Home RxNorm 1046384 acetaminophen 21.7 MG/ML / chlorpheniramine maleate 0.133 MG/ML / dextromethorphan hydrobromide 1 MG/ML Oral Solution Drug identity information. FDA.report links public drug records from RxNav, DailyMed, FDA NDC, Drugs@FDA, and related public sources where available. This page is informational only and is not medical, prescribing, or regulatory advice.
RxCUI 1046384
RxNorm name acetaminophen 21.7 MG/ML / chlorpheniramine maleate 0.133 MG/ML / dextromethorphan hydrobromide 1 MG/ML Oral Solution
Display name Acetaminophen/Chlorpheniramine/Dextromethorphan (Oral Liquid)
Full name acetaminophen 21.7 MG/ML / chlorpheniramine maleate 0.133 MG/ML / dextromethorphan hydrobromide 1 MG/ML Oral Solution
Term type SCD
Status Active
Strength 650-4.0-30 mg/30ml
Dose form Sol
Route Oral Liquid
Updated 2026-06-12 07:03:09 RxNorm Status History#
Status Active
Source RXNORM
Current YES
Release start 122010
Active start 122010
Multiple ingredient YES
Branded NO Ingredients And Strength# Derived Ingredient Concepts# FDA NDC Products And Packages# Package NDC, Product NDC, Name table Package NDC Product NDC Name Labeler Application 69423-899-12 69423-899 Vicks NyQuil Alcohol Free Acetaminophen, Chlorpheniramine maleate, and Dextromethorphan Hydrobromide The Procter & Gamble Manufacturing Company M012
Drugs@FDA Applications# Application, NDC, Name table Application NDC Name Marketing category Labeler M012 69423-899 Vicks NyQuil Alcohol Free Acetaminophen, Chlorpheniramine maleate, and Dextromethorphan Hydrobromide OTC MONOGRAPH DRUG The Procter & Gamble Manufacturing Company
RxNav Current And Historical NDCs# RxNav current and historical NDC rows page 1 of 1 · 7 matching rows.
NDC11, Source, Active table NDC11 Source Active 37000069912 rxnav_ndcs yes 69423089912 rxnav_ndcs yes 23900001434 rxnav_historical_indirect 37000069906 rxnav_historical 37000069908 rxnav_historical 37000069910 rxnav_historical 69842010002 rxnav_historical
UNII Substances# UNII substance links page 1 of 1 · 0 matching rows.
No records found.
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 1 of 1 · 1 matching rows.
DailyMed RxNorm Mappings# Set ID, RxNorm string, TTY table Set ID RxNorm string TTY SPL version Label Effective ec57c15e-cb6d-44a9-e053-2a95a90ae774 APAP 21.7 MG/ML / Chlorpheniramine Maleate 0.133 MG/ML / Dextromethorphan Hydrobromide 1 MG/ML Oral Solution SY 7 VICKS ® NyQuil Alcohol Free COLD & FLU 20251201 ec57c15e-cb6d-44a9-e053-2a95a90ae774 acetaminophen 650 MG / chlorpheniramine maleate 4 MG / dextromethorphan HBr 30 MG in 30 mL Oral Solution PSN 7 VICKS ® NyQuil Alcohol Free COLD & FLU 20251201 ec57c15e-cb6d-44a9-e053-2a95a90ae774 acetaminophen 21.7 MG/ML / chlorpheniramine maleate 0.133 MG/ML / dextromethorphan hydrobromide 1 MG/ML Oral Solution SCD 7 VICKS ® NyQuil Alcohol Free COLD & FLU 20251201 ec57c15e-cb6d-44a9-e053-2a95a90ae774 acetaminophen 650 MG / chlorpheniramine maleate 4 MG / dextromethorphan hydrobromide 30 MG per 30 ML Oral Solution SY 7 VICKS ® NyQuil Alcohol Free COLD & FLU 20251201 ec57c15e-cb6d-44a9-e053-2a95a90ae774 acetaminophen 325 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG per 15 ML Oral Solution SY 7 VICKS ® NyQuil Alcohol Free COLD & FLU 20251201
