acetaminophen 32 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution

RxCUI: 1050385
RxNorm name: acetaminophen 32 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution
Display name: Acetaminophen/diphenhydrAMINE/Phenylephrine (Oral Liquid)
Full name: acetaminophen 32 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution
Term type: SCD
Status: Active
Strength: 160-6.25-2.5 mg/5ml
Dose form: Sol
Route: Oral Liquid
Updated: 2026-06-13 07:09:22

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 012011
Active start: 012011
Multiple ingredient: YES
Branded: NO

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
acetaminophen	32 MG / 1 ML	acetaminophen	acetaminophen
diphenhydramine hydrochloride	1.25 MG / 1 ML	diphenhydramine	diphenhydramine hydrochloride
phenylephrine hydrochloride	0.5 MG / 1 ML	phenylephrine	phenylephrine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Oral Solution	316968

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
acetaminophen	161
diphenhydramine	3498
phenylephrine	8163

Source Vocabulary Codes#

Code type, Value, Category table
Code type	Value	Category
PRESCRIBABLE	Y	ATTRIBUTES
RXNAV_STR	acetaminophen 32 MG/ML / diphenhydrAMINE hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution	NAMES
RxNorm Name	acetaminophen 32 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution	NAMES
RxNorm Synonym	acetaminophen 640 MG / diphenhydramine hydrochloride 25 MG / phenylephrine hydrochloride 10 MG per 20 ML Oral Solution	NAMES
RxNorm Synonym	APAP 160 MG / diphenhydramine HCl 6.25 MG / phenylephrine HCl 2.5 MG per 5 ML Oral Solution	NAMES
RxNorm Synonym	APAP 32 MG/ML / Diphenhydramine Hydrochloride 1.25 MG/ML / Phenylephrine Hydrochloride 0.5 MG/ML Oral Solution	NAMES
TTY	SCD	ATTRIBUTES
RxCUI	1050385	CODES
MMSL_CODE	BD27088	CODES
MMSL_CODE	BD30184	CODES
MMSL_CODE	CD27088	CODES
MMSL_CODE	CD30184	CODES

RxNav Current And Historical NDCs#

NDC11, Source, Active table
NDC11	Source	Active
00031224904	rxnav_ndcs	yes
59779009504	rxnav_ndcs	yes
80070033004	rxnav_ndcs	yes
00031862812	rxnav_historical_indirect
00031862818	rxnav_historical_indirect
00031873512	rxnav_historical
00031873518	rxnav_historical
00318064212	rxnav_historical_indirect
00318064218	rxnav_historical_indirect
30142094930	rxnav_historical

