diphenhydramine hydrochloride 25 MG Oral Capsule [Benadryl]
- RxCUI
- 1049910
- RxNorm name
- diphenhydramine hydrochloride 25 MG Oral Capsule [Benadryl]
- Display name
- BENADRYL (Oral Pill)
- Full name
- diphenhydramine hydrochloride 25 MG Oral Capsule [Benadryl]
- Term type
- SBD
- Status
- Active
- Strength
- 25 mg
- Dose form
- Cap
- Route
- Oral Pill
- Updated
- 2026-07-24 06:49:47
RxNorm Status History#
- Status
- Active
- Source
- RXNORM
- Current
- YES
- Release start
- 012011
- Active start
- 012011
- Multiple ingredient
- NO
- Branded
- YES
Ingredients And Strength#
Ingredient, Strength, Base table| Ingredient | Strength | Base | Basis of strength |
|---|
| diphenhydramine hydrochloride | 25 MG / 1 EACH | diphenhydramine | diphenhydramine hydrochloride |
Derived Ingredient Concepts#
FDA NDC Products And Packages#
Package NDC, Product NDC, Name table| Package NDC | Product NDC | Name | Labeler | Application |
|---|
| 50580-228-24 | 50580-228 | Benadryl Allergy Liqui-Gels diphenhydramine hydrochloride | Kenvue Brands LLC | M012 |
| 50580-228-48 | 50580-228 | Benadryl Allergy Liqui-Gels diphenhydramine hydrochloride | Kenvue Brands LLC | M012 |
| 50580-228-49 | 50580-228 | Benadryl Allergy Liqui-Gels diphenhydramine hydrochloride | Kenvue Brands LLC | M012 |
Drugs@FDA Applications#
Application, NDC, Name table| Application | NDC | Name | Marketing category | Labeler |
|---|
| M012 | 50580-228 | Benadryl Allergy Liqui-Gels diphenhydramine hydrochloride | OTC MONOGRAPH DRUG | Kenvue Brands LLC |
RxNav Current And Historical NDCs#
NDC11, Source, Active table| NDC11 | Source | Active |
|---|
| 00501200124 | rxnav_ndcs | yes |
| 50580022824 | rxnav_ndcs | yes |
| 50580022848 | rxnav_ndcs | yes |
| 50580022849 | rxnav_ndcs | yes |
| 00071047124 | rxnav_historical | |
| 00071084013 | rxnav_historical | |
| 00071084018 | rxnav_historical | |
| 00501200024 | rxnav_historical | |
| 00501200048 | rxnav_historical | |
| 12280006824 | rxnav_historical | |
| 12280006830 | rxnav_historical | |
| 12547017021 | rxnav_historical | |
| 76413033224 | rxnav_historical | |
DailyMed RxNorm Mappings#
Drug Classes#
Source, Class ID, Class table| Source | Class ID | Class | Type | Relationship | Drug concept |
|---|
| ATC | R06AA | Aminoalkyl ethers | ATC1-4 | | diphenhydramine |
| ATC | D04AA | Antihistamines for topical use | ATC1-4 | | diphenhydramine |
| FDASPL | N0000175587 | Histamine-1 Receptor Antagonist | EPC | has_epc | diphenhydramine |
| FDASPL | N0000000190 | Histamine H1 Receptor Antagonists | MOA | has_moa | diphenhydramine |
| MEDRT | D004155 | Diphenhydramine | CHEM | has_ingredient | diphenhydramine hydrochloride |
| MEDRT | D004155 | Diphenhydramine | CHEM | has_ingredient | diphenhydramine |
| MEDRT | D001008 | Anxiety Disorders | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D001008 | Anxiety Disorders | DISEASE | may_treat | diphenhydramine |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | diphenhydramine |
| MEDRT | D007231 | Infant, Newborn | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D007231 | Infant, Newborn | DISEASE | ci_with | diphenhydramine |
| MEDRT | D007234 | Infant, Premature | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D007234 | Infant, Premature | DISEASE | ci_with | diphenhydramine |
| MEDRT | D007774 | Lactation | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D007774 | Lactation | DISEASE | ci_with | diphenhydramine |
| MEDRT | D009041 | Motion Sickness | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D009041 | Motion Sickness | DISEASE | may_treat | diphenhydramine |
| MEDRT | D009325 | Nausea | DISEASE | may_treat | diphenhydramine |
| MEDRT | D009325 | Nausea | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D012221 | Rhinitis, Allergic, Perennial | DISEASE | may_treat | diphenhydramine |
| MEDRT | D012221 | Rhinitis, Allergic, Perennial | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D007319 | Sleep Initiation and Maintenance Disorders | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D007319 | Sleep Initiation and Maintenance Disorders | DISEASE | may_treat | diphenhydramine |
| MEDRT | D012912 | Sneezing | DISEASE | may_treat | diphenhydramine |
| MEDRT | D012912 | Sneezing | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D013224 | Status Asthmaticus | DISEASE | ci_with | diphenhydramine |
| MEDRT | D013224 | Status Asthmaticus | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D014581 | Urticaria | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D014581 | Urticaria | DISEASE | may_treat | diphenhydramine |
| MEDRT | N0000000190 | Histamine H1 Receptor Antagonists | MOA | has_moa | diphenhydramine hydrochloride |
| MEDRT | N0000000190 | Histamine H1 Receptor Antagonists | MOA | has_moa | diphenhydramine |
Properties#
Category, Property, Value table| Category | Property | Value |
|---|
| ATTRIBUTES | AVAILABLE_STRENGTH | 25 MG |
| ATTRIBUTES | GENERAL_CARDINALITY | SINGLE |
| ATTRIBUTES | HUMAN_DRUG | US |
| ATTRIBUTES | PRESCRIBABLE | Y |
| ATTRIBUTES | RXNAV_HUMAN_DRUG | US |
| ATTRIBUTES | SCHEDULE | 0 |
| ATTRIBUTES | TTY | SBD |
| CODES | MMSL_CODE | BD3404 |
| CODES | RxCUI | 1049910 |
| CODES | SPL_SET_ID | bfeae100-e2d1-4607-be3b-2d9b15cd4f7f |
| NAMES | Prescribable Synonym | Benadryl Allergy Liqui-Gel 25 MG Oral Capsule |
| NAMES | RXNAV_STR | Benadryl 25 MG Oral Capsule |
| NAMES | RxNorm Name | diphenhydramine hydrochloride 25 MG Oral Capsule [Benadryl] |
| NAMES | RxNorm Synonym | Benadryl 25 MG Oral Capsule |
| NAMES | RxNorm Synonym | Benadryl Dye-Free Allergy 25 MG Oral Capsule |
| NAMES | Tallman Synonym | diphenhydrAMINE hydrochloride 25 MG Oral Capsule [Benadryl] |
| SOURCES | Source | Gold Standard Alchemy |
| SOURCES | Source | Metathesaurus FDA Structured Product Labels |
| SOURCES | Source | Micromedex RED BOOK |
| SOURCES | Source | Multum MediSource Lexicon |