chlorpheniramine maleate 0.8 MG/ML / dextromethorphan hydrobromide 3 MG/ML / phenylephrine hydrochloride 2 MG/ML Oral Solution

RxCUI: 1086443
RxNorm name: chlorpheniramine maleate 0.8 MG/ML / dextromethorphan hydrobromide 3 MG/ML / phenylephrine hydrochloride 2 MG/ML Oral Solution
Display name: Chlorpheniramine/Dextromethorphan/Phenylephrine (Oral Liquid)
Full name: chlorpheniramine maleate 0.8 MG/ML / dextromethorphan hydrobromide 3 MG/ML / phenylephrine hydrochloride 2 MG/ML Oral Solution
Term type: SCD
Status: Active
Strength: 4-15-10 mg/5ml
Dose form: Sol
Route: Oral Liquid
Updated: 2026-06-12 07:04:47

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 022011
Active start: 022011
Multiple ingredient: YES
Branded: NO

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
chlorpheniramine maleate	0.8 MG / 1 ML	chlorpheniramine	chlorpheniramine maleate
dextromethorphan hydrobromide	3 MG / 1 ML	dextromethorphan	dextromethorphan hydrobromide
phenylephrine hydrochloride	2 MG / 1 ML	phenylephrine	phenylephrine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Oral Solution	316968

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
chlorpheniramine	2400
dextromethorphan	3289
phenylephrine	8163

Source Vocabulary Codes#

Code type, Value, Category table
Code type	Value	Category
PRESCRIBABLE	Y	ATTRIBUTES
RXNAV_STR	chlorpheniramine maleate 0.8 MG/ML / dextromethorphan hydrobromide 3 MG/ML / phenylephrine hydrochloride 2 MG/ML Oral Solution	NAMES
RxNorm Name	chlorpheniramine maleate 0.8 MG/ML / dextromethorphan hydrobromide 3 MG/ML / phenylephrine hydrochloride 2 MG/ML Oral Solution	NAMES
RxNorm Synonym	chlorpheniramine maleate 4 MG / dextromethorphan hydrobromide 15 MG / phenylephrine hydrochloride 10 MG per 5 ML Oral Solution	NAMES
TTY	SCD	ATTRIBUTES
SPL_SET_ID	6aafe912-28ff-442f-8e07-b3c5993ac943	CODES
SPL_SET_ID	e0e2b117-62bc-4132-9f7c-fe2a912052b1	CODES
RxCUI	1086443	CODES
MMSL_CODE	BD8339	CODES
MMSL_CODE	CD8339	CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDC	Product NDC	Name	Labeler	Application
0485-0171-16	0485-0171	ED A-HIST DM DEXTROMETHORPHAN HYDROBROMIDE, CHLORPHENIRAMINE MALEATE, and PHENYLEPHRINE HYDROCHLORIDE	EDWARDS PHARMACEUTICALS, INC.	M012
68047-186-16	68047-186	NoHist DM Chlorpheniramine Maleate, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride	Larken Laboratories, Inc.	M012

Drugs@FDA Applications#

Application, NDC, Name table
Application	NDC	Name	Marketing category	Labeler
M012	0485-0171	ED A-HIST DM DEXTROMETHORPHAN HYDROBROMIDE, CHLORPHENIRAMINE MALEATE, and PHENYLEPHRINE HYDROCHLORIDE	OTC MONOGRAPH DRUG	EDWARDS PHARMACEUTICALS, INC.

