acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet

RxCUI: 1098496
RxNorm name: acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet
Display name: Acetaminophen/Chlorpheniramine/Dextromethorphan (Oral Pill)
Full name: acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet
Term type: SCD
Status: Active
Strength: 500-2-15 mg
Dose form: Tab
Route: Oral Pill
Updated: 2026-06-15 07:02:09

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 052011
Active start: 052011
Multiple ingredient: YES
Branded: NO

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
acetaminophen	500 MG / 1 EACH	acetaminophen	acetaminophen
chlorpheniramine maleate	2 MG / 1 EACH	chlorpheniramine	chlorpheniramine maleate
dextromethorphan hydrobromide	15 MG / 1 EACH	dextromethorphan	dextromethorphan hydrobromide

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Oral Tablet	317541

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
acetaminophen	161
chlorpheniramine	2400
dextromethorphan	3289

Source Vocabulary Codes#

Code type, Value, Category table
Code type	Value	Category
PRESCRIBABLE	Y	ATTRIBUTES
RXNAV_STR	acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet	NAMES
RxNorm Name	acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet	NAMES
RxNorm Synonym	APAP 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet	NAMES
TTY	SCD	ATTRIBUTES
SPL_SET_ID	19ad2cca-c1cb-019c-e063-6294a90a5644	CODES
SPL_SET_ID	31aa77e0-cfdb-57a8-e063-6394a90af98c	CODES
SPL_SET_ID	3417993d-8e3c-23d6-e063-6394a90a7d50	CODES
SPL_SET_ID	68d3e88a-d1be-410b-92a1-863903b3aa61	CODES
SPL_SET_ID	e33f2319-2181-46db-a094-3e874b324c0a	CODES
RxCUI	1098496	CODES
MMSL_CODE	BD12971	CODES
MMSL_CODE	CD12971	CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDC	Product NDC	Name	Labeler	Application
0135-7034-20	0135-7034	Panadol acetaminophen, chlorpheniramine maleate, dextromethorphan HBr	Haleon US Holdings LLC	M012

Drugs@FDA Applications#

Application, NDC, Name table
Application	NDC	Name	Marketing category	Labeler
M012	0135-7034	Panadol acetaminophen, chlorpheniramine maleate, dextromethorphan HBr	OTC MONOGRAPH DRUG	Haleon US Holdings LLC

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 20 matching rows.

NDC11, Source, Active table
NDC11	Source	Active
00067816301	rxnav_ndcs	yes
00135703420	rxnav_ndcs	yes
00363046109	rxnav_ndcs	yes
11523130502	rxnav_ndcs	yes
11523411101	rxnav_ndcs	yes
41100057463	rxnav_ndcs	yes
51316045101	rxnav_ndcs	yes
59779046109	rxnav_ndcs	yes
00067298180	rxnav_historical
11523130501	rxnav_historical
11822042200	rxnav_historical
11822046109	rxnav_historical
11822461009	rxnav_historical
11917007635	rxnav_historical
15127095820	rxnav_historical
41250086109	rxnav_historical
55910046103	rxnav_historical
63868014220	rxnav_historical
70000013801	rxnav_historical
76000046108	rxnav_historical

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Panadol Cold and Flu Night	ACETAMINOPHEN, CHLORPHENIRAMINE MALEATE, DEXTROMETHORPHAN HBR	Haleon US Holdings LLC	3417993d-8e3c-23d6-e063-6394a90a7d50	2026-04-29	Warnings	Exact identifier ndc (package): 0135-7034-20 ndc (product): 0135-7034 ndc11 (package): 00135703420 rxcui: 1098496
Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan HBr	ACETAMINOPHEN, CHLORPHENIRAMINE MALEATE, DEXTROMETHORPHAN HBR	CVS Pharmacy, Inc	31aa77e0-cfdb-57a8-e063-6394a90af98c	2025-09-04	Warnings	Exact identifier ndc11 (package): 51316045101 rxcui: 1098496
EXTRA STRENGTH TYLENOL SEVERE COUGH PLUS SORE THROAT DAY/NIGHT	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, CHLORPHENIRAMINE MALEATE	Kenvue Brands LLC	19ad2cca-c1cb-019c-e063-6294a90a5644	2025-07-16	Warnings	Exact identifier rxcui: 1098496
Theraflu Flu Relief Maximum Strength Daytime Nighttime Combo Pack	ACETAMINOPHEN, DEXTROMETHORPHAN HBR AND ACETAMINOPHEN, CHLORPHENIRAMINE MALEATE, DEXTROMETHORPHAN HBR	Haleon US Holdings LLC	68d3e88a-d1be-410b-92a1-863903b3aa61	2024-03-08	Warnings	Exact identifier ndc11 (package): 00067816301 rxcui: 1098496

