acetaminophen 20 MG/ML / hydrocodone bitartrate 0.667 MG/ML Oral Solution

RxCUI: 1044427
RxNorm name: acetaminophen 20 MG/ML / hydrocodone bitartrate 0.667 MG/ML Oral Solution
Display name: Acetaminophen/HYDROcodone (Oral Liquid)
Full name: acetaminophen 20 MG/ML / hydrocodone bitartrate 0.667 MG/ML Oral Solution
Term type: SCD
Status: Active
Strength: 300-10 mg/15ml
Dose form: Sol
Route: Oral Liquid
Updated: 2026-08-03 17:28:55

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 122010
Active start: 122010
Multiple ingredient: YES
Branded: NO

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
acetaminophen	20 MG / 1 ML	acetaminophen	acetaminophen
hydrocodone bitartrate	0.667 MG / 1 ML	hydrocodone	hydrocodone bitartrate

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Oral Solution	316968

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
acetaminophen	161
hydrocodone	5489

Source Vocabulary Codes#

Code type, Values, Count table
Code type	Values	Count	Category
PRESCRIBABLE	Y	1	ATTRIBUTES
RXNAV_STR	acetaminophen 20 MG/ML / HYDROcodone bitartrate 0.667 MG/ML Oral Solution	1	NAMES
RxNorm Name	acetaminophen 20 MG/ML / hydrocodone bitartrate 0.667 MG/ML Oral Solution	1	NAMES
RxNorm Synonym	2 linked values APAP 20 MG/ML / Hydrocodone Bitartrate 0.667 MG/ML Oral Solution APAP 300 MG / hydrocodone bitartrate 10 MG per 15 ML Oral Solution	2	NAMES
TTY	SCD	1	ATTRIBUTES
SPL_SET_ID	2 linked values 93b6dfdf-ba6e-4ea6-ab85-5ac121e33101 995a6cc7-8b72-4d35-b3b4-8c5752438fb7	2	CODES
RxCUI	1044427	1	CODES
MMSL_CODE	2 linked values BD26616 CD26616	2	CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDC	Product NDC	Name	Labeler	Application
0054-0843-63	0054-0843	HYDROCODONE BITARTRATE AND ACETAMINOPHEN HYDROCODONE BITARTRATE AND ACETAMINOPHEN	Hikma Pharmaceuticals USA Inc.	ANDA040881
27808-130-01	27808-130	hydrocodone bitartrate and acetaminophen hydrocodone bitartrate and acetaminophen	Cranbury Pharmaceuticals, LLC	ANDA201295

Drugs@FDA Applications#

Application, NDC, Name table
Application	NDC	Name	Marketing category	Labeler
ANDA040881	0054-0843	HYDROCODONE BITARTRATE AND ACETAMINOPHEN HYDROCODONE BITARTRATE AND ACETAMINOPHEN	ANDA	Hikma Pharmaceuticals USA Inc.
ANDA201295	27808-130	hydrocodone bitartrate and acetaminophen hydrocodone bitartrate and acetaminophen	ANDA	Cranbury Pharmaceuticals, LLC

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 3 matching rows.

NDC11, Source, Active table
NDC11	Source	Active
00054084363	rxnav_ndcs	yes
27808013001	rxnav_ndcs	yes
46672064516	rxnav_ndcs	yes

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
HYDROCODONE BITARTRATE AND ACETAMINOPHEN	HYDROCODONE BITARTRATE AND ACETAMINOPHEN	Hikma Pharmaceuticals USA Inc.	995a6cc7-8b72-4d35-b3b4-8c5752438fb7	2026-07-28	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 0054-0843-63 ndc (product): 0054-0843 ndc11 (package): 00054084363 rxcui: 1044427
hydrocodone bitartrate and acetaminophen	HYDROCODONE BITARTRATE AND ACETAMINOPHEN	Cranbury Pharmaceuticals, LLC	93b6dfdf-ba6e-4ea6-ab85-5ac121e33101	2026-01-08	Boxed warning, Warnings, Adverse reactions	Exact identifier ndc (package): 27808-130-01 ndc (product): 27808-130 ndc11 (package): 27808013001 rxcui: 1044427

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 3 matching rows.

