FDA.reportPublic FDA data

diphenhydramine hydrochloride 25 MG Oral Capsule [Benadryl]

RxCUI
1049910
RxNorm name
diphenhydramine hydrochloride 25 MG Oral Capsule [Benadryl]
Display name
BENADRYL (Oral Pill)
Full name
diphenhydramine hydrochloride 25 MG Oral Capsule [Benadryl]
Term type
SBD
Status
Active
Strength
25 mg
Dose form
Cap
Route
Oral Pill
Updated
2026-07-24 06:49:47

RxNorm Status History#

Status
Active
Source
RXNORM
Current
YES
Release start
012011
Active start
012011
Multiple ingredient
NO
Branded
YES

Ingredients And Strength#

Ingredient, Strength, Base table
IngredientStrengthBaseBasis of strength
diphenhydramine hydrochloride25 MG / 1 EACHdiphenhydraminediphenhydramine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose formRxCUI
Oral Capsule316965

Derived Ingredient Concepts#

Ingredient, RxCUI table
IngredientRxCUI
diphenhydramine3498

Source Vocabulary Codes#

Code type, Values, Count table
Code typeValuesCountCategory
PRESCRIBABLEY1ATTRIBUTES
RXNAV_STRBenadryl 25 MG Oral Capsule1NAMES
RxNorm Namediphenhydramine hydrochloride 25 MG Oral Capsule [Benadryl]1NAMES
RxNorm Synonym
2 linked values
2NAMES
TTYSBD1ATTRIBUTES
SPL_SET_IDbfeae100-e2d1-4607-be3b-2d9b15cd4f7f1CODES
RxCUI10499101CODES
MMSL_CODEBD34041CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDCProduct NDCNameLabelerApplication
50580-228-2450580-228Benadryl Allergy Liqui-Gels diphenhydramine hydrochlorideKenvue Brands LLCM012
50580-228-4850580-228Benadryl Allergy Liqui-Gels diphenhydramine hydrochlorideKenvue Brands LLCM012
50580-228-4950580-228Benadryl Allergy Liqui-Gels diphenhydramine hydrochlorideKenvue Brands LLCM012

Drugs@FDA Applications#

Application, NDC, Name table
ApplicationNDCNameMarketing categoryLabeler
M01250580-228Benadryl Allergy Liqui-Gels diphenhydramine hydrochlorideOTC MONOGRAPH DRUGKenvue Brands LLC

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 13 matching rows.

NDC11, Source, Active table
NDC11SourceActive
00501200124rxnav_ndcsyes
50580022824rxnav_ndcsyes
50580022848rxnav_ndcsyes
50580022849rxnav_ndcsyes
00071047124rxnav_historical
00071084013rxnav_historical
00071084018rxnav_historical
00501200024rxnav_historical
00501200048rxnav_historical
12280006824rxnav_historical
12280006830rxnav_historical
12547017021rxnav_historical
76413033224rxnav_historical

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Benadryl Allergy Liqui-GelsDIPHENHYDRAMINE HYDROCHLORIDEKenvue Brands LLCbfeae100-e2d1-4607-be3b-2d9b15cd4f7f2026-05-07WarningsExact identifier
ndc (package): 50580-228-24
ndc (package): 50580-228-48
ndc (package): 50580-228-49
ndc (product): 50580-228
ndc11 (package): 50580022848
ndc11 (package): 50580022824
ndc11 (package): 50580022849
rxcui: 1049910

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 2 matching rows.