DailyMed RxNorm Mappings#

Set ID, RxNorm string, TTY table
Set ID	RxNorm string	TTY	SPL version	Label	Effective
e33f2319-2181-46db-a094-3e874b324c0a	acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan HBr 15 MG Oral Tablet	PSN	6	Coricidin HBP Day and Night Multi-Symptom Cold	20251205
e33f2319-2181-46db-a094-3e874b324c0a	APAP 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet	SY	6	Coricidin HBP Day and Night Multi-Symptom Cold	20251205
e33f2319-2181-46db-a094-3e874b324c0a	acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet	SCD	6	Coricidin HBP Day and Night Multi-Symptom Cold	20251205
19ad2cca-c1cb-019c-e063-6294a90a5644	acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet	SCD	4	EXTRA STRENGTH TYLENOL® SEVERE COUGH + SORE THROAT DAY/NIGHT	20250716
19ad2cca-c1cb-019c-e063-6294a90a5644	APAP 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet	SY	4	EXTRA STRENGTH TYLENOL® SEVERE COUGH + SORE THROAT DAY/NIGHT	20250716
19ad2cca-c1cb-019c-e063-6294a90a5644	acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan HBr 15 MG Oral Tablet	PSN	4	EXTRA STRENGTH TYLENOL® SEVERE COUGH + SORE THROAT DAY/NIGHT	20250716
68d3e88a-d1be-410b-92a1-863903b3aa61	APAP 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet	SY	3	Drug Facts	20240308
68d3e88a-d1be-410b-92a1-863903b3aa61	acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet	SCD	3	Drug Facts	20240308
68d3e88a-d1be-410b-92a1-863903b3aa61	acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan HBr 15 MG Oral Tablet	PSN	3	Drug Facts	20240308
3417993d-8e3c-23d6-e063-6394a90a7d50	acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet	SCD	2	Drug Facts	20260429
3417993d-8e3c-23d6-e063-6394a90a7d50	APAP 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet	SY	2	Drug Facts	20260429
3417993d-8e3c-23d6-e063-6394a90a7d50	acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan HBr 15 MG Oral Tablet	PSN	2	Drug Facts	20260429
31aa77e0-cfdb-57a8-e063-6394a90af98c	acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan HBr 15 MG Oral Tablet	PSN	2	6044-CVS	20250904
31aa77e0-cfdb-57a8-e063-6394a90af98c	APAP 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet	SY	2	6044-CVS	20250904
31aa77e0-cfdb-57a8-e063-6394a90af98c	acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet	SCD	2	6044-CVS	20250904

DailyMed Labels#

Set ID, Title, Manufacturer table
Set ID	Title	Manufacturer	Effective
3417993d-8e3c-23d6-e063-6394a90a7d50	Drug Facts	Haleon US Holdings LLC	20260429
e33f2319-2181-46db-a094-3e874b324c0a	Coricidin HBP Day and Night Multi-Symptom Cold	Bayer HealthCare LLC.	20251205
31aa77e0-cfdb-57a8-e063-6394a90af98c	6044-CVS	CVS Pharmacy, Inc	20250904
68d3e88a-d1be-410b-92a1-863903b3aa61	Drug Facts	Haleon US Holdings LLC	20240308
d7f148ae-b7a0-495f-af6e-3895c998fd48	Meijer 44-461	Meijer Distribution Inc \| LNK International, Inc.	20210714
29015d7c-60f8-4492-a821-05d05faffbdb	Walgreens 44-461-Delisted	Walgreen Company \| LNK International, Inc.	20210607
3fcb4b21-ec8a-205f-980e-d5fdabb43acd	CVS 44-461-Delisted	CVS Pharmacy \| LNK International, Inc.	20201028
f0aa2bcd-66b5-45c8-b599-05894d0d2e59	Quality Choice 44-461	CHAIN DRUG MARKETING ASSOCIATION INC \| LNK International, Inc.	20201027
3e9db7f3-dcfa-4d96-a71d-e0085bf81118	Leader 44-461-Delisted	Cardinal Health \| LNK International, Inc.	20201027
7f4be634-d25d-4591-adf4-7ed3eb8279c4	Rite Aid 44-461 Delisted	Rite Aid Corporation \| LNK International, Inc.	20200526
355f86cc-e222-45cb-87da-28718c83b413		National Council for Prescription Drug Programs	20120724
babdbe4e-a14c-4ddd-a93b-7ac4f54a10b7	Rite Aid 44-461	Rite Aid	20110808

