acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet [Tylenol PM]

RxCUI: 1092378
RxNorm name: acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet [Tylenol PM]
Display name: TYLENOL PM (Oral Pill)
Full name: acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet [Tylenol PM]
Term type: SBD
Status: Active
Strength: 500-25 mg
Dose form: Tab
Route: Oral Pill
Updated: 2026-07-25 06:54:08

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 042011
Active start: 042011
Multiple ingredient: YES
Branded: YES

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
acetaminophen	500 MG / 1 EACH	acetaminophen	acetaminophen
diphenhydramine hydrochloride	25 MG / 1 EACH	diphenhydramine	diphenhydramine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Oral Tablet	317541

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
acetaminophen	161
diphenhydramine	3498

Source Vocabulary Codes#

Code type, Value, Category table
Code type	Value	Category
PRESCRIBABLE	Y	ATTRIBUTES
RXNAV_STR	APAP 500 MG / diphenhydrAMINE Hydrochloride 25 MG Oral Tablet [Tylenol PM]	NAMES
RxNorm Name	acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet [Tylenol PM]	NAMES
RxNorm Synonym	APAP 500 MG / Diphenhydramine Hydrochloride 25 MG Oral Tablet [Tylenol PM]	NAMES
RxNorm Synonym	Tylenol PM (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	NAMES
RxNorm Synonym	Tylenol PM Extra Strength (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	NAMES
TTY	SBD	ATTRIBUTES
SPL_SET_ID	435b1a31-353d-af20-e063-6294a90aa907	CODES
SPL_SET_ID	639f4e01-9723-a619-e053-2991aa0a549a	CODES
SPL_SET_ID	643371f2-e330-441e-8932-b3aec4b179d2	CODES
SPL_SET_ID	6cd07a01-7034-4994-bbd3-bedcdf7d5b83	CODES
SPL_SET_ID	83df6b68-8bb5-410b-bb97-0a5eecf424f2	CODES
SPL_SET_ID	8ed9a9f0-d37e-5c10-e053-2a95a90a559f	CODES
SPL_SET_ID	938c43f9-c8dd-48c1-a954-6e2c5f56562f	CODES
SPL_SET_ID	a40ea0e3-d666-4605-b5e0-beeaf8f586f2	CODES
SPL_SET_ID	ce58105b-f010-47af-8f31-6dd4ce4e9cba	CODES
RxCUI	1092378	CODES
MMSL_CODE	BD3997	CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDC	Product NDC	Name	Labeler	Application
50269-552-01	50269-552	Tylenol PM ACETAMINOPHEN, GUAIFENESIN, PHENYLEPHRINE HYDROCHLORIDE	JC World Bell Wholesale Co., Inc.	M013
50269-608-06	50269-608	Tylenol PM ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE	JC World Bell Wholesale Co., Inc.	M013
50580-608-01	50580-608	Tylenol PM acetaminophen and diphenhydramine hydrochloride	Kenvue Brands LLC	M013
50580-608-02	50580-608	Tylenol PM acetaminophen and diphenhydramine hydrochloride	Kenvue Brands LLC	M013
50580-608-03	50580-608	Tylenol PM acetaminophen and diphenhydramine hydrochloride	Kenvue Brands LLC	M013
50580-608-04	50580-608	Tylenol PM acetaminophen and diphenhydramine hydrochloride	Kenvue Brands LLC	M013
50580-608-05	50580-608	Tylenol PM acetaminophen and diphenhydramine hydrochloride	Kenvue Brands LLC	M013
50580-608-06	50580-608	Tylenol PM acetaminophen and diphenhydramine hydrochloride	Kenvue Brands LLC	M013
50580-608-07	50580-608	Tylenol PM acetaminophen and diphenhydramine hydrochloride	Kenvue Brands LLC	M013
50580-608-08	50580-608	Tylenol PM acetaminophen and diphenhydramine hydrochloride	Kenvue Brands LLC	M013
53209-1002-2	53209-1002	Tylenol PM acetaminophen and diphenhydramine hydrochloride	Morning Star OTC	M013
66715-6417-2	66715-6417	Tylenol PM Extra Strength, CVP HEALTH Acetaminophen and Diphenhydramine Hydrochloride	Lil' Drug Store Products, Inc.	M013
66715-6417-7	66715-6417	Tylenol PM Extra Strength, CVP HEALTH Acetaminophen and Diphenhydramine Hydrochloride	Lil' Drug Store Products, Inc.	M013
66715-6417-8	66715-6417	Tylenol PM Extra Strength, CVP HEALTH Acetaminophen and Diphenhydramine Hydrochloride	Lil' Drug Store Products, Inc.	M013
66715-6517-2	66715-6517	Tylenol PM Extra Strength, CVP HEALTH Acetaminophen and Diphenhydramine Hydrochloride	Lil' Drug Store Products, Inc.	M013
66715-9817-2	66715-9817	Lil Drug Store Tylenol PM Extra Strength Acetaminophen and Diphenhydramine Hydrochloride	Lil' Drug Store Products, Inc.	M013
66715-9817-3	66715-9817	Lil Drug Store Tylenol PM Extra Strength Acetaminophen and Diphenhydramine Hydrochloride	Lil' Drug Store Products, Inc.	M013
67414-608-00	67414-608	Tylenol PM ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE	Jones Healthcare Group - Packaging Services, Inc	M013
67414-608-06	67414-608	Tylenol PM ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE	Jones Healthcare Group - Packaging Services, Inc	M013
67751-241-01	67751-241	Tylenol PM acetaminophen and diphenhydramine hydrochloride	Navajo Manufacturing Company Inc.	M013
67751-241-02	67751-241	Tylenol PM acetaminophen and diphenhydramine hydrochloride	Navajo Manufacturing Company Inc.	M013
70264-028-01	70264-028	TYLENOL PM EXTRA STRENGTH ACETAMINOPHEN	R J General Corporation	M013
73097-013-02	73097-013	Tylenol PM ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE	Savings Distributors LLC	M013
73097-013-40	73097-013	Tylenol PM ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE	Savings Distributors LLC	M013
73097-013-50	73097-013	Tylenol PM ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE	Savings Distributors LLC	M013

