acetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral Capsule

RxCUI
1052647
RxNorm name
acetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral Capsule
Display name
Acetaminophen/Doxylamine/Phenylephrine (Oral Pill)
Full name
acetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral Capsule
Term type
SCD
Status
Active
Strength
325-6.25-5 mg
Dose form
Cap
Route
Oral Pill
Updated
2026-06-13 07:09:28

RxNorm Status History#

Status
Active
Source
RXNORM
Current
YES
Release start
022011
Active start
022011
Multiple ingredient
YES
Branded
NO

Ingredients And Strength#

Ingredient, Strength, Base table
IngredientStrengthBaseBasis of strength
acetaminophen325 MG / 1 EACHacetaminophenacetaminophen
doxylamine succinate6.25 MG / 1 EACHdoxylaminedoxylamine succinate
phenylephrine hydrochloride5 MG / 1 EACHphenylephrinephenylephrine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose formRxCUI
Oral Capsule316965

Derived Ingredient Concepts#

Ingredient, RxCUI table
IngredientRxCUI
acetaminophen161
doxylamine3642
phenylephrine8163

Source Vocabulary Codes#

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDCProduct NDCNameLabelerApplication
53345-013-0153345-013NightTime Sinus Relief Acetaminophen, Doxylamine succinate, Phenylephrine hydrochlorideHumanwell PuraCap Pharmaceutical (Wuhan), Ltd.M012
53345-031-0153345-031NightTime Sinus Acetaminophen, Doxylamine succinate, Phenylephrine hydrochlorideHumanwell PuraCap Pharmaceutical (Wuhan) Co., Ltd.M012

Drugs@FDA Applications#

Application, NDC, Name table
ApplicationNDCNameMarketing categoryLabeler
M01253345-013NightTime Sinus Relief Acetaminophen, Doxylamine succinate, Phenylephrine hydrochlorideOTC MONOGRAPH DRUGHumanwell PuraCap Pharmaceutical (Wuhan), Ltd.

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 39 matching rows.

NDC11, Source, Active table
NDC11SourceActive
23900002328rxnav_ndcsyes
51013011314rxnav_ndcsyes
53345001301rxnav_ndcsyes
53345003101rxnav_ndcsyes
68016020116rxnav_ndcsyes
68016063116rxnav_ndcsyes
00280119820rxnav_historical
23900001448rxnav_historical
23900001983rxnav_historical
36800010116rxnav_historical
36800010124rxnav_historical
36800040862rxnav_historical
37000040824rxnav_historical
37000050824rxnav_historical
37000080620rxnav_historical_indirect
37000080624rxnav_historical
41250010124rxnav_historical
41250024762rxnav_historical
41520010116rxnav_historical
42507030562rxnav_historical
46122000660rxnav_historical
49035024760rxnav_historical
50804010124rxnav_historical
51013015604rxnav_historical
51013016004rxnav_historical
51013018614rxnav_historical
55312010112rxnav_historical
55312010116rxnav_historical
55315010216rxnav_historical
59726010108rxnav_historical
59779010116rxnav_historical
59995000700rxnav_historical
63868038812rxnav_historical
63868038820rxnav_historical
68016010112rxnav_historical
68016073316rxnav_historical
68210148005rxnav_historical
68210148006rxnav_historical
76270011408rxnav_historical

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
NightTime Sinus ReliefACETAMINOPHEN, DOXYLAMINE SUCCINATE, PHENYLEPHRINE HYDROCHLORIDEHumanwell PuraCap Pharmaceutical (Wuhan), Ltd.413d82d3-a896-4f15-9fca-c1b7b9a1ee632024-11-25WarningsExact identifier
ndc (package): 53345-013-01
ndc (product): 53345-013
ndc11 (package): 53345001301
rxcui: 1052647
NightTime SinusACETAMINOPHEN, DOXYLAMINE SUCCINATE, PHENYLEPHRINE HYDROCHLORIDEHumanwell PuraCap Pharmaceutical (Wuhan) Co., Ltd.0f3b1404-9252-470a-aa8c-b360c85731f32024-11-25WarningsExact identifier
ndc (package): 53345-031-01
ndc (product): 53345-031
ndc11 (package): 53345003101
rxcui: 1052647

