistEPChas_epcepinephrine
FDASPLN0000175682Amide Local AnestheticEPChas_epclidocaine
FDASPLN0000175426AntiarrhythmicEPChas_epclidocaine
FDASPLN0000175555beta-Adrenergic AgonistEPChas_epcepinephrine
FDASPLN0000175570CatecholamineEPChas_epcepinephrine
FDASPLN0000000209Adrenergic alpha-AgonistsMOAhas_moaepinephrine
FDASPLN0000000245Adrenergic beta-AgonistsMOAhas_moaepinephrine
FDASPLN0000175976Local AnesthesiaPEhas_pelidocaine
MEDRTD004837EpinephrineCHEMhas_ingredientepinephrine
MEDRTD008012LidocaineCHEMhas_ingredientlidocaine hydrochloride
MEDRTD008012LidocaineCHEMhas_ingredientlidocaine
MEDRTD000219Adams-Stokes SyndromeDISEASEci_withlidocaine hydrochloride
MEDRTD000219Adams-Stokes SyndromeDISEASEci_withlidocaine
MEDRTD000402Airway ObstructionDISEASEmay_treatepinephrine
MEDRTD000707AnaphylaxisDISEASEmay_treatepinephrine
MEDRTD001145Arrhythmias, CardiacDISEASEci_withepinephrine
MEDRTD001919BradycardiaDISEASEmay_treatepinephrine
MEDRTD001986Bronchial SpasmDISEASEmay_treatepinephrine
MEDRTD002056BurnsDISEASEmay_treatlidocaine
MEDRTD002056BurnsDISEASEmay_treatlidocaine hydrochloride
MEDRTD004342Drug HypersensitivityDISEASEci_withepinephrine
MEDRTD004342Drug HypersensitivityDISEASEci_withlidocaine
MEDRTD004342Drug HypersensitivityDISEASEci_withlidocaine hydrochloride
MEDRTD064420Drug-Related Side Effects and Adverse ReactionsDISEASEmay_treatlidocaine hydrochloride
MEDRTD064420Drug-Related Side Effects and Adverse ReactionsDISEASEmay_treatlidocaine
MEDRTD004935Esophageal DiseasesDISEASEmay_treatlidocaine
MEDRTD004935Esophageal DiseasesDISEASEmay_treatlidocaine hydrochloride
MEDRTD015812Glaucoma, Angle-ClosureDISEASEci_withepinephrine
MEDRTD005902Glaucoma, Open-AngleDISEASEmay_treatepinephrine
MEDRTD006323Heart ArrestDISEASEmay_treatepinephrine
MEDRTD006327Heart BlockDISEASEmay_treatepinephrine
MEDRTD006967HypersensitivityDISEASEci_withlidocaine hydrochloride
MEDRTD006967HypersensitivityDISEASEci_withlidocaine
MEDRTD007022HypotensionDISEASEmay_treatepinephrine
MEDRTD009059Mouth DiseasesDISEASEmay_treatlidocaine
MEDRTD009059Mouth DiseasesDISEASEmay_treatlidocaine hydrochloride
MEDRTD009203Myocardial InfarctionDISEASEmay_treatlidocaine hydrochloride
MEDRTD010146PainDISEASEmay_preventlidocaine
MEDRTD010146PainDISEASEmay_preventlidocaine hydrochloride
MEDRTD010146PainDISEASEmay_treatlidocaine
MEDRTD010146PainDISEASEmay_treatlidocaine hydrochloride
MEDRTD012772Shock, SepticDISEASEmay_treatepinephrine
MEDRTD013614Tachycardia, ParoxysmalDISEASEmay_treatlidocaine
MEDRTD013614Tachycardia, ParoxysmalDISEASEmay_treatlidocaine hydrochloride
MEDRTD017180Tachycardia, VentricularDISEASEmay_treatepinephrine
MEDRTD017180Tachycardia, VentricularDISEASEmay_treatlidocaine hydrochloride
MEDRTD017180Tachycardia, VentricularDISEASEmay_treatlidocaine
MEDRTD018754Ventricular DysfunctionDISEASEmay_treatlidocaine hydrochloride
MEDRTD014693Ventricular FibrillationDISEASEmay_treatepinephrine
MEDRTD014693Ventricular FibrillationDISEASEmay_treatlidocaine