Drugs@FDA Applications#

Application, NDC, Name table
Application	NDC	Name	Marketing category	Labeler
M013	50269-552	Tylenol PM ACETAMINOPHEN, GUAIFENESIN, PHENYLEPHRINE HYDROCHLORIDE	OTC MONOGRAPH DRUG	JC World Bell Wholesale Co., Inc.

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 119 matching rows.

NDC11, Source, Active table
NDC11	Source	Active
50269055201	rxnav_ndcs	yes
50269060806	rxnav_ndcs	yes
50580018220	rxnav_ndcs	yes
50580018240	rxnav_ndcs	yes
50580018252	rxnav_ndcs	yes
50580023424	rxnav_ndcs	yes
50580042610	rxnav_ndcs	yes
50580042623	rxnav_ndcs	yes
50580042624	rxnav_ndcs	yes
50580060801	rxnav_ndcs	yes
50580060802	rxnav_ndcs	yes
50580060803	rxnav_ndcs	yes
50580060804	rxnav_ndcs	yes
50580060805	rxnav_ndcs	yes
50580060806	rxnav_ndcs	yes
50580060807	rxnav_ndcs	yes
50580060808	rxnav_ndcs	yes
53209100201	rxnav_ndcs	yes
53209100202	rxnav_ndcs	yes
66715641702	rxnav_ndcs	yes
66715641707	rxnav_ndcs	yes
66715641708	rxnav_ndcs	yes
66715651702	rxnav_ndcs	yes
66715981702	rxnav_ndcs	yes
66715981703	rxnav_ndcs	yes
67414060800	rxnav_ndcs	yes
67414060806	rxnav_ndcs	yes
67751024101	rxnav_ndcs	yes
67751024102	rxnav_ndcs	yes
70264002801	rxnav_ndcs	yes
73097001302	rxnav_ndcs	yes
73097001340	rxnav_ndcs	yes
73097001350	rxnav_ndcs	yes
80850050610	rxnav_ndcs	yes
00045017610	rxnav_historical
00045017612	rxnav_historical
00045017615	rxnav_historical
00045017624	rxnav_historical
00045017650	rxnav_historical
00045017670	rxnav_historical
00045018210	rxnav_historical
00045018220	rxnav_historical_indirect
00045018240	rxnav_historical_indirect
00045024420	rxnav_historical
00045024440	rxnav_historical
00045024480	rxnav_historical
00045038250	rxnav_historical_indirect
00045048210	rxnav_historical
00045048211	rxnav_historical
00045048215	rxnav_historical
00045048216	rxnav_historical_indirect
00045048220	rxnav_historical
00045048224	rxnav_historical
00045048225	rxnav_historical
00045048235	rxnav_historical
00045048236	rxnav_historical
00045048250	rxnav_historical
00045048257	rxnav_historical
50580017601	rxnav_historical
50580017602	rxnav_historical
50580017604	rxnav_historical
50580017606	rxnav_historical
50580017608	rxnav_historical
50580017610	rxnav_historical
50580017612	rxnav_historical
50580017614	rxnav_historical
50580017615	rxnav_historical
50580017618	rxnav_historical
50580017619	rxnav_historical
50580017624	rxnav_historical
50580017640	rxnav_historical
50580017650	rxnav_historical
50580017665	rxnav_historical
50580017670	rxnav_historical
50580017674	rxnav_historical
50580024403	rxnav_historical
50580024408	rxnav_historical
50580024420	rxnav_historical
50580024440	rxnav_historical
50580024480	rxnav_historical
50580042606	rxnav_historical
50580042622	rxnav_historical
50580048204	rxnav_historical
50580048207	rxnav_historical
50580048209	rxnav_historical
50580048210	rxnav_historical
50580048211	rxnav_historical
50580048213	rxnav_historical
50580048215	rxnav_historical
50580048216	rxnav_historical
50580048217	rxnav_historical
50580048218	rxnav_historical
50580048222	rxnav_historical
50580048224	rxnav_historical
50580048225	rxnav_historical
50580048226	rxnav_historical
50580048230	rxnav_historical
50580048231	rxnav_historical
50580048232	rxnav_historical
50580048235	rxnav_historical
50580048236	rxnav_historical
50580048240	rxnav_historical
50580048245	rxnav_historical
50580048250	rxnav_historical
50580048265	rxnav_historical
50580048268	rxnav_historical
50580048270	rxnav_historical
50580050602	rxnav_historical
50580050603	rxnav_historical
50580050610	rxnav_historical
50580050624	rxnav_historical
50580050625	rxnav_historical
52904094504	rxnav_historical
52904094505	rxnav_historical
52904094520	rxnav_historical
52904094525	rxnav_historical
52904094550	rxnav_historical
67751016801	rxnav_historical
67751016802	rxnav_historical

