acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 1 MG/ML / doxylamine succinate 0.25 MG/ML Oral Solution

RxCUI: 1244918
RxNorm name: acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 1 MG/ML / doxylamine succinate 0.25 MG/ML Oral Solution
Term type: SCD
Status: Active
Updated: 2026-07-18 07:02:40

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 032012
Active start: 032012
Multiple ingredient: YES
Branded: NO

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
acetaminophen	21.7 MG / 1 ML	acetaminophen	acetaminophen
dextromethorphan hydrobromide	1 MG / 1 ML	dextromethorphan	dextromethorphan hydrobromide
doxylamine succinate	0.25 MG / 1 ML	doxylamine	doxylamine succinate

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Oral Solution	316968

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
acetaminophen	161
dextromethorphan	3289
doxylamine	3642

Source Vocabulary Codes#

Code type, Value, Category table
Code type	Value	Category
RXNAV_STR	acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 1 MG/ML / doxylamine succinate 0.25 MG/ML Oral Solution	NAMES
RxNorm Name	acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 1 MG/ML / doxylamine succinate 0.25 MG/ML Oral Solution	NAMES
RxNorm Synonym	acetaminophen 650 MG / dextromethorphan HBr 30 MG / doxylamine succinate 7.5 MG per 30 ML Oral Solution	NAMES
RxNorm Synonym	APAP 21.7 MG/ML / dextromethorphan hydrobromide 1 MG/ML / doxylamine succinate 0.25 MG/ML Oral Solution	NAMES
TTY	SCD	ATTRIBUTES
RxCUI	1244918	CODES
MMSL_CODE	BD28656	CODES
MMSL_CODE	CD28656	CODES

RxNav Current And Historical NDCs#

NDC11, Source, Active table
NDC11	Source	Active
23900001412	rxnav_historical_indirect
37000049708	rxnav_historical_indirect
63868080708	rxnav_historical
63868080712	rxnav_historical

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	R06AA	Aminoalkyl ethers	ATC1-4		doxylamine
ATC	N02BE	Anilides	ATC1-4		acetaminophen
ATC	R05DA	Opium alkaloids and derivatives	ATC1-4		dextromethorphan
FDASPL	N0000175750	Antihistamine	EPC	has_epc	doxylamine
FDASPL	N0000182149	Sigma-1 Agonist	EPC	has_epc	dextromethorphan
FDASPL	N0000181821	Uncompetitive N-methyl-D-aspartate Receptor Antagonist	EPC	has_epc	dextromethorphan
FDASPL	N0000000207	Histamine Receptor Antagonists	MOA	has_moa	doxylamine
FDASPL	N0000182147	Sigma-1 Receptor Agonists	MOA	has_moa	dextromethorphan
FDASPL	N0000181819	Uncompetitive NMDA Receptor Antagonists	MOA	has_moa	dextromethorphan
MEDRT	D000082	Acetaminophen	CHEM	has_ingredient	acetaminophen
MEDRT	D003915	Dextromethorphan	CHEM	has_ingredient	dextromethorphan hydrobromide
MEDRT	D003915	Dextromethorphan	CHEM	has_ingredient	dextromethorphan
MEDRT	D004319	Doxylamine	CHEM	has_ingredient	doxylamine
MEDRT	D004319	Doxylamine	CHEM	has_ingredient	doxylamine succinate
MEDRT	D003371	Cough	DISEASE	may_treat	dextromethorphan
MEDRT	D003371	Cough	DISEASE	may_prevent	dextromethorphan
MEDRT	D003371	Cough	DISEASE	may_treat	dextromethorphan hydrobromide
MEDRT	D003371	Cough	DISEASE	may_prevent	dextromethorphan hydrobromide
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	acetaminophen
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	doxylamine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	dextromethorphan
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	doxylamine succinate
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	dextromethorphan hydrobromide
MEDRT	D005334	Fever	DISEASE	may_prevent	acetaminophen
MEDRT	D005334	Fever	DISEASE	may_treat	acetaminophen
MEDRT	D005955	Glucosephosphate Dehydrogenase Deficiency	DISEASE	ci_with	acetaminophen
MEDRT	D006261	Headache	DISEASE	may_treat	doxylamine
MEDRT	D006261	Headache	DISEASE	may_treat	doxylamine succinate
MEDRT	D008107	Liver Diseases	DISEASE	ci_with	acetaminophen
MEDRT	D010146	Pain	DISEASE	may_treat	acetaminophen
MEDRT	D010146	Pain	DISEASE	may_prevent	acetaminophen
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	doxylamine
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	doxylamine succinate
MEDRT	D007319	Sleep Initiation and Maintenance Disorders	DISEASE	may_treat	doxylamine
MEDRT	D007319	Sleep Initiation and Maintenance Disorders	DISEASE	may_treat	doxylamine succinate
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	doxylamine succinate
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	doxylamine
MEDRT	N0000000184	Monoamine Oxidase Inhibitors	MOA	ci_moa	dextromethorphan
MEDRT	N0000000184	Monoamine Oxidase Inhibitors	MOA	ci_moa	dextromethorphan hydrobromide
MEDRT	N0000000108	Prostaglandin Receptor Antagonists	MOA	has_moa	acetaminophen
MEDRT	N0000000109	Serotonin Uptake Inhibitors	MOA	has_moa	dextromethorphan hydrobromide
MEDRT	N0000000109	Serotonin Uptake Inhibitors	MOA	has_moa	dextromethorphan
MEDRT	N0000182147	Sigma-1 Receptor Agonists	MOA	has_moa	dextromethorphan hydrobromide
MEDRT	N0000182147	Sigma-1 Receptor Agonists	MOA	has_moa	dextromethorphan
MEDRT	N0000181819	Uncompetitive NMDA Receptor Antagonists	MOA	has_moa	dextromethorphan hydrobromide
MEDRT	N0000181819	Uncompetitive NMDA Receptor Antagonists	MOA	has_moa	dextromethorphan
MEDRT	N0000175724	Central Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000008657	Decreased Histamine Activity	PE	has_pe	doxylamine succinate
MEDRT	N0000008657	Decreased Histamine Activity	PE	has_pe	doxylamine
MEDRT	N0000008701	Decreased Medullary Respiratory Drive	PE	has_pe	dextromethorphan hydrobromide
MEDRT	N0000008701	Decreased Medullary Respiratory Drive	PE	has_pe	dextromethorphan
MEDRT	N0000008836	Decreased Prostaglandin Production	PE	has_pe	acetaminophen
MEDRT	N0000009072	Hypothalamic Endocrine Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000175725	Peripheral Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000000026	Hepatic Metabolism	PK	has_pk	acetaminophen
MEDRT	N0000000042	Renal Excretion	PK	has_pk	acetaminophen