Drug Classes# Source, Class ID, Class table Source Class ID Class Type Relationship Drug concept ATC N02BE Anilides ATC1-4 acetaminophen ATC R05DA Opium alkaloids and derivatives ATC1-4 dextromethorphan ATC R06AB Substituted alkylamines ATC1-4 chlorpheniramine FDASPL N0000175587 Histamine-1 Receptor Antagonist EPC has_epc chlorpheniramine FDASPL N0000182149 Sigma-1 Agonist EPC has_epc dextromethorphan FDASPL N0000181821 Uncompetitive N-methyl-D-aspartate Receptor Antagonist EPC has_epc dextromethorphan FDASPL N0000182147 Sigma-1 Receptor Agonists MOA has_moa dextromethorphan FDASPL N0000181819 Uncompetitive NMDA Receptor Antagonists MOA has_moa dextromethorphan MEDRT D000082 Acetaminophen CHEM has_ingredient acetaminophen MEDRT D002744 Chlorpheniramine CHEM has_ingredient chlorpheniramine maleate MEDRT D002744 Chlorpheniramine CHEM has_ingredient chlorpheniramine MEDRT D003915 Dextromethorphan CHEM has_ingredient dextromethorphan hydrobromide MEDRT D003915 Dextromethorphan CHEM has_ingredient dextromethorphan MEDRT D003371 Cough DISEASE may_treat dextromethorphan hydrobromide MEDRT D003371 Cough DISEASE may_treat dextromethorphan MEDRT D003371 Cough DISEASE may_prevent dextromethorphan MEDRT D003371 Cough DISEASE may_prevent dextromethorphan hydrobromide MEDRT D004342 Drug Hypersensitivity DISEASE ci_with dextromethorphan hydrobromide MEDRT D004342 Drug Hypersensitivity DISEASE ci_with dextromethorphan MEDRT D004342 Drug Hypersensitivity DISEASE ci_with chlorpheniramine maleate MEDRT D004342 Drug Hypersensitivity DISEASE ci_with chlorpheniramine MEDRT D004342 Drug Hypersensitivity DISEASE ci_with acetaminophen MEDRT D004380 Duodenal Obstruction DISEASE ci_with chlorpheniramine MEDRT D004380 Duodenal Obstruction DISEASE ci_with chlorpheniramine maleate MEDRT D005334 Fever DISEASE may_prevent acetaminophen MEDRT D005334 Fever DISEASE may_treat acetaminophen MEDRT D015812 Glaucoma, Angle-Closure DISEASE ci_with chlorpheniramine maleate MEDRT D015812 Glaucoma, Angle-Closure DISEASE ci_with chlorpheniramine MEDRT D005955 Glucosephosphate Dehydrogenase Deficiency DISEASE ci_with acetaminophen MEDRT D007231 Infant, Newborn DISEASE ci_with chlorpheniramine MEDRT D007231 Infant, Newborn DISEASE ci_with chlorpheniramine maleate MEDRT D007234 Infant, Premature DISEASE ci_with chlorpheniramine MEDRT D007234 Infant, Premature DISEASE ci_with chlorpheniramine maleate MEDRT D008107 Liver Diseases DISEASE ci_with acetaminophen MEDRT D010146 Pain DISEASE may_prevent acetaminophen MEDRT D010146 Pain DISEASE may_treat acetaminophen MEDRT D010437 Peptic Ulcer DISEASE ci_with chlorpheniramine maleate MEDRT D010437 Peptic Ulcer DISEASE ci_with chlorpheniramine MEDRT D011470 Prostatic Hyperplasia DISEASE ci_with chlorpheniramine MEDRT D011470 Prostatic Hyperplasia DISEASE ci_with chlorpheniramine maleate MEDRT D012221 Rhinitis, Allergic, Perennial DISEASE may_treat chlorpheniramine maleate MEDRT D012221 Rhinitis, Allergic, Perennial DISEASE may_treat chlorpheniramine MEDRT D013224 Status Asthmaticus DISEASE ci_with chlorpheniramine maleate MEDRT D013224 Status Asthmaticus DISEASE ci_with chlorpheniramine MEDRT D001748 Urinary Bladder Neck Obstruction DISEASE ci_with chlorpheniramine MEDRT D001748 Urinary Bladder Neck Obstruction DISEASE ci_with