Set ID, RxNorm mappings, Terms table
Set ID	RxNorm mappings	Terms	SPL version	Label	Effective
93b6dfdf-ba6e-4ea6-ab85-5ac121e33101	HYDROcodone bitartrate 10 MG / acetaminophen 300 MG in 15 mL Oral Solution [PSN] · acetaminophen 20 MG/ML / hydrocodone bitartrate 0.667 MG/ML Oral Solution [SCD] · APAP 20 MG/ML / Hydrocodone Bitartrate 0.667 MG/ML Oral Solution [SY] · APAP 300 MG / hydrocodone bitartrate 10 MG per 15 ML Oral Solution [SY]	4	23	Hydrocodone Bitartrate and Acetaminophen Oral Solution (CII) 10 mg/300 mg per 15 mL Rx Only	20260108
995a6cc7-8b72-4d35-b3b4-8c5752438fb7	HYDROcodone bitartrate 10 MG / acetaminophen 300 MG in 15 mL Oral Solution [PSN] · acetaminophen 20 MG/ML / hydrocodone bitartrate 0.667 MG/ML Oral Solution [SCD] · APAP 20 MG/ML / Hydrocodone Bitartrate 0.667 MG/ML Oral Solution [SY] · APAP 300 MG / hydrocodone bitartrate 10 MG per 15 ML Oral Solution [SY]	4	2	Hydrocodone Bitartrate and Acetaminophen Oral Solution, 10 mg/300 mg per 15 mL	20250122
34fddb2d-ccc5-4189-ac2a-146b46c447f6	HYDROcodone bitartrate 10 MG / acetaminophen 300 MG in 15 mL Oral Solution [PSN] · acetaminophen 20 MG/ML / hydrocodone bitartrate 0.667 MG/ML Oral Solution [SCD] · APAP 20 MG/ML / Hydrocodone Bitartrate 0.667 MG/ML Oral Solution [SY] · APAP 300 MG / hydrocodone bitartrate 10 MG per 15 ML Oral Solution [SY]	4	2		20160629

Recently Linked DailyMed Labels#

Set ID, Title, Manufacturer table
Set ID	Title	Manufacturer	Effective
995a6cc7-8b72-4d35-b3b4-8c5752438fb7	Hydrocodone Bitartrate and Acetaminophen Oral Solution, 10 mg/300 mg per 15 mL	Hikma Pharmaceuticals USA Inc.	20260728
995a6cc7-8b72-4d35-b3b4-8c5752438fb7	Hydrocodone Bitartrate and Acetaminophen Oral Solution, 10 mg/300 mg per 15 mL	Hikma Pharmaceuticals USA Inc.	20260423
93b6dfdf-ba6e-4ea6-ab85-5ac121e33101	Hydrocodone Bitartrate and Acetaminophen Oral Solution (CII) 10 mg/300 mg per 15 mL Rx Only	Cranbury Pharmaceuticals, LLC	20260108
995a6cc7-8b72-4d35-b3b4-8c5752438fb7	Hydrocodone Bitartrate and Acetaminophen Oral Solution, 10 mg/300 mg per 15 mL	Hikma Pharmaceuticals USA Inc.	20250122
7da90197-5801-4855-956e-a9373b3dec8c	Hydrocodone Bitartrate and Acetaminophen Oral Solution 10 mg/300 mg per 15 mL	Mikart, LLC	20201231