Group, Type, Concept table
Group	Type	Concept	Source
DF	DF	Oral Solution	rxnav_allrelated
DFG	DFG	Oral Liquid Product	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
IN	IN	acetaminophen	rxnav_allrelated
IN	IN	dextromethorphan	rxnav_allrelated
IN	IN	doxylamine	rxnav_allrelated
MIN	MIN	acetaminophen / dextromethorphan / doxylamine	rxnav_allrelated
PIN	PIN	dextromethorphan hydrobromide	rxnav_allrelated
PIN	PIN	doxylamine succinate	rxnav_allrelated
SCD	SCD	acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 1 MG/ML / doxylamine succinate 0.25 MG/ML Oral Solution	rxnav_allrelated
SCDC	SCDC	acetaminophen 21.7 MG/ML	rxnav_allrelated
SCDC	SCDC	dextromethorphan hydrobromide 1 MG/ML	rxnav_allrelated
SCDC	SCDC	doxylamine succinate 0.25 MG/ML	rxnav_allrelated
SCDF	SCDF	acetaminophen / dextromethorphan / doxylamine Oral Solution	rxnav_allrelated
SCDFP	SCDFP	acetaminophen / dextromethorphan hydrobromide / doxylamine succinate Oral Solution	rxnav_allrelated
SCDG	SCDG	acetaminophen / dextromethorphan / doxylamine Oral Liquid Product	rxnav_allrelated
SCDG	SCDG	acetaminophen / dextromethorphan / doxylamine Oral Product	rxnav_allrelated
SCDGP	SCDGP	acetaminophen / dextromethorphan hydrobromide / doxylamine succinate Oral Liquid Product	rxnav_allrelated
SCDGP	SCDGP	acetaminophen / dextromethorphan hydrobromide / doxylamine succinate Oral Product	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	21.7 MG/ML / 1 MG/ML / 0.25 MG/ML (expressed as doxylamine succinate)
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
ATTRIBUTES	TTY	SCD
CODES	MMSL_CODE	BD28656
CODES	MMSL_CODE	CD28656
CODES	RxCUI	1244918
NAMES	RXNAV_STR	acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 1 MG/ML / doxylamine succinate 0.25 MG/ML Oral Solution
NAMES	RxNorm Name	acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 1 MG/ML / doxylamine succinate 0.25 MG/ML Oral Solution
NAMES	RxNorm Synonym	acetaminophen 650 MG / dextromethorphan HBr 30 MG / doxylamine succinate 7.5 MG per 30 ML Oral Solution
NAMES	RxNorm Synonym	APAP 21.7 MG/ML / dextromethorphan hydrobromide 1 MG/ML / doxylamine succinate 0.25 MG/ML Oral Solution
SOURCES	Source	Micromedex RED BOOK

acetaminophen 21.7 MG/ML / dextromethorphan hydrobromide 1 MG/ML / doxylamine succinate 0.25 MG/ML Oral Solution

RxNorm Status History#

Ingredients And Strength#

Dose Form Concepts#

Derived Ingredient Concepts#

Source Vocabulary Codes#

RxNav Current And Historical NDCs#

Drug Classes#

Related Concepts#

Properties#