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 10 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Tylenol PM Extra Strength	ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE	Kenvue Brands LLC	ce58105b-f010-47af-8f31-6dd4ce4e9cba	2026-07-22	Warnings	Exact identifier ndc (package): 50580-608-05 ndc (package): 50580-608-07 ndc (package): 50580-608-02 ndc (package): 50580-608-04 ndc (package): 50580-608-01 ndc (package): 50580-608-08 ndc (package): 50580-608-06 ndc (package): 50580-608-03 ndc (product): 50580-608 ndc11 (package): 50580060801 ndc11 (package): 50580060805 ndc11 (package): 50580060806 ndc11 (package): 50580060802 ndc11 (package): 50580060808 ndc11 (package): 50580060803 ndc11 (package): 50580060804 ndc11 (package): 50580060807 rxcui: 1092378
Tylenol PM Extra Strength	ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE	Select Consumer Group	55d0dceb-c9a9-778e-e063-6294a90a2ad7	2026-07-04	Warnings	Exact identifier rxcui: 1092378
Tylenol PM	ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE	Savings Distributors LLC	8ed9a9f0-d37e-5c10-e053-2a95a90a559f	2026-05-01	Warnings	Exact identifier ndc (package): 73097-013-02 ndc (package): 73097-013-40 ndc (package): 73097-013-50 ndc (product): 73097-013 ndc11 (package): 73097001340 ndc11 (package): 73097001350 ndc11 (package): 73097001302 rxcui: 1092378
Tylenol PM	ACETAMINOPHEN, GUAIFENESIN, PHENYLEPHRINE HYDROCHLORIDE	JC World Bell Wholesale Co., Inc.	938c43f9-c8dd-48c1-a954-6e2c5f56562f	2026-01-06	Warnings	Exact identifier ndc (package): 50269-552-01 ndc (product): 50269-552 ndc11 (package): 50269055201 rxcui: 1092378
Tylenol PM Extra Strength, CVP HEALTH	ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE	Lil' Drug Store Products, Inc.	643371f2-e330-441e-8932-b3aec4b179d2	2025-12-10	Warnings	Exact identifier ndc (package): 66715-6517-2 ndc (package): 66715-6417-8 ndc (package): 66715-9817-2 ndc (package): 66715-9817-3 ndc (package): 66715-6417-7 ndc (package): 66715-6417-2 ndc (product): 66715-6417 ndc (product): 66715-6517 ndc (product): 66715-9817 ndc11 (package): 66715981703 ndc11 (package): 66715641708 ndc11 (package): 66715981702 ndc11 (package): 66715641707 ndc11 (package): 66715651702 ndc11 (package): 66715641702 rxcui: 1092378
TYLENOL PM EXTRA STRENGTH	ACETAMINOPHEN	R J General Corporation	a40ea0e3-d666-4605-b5e0-beeaf8f586f2	2025-11-17	Warnings	Exact identifier ndc (package): 70264-028-01 ndc (product): 70264-028 ndc11 (package): 70264002801 rxcui: 1092378
Tylenol PM Extra Strength	ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE	Navajo Manufacturing Company Inc.	435b1a31-353d-af20-e063-6294a90aa907	2025-11-11	Warnings	Exact identifier ndc (package): 67751-241-01 ndc (package): 67751-241-02 ndc (product): 67751-241 ndc11 (package): 67751024101 ndc11 (package): 67751024102 rxcui: 1092378
Tylenol PM Extra Strength	ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE	Morning Star OTC	6cd07a01-7034-4994-bbd3-bedcdf7d5b83	2025-06-19	Warnings	Exact identifier ndc (package): 53209-1002-2 ndc (product): 53209-1002 ndc11 (package): 53209100202 ndc11 (package): 53209100201 rxcui: 1092378
Tylenol PM Extra Strength	ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE	Jones Healthcare Group - Packaging Services, Inc	639f4e01-9723-a619-e053-2991aa0a549a	2024-08-27	Warnings	Exact identifier ndc (package): 67414-608-06 ndc (package): 67414-608-00 ndc (product): 67414-608 ndc11 (package): 67414060806 ndc11 (package): 67414060800 rxcui: 1092378
Tylenol PM	ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE	JC World Bell Wholesale Co., Inc.	83df6b68-8bb5-410b-bb97-0a5eecf424f2	2023-11-08	Warnings	Exact identifier ndc (package): 50269-608-06 ndc (product): 50269-608 ndc11 (package): 50269060806 rxcui: 1092378

