FDA.reportPublic FDA data

acetaminophen 325 MG / phenylephrine hydrochloride 5 MG / pyrilamine maleate 25 MG Oral Tablet

RxCUI
1241829
RxNorm name
acetaminophen 325 MG / phenylephrine hydrochloride 5 MG / pyrilamine maleate 25 MG Oral Tablet
Display name
Acetaminophen/Phenylephrine/Pyrilamine (Oral Pill)
Full name
acetaminophen 325 MG / phenylephrine hydrochloride 5 MG / pyrilamine maleate 25 MG Oral Tablet
Term type
SCD
Status
Active
Strength
325-5-25 mg
Dose form
Tab
Route
Oral Pill
Updated
2026-07-18 07:01:56

RxNorm Status History#

Status
Active
Source
RXNORM
Current
YES
Release start
022012
Active start
022012
Multiple ingredient
YES
Branded
NO

Ingredients And Strength#

Ingredient, Strength, Base table
IngredientStrengthBaseBasis of strength
acetaminophen325 MG / 1 EACHacetaminophenacetaminophen
phenylephrine hydrochloride5 MG / 1 EACHphenylephrinephenylephrine hydrochloride
pyrilamine maleate25 MG / 1 EACHpyrilaminepyrilamine maleate

Dose Form Concepts#

Dose form, RxCUI table
Dose formRxCUI
Oral Tablet317541

Derived Ingredient Concepts#

Ingredient, RxCUI table
IngredientRxCUI
acetaminophen161
phenylephrine8163
pyrilamine9009

Source Vocabulary Codes#

Code type, Value, Category table
Code typeValueCategory
PRESCRIBABLEYATTRIBUTES
RXNAV_STRacetaminophen 325 MG / phenylephrine hydrochloride 5 MG / pyrilamine maleate 25 MG Oral TabletNAMES
RxNorm Nameacetaminophen 325 MG / phenylephrine hydrochloride 5 MG / pyrilamine maleate 25 MG Oral TabletNAMES
RxNorm SynonymAPAP 325 MG / Phenylephrine Hydrochloride 5 MG / Pyrilamine Maleate 25 MG Oral TabletNAMES
TTYSCDATTRIBUTES
RxCUI1241829CODES

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 1 matching rows.