RxNav Current And Historical NDCs#

NDC11, Source, Active table
NDC11	Source	Active
00485017116	rxnav_ndcs	yes
51991013116	rxnav_ndcs	yes
58605032116	rxnav_ndcs	yes
68047018616	rxnav_ndcs	yes
00485007116	rxnav_historical
00485007130	rxnav_historical
00677185233	rxnav_historical_indirect
45737021816	rxnav_historical
49963021001	rxnav_historical
49963021004	rxnav_historical
51301046016	rxnav_historical_indirect
51991009616	rxnav_historical_indirect
51991013141	rxnav_historical_indirect
52747041090	rxnav_historical
53163011416	rxnav_historical
55422007116	rxnav_historical_indirect
55654003201	rxnav_historical
55654003205	rxnav_historical
58118995804	rxnav_historical
58298042501	rxnav_historical_indirect
58298042516	rxnav_historical_indirect
58298042590	rxnav_historical_indirect
60258023816	rxnav_historical
60258052016	rxnav_historical_indirect
66739002316	rxnav_historical
68032016816	rxnav_historical

DailyMed RxNorm Mappings#

Set ID, RxNorm string, TTY table
Set ID	RxNorm string	TTY	SPL version	Label	Effective
6aafe912-28ff-442f-8e07-b3c5993ac943	chlorpheniramine maleate 4 MG / dextromethorphan hydrobromide 15 MG / phenylephrine hydrochloride 10 MG per 5 ML Oral Solution	SY	13	NoHist DM	20251016
6aafe912-28ff-442f-8e07-b3c5993ac943	chlorpheniramine maleate 0.8 MG/ML / dextromethorphan hydrobromide 3 MG/ML / phenylephrine hydrochloride 2 MG/ML Oral Solution	SCD	13	NoHist DM	20251016
6aafe912-28ff-442f-8e07-b3c5993ac943	chlorpheniramine maleate 4 MG / dextromethorphan HBr 15 MG / phenylephrine HCl 10 MG in 5 mL Oral Solution	PSN	13	NoHist DM	20251016
e0e2b117-62bc-4132-9f7c-fe2a912052b1	chlorpheniramine maleate 0.8 MG/ML / dextromethorphan hydrobromide 3 MG/ML / phenylephrine hydrochloride 2 MG/ML Oral Solution	SCD	10	ED-EDA-HISTDM 0171	20251231
e0e2b117-62bc-4132-9f7c-fe2a912052b1	chlorpheniramine maleate 4 MG / dextromethorphan HBr 15 MG / phenylephrine HCl 10 MG in 5 mL Oral Solution	PSN	10	ED-EDA-HISTDM 0171	20251231
e0e2b117-62bc-4132-9f7c-fe2a912052b1	chlorpheniramine maleate 4 MG / dextromethorphan hydrobromide 15 MG / phenylephrine hydrochloride 10 MG per 5 ML Oral Solution	SY	10	ED-EDA-HISTDM 0171	20251231
5488d81a-5a49-44f9-b16b-1cb55c35b175	chlorpheniramine maleate 4 MG / dextromethorphan HBr 15 MG / phenylephrine HCl 10 MG in 5 mL Oral Solution	PSN	1	Drug Facts	20100104
5488d81a-5a49-44f9-b16b-1cb55c35b175	chlorpheniramine maleate 0.8 MG/ML / dextromethorphan hydrobromide 3 MG/ML / phenylephrine hydrochloride 2 MG/ML Oral Solution	SCD	1	Drug Facts	20100104
5488d81a-5a49-44f9-b16b-1cb55c35b175	chlorpheniramine maleate 4 MG / dextromethorphan hydrobromide 15 MG / phenylephrine hydrochloride 10 MG per 5 ML Oral Solution	SY	1	Drug Facts	20100104

DailyMed Labels#

Set ID, Title, Manufacturer table
Set ID	Title	Manufacturer	Effective
e0e2b117-62bc-4132-9f7c-fe2a912052b1	ED-EDA-HISTDM 0171	EDWARDS PHARMACEUTICALS, INC.	20251231
6aafe912-28ff-442f-8e07-b3c5993ac943	NoHist DM	Larken Laboratories, Inc.	20251016
6aafe912-28ff-442f-8e07-b3c5993ac943	NoHist DM	Larken Laboratories, Inc.	20241011
5488d81a-5a49-44f9-b16b-1cb55c35b175	Drug Facts	Portal Pharmaceutical \| Elge Inc	20100104