DailyMed RxNorm Mappings#

Set ID, RxNorm string, TTY table
Set ID	RxNorm string	TTY	SPL version	Label	Effective
ce58105b-f010-47af-8f31-6dd4ce4e9cba	Tylenol PM 500 MG / 25 MG Oral Tablet	PSN	13	Tylenol ® PM Extra Strength	20241101
ce58105b-f010-47af-8f31-6dd4ce4e9cba	Tylenol PM Extra Strength (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	13	Tylenol ® PM Extra Strength	20241101
ce58105b-f010-47af-8f31-6dd4ce4e9cba	Tylenol PM (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	13	Tylenol ® PM Extra Strength	20241101
ce58105b-f010-47af-8f31-6dd4ce4e9cba	APAP 500 MG / Diphenhydramine Hydrochloride 25 MG Oral Tablet [Tylenol PM]	SY	13	Tylenol ® PM Extra Strength	20241101
ce58105b-f010-47af-8f31-6dd4ce4e9cba	acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet [Tylenol PM]	SBD	13	Tylenol ® PM Extra Strength	20241101
643371f2-e330-441e-8932-b3aec4b179d2	Tylenol PM (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	11	Tylenol ® PM Extra Strength, Lil' Drug Store ® , CVP ® HEALTH, Travel BASIX	20251210
643371f2-e330-441e-8932-b3aec4b179d2	Tylenol PM Extra Strength (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	11	Tylenol ® PM Extra Strength, Lil' Drug Store ® , CVP ® HEALTH, Travel BASIX	20251210
643371f2-e330-441e-8932-b3aec4b179d2	APAP 500 MG / Diphenhydramine Hydrochloride 25 MG Oral Tablet [Tylenol PM]	SY	11	Tylenol ® PM Extra Strength, Lil' Drug Store ® , CVP ® HEALTH, Travel BASIX	20251210
643371f2-e330-441e-8932-b3aec4b179d2	Tylenol PM 500 MG / 25 MG Oral Tablet	PSN	11	Tylenol ® PM Extra Strength, Lil' Drug Store ® , CVP ® HEALTH, Travel BASIX	20251210
643371f2-e330-441e-8932-b3aec4b179d2	acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet [Tylenol PM]	SBD	11	Tylenol ® PM Extra Strength, Lil' Drug Store ® , CVP ® HEALTH, Travel BASIX	20251210
639f4e01-9723-a619-e053-2991aa0a549a	Tylenol PM Extra Strength (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	8	Tylenol PM Extra Stength	20240827
639f4e01-9723-a619-e053-2991aa0a549a	APAP 500 MG / Diphenhydramine Hydrochloride 25 MG Oral Tablet [Tylenol PM]	SY	8	Tylenol PM Extra Stength	20240827
639f4e01-9723-a619-e053-2991aa0a549a	Tylenol PM (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	8	Tylenol PM Extra Stength	20240827
639f4e01-9723-a619-e053-2991aa0a549a	Tylenol PM 500 MG / 25 MG Oral Tablet	PSN	8	Tylenol PM Extra Stength	20240827
639f4e01-9723-a619-e053-2991aa0a549a	acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet [Tylenol PM]	SBD	8	Tylenol PM Extra Stength	20240827
a40ea0e3-d666-4605-b5e0-beeaf8f586f2	Tylenol PM (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	4	TYLENOL ® PM EXTRA STRENGTH	20251117
a40ea0e3-d666-4605-b5e0-beeaf8f586f2	APAP 500 MG / Diphenhydramine Hydrochloride 25 MG Oral Tablet [Tylenol PM]	SY	4	TYLENOL ® PM EXTRA STRENGTH	20251117
a40ea0e3-d666-4605-b5e0-beeaf8f586f2	acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet [Tylenol PM]	SBD	4	TYLENOL ® PM EXTRA STRENGTH	20251117
a40ea0e3-d666-4605-b5e0-beeaf8f586f2	Tylenol PM Extra Strength (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	4	TYLENOL ® PM EXTRA STRENGTH	20251117
a40ea0e3-d666-4605-b5e0-beeaf8f586f2	Tylenol PM 500 MG / 25 MG Oral Tablet	PSN	4	TYLENOL ® PM EXTRA STRENGTH	20251117
8ed9a9f0-d37e-5c10-e053-2a95a90a559f	Tylenol PM (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	3	Tylenol PM	20260501
8ed9a9f0-d37e-5c10-e053-2a95a90a559f	Tylenol PM 500 MG / 25 MG Oral Tablet	PSN	3	Tylenol PM	20260501
8ed9a9f0-d37e-5c10-e053-2a95a90a559f	Tylenol PM Extra Strength (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	3	Tylenol PM	20260501
