FDA.reportPublic FDA data

naphazoline hydrochloride 0.5 MG/ML / phenylephrine hydrochloride 5 MG/ML / pyrilamine maleate 2 MG/ML Nasal Spray

RxCUI
1044286
RxNorm name
naphazoline hydrochloride 0.5 MG/ML / phenylephrine hydrochloride 5 MG/ML / pyrilamine maleate 2 MG/ML Nasal Spray
Term type
SCD
Status
Active
Updated
2026-06-13 07:08:44

RxNorm Status History#

Status
Active
Source
RXNORM
Current
YES
Release start
122010
Active start
122010
Multiple ingredient
YES
Branded
NO

Ingredients And Strength#

Ingredient, Strength, Base table
IngredientStrengthBaseBasis of strength
naphazoline hydrochloride0.5 MG / 1 MLnaphazolinenaphazoline hydrochloride
phenylephrine hydrochloride5 MG / 1 MLphenylephrinephenylephrine hydrochloride
pyrilamine maleate2 MG / 1 MLpyrilaminepyrilamine maleate

Dose Form Concepts#

Dose form, RxCUI table
Dose formRxCUI
Nasal Spray126542

Derived Ingredient Concepts#

Ingredient, RxCUI table
IngredientRxCUI
naphazoline7247
phenylephrine8163
pyrilamine9009

Source Vocabulary Codes#

Code type, Value, Category table
Code typeValueCategory
RXNAV_STRnaphazoline hydrochloride 0.5 MG/ML / phenylephrine hydrochloride 5 MG/ML / pyrilamine maleate 2 MG/ML Nasal SprayNAMES
RxNorm Namenaphazoline hydrochloride 0.5 MG/ML / phenylephrine hydrochloride 5 MG/ML / pyrilamine maleate 2 MG/ML Nasal SprayNAMES
TTYSCDATTRIBUTES
RxCUI1044286CODES
MMSL_CODEBD4972CODES
MMSL_CODECD4972CODES

RxNav Current And Historical NDCs#

NDC11, Source, Active table
NDC11SourceActive
19810000130rxnav_historical_indirect
19810005601rxnav_historical_indirect
19810005610rxnav_historical_indirect
19810005801rxnav_historical_indirect
19810005802rxnav_historical_indirect
19810005810rxnav_historical_indirect
19810005820rxnav_historical_indirect