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	N02BE	Anilides	ATC1-4		acetaminophen
ATC	R05DA	Opium alkaloids and derivatives	ATC1-4		dextromethorphan
ATC	R06AB	Substituted alkylamines	ATC1-4		chlorpheniramine
FDASPL	N0000175587	Histamine-1 Receptor Antagonist	EPC	has_epc	chlorpheniramine
FDASPL	N0000182149	Sigma-1 Agonist	EPC	has_epc	dextromethorphan
FDASPL	N0000181821	Uncompetitive N-methyl-D-aspartate Receptor Antagonist	EPC	has_epc	dextromethorphan
FDASPL	N0000182147	Sigma-1 Receptor Agonists	MOA	has_moa	dextromethorphan
FDASPL	N0000181819	Uncompetitive NMDA Receptor Antagonists	MOA	has_moa	dextromethorphan
MEDRT	D000082	Acetaminophen	CHEM	has_ingredient	acetaminophen
MEDRT	D002744	Chlorpheniramine	CHEM	has_ingredient	chlorpheniramine maleate
MEDRT	D002744	Chlorpheniramine	CHEM	has_ingredient	chlorpheniramine
MEDRT	D003915	Dextromethorphan	CHEM	has_ingredient	dextromethorphan hydrobromide
MEDRT	D003915	Dextromethorphan	CHEM	has_ingredient	dextromethorphan
MEDRT	D003371	Cough	DISEASE	may_treat	dextromethorphan hydrobromide
MEDRT	D003371	Cough	DISEASE	may_treat	dextromethorphan
MEDRT	D003371	Cough	DISEASE	may_prevent	dextromethorphan
MEDRT	D003371	Cough	DISEASE	may_prevent	dextromethorphan hydrobromide
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	dextromethorphan hydrobromide
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	dextromethorphan
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	chlorpheniramine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	acetaminophen
MEDRT	D004380	Duodenal Obstruction	DISEASE	ci_with	chlorpheniramine
MEDRT	D004380	Duodenal Obstruction	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D005334	Fever	DISEASE	may_prevent	acetaminophen
MEDRT	D005334	Fever	DISEASE	may_treat	acetaminophen
MEDRT	D015812	Glaucoma, Angle-Closure	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D015812	Glaucoma, Angle-Closure	DISEASE	ci_with	chlorpheniramine
MEDRT	D005955	Glucosephosphate Dehydrogenase Deficiency	DISEASE	ci_with	acetaminophen
MEDRT	D007231	Infant, Newborn	DISEASE	ci_with	chlorpheniramine
MEDRT	D007231	Infant, Newborn	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D007234	Infant, Premature	DISEASE	ci_with	chlorpheniramine
MEDRT	D007234	Infant, Premature	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D008107	Liver Diseases	DISEASE	ci_with	acetaminophen
MEDRT	D010146	Pain	DISEASE	may_prevent	acetaminophen
MEDRT	D010146	Pain	DISEASE	may_treat	acetaminophen
MEDRT	D010437	Peptic Ulcer	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D010437	Peptic Ulcer	DISEASE	ci_with	chlorpheniramine
MEDRT	D011470	Prostatic Hyperplasia	DISEASE	ci_with	chlorpheniramine
MEDRT	D011470	Prostatic Hyperplasia	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	chlorpheniramine maleate
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	chlorpheniramine
MEDRT	D013224	Status Asthmaticus	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D013224	Status Asthmaticus	DISEASE	ci_with	chlorpheniramine
MEDRT	D001748	Urinary Bladder Neck Obstruction	DISEASE	ci_with	chlorpheniramine
MEDRT	D001748	Urinary Bladder Neck Obstruction	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D014581	Urticaria	DISEASE	may_treat	chlorpheniramine maleate
MEDRT	D014581	Urticaria	DISEASE	may_treat	chlorpheniramine
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	chlorpheniramine maleate
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	chlorpheniramine
MEDRT	N0000000184	Monoamine Oxidase Inhibitors	MOA	ci_moa	dextromethorphan
MEDRT	N0000000184	Monoamine Oxidase Inhibitors	MOA	ci_moa	dextromethorphan hydrobromide
MEDRT	N0000000108	Prostaglandin Receptor Antagonists	MOA	has_moa	acetaminophen
MEDRT	N0000000109	Serotonin Uptake Inhibitors	MOA	has_moa	dextromethorphan hydrobromide
MEDRT	N0000000109	Serotonin Uptake Inhibitors	MOA	has_moa	dextromethorphan
MEDRT	N0000182147	Sigma-1 Receptor Agonists	MOA	has_moa	dextromethorphan
MEDRT	N0000182147	Sigma-1 Receptor Agonists	MOA	has_moa	dextromethorphan hydrobromide
MEDRT	N0000181819	Uncompetitive NMDA Receptor Antagonists	MOA	has_moa	dextromethorphan
MEDRT	N0000181819	Uncompetitive NMDA Receptor Antagonists	MOA	has_moa	dextromethorphan hydrobromide
MEDRT	N0000175724	Central Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000008657	Decreased Histamine Activity	PE	has_pe	chlorpheniramine maleate
MEDRT	N0000008657	Decreased Histamine Activity	PE	has_pe	chlorpheniramine
MEDRT	N0000008701	Decreased Medullary Respiratory Drive	PE	has_pe	dextromethorphan
MEDRT	N0000008701	Decreased Medullary Respiratory Drive	PE	has_pe	dextromethorphan hydrobromide
MEDRT	N0000008836	Decreased Prostaglandin Production	PE	has_pe	acetaminophen
MEDRT	N0000009072	Hypothalamic Endocrine Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000175725	Peripheral Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000000026	Hepatic Metabolism	PK	has_pk	acetaminophen
MEDRT	N0000000042	Renal Excretion	PK	has_pk	acetaminophen