8ed9a9f0-d37e-5c10-e053-2a95a90a559f	APAP 500 MG / Diphenhydramine Hydrochloride 25 MG Oral Tablet [Tylenol PM]	SY	3	Tylenol PM	20260501
8ed9a9f0-d37e-5c10-e053-2a95a90a559f	acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet [Tylenol PM]	SBD	3	Tylenol PM	20260501
83df6b68-8bb5-410b-bb97-0a5eecf424f2	APAP 500 MG / Diphenhydramine Hydrochloride 25 MG Oral Tablet [Tylenol PM]	SY	3	Tylenol PM	20231108
83df6b68-8bb5-410b-bb97-0a5eecf424f2	Tylenol PM (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	3	Tylenol PM	20231108
83df6b68-8bb5-410b-bb97-0a5eecf424f2	acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet [Tylenol PM]	SBD	3	Tylenol PM	20231108
83df6b68-8bb5-410b-bb97-0a5eecf424f2	Tylenol PM Extra Strength (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	3	Tylenol PM	20231108
83df6b68-8bb5-410b-bb97-0a5eecf424f2	Tylenol PM 500 MG / 25 MG Oral Tablet	PSN	3	Tylenol PM	20231108
938c43f9-c8dd-48c1-a954-6e2c5f56562f	Tylenol PM (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	2	Tylenol PM	20260106
938c43f9-c8dd-48c1-a954-6e2c5f56562f	Tylenol PM Extra Strength (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	2	Tylenol PM	20260106
938c43f9-c8dd-48c1-a954-6e2c5f56562f	APAP 500 MG / Diphenhydramine Hydrochloride 25 MG Oral Tablet [Tylenol PM]	SY	2	Tylenol PM	20260106
938c43f9-c8dd-48c1-a954-6e2c5f56562f	acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet [Tylenol PM]	SBD	2	Tylenol PM	20260106
938c43f9-c8dd-48c1-a954-6e2c5f56562f	Tylenol PM 500 MG / 25 MG Oral Tablet	PSN	2	Tylenol PM	20260106
435b1a31-353d-af20-e063-6294a90aa907	Tylenol PM Extra Strength (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	1	Tylenol PM Extra Strength	20251111
435b1a31-353d-af20-e063-6294a90aa907	acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet [Tylenol PM]	SBD	1	Tylenol PM Extra Strength	20251111
435b1a31-353d-af20-e063-6294a90aa907	Tylenol PM (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	1	Tylenol PM Extra Strength	20251111
435b1a31-353d-af20-e063-6294a90aa907	APAP 500 MG / Diphenhydramine Hydrochloride 25 MG Oral Tablet [Tylenol PM]	SY	1	Tylenol PM Extra Strength	20251111
435b1a31-353d-af20-e063-6294a90aa907	Tylenol PM 500 MG / 25 MG Oral Tablet	PSN	1	Tylenol PM Extra Strength	20251111
6cd07a01-7034-4994-bbd3-bedcdf7d5b83	APAP 500 MG / Diphenhydramine Hydrochloride 25 MG Oral Tablet [Tylenol PM]	SY	1	Tylenol ® PM Extra Strength	20250619
6cd07a01-7034-4994-bbd3-bedcdf7d5b83	acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet [Tylenol PM]	SBD	1	Tylenol ® PM Extra Strength	20250619
6cd07a01-7034-4994-bbd3-bedcdf7d5b83	Tylenol PM (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	1	Tylenol ® PM Extra Strength	20250619
6cd07a01-7034-4994-bbd3-bedcdf7d5b83	Tylenol PM 500 MG / 25 MG Oral Tablet	PSN	1	Tylenol ® PM Extra Strength	20250619
6cd07a01-7034-4994-bbd3-bedcdf7d5b83	Tylenol PM Extra Strength (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	1	Tylenol ® PM Extra Strength	20250619
5b050993-334c-4118-865c-aae980b48aed	Tylenol PM (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	1	Tylenol ® PM	20220325
5b050993-334c-4118-865c-aae980b48aed	acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet [Tylenol PM]	SBD	1	Tylenol ® PM	20220325
5b050993-334c-4118-865c-aae980b48aed	Tylenol PM 500 MG / 25 MG Oral Tablet	PSN	1	Tylenol ® PM	20220325
5b050993-334c-4118-865c-aae980b48aed	Tylenol PM Extra Strength (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet	SY	1	Tylenol ® PM	20220325
5b050993-334c-4118-865c-aae980b48aed	APAP 500 MG / Diphenhydramine Hydrochloride 25 MG Oral Tablet [Tylenol PM]	SY	1	Tylenol ® PM	20220325

