FDA.reportPublic FDA data

acetaminophen 33.3 MG/ML / diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Tylenol PM]

RxCUI
1092375
RxNorm name
acetaminophen 33.3 MG/ML / diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Tylenol PM]
Display name
TYLENOL PM (Oral Liquid)
Full name
acetaminophen 33.3 MG/ML / diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Tylenol PM]
Term type
SBD
Status
Active
Strength
500-25 mg/15ml
Dose form
Sol
Route
Oral Liquid
Updated
2026-07-25 06:54:03

RxNorm Status History#

Status
Active
Source
RXNORM
Current
YES
Release start
042011
Active start
042011
Multiple ingredient
YES
Branded
YES

Ingredients And Strength#

Ingredient, Strength, Base table
IngredientStrengthBaseBasis of strength
acetaminophen33.3 MG / 1 MLacetaminophenacetaminophen
diphenhydramine hydrochloride1.67 MG / 1 MLdiphenhydraminediphenhydramine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose formRxCUI
Oral Solution316968

Derived Ingredient Concepts#

Ingredient, RxCUI table
IngredientRxCUI
acetaminophen161
diphenhydramine3498

Source Vocabulary Codes#

Code type, Value, Category table
Code typeValueCategory
PRESCRIBABLEYATTRIBUTES
RXNAV_STRAPAP 33.3 MG/ML / diphenhydrAMINE Hydrochloride 1.67 MG/ML Oral Solution [Tylenol PM]NAMES
RxNorm Nameacetaminophen 33.3 MG/ML / diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Tylenol PM]NAMES
RxNorm SynonymAPAP 33.3 MG/ML / Diphenhydramine Hydrochloride 1.67 MG/ML Oral Solution [Tylenol PM]NAMES
RxNorm SynonymTylenol PM (APAP 1000 MG / diphenhydramine hydrochloride 50 MG) per 30 ML Oral SolutionNAMES
RxNorm SynonymTylenol PM (APAP 500 MG / diphenhydramine hydrochloride 25 MG) per 15 ML Oral SolutionNAMES
TTYSBDATTRIBUTES
RxCUI1092375CODES
MMSL_CODEBD15194CODES

RxNav Current And Historical NDCs#

NDC11, Source, Active table
NDC11SourceActive
50580083301rxnav_ndcsyes
00045042108rxnav_historical
00045042716rxnav_historical
50580042708rxnav_historical
50580042716rxnav_historical