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	N02BE	Anilides	ATC1-4		acetaminophen
ATC	R05DA	Opium alkaloids and derivatives	ATC1-4		hydrocodone
FDASPL	N0000175690	Opioid Agonist	EPC	has_epc	hydrocodone
FDASPL	N0000000174	Opioid Agonists	MOA	has_moa	hydrocodone
MEDRT	D000082	Acetaminophen	CHEM	has_ingredient	acetaminophen
MEDRT	D006853	Hydrocodone	CHEM	has_ingredient	hydrocodone bitartrate
MEDRT	D006853	Hydrocodone	CHEM	has_ingredient	hydrocodone
MEDRT	D001249	Asthma	DISEASE	ci_with	hydrocodone bitartrate
MEDRT	D001249	Asthma	DISEASE	ci_with	hydrocodone
MEDRT	D003371	Cough	DISEASE	may_treat	hydrocodone bitartrate
MEDRT	D003371	Cough	DISEASE	may_treat	hydrocodone
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	hydrocodone bitartrate
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	hydrocodone
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	acetaminophen
MEDRT	D005334	Fever	DISEASE	may_prevent	acetaminophen
MEDRT	D005334	Fever	DISEASE	may_treat	acetaminophen
MEDRT	D005955	Glucosephosphate Dehydrogenase Deficiency	DISEASE	ci_with	acetaminophen
MEDRT	D007415	Intestinal Obstruction	DISEASE	ci_with	hydrocodone
MEDRT	D007415	Intestinal Obstruction	DISEASE	ci_with	hydrocodone bitartrate
MEDRT	D008107	Liver Diseases	DISEASE	ci_with	acetaminophen
MEDRT	D008173	Lung Diseases, Obstructive	DISEASE	may_treat	hydrocodone
MEDRT	D008173	Lung Diseases, Obstructive	DISEASE	may_treat	hydrocodone bitartrate
MEDRT	D010146	Pain	DISEASE	may_treat	acetaminophen
MEDRT	D010146	Pain	DISEASE	may_prevent	acetaminophen
MEDRT	D010149	Postoperative Pain	DISEASE	may_treat	hydrocodone
MEDRT	D010149	Postoperative Pain	DISEASE	may_treat	hydrocodone bitartrate
MEDRT	D012131	Respiratory Insufficiency	DISEASE	ci_with	hydrocodone
MEDRT	D012131	Respiratory Insufficiency	DISEASE	ci_with	hydrocodone bitartrate
MEDRT	N0000191866	Opioid mu-Receptor Agonists	MOA	has_moa	hydrocodone bitartrate
MEDRT	N0000191866	Opioid mu-Receptor Agonists	MOA	has_moa	hydrocodone
MEDRT	N0000000108	Prostaglandin Receptor Antagonists	MOA	has_moa	acetaminophen
MEDRT	N0000175439	Analgesia	PE	has_pe	hydrocodone
MEDRT	N0000175439	Analgesia	PE	has_pe	hydrocodone bitartrate
MEDRT	N0000175724	Central Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000008501	Decreased Central Nervous System Organized Electrical Activity	PE	ci_pe	hydrocodone bitartrate
MEDRT	N0000008501	Decreased Central Nervous System Organized Electrical Activity	PE	ci_pe	hydrocodone
MEDRT	N0000008701	Decreased Medullary Respiratory Drive	PE	has_pe	hydrocodone bitartrate
MEDRT	N0000008701	Decreased Medullary Respiratory Drive	PE	has_pe	hydrocodone
MEDRT	N0000008768	Decreased Organized Electrical Activity	PE	has_pe	hydrocodone
MEDRT	N0000008768	Decreased Organized Electrical Activity	PE	has_pe	hydrocodone bitartrate
MEDRT	N0000008836	Decreased Prostaglandin Production	PE	has_pe	acetaminophen
MEDRT	N0000009072	Hypothalamic Endocrine Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000175725	Peripheral Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000000026	Hepatic Metabolism	PK	has_pk	acetaminophen
MEDRT	N0000000042	Renal Excretion	PK	has_pk	acetaminophen

Group, Type, Concept table
Group	Type	Concept	Source
DF	DF	Oral Solution	rxnav_allrelated
DFG	DFG	Oral Liquid Product	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
IN	IN	acetaminophen	rxnav_allrelated
IN	IN	hydrocodone	rxnav_allrelated
MIN	MIN	acetaminophen / hydrocodone	rxnav_allrelated
PIN	PIN	hydrocodone bitartrate	rxnav_allrelated
SCD	SCD	acetaminophen 20 MG/ML / hydrocodone bitartrate 0.667 MG/ML Oral Solution	rxnav_allrelated
SCDC	SCDC	acetaminophen 20 MG/ML	rxnav_allrelated
SCDC	SCDC	hydrocodone bitartrate 0.667 MG/ML	rxnav_allrelated
SCDF	SCDF	acetaminophen / hydrocodone Oral Solution	rxnav_allrelated
SCDFP	SCDFP	acetaminophen / hydrocodone bitartrate Oral Solution	rxnav_allrelated
SCDG	SCDG	acetaminophen / hydrocodone Oral Liquid Product	rxnav_allrelated
SCDG	SCDG	acetaminophen / hydrocodone Oral Product	rxnav_allrelated
SCDGP	SCDGP	acetaminophen / hydrocodone bitartrate Oral Liquid Product	rxnav_allrelated
SCDGP	SCDGP	acetaminophen / hydrocodone bitartrate Oral Product	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	20 MG/ML / 0.667 MG/ML
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
ATTRIBUTES	SCHEDULE	2
CODES	ANDA	ANDA040881
CODES	ANDA	ANDA201295
CODES	VUID	4032836
CODES	VUID	4044022
NAMES	Prescribable Synonym	HYDROcodone bitartrate 10 MG / acetaminophen 300 MG in 15 mL Oral Solution
NAMES	Tallman Synonym	acetaminophen 20 MG/ML / HYDROcodone bitartrate 0.667 MG/ML Oral Solution
NAMES	Tallman Synonym	APAP 20 MG/ML / HYDROcodone Bitartrate 0.667 MG/ML Oral Solution
NAMES	Tallman Synonym	APAP 300 MG / HYDROcodone bitartrate 10 MG per 15 ML Oral Solution
SOURCES	Source	Gold Standard Alchemy
SOURCES	Source	Metathesaurus FDA Structured Product Labels
SOURCES	Source	Micromedex RED BOOK
SOURCES	Source	Multum MediSource Lexicon
SOURCES	Source	National Drug Data File Plus Source Vocabulary
SOURCES	Source	Veterans Health Administration National Drug File