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	C01CA	Adrenergic and dopaminergic agents	ATC1-4		phenylephrine
ATC	R05DA	Opium alkaloids and derivatives	ATC1-4		dextromethorphan
ATC	C05AX	Other agents for treatment of hemorrhoids and anal fissures for topical use	ATC1-4		phenylephrine
ATC	R06AB	Substituted alkylamines	ATC1-4		chlorpheniramine
ATC	R01BA	Sympathomimetics	ATC1-4		phenylephrine
ATC	S01FB	Sympathomimetics excl. antiglaucoma preparations	ATC1-4		phenylephrine
ATC	S01GA	Sympathomimetics used as decongestants	ATC1-4		phenylephrine
ATC	R01AB	Sympathomimetics, combinations excl. corticosteroids	ATC1-4		phenylephrine
ATC	R01AA	Sympathomimetics, plain	ATC1-4		phenylephrine
FDASPL	N0000186105	alpha-1 Adrenergic Agonist	EPC	has_epc	phenylephrine
FDASPL	N0000175587	Histamine-1 Receptor Antagonist	EPC	has_epc	chlorpheniramine
FDASPL	N0000182149	Sigma-1 Agonist	EPC	has_epc	dextromethorphan
FDASPL	N0000181821	Uncompetitive N-methyl-D-aspartate Receptor Antagonist	EPC	has_epc	dextromethorphan
FDASPL	N0000182147	Sigma-1 Receptor Agonists	MOA	has_moa	dextromethorphan
FDASPL	N0000181819	Uncompetitive NMDA Receptor Antagonists	MOA	has_moa	dextromethorphan
MEDRT	D002744	Chlorpheniramine	CHEM	has_ingredient	chlorpheniramine
MEDRT	D002744	Chlorpheniramine	CHEM	has_ingredient	chlorpheniramine maleate
MEDRT	D003915	Dextromethorphan	CHEM	has_ingredient	dextromethorphan hydrobromide
MEDRT	D003915	Dextromethorphan	CHEM	has_ingredient	dextromethorphan
MEDRT	D010656	Phenylephrine	CHEM	has_ingredient	phenylephrine
MEDRT	D010656	Phenylephrine	CHEM	has_ingredient	phenylephrine hydrochloride
MEDRT	D013447	Sulfites	CHEM	ci_chemclass	phenylephrine hydrochloride
MEDRT	D013447	Sulfites	CHEM	ci_chemclass	phenylephrine
MEDRT	D003371	Cough	DISEASE	may_treat	dextromethorphan
MEDRT	D003371	Cough	DISEASE	may_prevent	dextromethorphan
MEDRT	D003371	Cough	DISEASE	may_treat	dextromethorphan hydrobromide
MEDRT	D003371	Cough	DISEASE	may_prevent	dextromethorphan hydrobromide
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	chlorpheniramine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	dextromethorphan hydrobromide
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	phenylephrine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	dextromethorphan
MEDRT	D004380	Duodenal Obstruction	DISEASE	ci_with	chlorpheniramine
MEDRT	D004380	Duodenal Obstruction	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D005401	Fissure in Ano	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D005401	Fissure in Ano	DISEASE	may_treat	phenylephrine
MEDRT	D015812	Glaucoma, Angle-Closure	DISEASE	ci_with	chlorpheniramine
MEDRT	D015812	Glaucoma, Angle-Closure	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D005902	Glaucoma, Open-Angle	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D005902	Glaucoma, Open-Angle	DISEASE	may_treat	phenylephrine
MEDRT	D006484	Hemorrhoids	DISEASE	may_treat	phenylephrine
MEDRT	D006484	Hemorrhoids	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D006973	Hypertension	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D006973	Hypertension	DISEASE	ci_with	phenylephrine
MEDRT	D007022	Hypotension	DISEASE	may_treat	phenylephrine
MEDRT	D007022	Hypotension	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D007231	Infant, Newborn	DISEASE	ci_with	chlorpheniramine