Drug Classes#

Source, Class ID, Class table
SourceClass IDClassTypeRelationshipDrug concept
ATCR06AAAminoalkyl ethersATC1-4diphenhydramine
ATCN02BEAnilidesATC1-4acetaminophen
ATCD04AAAntihistamines for topical useATC1-4diphenhydramine
FDASPLN0000175587Histamine-1 Receptor AntagonistEPChas_epcdiphenhydramine
FDASPLN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine
MEDRTD000082AcetaminophenCHEMhas_ingredientacetaminophen
MEDRTD004155DiphenhydramineCHEMhas_ingredientdiphenhydramine hydrochloride
MEDRTD004155DiphenhydramineCHEMhas_ingredientdiphenhydramine
MEDRTD001008Anxiety DisordersDISEASEmay_treatdiphenhydramine
MEDRTD001008Anxiety DisordersDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD004342Drug HypersensitivityDISEASEci_withdiphenhydramine hydrochloride
MEDRTD004342Drug HypersensitivityDISEASEci_withacetaminophen
MEDRTD004342Drug HypersensitivityDISEASEci_withdiphenhydramine
MEDRTD005334FeverDISEASEmay_preventacetaminophen
MEDRTD005334FeverDISEASEmay_treatacetaminophen
MEDRTD005955Glucosephosphate Dehydrogenase DeficiencyDISEASEci_withacetaminophen
MEDRTD007231Infant, NewbornDISEASEci_withdiphenhydramine hydrochloride
MEDRTD007231Infant, NewbornDISEASEci_withdiphenhydramine
MEDRTD007234Infant, PrematureDISEASEci_withdiphenhydramine hydrochloride
MEDRTD007234Infant, PrematureDISEASEci_withdiphenhydramine
MEDRTD007774LactationDISEASEci_withdiphenhydramine hydrochloride
MEDRTD007774LactationDISEASEci_withdiphenhydramine
MEDRTD008107Liver DiseasesDISEASEci_withacetaminophen
MEDRTD009041Motion SicknessDISEASEmay_treatdiphenhydramine
MEDRTD009041Motion SicknessDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD009325NauseaDISEASEmay_treatdiphenhydramine
MEDRTD009325NauseaDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD010146PainDISEASEmay_treatacetaminophen
MEDRTD010146PainDISEASEmay_preventacetaminophen
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatdiphenhydramine
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD007319Sleep Initiation and Maintenance DisordersDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD007319Sleep Initiation and Maintenance DisordersDISEASEmay_treatdiphenhydramine
MEDRTD012912SneezingDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD012912SneezingDISEASEmay_treatdiphenhydramine
MEDRTD013224Status AsthmaticusDISEASEci_withdiphenhydramine hydrochloride
MEDRTD013224Status AsthmaticusDISEASEci_withdiphenhydramine
MEDRTD014581UrticariaDISEASEmay_treatdiphenhydramine
MEDRTD014581UrticariaDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine hydrochloride
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine
MEDRTN0000000108Prostaglandin Receptor AntagonistsMOAhas_moaacetaminophen
MEDRTN0000175724Central Nervous System Activity AlterationPEhas_peacetaminophen
MEDRTN0000008836Decreased Prostaglandin ProductionPEhas_peacetaminophen
MEDRTN0000009072Hypothalamic Endocrine Activity AlterationPEhas_peacetaminophen
MEDRTN0000175725Peripheral Nervous System Activity AlterationPEhas_peacetaminophen
MEDRTN0000000026Hepatic MetabolismPKhas_pkacetaminophen
MEDRTN0000000042Renal ExcretionPKhas_pkacetaminophen

Properties#

Category, Property, Value table
CategoryPropertyValue
ATTRIBUTESAVAILABLE_STRENGTH33.3 MG/ML / 1.67 MG/ML
ATTRIBUTESGENERAL_CARDINALITYMULTI
ATTRIBUTESHUMAN_DRUGUS
ATTRIBUTESPRESCRIBABLEY
ATTRIBUTESRXNAV_HUMAN_DRUGUS
ATTRIBUTESSCHEDULE0
ATTRIBUTESTTYSBD
CODESMMSL_CODEBD15194
CODESRxCUI1092375
NAMESRXNAV_STRAPAP 33.3 MG/ML / diphenhydrAMINE Hydrochloride 1.67 MG/ML Oral Solution [Tylenol PM]
NAMESRxNorm Nameacetaminophen 33.3 MG/ML / diphenhydramine hydrochloride 1.67 MG/ML Oral Solution [Tylenol PM]
NAMESRxNorm SynonymAPAP 33.3 MG/ML / Diphenhydramine Hydrochloride 1.67 MG/ML Oral Solution [Tylenol PM]
NAMESRxNorm SynonymTylenol PM (APAP 1000 MG / diphenhydramine hydrochloride 50 MG) per 30 ML Oral Solution
NAMESRxNorm SynonymTylenol PM (APAP 500 MG / diphenhydramine hydrochloride 25 MG) per 15 ML Oral Solution
NAMESTallman Synonymacetaminophen 33.3 MG/ML / diphenhydrAMINE hydrochloride 1.67 MG/ML Oral Solution [Tylenol PM]
NAMESTallman SynonymAPAP 33.3 MG/ML / diphenhydrAMINE Hydrochloride 1.67 MG/ML Oral Solution [Tylenol PM]
NAMESTallman SynonymTylenol PM (APAP 1000 MG / diphenhydrAMINE hydrochloride 50 MG) per 30 ML Oral Solution
NAMESTallman SynonymTylenol PM (APAP 500 MG / diphenhydrAMINE hydrochloride 25 MG) per 15 ML Oral Solution
SOURCESSourceMultum MediSource Lexicon