MEDRTD014693Ventricular FibrillationDISEASEmay_treatlidocaine hydrochloride
MEDRTD018879Ventricular Premature ComplexesDISEASEmay_treatlidocaine hydrochloride
MEDRTD018879Ventricular Premature ComplexesDISEASEmay_treatlidocaine
MEDRTN0000000209Adrenergic alpha-AgonistsMOAhas_moaepinephrine
MEDRTN0000009921Adrenergic beta1-AgonistsMOAhas_moaepinephrine
MEDRTN0000009922Adrenergic beta2-AgonistsMOAhas_moaepinephrine
MEDRTN0000000180Sodium Channel InteractionsMOAhas_moalidocaine
MEDRTN0000000180Sodium Channel InteractionsMOAhas_moalidocaine hydrochloride
MEDRTN0000008298Arterial VasoconstrictionPEhas_peepinephrine
MEDRTN0000008322BronchodilationPEhas_peepinephrine
MEDRTN0000008330Cardiac Rhythm AlterationPEhas_pelidocaine
MEDRTN0000008330Cardiac Rhythm AlterationPEhas_pelidocaine hydrochloride
MEDRTN0000008472Decreased Cardiac Muscle Organized Electrical ActivityPEhas_pelidocaine hydrochloride
MEDRTN0000008472Decreased Cardiac Muscle Organized Electrical ActivityPEhas_pelidocaine
MEDRTN0000009944Decreased Intraocular Aqueous SecretionPEhas_peepinephrine
MEDRTN0000008889Decreased Sensory-Somatic Nervous System Organized Electrical ActivityPEhas_pelidocaine
MEDRTN0000008889Decreased Sensory-Somatic Nervous System Organized Electrical ActivityPEhas_pelidocaine hydrochloride
MEDRTN0000009014Decreased Uterine Smooth Muscle Contraction or TonePEhas_peepinephrine
MEDRTN0000009070Hemostasis AlterationPEhas_peepinephrine
MEDRTN0000178478Increased Blood PressurePEhas_peepinephrine
MEDRTN0000175976Local AnesthesiaPEhas_pelidocaine hydrochloride
MEDRTN0000175976Local AnesthesiaPEhas_pelidocaine
MEDRTN0000009808Positive ChronotropyPEhas_peepinephrine
MEDRTN0000009809Positive InotropyPEhas_peepinephrine
MEDRTN0000009820Pupillary DilationPEhas_peepinephrine

Properties#

Category, Property, Value table
CategoryPropertyValue
ATTRIBUTESAVAILABLE_STRENGTH0.005 MG/ML / 20 MG/ML
ATTRIBUTESGENERAL_CARDINALITYMULTI
ATTRIBUTESHUMAN_DRUGUS
ATTRIBUTESPRESCRIBABLEY
ATTRIBUTESQUANTITY20 ML
ATTRIBUTESRXNAV_HUMAN_DRUGUS
ATTRIBUTESSCHEDULE0
ATTRIBUTESTTYSBD
CODESMMSL_CODEMTH_RXN_BD14950
CODESNDANDA006488
CODESRxCUI1010692
CODESSPL_SET_IDba082c2f-64f4-419d-9c88-74f203316e17
CODESSPL_SET_IDcfcc8a07-b40c-476d-9a21-83487318ac85
NAMESPrescribable SynonymXylocaine 2 % / EPINEPHrine 1:200,000 in 20 ML Injection
NAMESRXNAV_STRXylocaine 2 % / EPINEPHrine 1:200,000 per 20 ML Injection
NAMESRxNorm Name20 ML epinephrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with Epinephrine]
NAMESRxNorm SynonymXylocaine 2 % / EPINEPHrine 1:200,000 per 20 ML Injection
NAMESTallman Synonym20 ML EPINEPHrine 0.005 MG/ML / lidocaine hydrochloride 20 MG/ML Injection [Xylocaine with EPINEPHrine]
NAMESTallman SynonymXylocaine 2 % / EPINEPHrine 1:200,000 per 20 ML Injection
SOURCESSourceGold Standard Alchemy
SOURCESSourceMetathesaurus FDA Structured Product Labels
SOURCESSourceMicromedex RED BOOK
SOURCESSourceMultum MediSource Lexicon