NDC11, Source, Active table
NDC11SourceActive
15370003410rxnav_ndcsyes

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

Drug Classes#

Source, Class ID, Class table
SourceClass IDClassTypeRelationshipDrug concept
ATCC01CAAdrenergic and dopaminergic agentsATC1-4phenylephrine
ATCN02BEAnilidesATC1-4acetaminophen
ATCD04AAAntihistamines for topical useATC1-4pyrilamine
ATCC05AXOther agents for treatment of hemorrhoids and anal fissures for topical useATC1-4phenylephrine
ATCR06ACSubstituted ethylene diaminesATC1-4pyrilamine
ATCR01BASympathomimeticsATC1-4phenylephrine
ATCS01FBSympathomimetics excl. antiglaucoma preparationsATC1-4phenylephrine
ATCS01GASympathomimetics used as decongestantsATC1-4phenylephrine
ATCR01ABSympathomimetics, combinations excl. corticosteroidsATC1-4phenylephrine
ATCR01AASympathomimetics, plainATC1-4phenylephrine
FDASPLN0000186105alpha-1 Adrenergic AgonistEPChas_epcphenylephrine
MEDRTD000082AcetaminophenCHEMhas_ingredientacetaminophen
MEDRTD010656PhenylephrineCHEMhas_ingredientphenylephrine hydrochloride
MEDRTD010656PhenylephrineCHEMhas_ingredientphenylephrine
MEDRTD011738PyrilamineCHEMhas_ingredientpyrilamine maleate
MEDRTD011738PyrilamineCHEMhas_ingredientpyrilamine
MEDRTD013447SulfitesCHEMci_chemclassphenylephrine hydrochloride
MEDRTD013447SulfitesCHEMci_chemclassphenylephrine
MEDRTD003233Conjunctivitis, AllergicDISEASEmay_treatpyrilamine maleate
MEDRTD003233Conjunctivitis, AllergicDISEASEmay_treatpyrilamine
MEDRTD004342Drug HypersensitivityDISEASEci_withphenylephrine hydrochloride
MEDRTD004342Drug HypersensitivityDISEASEci_withpyrilamine maleate
MEDRTD004342Drug HypersensitivityDISEASEci_withpyrilamine
MEDRTD004342Drug HypersensitivityDISEASEci_withacetaminophen
MEDRTD004342Drug HypersensitivityDISEASEci_withphenylephrine
MEDRTD005334FeverDISEASEmay_preventacetaminophen
MEDRTD005334FeverDISEASEmay_treatacetaminophen
MEDRTD005401Fissure in AnoDISEASEmay_treatphenylephrine hydrochloride
MEDRTD005401Fissure in AnoDISEASEmay_treatphenylephrine
MEDRTD005902Glaucoma, Open-AngleDISEASEmay_treatphenylephrine hydrochloride
MEDRTD005902Glaucoma, Open-AngleDISEASEmay_treatphenylephrine
MEDRTD005955Glucosephosphate Dehydrogenase DeficiencyDISEASEci_withacetaminophen
MEDRTD006484HemorrhoidsDISEASEmay_treatphenylephrine hydrochloride
MEDRTD006484HemorrhoidsDISEASEmay_treatphenylephrine
MEDRTD006973HypertensionDISEASEci_withphenylephrine hydrochloride
MEDRTD006973HypertensionDISEASEci_withphenylephrine
MEDRTD007022HypotensionDISEASEmay_treatphenylephrine hydrochloride
MEDRTD007022HypotensionDISEASEmay_treatphenylephrine
MEDRTD008107Liver DiseasesDISEASEci_withacetaminophen
MEDRTD015878MydriasisDISEASEinducesphenylephrine hydrochloride
MEDRTD015878MydriasisDISEASEinducesphenylephrine
MEDRTD010146PainDISEASEmay_preventacetaminophen
MEDRTD010146PainDISEASEmay_treatacetaminophen
MEDRTD011537PruritusDISEASEmay_treatpyrilamine maleate
MEDRTD011537PruritusDISEASEmay_treatpyrilamine
MEDRTD011538Pruritus AniDISEASEmay_treatphenylephrine hydrochloride
MEDRTD011538Pruritus AniDISEASEmay_treatphenylephrine
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatpyrilamine
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatpyrilamine maleate
MEDRTD006255Rhinitis, Allergic, SeasonalDISEASEmay_treatpyrilamine
MEDRTD006255Rhinitis, Allergic, SeasonalDISEASEmay_treatpyrilamine maleate
MEDRTD012223Rhinitis, VasomotorDISEASEmay_treatphenylephrine
MEDRTD012223Rhinitis, VasomotorDISEASEmay_treatphenylephrine hydrochloride
MEDRTD012772Shock, SepticDISEASEmay_treatphenylephrine hydrochloride
MEDRTD012772Shock, SepticDISEASEmay_treatphenylephrine
MEDRTD013617Tachycardia, SupraventricularDISEASEmay_treatphenylephrine hydrochloride
MEDRTD013617Tachycardia, SupraventricularDISEASEmay_treatphenylephrine
MEDRTD017180Tachycardia, VentricularDISEASEci_withphenylephrine
MEDRTD017180Tachycardia, VentricularDISEASEci_withphenylephrine hydrochloride
MEDRTN0000000209Adrenergic alpha-AgonistsMOAhas_moaphenylephrine hydrochloride
MEDRTN0000000209Adrenergic alpha-AgonistsMOAhas_moaphenylephrine
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moapyrilamine maleate
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moapyrilamine
MEDRTN0000000108Prostaglandin Receptor AntagonistsMOAhas_moaacetaminophen
MEDRTN0000175724Central Nervous System Activity AlterationPEhas_peacetaminophen
MEDRTN0000008371Conjunctival Arterial VasoconstrictionPEhas_pephenylephrine hydrochloride
MEDRTN0000008371Conjunctival Arterial VasoconstrictionPEhas_pephenylephrine
MEDRTN0000008657Decreased Histamine ActivityPEhas_pepyrilamine maleate
MEDRTN0000008657Decreased Histamine ActivityPEhas_pepyrilamine
MEDRTN0000008896Decreased Nasal and Sinus SecretionsPEhas_pephenylephrine hydrochloride
MEDRTN0000008896Decreased Nasal and Sinus SecretionsPEhas_pephenylephrine
MEDRTN0000008836Decreased Prostaglandin ProductionPEhas_peacetaminophen
MEDRTN0000009072Hypothalamic Endocrine Activity AlterationPEhas_peacetaminophen
MEDRTN0000175725Peripheral Nervous System Activity AlterationPEhas_peacetaminophen
MEDRTN0000000026Hepatic MetabolismPKhas_pkacetaminophen
MEDRTN0000000042Renal ExcretionPKhas_pkacetaminophen

Properties#

Category, Property, Value table
CategoryPropertyValue
ATTRIBUTESAVAILABLE_STRENGTH325 MG / 5 MG / 25 MG
ATTRIBUTESGENERAL_CARDINALITYMULTI
ATTRIBUTESHUMAN_DRUGUS
ATTRIBUTESPRESCRIBABLEY
ATTRIBUTESRXNAV_HUMAN_DRUGUS
ATTRIBUTESTTYSCD
CODESRxCUI1241829
NAMESPrescribable Synonymacetaminophen 325 MG / phenylephrine HCl 5 MG / pyrilamine maleate 25 MG Oral Tablet
NAMESRXNAV_STRacetaminophen 325 MG / phenylephrine hydrochloride 5 MG / pyrilamine maleate 25 MG Oral Tablet
NAMESRxNorm Nameacetaminophen 325 MG / phenylephrine hydrochloride 5 MG / pyrilamine maleate 25 MG Oral Tablet
NAMESRxNorm SynonymAPAP 325 MG / Phenylephrine Hydrochloride 5 MG / Pyrilamine Maleate 25 MG Oral Tablet
SOURCESSourceMicromedex RED BOOK