MEDRT	D007231	Infant, Newborn	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D007234	Infant, Premature	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D007234	Infant, Premature	DISEASE	ci_with	chlorpheniramine
MEDRT	D015878	Mydriasis	DISEASE	induces	phenylephrine
MEDRT	D015878	Mydriasis	DISEASE	induces	phenylephrine hydrochloride
MEDRT	D010437	Peptic Ulcer	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D010437	Peptic Ulcer	DISEASE	ci_with	chlorpheniramine
MEDRT	D011470	Prostatic Hyperplasia	DISEASE	ci_with	chlorpheniramine
MEDRT	D011470	Prostatic Hyperplasia	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D011538	Pruritus Ani	DISEASE	may_treat	phenylephrine
MEDRT	D011538	Pruritus Ani	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	chlorpheniramine maleate
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	chlorpheniramine
MEDRT	D012223	Rhinitis, Vasomotor	DISEASE	may_treat	phenylephrine
MEDRT	D012223	Rhinitis, Vasomotor	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D012772	Shock, Septic	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D012772	Shock, Septic	DISEASE	may_treat	phenylephrine
MEDRT	D013224	Status Asthmaticus	DISEASE	ci_with	chlorpheniramine
MEDRT	D013224	Status Asthmaticus	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D013617	Tachycardia, Supraventricular	DISEASE	may_treat	phenylephrine
MEDRT	D013617	Tachycardia, Supraventricular	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	ci_with	phenylephrine
MEDRT	D001748	Urinary Bladder Neck Obstruction	DISEASE	ci_with	chlorpheniramine
MEDRT	D001748	Urinary Bladder Neck Obstruction	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D014581	Urticaria	DISEASE	may_treat	chlorpheniramine
MEDRT	D014581	Urticaria	DISEASE	may_treat	chlorpheniramine maleate
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	phenylephrine
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	phenylephrine hydrochloride
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	chlorpheniramine maleate
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	chlorpheniramine
MEDRT	N0000000184	Monoamine Oxidase Inhibitors	MOA	ci_moa	dextromethorphan hydrobromide
MEDRT	N0000000184	Monoamine Oxidase Inhibitors	MOA	ci_moa	dextromethorphan
MEDRT	N0000000109	Serotonin Uptake Inhibitors	MOA	has_moa	dextromethorphan hydrobromide
MEDRT	N0000000109	Serotonin Uptake Inhibitors	MOA	has_moa	dextromethorphan
MEDRT	N0000182147	Sigma-1 Receptor Agonists	MOA	has_moa	dextromethorphan
MEDRT	N0000182147	Sigma-1 Receptor Agonists	MOA	has_moa	dextromethorphan hydrobromide
MEDRT	N0000181819	Uncompetitive NMDA Receptor Antagonists	MOA	has_moa	dextromethorphan
MEDRT	N0000181819	Uncompetitive NMDA Receptor Antagonists	MOA	has_moa	dextromethorphan hydrobromide
MEDRT	N0000008371	Conjunctival Arterial Vasoconstriction	PE	has_pe	phenylephrine
MEDRT	N0000008371	Conjunctival Arterial Vasoconstriction	PE	has_pe	phenylephrine hydrochloride
MEDRT	N0000008657	Decreased Histamine Activity	PE	has_pe	chlorpheniramine maleate
MEDRT	N0000008657	Decreased Histamine Activity	PE	has_pe	chlorpheniramine
MEDRT	N0000008701	Decreased Medullary Respiratory Drive	PE	has_pe	dextromethorphan
MEDRT	N0000008701	Decreased Medullary Respiratory Drive	PE	has_pe	dextromethorphan hydrobromide
MEDRT	N0000008896	Decreased Nasal and Sinus Secretions	PE	has_pe	phenylephrine
MEDRT	N0000008896	Decreased Nasal and Sinus Secretions	PE	has_pe	phenylephrine hydrochloride