DailyMed RxNorm Mappings#

Set ID, RxNorm string, TTY table
Set IDRxNorm stringTTYSPL versionLabelEffective
0f3b1404-9252-470a-aa8c-b360c85731f3acetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine HCl 5 MG Oral CapsulePSN3NightTime Sinus Capsule, liquid filled20241125
0f3b1404-9252-470a-aa8c-b360c85731f3acetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral CapsuleSCD3NightTime Sinus Capsule, liquid filled20241125
0f3b1404-9252-470a-aa8c-b360c85731f3APAP 325 MG / doxylamine succinate 6.25 MG / Phenylephrine Hydrochloride 5 MG Oral CapsuleSY3NightTime Sinus Capsule, liquid filled20241125
413d82d3-a896-4f15-9fca-c1b7b9a1ee63APAP 325 MG / doxylamine succinate 6.25 MG / Phenylephrine Hydrochloride 5 MG Oral CapsuleSY3NightTime Sinus Relief capsule, liquid filled20241125
413d82d3-a896-4f15-9fca-c1b7b9a1ee63acetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine HCl 5 MG Oral CapsulePSN3NightTime Sinus Relief capsule, liquid filled20241125
413d82d3-a896-4f15-9fca-c1b7b9a1ee63acetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral CapsuleSCD3NightTime Sinus Relief capsule, liquid filled20241125
649f429a-ba62-4ef0-9c7f-940bbf18dbf0acetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral CapsuleSCD2Night Time Sinus Relief20200103
649f429a-ba62-4ef0-9c7f-940bbf18dbf0APAP 325 MG / doxylamine succinate 6.25 MG / Phenylephrine Hydrochloride 5 MG Oral CapsuleSY2Night Time Sinus Relief20200103
649f429a-ba62-4ef0-9c7f-940bbf18dbf0acetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine HCl 5 MG Oral CapsulePSN2Night Time Sinus Relief20200103
d538445e-a47d-4983-844f-38aa303d11fdAPAP 325 MG / doxylamine succinate 6.25 MG / Phenylephrine Hydrochloride 5 MG Oral CapsuleSY2Daytime Sinus Relief and Nighttime Sinus Relief20191230
d538445e-a47d-4983-844f-38aa303d11fdacetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine HCl 5 MG Oral CapsulePSN2Daytime Sinus Relief and Nighttime Sinus Relief20191230
d538445e-a47d-4983-844f-38aa303d11fdacetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral CapsuleSCD2Daytime Sinus Relief and Nighttime Sinus Relief20191230
4f1ceec0-1273-4cfd-8263-f4247b5e7ee6acetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine HCl 5 MG Oral CapsulePSN2Nighttime Sinus & Congestion Relief20191220
4f1ceec0-1273-4cfd-8263-f4247b5e7ee6APAP 325 MG / doxylamine succinate 6.25 MG / Phenylephrine Hydrochloride 5 MG Oral CapsuleSY2Nighttime Sinus & Congestion Relief20191220
4f1ceec0-1273-4cfd-8263-f4247b5e7ee6acetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral CapsuleSCD2Nighttime Sinus & Congestion Relief20191220
cd1ec9c1-54da-4b73-8d2c-6b727234142cAPAP 325 MG / doxylamine succinate 6.25 MG / Phenylephrine Hydrochloride 5 MG Oral CapsuleSY2NiteTime Sinus Relief20191220
cd1ec9c1-54da-4b73-8d2c-6b727234142cacetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine HCl 5 MG Oral CapsulePSN2NiteTime Sinus Relief20191220
cd1ec9c1-54da-4b73-8d2c-6b727234142cacetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral CapsuleSCD2NiteTime Sinus Relief20191220
e3be9ee0-b9bb-4a09-a40a-dbe2f08325adAPAP 325 MG / doxylamine succinate 6.25 MG / Phenylephrine Hydrochloride 5 MG Oral CapsuleSY2N-Time Sinus Soft Gelatin Capsules20100726
e3be9ee0-b9bb-4a09-a40a-dbe2f08325adacetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine HCl 5 MG Oral CapsulePSN2N-Time Sinus Soft Gelatin Capsules20100726
e3be9ee0-b9bb-4a09-a40a-dbe2f08325adacetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral CapsuleSCD2N-Time Sinus Soft Gelatin Capsules20100726
842706f9-eedf-1783-49ed-e6b7ae7d650eacetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine HCl 5 MG Oral CapsulePSN1Drug Facts20151012
842706f9-eedf-1783-49ed-e6b7ae7d650eacetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral CapsuleSCD1Drug Facts20151012
842706f9-eedf-1783-49ed-e6b7ae7d650eAPAP 325 MG / doxylamine succinate 6.25 MG / Phenylephrine Hydrochloride 5 MG Oral CapsuleSY1Drug Facts20151012