DailyMed Labels#

Set ID, Title, Manufacturer table
Set ID	Title	Manufacturer	Effective
ce58105b-f010-47af-8f31-6dd4ce4e9cba	Tylenol ® PM Extra Strength	Kenvue Brands LLC	20260722
ce58105b-f010-47af-8f31-6dd4ce4e9cba	Tylenol ® PM Extra Strength	Kenvue Brands LLC	20260609
8ed9a9f0-d37e-5c10-e053-2a95a90a559f	Tylenol PM	Savings Distributors LLC	20260501
938c43f9-c8dd-48c1-a954-6e2c5f56562f	Tylenol PM	JC World Bell Wholesale Co., Inc.	20260106
643371f2-e330-441e-8932-b3aec4b179d2	Tylenol ® PM Extra Strength, Lil' Drug Store ® , CVP ® HEALTH, Travel BASIX	Lil' Drug Store Products, Inc.	20251210
a40ea0e3-d666-4605-b5e0-beeaf8f586f2	TYLENOL ® PM EXTRA STRENGTH	R J General Corporation \| Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division	20251117
435b1a31-353d-af20-e063-6294a90aa907	Tylenol PM Extra Strength	Navajo Manufacturing Company Inc.	20251111
6cd07a01-7034-4994-bbd3-bedcdf7d5b83	Tylenol ® PM Extra Strength	Morning Star OTC	20250619
ce58105b-f010-47af-8f31-6dd4ce4e9cba	Tylenol ® PM Extra Strength	Kenvue Brands LLC	20241101
639f4e01-9723-a619-e053-2991aa0a549a	Tylenol PM Extra Stength	Jones Healthcare Group - Packaging Services, Inc \| McNeil Healthcare LLC.	20240827
83df6b68-8bb5-410b-bb97-0a5eecf424f2	Tylenol PM	JC World Bell Wholesale Co., Inc. \| McNeil Healthcare LLC	20231108
5b050993-334c-4118-865c-aae980b48aed	Tylenol ® PM	Select Corporation	20220325
a729cb7c-2845-4f37-85a1-97e459686e4d	Tylenol PM	Navajo Manufacturing Company Inc.	20201202
dadaacbc-e0ce-4c15-a1db-01ac40bcbf54		National Council for Prescription Drug Programs	20120724
d9d43f77-0d65-4b0f-b85d-b711987763b7		National Council for Prescription Drug Programs	20120724
f2bc2d1a-269a-4908-a674-b8eca903ab86		National Council for Prescription Drug Programs	20120724
dc71aa41-24d5-41bb-904e-35a6275c9ed1		National Council for Prescription Drug Programs	20120724
e1450b48-38a0-4eab-97ec-c6f52878638c		National Council for Prescription Drug Programs	20120724
05bc0ccd-9258-4a3e-a425-75c1ca5edbe4		National Council for Prescription Drug Programs	20120724
c11649a1-4007-4f0b-b3a6-a56346f49361		National Council for Prescription Drug Programs	20120724
b08b26b9-1613-4a42-b92d-a7e89633762c		National Council for Prescription Drug Programs	20120724
aa854535-3c5e-4b99-9681-9f414a835c47		National Council for Prescription Drug Programs	20120724
a5323666-d512-4dba-9347-cb63bba64930		National Council for Prescription Drug Programs	20120724
72187e1f-edb8-4c57-9f6c-567f4d605675		National Council for Prescription Drug Programs	20120724
5ae6a888-cdce-4398-9e32-41f5eb02bebe		National Council for Prescription Drug Programs	20120724
502276b4-4ad6-4c59-b3d3-693001d5c2a1		National Council for Prescription Drug Programs	20120724
33411294-3504-43bd-ac0c-565fb85a0d73		National Council for Prescription Drug Programs	20120724