Set ID, RxNorm mappings, Terms table
Set IDRxNorm mappingsTermsSPL versionLabelEffective
bfeae100-e2d1-4607-be3b-2d9b15cd4f7fBenadryl Allergy Liqui-Gel 25 MG Oral Capsule [PSN] · diphenhydramine hydrochloride 25 MG Oral Capsule [Benadryl] [SBD] · Benadryl 25 MG Oral Capsule [SY] · Benadryl Dye-Free Allergy 25 MG Oral Capsule [SY]410Benadryl ® Allergy Liqui-Gels ®20260507
0bbc8617-3833-4a97-9749-7c0e793fc9c5Benadryl Allergy Liqui-Gel 25 MG Oral Capsule [PSN] · diphenhydramine hydrochloride 25 MG Oral Capsule [Benadryl] [SBD] · Benadryl 25 MG Oral Capsule [SY] · Benadryl Dye-Free Allergy 25 MG Oral Capsule [SY]41Benadryl ® Allergy Liqui-Gels ®20170829

Recently Linked DailyMed Labels#

Set ID, Title, Manufacturer table
Set IDTitleManufacturerEffective
bfeae100-e2d1-4607-be3b-2d9b15cd4f7fBenadryl ® Allergy Liqui-Gels ®Kenvue Brands LLC20260507
0bbc8617-3833-4a97-9749-7c0e793fc9c5Benadryl ® Allergy Liqui-Gels ®Central Texas Community Health Centers20170829

Drug Classes#

Source, Class ID, Class table
SourceClass IDClassTypeRelationshipDrug concept
ATCR06AAAminoalkyl ethersATC1-4diphenhydramine
ATCD04AAAntihistamines for topical useATC1-4diphenhydramine
FDASPLN0000175587Histamine-1 Receptor AntagonistEPChas_epcdiphenhydramine
FDASPLN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine
MEDRTD004155DiphenhydramineCHEMhas_ingredientdiphenhydramine hydrochloride
MEDRTD004155DiphenhydramineCHEMhas_ingredientdiphenhydramine
MEDRTD001008Anxiety DisordersDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD001008Anxiety DisordersDISEASEmay_treatdiphenhydramine
MEDRTD004342Drug HypersensitivityDISEASEci_withdiphenhydramine hydrochloride
MEDRTD004342Drug HypersensitivityDISEASEci_withdiphenhydramine
MEDRTD007231Infant, NewbornDISEASEci_withdiphenhydramine hydrochloride
MEDRTD007231Infant, NewbornDISEASEci_withdiphenhydramine
MEDRTD007234Infant, PrematureDISEASEci_withdiphenhydramine hydrochloride
MEDRTD007234Infant, PrematureDISEASEci_withdiphenhydramine
MEDRTD007774LactationDISEASEci_withdiphenhydramine hydrochloride
MEDRTD007774LactationDISEASEci_withdiphenhydramine
MEDRTD009041Motion SicknessDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD009041Motion SicknessDISEASEmay_treatdiphenhydramine
MEDRTD009325NauseaDISEASEmay_treatdiphenhydramine
MEDRTD009325NauseaDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatdiphenhydramine
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD007319Sleep Initiation and Maintenance DisordersDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD007319Sleep Initiation and Maintenance DisordersDISEASEmay_treatdiphenhydramine
MEDRTD012912SneezingDISEASEmay_treatdiphenhydramine
MEDRTD012912SneezingDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD013224Status AsthmaticusDISEASEci_withdiphenhydramine
MEDRTD013224Status AsthmaticusDISEASEci_withdiphenhydramine hydrochloride
MEDRTD014581UrticariaDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD014581UrticariaDISEASEmay_treatdiphenhydramine
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine hydrochloride
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine

Properties#

Category, Property, Value table
CategoryPropertyValue
ATTRIBUTESAVAILABLE_STRENGTH25 MG
ATTRIBUTESGENERAL_CARDINALITYSINGLE
ATTRIBUTESHUMAN_DRUGUS
ATTRIBUTESRXNAV_HUMAN_DRUGUS
ATTRIBUTESSCHEDULE0
NAMESPrescribable SynonymBenadryl Allergy Liqui-Gel 25 MG Oral Capsule
NAMESTallman SynonymdiphenhydrAMINE hydrochloride 25 MG Oral Capsule [Benadryl]
SOURCESSourceGold Standard Alchemy
SOURCESSourceMetathesaurus FDA Structured Product Labels
SOURCESSourceMicromedex RED BOOK
SOURCESSourceMultum MediSource Lexicon