DailyMed Labels#

Set ID, Title, Manufacturer table
Set IDTitleManufacturerEffective
0f3b1404-9252-470a-aa8c-b360c85731f3NightTime Sinus Capsule, liquid filledHumanwell PuraCap Pharmaceutical (Wuhan) Co., Ltd.20241125
413d82d3-a896-4f15-9fca-c1b7b9a1ee63NightTime Sinus Relief capsule, liquid filledHumanwell PuraCap Pharmaceutical (Wuhan), Ltd.20241125
5fda0fc7-956f-4861-8491-259c1abcadd2Drug FactsMEIJER, INC.20230112
208409b1-03cb-4da5-9494-48d0c15bb8e7Drug FactsFreds Inc20211019
3a36815b-7974-6111-e054-00144ff88e88Vicks ® Sinex™ Nighttime Congestion, Pressure & PainThe Procter & Gamble Manufacturing Company20210709
649f429a-ba62-4ef0-9c7f-940bbf18dbf0Night Time Sinus ReliefPuraCap Pharmaceutical LLC | Humanwell PuraCap Pharmaceutical (Wuhan) Co., Ltd20200103
5c421f71-38f0-4215-8d73-f759888b9b6bDRUG FACTSGood Sense (Geiss, Destin & Dunn, Inc.)20191220
4f1ceec0-1273-4cfd-8263-f4247b5e7ee6Nighttime Sinus & Congestion ReliefPuraCap Pharmaceutical LLC | Humanwell PuraCap Pharmaceutical (Wuhan) Co., Ltd20191220
cd1ec9c1-54da-4b73-8d2c-6b727234142cNiteTime Sinus ReliefPuraCap Pharmaceutical LLC | Humanwell PuraCap Pharmaceutical (Wuhan) Co., Ltd20191220
dc65aeb9-b109-4432-8bde-11762e795fdaDrug FactsTOP CARE (Topco Associates LLC) | P & L Development, LLC20190807
7bf0a954-62ae-4d85-af04-10e6c9b521f2DRUG FACTSCare One (American Sales Company)20190715
39601d9e-692d-46fc-9edb-14c908c9de7dDRUG FACTSWestern Family Foods, Inc.20181228
8154cf5e-4c43-4814-8fb6-29806d5b1006DRUG FACTSP & L Development, LLC20181226
ff840853-a139-44fb-941a-e9c588f51b15DRUG FACTSChain Drug Consortium, LLC20151119
842706f9-eedf-1783-49ed-e6b7ae7d650eDrug FactsChain Drug Consortium, LLC | Accucaps Industries Limited | Accucaps Industries Limited Strathroy | Legacy Pharmaceutical Packaging20151012
03d4a566-dc15-4e5f-9532-c3b21db1368eNational Council for Prescription Drug Programs20130213
da66683c-5a88-4de5-bd03-78c052cce85aNational Council for Prescription Drug Programs20120724
e3be9ee0-b9bb-4a09-a40a-dbe2f08325adN-Time Sinus Soft Gelatin CapsulesSPIRIT PHARMACEUTICALS,LLC20100726