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	C01CA	Adrenergic and dopaminergic agents	ATC1-4		phenylephrine
ATC	R06AA	Aminoalkyl ethers	ATC1-4		diphenhydramine
ATC	N02BE	Anilides	ATC1-4		acetaminophen
ATC	D04AA	Antihistamines for topical use	ATC1-4		diphenhydramine
ATC	C05AX	Other agents for treatment of hemorrhoids and anal fissures for topical use	ATC1-4		phenylephrine
ATC	R01BA	Sympathomimetics	ATC1-4		phenylephrine
ATC	S01FB	Sympathomimetics excl. antiglaucoma preparations	ATC1-4		phenylephrine
ATC	S01GA	Sympathomimetics used as decongestants	ATC1-4		phenylephrine
ATC	R01AB	Sympathomimetics, combinations excl. corticosteroids	ATC1-4		phenylephrine
ATC	R01AA	Sympathomimetics, plain	ATC1-4		phenylephrine
FDASPL	N0000186105	alpha-1 Adrenergic Agonist	EPC	has_epc	phenylephrine
FDASPL	N0000175587	Histamine-1 Receptor Antagonist	EPC	has_epc	diphenhydramine
FDASPL	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	diphenhydramine
MEDRT	D000082	Acetaminophen	CHEM	has_ingredient	acetaminophen
MEDRT	D004155	Diphenhydramine	CHEM	has_ingredient	diphenhydramine hydrochloride
MEDRT	D004155	Diphenhydramine	CHEM	has_ingredient	diphenhydramine
MEDRT	D010656	Phenylephrine	CHEM	has_ingredient	phenylephrine
MEDRT	D010656	Phenylephrine	CHEM	has_ingredient	phenylephrine hydrochloride
MEDRT	D013447	Sulfites	CHEM	ci_chemclass	phenylephrine
MEDRT	D013447	Sulfites	CHEM	ci_chemclass	phenylephrine hydrochloride
MEDRT	D001008	Anxiety Disorders	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D001008	Anxiety Disorders	DISEASE	may_treat	diphenhydramine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	diphenhydramine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	acetaminophen
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	phenylephrine
MEDRT	D005334	Fever	DISEASE	may_treat	acetaminophen
MEDRT	D005334	Fever	DISEASE	may_prevent	acetaminophen
MEDRT	D005401	Fissure in Ano	DISEASE	may_treat	phenylephrine
MEDRT	D005401	Fissure in Ano	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D005902	Glaucoma, Open-Angle	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D005902	Glaucoma, Open-Angle	DISEASE	may_treat	phenylephrine
MEDRT	D005955	Glucosephosphate Dehydrogenase Deficiency	DISEASE	ci_with	acetaminophen
MEDRT	D006484	Hemorrhoids	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D006484	Hemorrhoids	DISEASE	may_treat	phenylephrine
MEDRT	D006973	Hypertension	DISEASE	ci_with	phenylephrine
MEDRT	D006973	Hypertension	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D007022	Hypotension	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D007022	Hypotension	DISEASE	may_treat	phenylephrine
MEDRT	D007231	Infant, Newborn	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D007231	Infant, Newborn	DISEASE	ci_with	diphenhydramine
MEDRT	D007234	Infant, Premature	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D007234	Infant, Premature	DISEASE	ci_with	diphenhydramine
MEDRT	D007774	Lactation	DISEASE	ci_with	diphenhydramine
MEDRT	D007774	Lactation	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D008107	Liver Diseases	DISEASE	ci_with	acetaminophen
MEDRT	D009041	Motion Sickness	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D009041	Motion Sickness	DISEASE	may_treat	diphenhydramine
MEDRT	D015878	Mydriasis	DISEASE	induces	phenylephrine
MEDRT	D015878	Mydriasis	DISEASE	induces	phenylephrine hydrochloride
MEDRT	D009325	Nausea	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D009325	Nausea	DISEASE	may_treat	diphenhydramine
MEDRT	D010146	Pain	DISEASE	may_treat	acetaminophen
MEDRT	D010146	Pain	DISEASE	may_prevent	acetaminophen
MEDRT	D011538	Pruritus Ani	DISEASE	may_treat	phenylephrine
MEDRT	D011538	Pruritus Ani	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	diphenhydramine
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D012223	Rhinitis, Vasomotor	DISEASE	may_treat	phenylephrine
MEDRT	D012223	Rhinitis, Vasomotor	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D012772	Shock, Septic	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D012772	Shock, Septic	DISEASE	may_treat	phenylephrine
MEDRT	D007319	Sleep Initiation and Maintenance Disorders	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D007319	Sleep Initiation and Maintenance Disorders	DISEASE	may_treat	diphenhydramine
MEDRT	D012912	Sneezing	DISEASE	may_treat	diphenhydramine
MEDRT	D012912	Sneezing	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D013224	Status Asthmaticus	DISEASE	ci_with	diphenhydramine
MEDRT	D013224	Status Asthmaticus	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D013617	Tachycardia, Supraventricular	DISEASE	may_treat	phenylephrine
MEDRT	D013617	Tachycardia, Supraventricular	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	ci_with	phenylephrine
MEDRT	D014581	Urticaria	DISEASE	may_treat	diphenhydramine
MEDRT	D014581	Urticaria	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	phenylephrine
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	phenylephrine hydrochloride
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	diphenhydramine hydrochloride
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	diphenhydramine
MEDRT	N0000000108	Prostaglandin Receptor Antagonists	MOA	has_moa	acetaminophen
MEDRT	N0000175724	Central Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000008371	Conjunctival Arterial Vasoconstriction	PE	has_pe	phenylephrine
MEDRT	N0000008371	Conjunctival Arterial Vasoconstriction	PE	has_pe	phenylephrine hydrochloride
MEDRT	N0000008896	Decreased Nasal and Sinus Secretions	PE	has_pe	phenylephrine hydrochloride
MEDRT	N0000008896	Decreased Nasal and Sinus Secretions	PE	has_pe	phenylephrine
MEDRT	N0000008836	Decreased Prostaglandin Production	PE	has_pe	acetaminophen
MEDRT	N0000009072	Hypothalamic Endocrine Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000175725	Peripheral Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000000026	Hepatic Metabolism	PK	has_pk	acetaminophen
MEDRT	N0000000042	Renal Excretion	PK	has_pk	acetaminophen