chlorpheniramine maleate MEDRT D014581 Urticaria DISEASE may_treat chlorpheniramine maleate MEDRT D014581 Urticaria DISEASE may_treat chlorpheniramine MEDRT N0000000190 Histamine H1 Receptor Antagonists MOA has_moa chlorpheniramine maleate MEDRT N0000000190 Histamine H1 Receptor Antagonists MOA has_moa chlorpheniramine MEDRT N0000000184 Monoamine Oxidase Inhibitors MOA ci_moa dextromethorphan MEDRT N0000000184 Monoamine Oxidase Inhibitors MOA ci_moa dextromethorphan hydrobromide MEDRT N0000000108 Prostaglandin Receptor Antagonists MOA has_moa acetaminophen MEDRT N0000000109 Serotonin Uptake Inhibitors MOA has_moa dextromethorphan hydrobromide MEDRT N0000000109 Serotonin Uptake Inhibitors MOA has_moa dextromethorphan MEDRT N0000182147 Sigma-1 Receptor Agonists MOA has_moa dextromethorphan MEDRT N0000182147 Sigma-1 Receptor Agonists MOA has_moa dextromethorphan hydrobromide MEDRT N0000181819 Uncompetitive NMDA Receptor Antagonists MOA has_moa dextromethorphan MEDRT N0000181819 Uncompetitive NMDA Receptor Antagonists MOA has_moa dextromethorphan hydrobromide MEDRT N0000175724 Central Nervous System Activity Alteration PE has_pe acetaminophen MEDRT N0000008657 Decreased Histamine Activity PE has_pe chlorpheniramine maleate MEDRT N0000008657 Decreased Histamine Activity PE has_pe chlorpheniramine MEDRT N0000008701 Decreased Medullary Respiratory Drive PE has_pe dextromethorphan MEDRT N0000008701 Decreased Medullary Respiratory Drive PE has_pe dextromethorphan hydrobromide MEDRT N0000008836 Decreased Prostaglandin Production PE has_pe acetaminophen MEDRT N0000009072 Hypothalamic Endocrine Activity Alteration PE has_pe acetaminophen MEDRT N0000175725 Peripheral Nervous System Activity Alteration PE has_pe acetaminophen MEDRT N0000000026 Hepatic Metabolism PK has_pk acetaminophen MEDRT N0000000042 Renal Excretion PK has_pk acetaminophen
Properties# Category, Property, Value table Category Property Value ATTRIBUTES AVAILABLE_STRENGTH 21.7 MG/ML / 0.133 MG/ML / 1 MG/ML ATTRIBUTES GENERAL_CARDINALITY MULTI ATTRIBUTES HUMAN_DRUG US ATTRIBUTES PRESCRIBABLE Y ATTRIBUTES RXNAV_HUMAN_DRUG US ATTRIBUTES SCHEDULE 0 ATTRIBUTES TTY SCD CODES MMSL_CODE BD28704 CODES MMSL_CODE CD28704 CODES RxCUI 1046384 CODES SPL_SET_ID ec57c15e-cb6d-44a9-e053-2a95a90ae774 NAMES Prescribable Synonym acetaminophen 650 MG / chlorpheniramine maleate 4 MG / dextromethorphan HBr 30 MG in 30 mL Oral Solution NAMES RXNAV_STR acetaminophen 21.7 MG/ML / chlorpheniramine maleate 0.133 MG/ML / dextromethorphan hydrobromide 1 MG/ML Oral Solution NAMES RxNorm Name acetaminophen 21.7 MG/ML / chlorpheniramine maleate 0.133 MG/ML / dextromethorphan hydrobromide 1 MG/ML Oral Solution NAMES RxNorm Synonym acetaminophen 325 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG per 15 ML Oral Solution NAMES RxNorm Synonym acetaminophen 650 MG / chlorpheniramine maleate 4 MG / dextromethorphan hydrobromide 30 MG per 30 ML Oral Solution NAMES RxNorm Synonym APAP 21.7 MG/ML / Chlorpheniramine Maleate 0.133 MG/ML / Dextromethorphan Hydrobromide 1 MG/ML Oral Solution SOURCES Source Metathesaurus FDA Structured Product Labels SOURCES Source Micromedex RED BOOK SOURCES Source Multum MediSource Lexicon SOURCES Source National Drug Data File Plus Source Vocabulary