Drug Classes#

Source, Class ID, Class table
SourceClass IDClassTypeRelationshipDrug concept
ATCC01CAAdrenergic and dopaminergic agentsATC1-4phenylephrine
ATCR06AAAminoalkyl ethersATC1-4doxylamine
ATCN02BEAnilidesATC1-4acetaminophen
ATCC05AXOther agents for treatment of hemorrhoids and anal fissures for topical useATC1-4phenylephrine
ATCR01BASympathomimeticsATC1-4phenylephrine
ATCS01FBSympathomimetics excl. antiglaucoma preparationsATC1-4phenylephrine
ATCS01GASympathomimetics used as decongestantsATC1-4phenylephrine
ATCR01ABSympathomimetics, combinations excl. corticosteroidsATC1-4phenylephrine
ATCR01AASympathomimetics, plainATC1-4phenylephrine
FDASPLN0000186105alpha-1 Adrenergic AgonistEPChas_epcphenylephrine
FDASPLN0000175750AntihistamineEPChas_epcdoxylamine
FDASPLN0000000207Histamine Receptor AntagonistsMOAhas_moadoxylamine
MEDRTD000082AcetaminophenCHEMhas_ingredientacetaminophen
MEDRTD004319DoxylamineCHEMhas_ingredientdoxylamine succinate
MEDRTD004319DoxylamineCHEMhas_ingredientdoxylamine
MEDRTD010656PhenylephrineCHEMhas_ingredientphenylephrine hydrochloride
MEDRTD010656PhenylephrineCHEMhas_ingredientphenylephrine
MEDRTD013447SulfitesCHEMci_chemclassphenylephrine
MEDRTD013447SulfitesCHEMci_chemclassphenylephrine hydrochloride
MEDRTD004342Drug HypersensitivityDISEASEci_withphenylephrine hydrochloride
MEDRTD004342Drug HypersensitivityDISEASEci_withacetaminophen
MEDRTD004342Drug HypersensitivityDISEASEci_withdoxylamine succinate
MEDRTD004342Drug HypersensitivityDISEASEci_withphenylephrine
MEDRTD004342Drug HypersensitivityDISEASEci_withdoxylamine
MEDRTD005334FeverDISEASEmay_preventacetaminophen
MEDRTD005334FeverDISEASEmay_treatacetaminophen
MEDRTD005401Fissure in AnoDISEASEmay_treatphenylephrine hydrochloride
MEDRTD005401Fissure in AnoDISEASEmay_treatphenylephrine
MEDRTD005902Glaucoma, Open-AngleDISEASEmay_treatphenylephrine hydrochloride
MEDRTD005902Glaucoma, Open-AngleDISEASEmay_treatphenylephrine
MEDRTD005955Glucosephosphate Dehydrogenase DeficiencyDISEASEci_withacetaminophen
MEDRTD006261HeadacheDISEASEmay_treatdoxylamine
MEDRTD006261HeadacheDISEASEmay_treatdoxylamine succinate
MEDRTD006484HemorrhoidsDISEASEmay_treatphenylephrine hydrochloride
MEDRTD006484HemorrhoidsDISEASEmay_treatphenylephrine
MEDRTD006973HypertensionDISEASEci_withphenylephrine hydrochloride
MEDRTD006973HypertensionDISEASEci_withphenylephrine
MEDRTD007022HypotensionDISEASEmay_treatphenylephrine
MEDRTD007022HypotensionDISEASEmay_treatphenylephrine hydrochloride
MEDRTD008107Liver DiseasesDISEASEci_withacetaminophen
MEDRTD015878MydriasisDISEASEinducesphenylephrine hydrochloride
MEDRTD015878MydriasisDISEASEinducesphenylephrine
MEDRTD010146PainDISEASEmay_preventacetaminophen
MEDRTD010146PainDISEASEmay_treatacetaminophen
MEDRTD011538Pruritus AniDISEASEmay_treatphenylephrine
MEDRTD011538Pruritus AniDISEASEmay_treatphenylephrine hydrochloride
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatdoxylamine succinate
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatdoxylamine
MEDRTD012223Rhinitis, VasomotorDISEASEmay_treatphenylephrine
MEDRTD012223Rhinitis, VasomotorDISEASEmay_treatphenylephrine hydrochloride
MEDRTD012772Shock, SepticDISEASEmay_treatphenylephrine
MEDRTD012772Shock, SepticDISEASEmay_treatphenylephrine hydrochloride
MEDRTD007319Sleep Initiation and Maintenance DisordersDISEASEmay_treatdoxylamine succinate
MEDRTD007319Sleep Initiation and Maintenance DisordersDISEASEmay_treatdoxylamine
MEDRTD013617Tachycardia, SupraventricularDISEASEmay_treatphenylephrine
MEDRTD013617Tachycardia, SupraventricularDISEASEmay_treatphenylephrine hydrochloride
MEDRTD017180Tachycardia, VentricularDISEASEci_withphenylephrine
MEDRTD017180Tachycardia, VentricularDISEASEci_withphenylephrine hydrochloride
MEDRTN0000000209Adrenergic alpha-AgonistsMOAhas_moaphenylephrine
MEDRTN0000000209Adrenergic alpha-AgonistsMOAhas_moaphenylephrine hydrochloride
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadoxylamine succinate
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadoxylamine
MEDRTN0000000108Prostaglandin Receptor AntagonistsMOAhas_moaacetaminophen
MEDRTN0000175724Central Nervous System Activity AlterationPEhas_peacetaminophen
MEDRTN0000008371Conjunctival Arterial VasoconstrictionPEhas_pephenylephrine hydrochloride
MEDRTN0000008371Conjunctival Arterial VasoconstrictionPEhas_pephenylephrine
MEDRTN0000008657Decreased Histamine ActivityPEhas_pedoxylamine
MEDRTN0000008657Decreased Histamine ActivityPEhas_pedoxylamine succinate
MEDRTN0000008896Decreased Nasal and Sinus SecretionsPEhas_pephenylephrine hydrochloride
MEDRTN0000008896Decreased Nasal and Sinus SecretionsPEhas_pephenylephrine
MEDRTN0000008836Decreased Prostaglandin ProductionPEhas_peacetaminophen
MEDRTN0000009072Hypothalamic Endocrine Activity AlterationPEhas_peacetaminophen
MEDRTN0000175725Peripheral Nervous System Activity AlterationPEhas_peacetaminophen
MEDRTN0000000026Hepatic MetabolismPKhas_pkacetaminophen
MEDRTN0000000042Renal ExcretionPKhas_pkacetaminophen