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	R06AA	Aminoalkyl ethers	ATC1-4		diphenhydramine
ATC	N02BE	Anilides	ATC1-4		acetaminophen
ATC	D04AA	Antihistamines for topical use	ATC1-4		diphenhydramine
FDASPL	N0000175587	Histamine-1 Receptor Antagonist	EPC	has_epc	diphenhydramine
FDASPL	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	diphenhydramine
MEDRT	D000082	Acetaminophen	CHEM	has_ingredient	acetaminophen
MEDRT	D004155	Diphenhydramine	CHEM	has_ingredient	diphenhydramine hydrochloride
MEDRT	D004155	Diphenhydramine	CHEM	has_ingredient	diphenhydramine
MEDRT	D001008	Anxiety Disorders	DISEASE	may_treat	diphenhydramine
MEDRT	D001008	Anxiety Disorders	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	acetaminophen
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	diphenhydramine
MEDRT	D005334	Fever	DISEASE	may_prevent	acetaminophen
MEDRT	D005334	Fever	DISEASE	may_treat	acetaminophen
MEDRT	D005955	Glucosephosphate Dehydrogenase Deficiency	DISEASE	ci_with	acetaminophen
MEDRT	D007231	Infant, Newborn	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D007231	Infant, Newborn	DISEASE	ci_with	diphenhydramine
MEDRT	D007234	Infant, Premature	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D007234	Infant, Premature	DISEASE	ci_with	diphenhydramine
MEDRT	D007774	Lactation	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D007774	Lactation	DISEASE	ci_with	diphenhydramine
MEDRT	D008107	Liver Diseases	DISEASE	ci_with	acetaminophen
MEDRT	D009041	Motion Sickness	DISEASE	may_treat	diphenhydramine
MEDRT	D009041	Motion Sickness	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D009325	Nausea	DISEASE	may_treat	diphenhydramine
MEDRT	D009325	Nausea	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D010146	Pain	DISEASE	may_treat	acetaminophen
MEDRT	D010146	Pain	DISEASE	may_prevent	acetaminophen
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	diphenhydramine
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D007319	Sleep Initiation and Maintenance Disorders	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D007319	Sleep Initiation and Maintenance Disorders	DISEASE	may_treat	diphenhydramine
MEDRT	D012912	Sneezing	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D012912	Sneezing	DISEASE	may_treat	diphenhydramine
MEDRT	D013224	Status Asthmaticus	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D013224	Status Asthmaticus	DISEASE	ci_with	diphenhydramine
MEDRT	D014581	Urticaria	DISEASE	may_treat	diphenhydramine
MEDRT	D014581	Urticaria	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	diphenhydramine hydrochloride
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	diphenhydramine
MEDRT	N0000000108	Prostaglandin Receptor Antagonists	MOA	has_moa	acetaminophen
MEDRT	N0000175724	Central Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000008836	Decreased Prostaglandin Production	PE	has_pe	acetaminophen
MEDRT	N0000009072	Hypothalamic Endocrine Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000175725	Peripheral Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000000026	Hepatic Metabolism	PK	has_pk	acetaminophen
MEDRT	N0000000042	Renal Excretion	PK	has_pk	acetaminophen

