acetaminophen 500 MG / diphenhydramine hydrochloride 50 MG [Legatrin PM]
- RxCUI
- 1087608
- RxNorm name
- acetaminophen 500 MG / diphenhydramine hydrochloride 50 MG [Legatrin PM]
- Term type
- SBDC
- Status
- Active
- Updated
- 2026-07-22 07:06:47
RxNorm Status History#
- Status
- Active
- Source
- RXNORM
- Current
- YES
- Release start
- 022011
- Active start
- 022011
- Multiple ingredient
- YES
- Branded
- YES
Ingredients And Strength#
Ingredient, Strength, Base table| Ingredient | Strength | Base | Basis of strength |
|---|
| 500 MG / 1 EACH | acetaminophen | |
| 50 MG / 1 EACH | diphenhydramine | |
Derived Ingredient Concepts#
Drug Classes#
Source, Class ID, Class table| Source | Class ID | Class | Type | Relationship | Drug concept |
|---|
| ATC | R06AA | Aminoalkyl ethers | ATC1-4 | | diphenhydramine |
| ATC | N02BE | Anilides | ATC1-4 | | acetaminophen |
| ATC | D04AA | Antihistamines for topical use | ATC1-4 | | diphenhydramine |
| FDASPL | N0000175587 | Histamine-1 Receptor Antagonist | EPC | has_epc | diphenhydramine |
| FDASPL | N0000000190 | Histamine H1 Receptor Antagonists | MOA | has_moa | diphenhydramine |
| MEDRT | D000082 | Acetaminophen | CHEM | has_ingredient | acetaminophen |
| MEDRT | D004155 | Diphenhydramine | CHEM | has_ingredient | diphenhydramine hydrochloride |
| MEDRT | D004155 | Diphenhydramine | CHEM | has_ingredient | diphenhydramine |
| MEDRT | D001008 | Anxiety Disorders | DISEASE | may_treat | diphenhydramine |
| MEDRT | D001008 | Anxiety Disorders | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | acetaminophen |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | diphenhydramine |
| MEDRT | D005334 | Fever | DISEASE | may_prevent | acetaminophen |
| MEDRT | D005334 | Fever | DISEASE | may_treat | acetaminophen |
| MEDRT | D005955 | Glucosephosphate Dehydrogenase Deficiency | DISEASE | ci_with | acetaminophen |
| MEDRT | D007231 | Infant, Newborn | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D007231 | Infant, Newborn | DISEASE | ci_with | diphenhydramine |
| MEDRT | D007234 | Infant, Premature | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D007234 | Infant, Premature | DISEASE | ci_with | diphenhydramine |
| MEDRT | D007774 | Lactation | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D007774 | Lactation | DISEASE | ci_with | diphenhydramine |
| MEDRT | D008107 | Liver Diseases | DISEASE | ci_with | acetaminophen |
| MEDRT | D009041 | Motion Sickness | DISEASE | may_treat | diphenhydramine |
| MEDRT | D009041 | Motion Sickness | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D009325 | Nausea | DISEASE | may_treat | diphenhydramine |
| MEDRT | D009325 | Nausea | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D010146 | Pain | DISEASE | may_treat | acetaminophen |
| MEDRT | D010146 | Pain | DISEASE | may_prevent | acetaminophen |
| MEDRT | D012221 | Rhinitis, Allergic, Perennial | DISEASE | may_treat | diphenhydramine |
| MEDRT | D012221 | Rhinitis, Allergic, Perennial | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D007319 | Sleep Initiation and Maintenance Disorders | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D007319 | Sleep Initiation and Maintenance Disorders | DISEASE | may_treat | diphenhydramine |
| MEDRT | D012912 | Sneezing | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D012912 | Sneezing | DISEASE | may_treat | diphenhydramine |
| MEDRT | D013224 | Status Asthmaticus | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D013224 | Status Asthmaticus | DISEASE | ci_with | diphenhydramine |
| MEDRT | D014581 | Urticaria | DISEASE | may_treat | diphenhydramine |
| MEDRT | D014581 | Urticaria | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | N0000000190 | Histamine H1 Receptor Antagonists | MOA | has_moa | diphenhydramine hydrochloride |
| MEDRT | N0000000190 | Histamine H1 Receptor Antagonists | MOA | has_moa | diphenhydramine |
| MEDRT | N0000000108 | Prostaglandin Receptor Antagonists | MOA | has_moa | acetaminophen |
| MEDRT | N0000175724 | Central Nervous System Activity Alteration | PE | has_pe | acetaminophen |
| MEDRT | N0000008836 | Decreased Prostaglandin Production | PE | has_pe | acetaminophen |
| MEDRT | N0000009072 | Hypothalamic Endocrine Activity Alteration | PE | has_pe | acetaminophen |
| MEDRT | N0000175725 | Peripheral Nervous System Activity Alteration | PE | has_pe | acetaminophen |
| MEDRT | N0000000026 | Hepatic Metabolism | PK | has_pk | acetaminophen |
| MEDRT | N0000000042 | Renal Excretion | PK | has_pk | acetaminophen |
Properties#
Category, Property, Value table| Category | Property | Value |
|---|
| ATTRIBUTES | GENERAL_CARDINALITY | MULTI |
| ATTRIBUTES | PRESCRIBABLE | Y |
| ATTRIBUTES | RXNAV_HUMAN_DRUG | US |
| ATTRIBUTES | TTY | SBDC |
| CODES | RxCUI | 1087608 |
| NAMES | RXNAV_STR | acetaminophen 500 MG / diphenhydrAMINE hydrochloride 50 MG [Legatrin PM] |
| NAMES | RxNorm Name | acetaminophen 500 MG / diphenhydramine hydrochloride 50 MG [Legatrin PM] |
| NAMES | Tallman Synonym | acetaminophen 500 MG / diphenhydrAMINE hydrochloride 50 MG [Legatrin PM] |