Properties#

Category, Property, Value table
CategoryPropertyValue
ATTRIBUTESAVAILABLE_STRENGTH325 MG / 6.25 MG (expressed as doxylamine succinate) / 5 MG
ATTRIBUTESGENERAL_CARDINALITYMULTI
ATTRIBUTESHUMAN_DRUGUS
ATTRIBUTESPRESCRIBABLEY
ATTRIBUTESRXNAV_HUMAN_DRUGUS
ATTRIBUTESTTYSCD
CODESMMSL_CODEBD28700
CODESMMSL_CODECD28700
CODESRxCUI1052647
CODESSPL_SET_ID0f3b1404-9252-470a-aa8c-b360c85731f3
CODESSPL_SET_ID413d82d3-a896-4f15-9fca-c1b7b9a1ee63
CODESSPL_SET_IDd538445e-a47d-4983-844f-38aa303d11fd
NAMESPrescribable Synonymacetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine HCl 5 MG Oral Capsule
NAMESRXNAV_STRacetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral Capsule
NAMESRxNorm Nameacetaminophen 325 MG / doxylamine succinate 6.25 MG / phenylephrine hydrochloride 5 MG Oral Capsule
NAMESRxNorm SynonymAPAP 325 MG / doxylamine succinate 6.25 MG / Phenylephrine Hydrochloride 5 MG Oral Capsule
SOURCESSourceGold Standard Alchemy
SOURCESSourceMetathesaurus FDA Structured Product Labels