Drug Classes#

Source, Class ID, Class table
SourceClass IDClassTypeRelationshipDrug concept
ATCC01CAAdrenergic and dopaminergic agentsATC1-4phenylephrine
ATCD04AAAntihistamines for topical useATC1-4pyrilamine
ATCC05AXOther agents for treatment of hemorrhoids and anal fissures for topical useATC1-4phenylephrine
ATCR06ACSubstituted ethylene diaminesATC1-4pyrilamine
ATCR01BASympathomimeticsATC1-4phenylephrine
ATCS01FBSympathomimetics excl. antiglaucoma preparationsATC1-4phenylephrine
ATCS01GASympathomimetics used as decongestantsATC1-4naphazoline
ATCS01GASympathomimetics used as decongestantsATC1-4phenylephrine
ATCR01ABSympathomimetics, combinations excl. corticosteroidsATC1-4naphazoline
ATCR01ABSympathomimetics, combinations excl. corticosteroidsATC1-4phenylephrine
ATCR01AASympathomimetics, plainATC1-4naphazoline
ATCR01AASympathomimetics, plainATC1-4phenylephrine
FDASPLN0000186105alpha-1 Adrenergic AgonistEPChas_epcphenylephrine
MEDRTD009278NaphazolineCHEMhas_ingredientnaphazoline
MEDRTD009278NaphazolineCHEMhas_ingredientnaphazoline hydrochloride
MEDRTD010656PhenylephrineCHEMhas_ingredientphenylephrine hydrochloride
MEDRTD010656PhenylephrineCHEMhas_ingredientphenylephrine
MEDRTD011738PyrilamineCHEMhas_ingredientpyrilamine maleate
MEDRTD011738PyrilamineCHEMhas_ingredientpyrilamine
MEDRTD013447SulfitesCHEMci_chemclassphenylephrine
MEDRTD013447SulfitesCHEMci_chemclassphenylephrine hydrochloride
MEDRTD003233Conjunctivitis, AllergicDISEASEmay_treatpyrilamine
MEDRTD003233Conjunctivitis, AllergicDISEASEmay_treatpyrilamine maleate
MEDRTD004342Drug HypersensitivityDISEASEci_withnaphazoline hydrochloride
MEDRTD004342Drug HypersensitivityDISEASEci_withpyrilamine maleate
MEDRTD004342Drug HypersensitivityDISEASEci_withnaphazoline
MEDRTD004342Drug HypersensitivityDISEASEci_withphenylephrine hydrochloride
MEDRTD004342Drug HypersensitivityDISEASEci_withphenylephrine
MEDRTD004342Drug HypersensitivityDISEASEci_withpyrilamine
MEDRTD005401Fissure in AnoDISEASEmay_treatphenylephrine hydrochloride
MEDRTD005401Fissure in AnoDISEASEmay_treatphenylephrine
MEDRTD015812Glaucoma, Angle-ClosureDISEASEci_withnaphazoline hydrochloride
MEDRTD015812Glaucoma, Angle-ClosureDISEASEci_withnaphazoline
MEDRTD005902Glaucoma, Open-AngleDISEASEmay_treatphenylephrine hydrochloride
MEDRTD005902Glaucoma, Open-AngleDISEASEmay_treatphenylephrine
MEDRTD006484HemorrhoidsDISEASEmay_treatphenylephrine hydrochloride
MEDRTD006484HemorrhoidsDISEASEmay_treatphenylephrine
MEDRTD006940HyperemiaDISEASEmay_treatnaphazoline
MEDRTD006940HyperemiaDISEASEmay_treatnaphazoline hydrochloride
MEDRTD006973HypertensionDISEASEci_withphenylephrine
MEDRTD006973HypertensionDISEASEci_withphenylephrine hydrochloride
MEDRTD007022HypotensionDISEASEmay_treatphenylephrine hydrochloride
MEDRTD007022HypotensionDISEASEmay_treatphenylephrine
MEDRTD015878MydriasisDISEASEinducesphenylephrine hydrochloride
MEDRTD015878MydriasisDISEASEinducesphenylephrine
MEDRTD011537PruritusDISEASEmay_treatpyrilamine
MEDRTD011537PruritusDISEASEmay_treatpyrilamine maleate
MEDRTD011538Pruritus AniDISEASEmay_treatphenylephrine hydrochloride
MEDRTD011538Pruritus AniDISEASEmay_treatphenylephrine
MEDRTD012220RhinitisDISEASEmay_treatnaphazoline
MEDRTD012220RhinitisDISEASEmay_treatnaphazoline hydrochloride
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatpyrilamine maleate
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatpyrilamine
MEDRTD006255Rhinitis, Allergic, SeasonalDISEASEmay_treatpyrilamine maleate
MEDRTD006255Rhinitis, Allergic, SeasonalDISEASEmay_treatpyrilamine
MEDRTD012223Rhinitis, VasomotorDISEASEmay_treatphenylephrine
MEDRTD012223Rhinitis, VasomotorDISEASEmay_treatphenylephrine hydrochloride
MEDRTD012772Shock, SepticDISEASEmay_treatphenylephrine
MEDRTD012772Shock, SepticDISEASEmay_treatphenylephrine hydrochloride
MEDRTD012852SinusitisDISEASEmay_treatnaphazoline
MEDRTD012852SinusitisDISEASEmay_treatnaphazoline hydrochloride
MEDRTD013617Tachycardia, SupraventricularDISEASEmay_treatphenylephrine
MEDRTD013617Tachycardia, SupraventricularDISEASEmay_treatphenylephrine hydrochloride
MEDRTD017180Tachycardia, VentricularDISEASEci_withphenylephrine
MEDRTD017180Tachycardia, VentricularDISEASEci_withphenylephrine hydrochloride
MEDRTN0000000209Adrenergic alpha-AgonistsMOAhas_moanaphazoline hydrochloride
MEDRTN0000000209Adrenergic alpha-AgonistsMOAhas_moaphenylephrine
MEDRTN0000000209Adrenergic alpha-AgonistsMOAhas_moaphenylephrine hydrochloride
MEDRTN0000000209Adrenergic alpha-AgonistsMOAhas_moanaphazoline
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moapyrilamine
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moapyrilamine maleate
MEDRTN0000008371Conjunctival Arterial VasoconstrictionPEhas_penaphazoline
MEDRTN0000008371Conjunctival Arterial VasoconstrictionPEhas_pephenylephrine
MEDRTN0000008371Conjunctival Arterial VasoconstrictionPEhas_penaphazoline hydrochloride
MEDRTN0000008371Conjunctival Arterial VasoconstrictionPEhas_pephenylephrine hydrochloride
MEDRTN0000008657Decreased Histamine ActivityPEhas_pepyrilamine maleate
MEDRTN0000008657Decreased Histamine ActivityPEhas_pepyrilamine
MEDRTN0000008896Decreased Nasal and Sinus SecretionsPEhas_penaphazoline
MEDRTN0000008896Decreased Nasal and Sinus SecretionsPEhas_pephenylephrine hydrochloride
MEDRTN0000008896Decreased Nasal and Sinus SecretionsPEhas_pephenylephrine
MEDRTN0000008896Decreased Nasal and Sinus SecretionsPEhas_penaphazoline hydrochloride

Properties#

Category, Property, Value table
CategoryPropertyValue
ATTRIBUTESAVAILABLE_STRENGTH0.5 MG/ML / 5 MG/ML / 2 MG/ML
ATTRIBUTESGENERAL_CARDINALITYMULTI
ATTRIBUTESHUMAN_DRUGUS
ATTRIBUTESRXNAV_HUMAN_DRUGUS
ATTRIBUTESTTYSCD
CODESMMSL_CODEBD4972
CODESMMSL_CODECD4972
CODESRxCUI1044286
NAMESPrescribable Synonymnaphazoline HCl 0.05 % / phenylephrine HCl 0.5 % / pyrilamine maleate 0.2 % Nasal Spray
NAMESRXNAV_STRnaphazoline hydrochloride 0.5 MG/ML / phenylephrine hydrochloride 5 MG/ML / pyrilamine maleate 2 MG/ML Nasal Spray
NAMESRxNorm Namenaphazoline hydrochloride 0.5 MG/ML / phenylephrine hydrochloride 5 MG/ML / pyrilamine maleate 2 MG/ML Nasal Spray
SOURCESSourceMicromedex RED BOOK