Group, Type, Concept table
Group	Type	Concept	Source
DF	DF	Oral Solution	rxnav_allrelated
DFG	DFG	Oral Liquid Product	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
IN	IN	acetaminophen	rxnav_allrelated
IN	IN	diphenhydramine	rxnav_allrelated
IN	IN	phenylephrine	rxnav_allrelated
MIN	MIN	acetaminophen / diphenhydramine / phenylephrine	rxnav_allrelated
PIN	PIN	diphenhydramine hydrochloride	rxnav_allrelated
PIN	PIN	phenylephrine hydrochloride	rxnav_allrelated
SCD	SCD	acetaminophen 32 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution	rxnav_allrelated
SCDC	SCDC	acetaminophen 32 MG/ML	rxnav_allrelated
SCDC	SCDC	diphenhydramine hydrochloride 1.25 MG/ML	rxnav_allrelated
SCDC	SCDC	phenylephrine hydrochloride 0.5 MG/ML	rxnav_allrelated
SCDF	SCDF	acetaminophen / diphenhydramine / phenylephrine Oral Solution	rxnav_allrelated
SCDFP	SCDFP	acetaminophen / diphenhydramine hydrochloride / phenylephrine hydrochloride Oral Solution	rxnav_allrelated
SCDG	SCDG	acetaminophen / diphenhydramine / phenylephrine Oral Liquid Product	rxnav_allrelated
SCDG	SCDG	acetaminophen / diphenhydramine / phenylephrine Oral Product	rxnav_allrelated
SCDGP	SCDGP	acetaminophen / diphenhydramine hydrochloride / phenylephrine hydrochloride Oral Liquid Product	rxnav_allrelated
SCDGP	SCDGP	acetaminophen / diphenhydramine hydrochloride / phenylephrine hydrochloride Oral Product	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	32 MG/ML / 1.25 MG/ML / 0.5 MG/ML
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	PRESCRIBABLE	Y
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
ATTRIBUTES	SCHEDULE	0
ATTRIBUTES	TTY	SCD
CODES	MMSL_CODE	BD27088
CODES	MMSL_CODE	BD30184
CODES	MMSL_CODE	CD27088
CODES	MMSL_CODE	CD30184
CODES	RxCUI	1050385
NAMES	Prescribable Synonym	acetaminophen 160 MG / diphenhydrAMINE HCl 6.25 MG / phenylephrine HCl 2.5 MG in 5 mL Oral Solution
NAMES	RXNAV_STR	acetaminophen 32 MG/ML / diphenhydrAMINE hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution
NAMES	RxNorm Name	acetaminophen 32 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution
NAMES	RxNorm Synonym	acetaminophen 640 MG / diphenhydramine hydrochloride 25 MG / phenylephrine hydrochloride 10 MG per 20 ML Oral Solution
NAMES	RxNorm Synonym	APAP 160 MG / diphenhydramine HCl 6.25 MG / phenylephrine HCl 2.5 MG per 5 ML Oral Solution
NAMES	RxNorm Synonym	APAP 32 MG/ML / Diphenhydramine Hydrochloride 1.25 MG/ML / Phenylephrine Hydrochloride 0.5 MG/ML Oral Solution
NAMES	Tallman Synonym	acetaminophen 32 MG/ML / diphenhydrAMINE hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution
NAMES	Tallman Synonym	acetaminophen 640 MG / diphenhydrAMINE hydrochloride 25 MG / phenylephrine hydrochloride 10 MG per 20 ML Oral Solution
NAMES	Tallman Synonym	APAP 160 MG / diphenhydrAMINE HCl 6.25 MG / phenylephrine HCl 2.5 MG per 5 ML Oral Solution
NAMES	Tallman Synonym	APAP 32 MG/ML / diphenhydrAMINE Hydrochloride 1.25 MG/ML / Phenylephrine Hydrochloride 0.5 MG/ML Oral Solution
SOURCES	Source	Gold Standard Alchemy
SOURCES	Source	Multum MediSource Lexicon
SOURCES	Source	National Drug Data File Plus Source Vocabulary

acetaminophen 32 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution

RxNorm Status History#

Ingredients And Strength#

Dose Form Concepts#

Derived Ingredient Concepts#

Source Vocabulary Codes#

RxNav Current And Historical NDCs#

Drug Classes#

Related Concepts#

Properties#