Group, Type, Concept table
Group	Type	Concept	Source
DF	DF	Oral Tablet	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
DFG	DFG	Pill	rxnav_allrelated
GPCK	GPCK	{1 (acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet) / 1 (acetaminophen 500 MG / dextromethorphan hydrobromide 15 MG Oral Tablet) } Pack	rxnav_allrelated
GPCK	GPCK	{1 (acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet) / 1 (dextromethorphan hydrobromide 10 MG / guaifenesin 200 MG Oral Capsule) } Pack	rxnav_allrelated
IN	IN	acetaminophen	rxnav_allrelated
IN	IN	chlorpheniramine	rxnav_allrelated
IN	IN	dextromethorphan	rxnav_allrelated
MIN	MIN	acetaminophen / chlorpheniramine / dextromethorphan	rxnav_allrelated
PIN	PIN	chlorpheniramine maleate	rxnav_allrelated
PIN	PIN	dextromethorphan hydrobromide	rxnav_allrelated
SCD	SCD	acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet	rxnav_allrelated
SCDC	SCDC	acetaminophen 500 MG	rxnav_allrelated
SCDC	SCDC	chlorpheniramine maleate 2 MG	rxnav_allrelated
SCDC	SCDC	dextromethorphan hydrobromide 15 MG	rxnav_allrelated
SCDF	SCDF	acetaminophen / chlorpheniramine / dextromethorphan Oral Tablet	rxnav_allrelated
SCDFP	SCDFP	acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide Oral Tablet	rxnav_allrelated
SCDG	SCDG	acetaminophen / chlorpheniramine / dextromethorphan Oral Product	rxnav_allrelated
SCDG	SCDG	acetaminophen / chlorpheniramine / dextromethorphan Pill	rxnav_allrelated
SCDGP	SCDGP	acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide Oral Product	rxnav_allrelated
SCDGP	SCDGP	acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide Pill	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	500 MG / 2 MG / 15 MG
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	PRESCRIBABLE	Y
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
ATTRIBUTES	SCHEDULE	0
ATTRIBUTES	TTY	SCD
CODES	MMSL_CODE	BD12971
CODES	MMSL_CODE	CD12971
CODES	RxCUI	1098496
CODES	SPL_SET_ID	19ad2cca-c1cb-019c-e063-6294a90a5644
CODES	SPL_SET_ID	31aa77e0-cfdb-57a8-e063-6394a90af98c
CODES	SPL_SET_ID	3417993d-8e3c-23d6-e063-6394a90a7d50
CODES	SPL_SET_ID	68d3e88a-d1be-410b-92a1-863903b3aa61
CODES	SPL_SET_ID	e33f2319-2181-46db-a094-3e874b324c0a
CODES	VUID	4030791
NAMES	Prescribable Synonym	acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan HBr 15 MG Oral Tablet
NAMES	RXNAV_STR	acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet
NAMES	RxNorm Name	acetaminophen 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet
NAMES	RxNorm Synonym	APAP 500 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 15 MG Oral Tablet
SOURCES	Source	Gold Standard Alchemy
SOURCES	Source	Metathesaurus FDA Structured Product Labels
SOURCES	Source	Multum MediSource Lexicon
SOURCES	Source	National Drug Data File Plus Source Vocabulary
SOURCES	Source	Veterans Health Administration National Drug File