Group, Type, Concept table
Group	Type	Concept	Source
DF	DF	Oral Solution	rxnav_allrelated
DFG	DFG	Oral Liquid Product	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
IN	IN	chlorpheniramine	rxnav_allrelated
IN	IN	dextromethorphan	rxnav_allrelated
IN	IN	phenylephrine	rxnav_allrelated
MIN	MIN	chlorpheniramine / dextromethorphan / phenylephrine	rxnav_allrelated
PIN	PIN	chlorpheniramine maleate	rxnav_allrelated
PIN	PIN	dextromethorphan hydrobromide	rxnav_allrelated
PIN	PIN	phenylephrine hydrochloride	rxnav_allrelated
SCD	SCD	chlorpheniramine maleate 0.8 MG/ML / dextromethorphan hydrobromide 3 MG/ML / phenylephrine hydrochloride 2 MG/ML Oral Solution	rxnav_allrelated
SCDC	SCDC	chlorpheniramine maleate 0.8 MG/ML	rxnav_allrelated
SCDC	SCDC	dextromethorphan hydrobromide 3 MG/ML	rxnav_allrelated
SCDC	SCDC	phenylephrine hydrochloride 2 MG/ML	rxnav_allrelated
SCDF	SCDF	chlorpheniramine / dextromethorphan / phenylephrine Oral Solution	rxnav_allrelated
SCDFP	SCDFP	chlorpheniramine maleate / dextromethorphan hydrobromide / phenylephrine hydrochloride Oral Solution	rxnav_allrelated
SCDG	SCDG	chlorpheniramine / dextromethorphan / phenylephrine Oral Liquid Product	rxnav_allrelated
SCDG	SCDG	chlorpheniramine / dextromethorphan / phenylephrine Oral Product	rxnav_allrelated
SCDGP	SCDGP	chlorpheniramine maleate / dextromethorphan hydrobromide / phenylephrine hydrochloride Oral Liquid Product	rxnav_allrelated
SCDGP	SCDGP	chlorpheniramine maleate / dextromethorphan hydrobromide / phenylephrine hydrochloride Oral Product	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	0.8 MG/ML / 3 MG/ML / 2 MG/ML
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	PRESCRIBABLE	Y
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
ATTRIBUTES	SCHEDULE	0
ATTRIBUTES	TTY	SCD
CODES	MMSL_CODE	BD8339
CODES	MMSL_CODE	CD8339
CODES	RxCUI	1086443
CODES	SPL_SET_ID	6aafe912-28ff-442f-8e07-b3c5993ac943
CODES	SPL_SET_ID	e0e2b117-62bc-4132-9f7c-fe2a912052b1
CODES	VUID	4007313
NAMES	Prescribable Synonym	chlorpheniramine maleate 4 MG / dextromethorphan HBr 15 MG / phenylephrine HCl 10 MG in 5 mL Oral Solution
NAMES	RXNAV_STR	chlorpheniramine maleate 0.8 MG/ML / dextromethorphan hydrobromide 3 MG/ML / phenylephrine hydrochloride 2 MG/ML Oral Solution
NAMES	RxNorm Name	chlorpheniramine maleate 0.8 MG/ML / dextromethorphan hydrobromide 3 MG/ML / phenylephrine hydrochloride 2 MG/ML Oral Solution
NAMES	RxNorm Synonym	chlorpheniramine maleate 4 MG / dextromethorphan hydrobromide 15 MG / phenylephrine hydrochloride 10 MG per 5 ML Oral Solution
SOURCES	Source	Gold Standard Alchemy
SOURCES	Source	Metathesaurus FDA Structured Product Labels
SOURCES	Source	Micromedex RED BOOK
SOURCES	Source	Multum MediSource Lexicon
SOURCES	Source	National Drug Data File Plus Source Vocabulary
SOURCES	Source	Veterans Health Administration National Drug File

chlorpheniramine maleate 0.8 MG/ML / dextromethorphan hydrobromide 3 MG/ML / phenylephrine hydrochloride 2 MG/ML Oral Solution

RxNorm Status History#

Ingredients And Strength#

Dose Form Concepts#

Derived Ingredient Concepts#

Source Vocabulary Codes#

FDA NDC Products And Packages#

Drugs@FDA Applications#

RxNav Current And Historical NDCs#

DailyMed RxNorm Mappings#

DailyMed Labels#

Drug Classes#

Related Concepts#

Properties#