Group, Type, Concept table
Group	Type	Concept	Source
BN	BN	Tylenol PM	rxnav_allrelated
DF	DF	Oral Tablet	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
DFG	DFG	Pill	rxnav_allrelated
IN	IN	acetaminophen	rxnav_allrelated
IN	IN	diphenhydramine	rxnav_allrelated
MIN	MIN	acetaminophen / diphenhydramine	rxnav_allrelated
PIN	PIN	diphenhydramine hydrochloride	rxnav_allrelated
SBD	SBD	acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet [Tylenol PM]	rxnav_allrelated
SBDC	SBDC	acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG [Tylenol PM]	rxnav_allrelated
SBDF	SBDF	acetaminophen / diphenhydramine Oral Tablet [Tylenol PM]	rxnav_allrelated
SBDFP	SBDFP	acetaminophen / diphenhydramine hydrochloride Oral Tablet [Tylenol PM]	rxnav_allrelated
SBDG	SBDG	Tylenol PM Oral Product	rxnav_allrelated
SBDG	SBDG	Tylenol PM Pill	rxnav_allrelated
SCD	SCD	acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet	rxnav_allrelated
SCDC	SCDC	acetaminophen 500 MG	rxnav_allrelated
SCDC	SCDC	diphenhydramine hydrochloride 25 MG	rxnav_allrelated
SCDF	SCDF	acetaminophen / diphenhydramine Oral Tablet	rxnav_allrelated
SCDFP	SCDFP	acetaminophen / diphenhydramine hydrochloride Oral Tablet	rxnav_allrelated
SCDG	SCDG	acetaminophen / diphenhydramine Oral Product	rxnav_allrelated
SCDG	SCDG	acetaminophen / diphenhydramine Pill	rxnav_allrelated
SCDGP	SCDGP	acetaminophen / diphenhydramine hydrochloride Oral Product	rxnav_allrelated
SCDGP	SCDGP	acetaminophen / diphenhydramine hydrochloride Pill	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	500 MG / 25 MG
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	PRESCRIBABLE	Y
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
ATTRIBUTES	SCHEDULE	0
ATTRIBUTES	TTY	SBD
CODES	MMSL_CODE	BD3997
CODES	RxCUI	1092378
CODES	SPL_SET_ID	435b1a31-353d-af20-e063-6294a90aa907
CODES	SPL_SET_ID	639f4e01-9723-a619-e053-2991aa0a549a
CODES	SPL_SET_ID	643371f2-e330-441e-8932-b3aec4b179d2
CODES	SPL_SET_ID	6cd07a01-7034-4994-bbd3-bedcdf7d5b83
CODES	SPL_SET_ID	83df6b68-8bb5-410b-bb97-0a5eecf424f2
CODES	SPL_SET_ID	8ed9a9f0-d37e-5c10-e053-2a95a90a559f
CODES	SPL_SET_ID	938c43f9-c8dd-48c1-a954-6e2c5f56562f
CODES	SPL_SET_ID	a40ea0e3-d666-4605-b5e0-beeaf8f586f2
CODES	SPL_SET_ID	ce58105b-f010-47af-8f31-6dd4ce4e9cba
NAMES	Prescribable Synonym	Tylenol PM 500 MG / 25 MG Oral Tablet
NAMES	RXNAV_STR	APAP 500 MG / diphenhydrAMINE Hydrochloride 25 MG Oral Tablet [Tylenol PM]
NAMES	RxNorm Name	acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG Oral Tablet [Tylenol PM]
NAMES	RxNorm Synonym	APAP 500 MG / Diphenhydramine Hydrochloride 25 MG Oral Tablet [Tylenol PM]
NAMES	RxNorm Synonym	Tylenol PM (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet
NAMES	RxNorm Synonym	Tylenol PM Extra Strength (APAP 500 MG / diphenhydramine hydrochloride 25 MG) Oral Tablet
NAMES	Tallman Synonym	acetaminophen 500 MG / diphenhydrAMINE hydrochloride 25 MG Oral Tablet [Tylenol PM]
NAMES	Tallman Synonym	APAP 500 MG / diphenhydrAMINE Hydrochloride 25 MG Oral Tablet [Tylenol PM]
NAMES	Tallman Synonym	Tylenol PM (APAP 500 MG / diphenhydrAMINE hydrochloride 25 MG) Oral Tablet
NAMES	Tallman Synonym	Tylenol PM Extra Strength (APAP 500 MG / diphenhydrAMINE hydrochloride 25 MG) Oral Tablet
SOURCES	Source	Gold Standard Alchemy
SOURCES	Source	Metathesaurus FDA Structured Product Labels
SOURCES	Source	Micromedex RED BOOK
SOURCES	Source	Multum MediSource Lexicon