Home RxNorm 1291711 acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG / pseudoephedrine hydrochloride 30 MG Oral Tablet Drug identity information. FDA.report links public drug records from RxNav, DailyMed, FDA NDC, Drugs@FDA, and related public sources where available. This page is informational only and is not medical, prescribing, or regulatory advice.
RxCUI 1291711
RxNorm name acetaminophen 500 MG / diphenhydramine hydrochloride 25 MG / pseudoephedrine hydrochloride 30 MG Oral Tablet
Term type SCD
Status Active
Updated 2026-07-25 06:55:24 RxNorm Status History#
Status Active
Source RXNORM
Current YES
Release start 062012
Active start 062012
Multiple ingredient YES
Branded NO Ingredients And Strength# Derived Ingredient Concepts# RxNav Current And Historical NDCs# RxNav current and historical NDC rows page 1 of 1 · 15 matching rows.
NDC11, Source, Active table NDC11 Source Active 00045017410 rxnav_historical_indirect 00045017412 rxnav_historical_indirect 00045017420 rxnav_historical_indirect 00045017424 rxnav_historical_indirect 00045044324 rxnav_historical_indirect 00045083624 rxnav_historical_indirect 00501200624 rxnav_historical_indirect 00501203020 rxnav_historical_indirect 00501275220 rxnav_historical_indirect 12547017034 rxnav_historical_indirect 12547017050 rxnav_historical_indirect 50580017424 rxnav_historical 50580037925 rxnav_historical_indirect 50580044322 rxnav_historical_indirect 50580044324 rxnav_historical_indirect
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Matched openFDA labels page 1 of 1 · 1 matching rows.
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Drug Classes# Source, Class ID, Class table Source Class ID Class Type Relationship Drug concept ATC R06AA Aminoalkyl ethers ATC1-4 diphenhydramine ATC N02BE Anilides ATC1-4 acetaminophen ATC D04AA Antihistamines for topical use ATC1-4 diphenhydramine ATC R01BA Sympathomimetics ATC1-4 pseudoephedrine FDASPL N0000175552 alpha-Adrenergic Agonist EPC has_epc pseudoephedrine FDASPL N0000175587 Histamine-1 Receptor Antagonist EPC has_epc diphenhydramine FDASPL N0000000190 Histamine H1 Receptor Antagonists MOA has_moa diphenhydramine MEDRT D000082 Acetaminophen CHEM has_ingredient acetaminophen MEDRT D004155 Diphenhydramine CHEM has_ingredient diphenhydramine hydrochloride MEDRT D004155 Diphenhydramine CHEM has_ingredient diphenhydramine MEDRT D054199 Pseudoephedrine CHEM has_ingredient pseudoephedrine hydrochloride MEDRT D054199 Pseudoephedrine CHEM has_ingredient pseudoephedrine MEDRT D001008 Anxiety Disorders DISEASE may_treat diphenhydramine MEDRT D001008 Anxiety Disorders DISEASE may_treat diphenhydramine hydrochloride MEDRT D001249 Asthma DISEASE may_treat pseudoephedrine MEDRT D001249 Asthma DISEASE may_treat pseudoephedrine hydrochloride MEDRT D003139 Common Cold DISEASE may_treat pseudoephedrine MEDRT D003139 Common Cold DISEASE may_treat pseudoephedrine hydrochloride MEDRT D004342 Drug Hypersensitivity DISEASE ci_with acetaminophen MEDRT D004342 Drug Hypersensitivity DISEASE ci_with diphenhydramine hydrochloride MEDRT D004342 Drug Hypersensitivity DISEASE ci_with diphenhydramine MEDRT D004342 Drug Hypersensitivity DISEASE ci_with pseudoephedrine hydrochloride MEDRT D004342 Drug Hypersensitivity DISEASE ci_with pseudoephedrine MEDRT D005334 Fever DISEASE may_treat acetaminophen MEDRT D005334 Fever DISEASE may_prevent acetaminophen MEDRT D005955 Glucosephosphate Dehydrogenase Deficiency DISEASE ci_with acetaminophen MEDRT D007231 Infant, Newborn DISEASE ci_with diphenhydramine MEDRT D007231 Infant, Newborn DISEASE ci_with diphenhydramine hydrochloride MEDRT D007234 Infant, Premature DISEASE ci_with diphenhydramine hydrochloride MEDRT D007234 Infant, Premature DISEASE ci_with diphenhydramine MEDRT D007774 Lactation DISEASE ci_with diphenhydramine MEDRT D007774 Lactation DISEASE ci_with diphenhydramine hydrochloride MEDRT D008107 Liver Diseases DISEASE ci_with acetaminophen MEDRT D009041 Motion Sickness DISEASE may_treat diphenhydramine hydrochloride MEDRT D009041 Motion Sickness DISEASE may_treat diphenhydramine MEDRT D009325 Nausea DISEASE may_treat diphenhydramine hydrochloride MEDRT D009325 Nausea DISEASE may_treat diphenhydramine MEDRT D010146 Pain DISEASE may_prevent acetaminophen MEDRT D010146 Pain DISEASE may_treat acetaminophen MEDRT D012221 Rhinitis, Allergic, Perennial DISEASE may_treat pseudoephedrine hydrochloride MEDRT D012221 Rhinitis, Allergic, Perennial DISEASE may_treat diphenhydramine hydrochloride MEDRT D012221 Rhinitis, Allergic, Perennial DISEASE may_treat pseudoephedrine MEDRT D012221 Rhinitis, Allergic, Perennial DISEASE may_treat diphenhydramine MEDRT D012852 Sinusitis DISEASE may_treat pseudoephedrine hydrochloride MEDRT D012852 Sinusitis DISEASE may_treat pseudoephedrine MEDRT D007319 Sleep Initiation and Maintenance Disorders DISEASE may_treat diphenhydramine hydrochloride MEDRT D007319 Sleep Initiation and Maintenance Disorders DISEASE may_treat diphenhydramine MEDRT D012912 Sneezing DISEASE may_treat diphenhydramine hydrochloride MEDRT D012912 Sneezing DISEASE may_treat diphenhydramine MEDRT D013224 Status Asthmaticus DISEASE ci_with diphenhydramine MEDRT D013224 Status Asthmaticus DISEASE ci_with diphenhydramine hydrochloride MEDRT D014581 Urticaria DISEASE may_treat diphenhydramine MEDRT D014581 Urticaria DISEASE may_treat diphenhydramine hydrochloride MEDRT N0000000209 Adrenergic alpha-Agonists MOA has_moa pseudoephedrine hydrochloride MEDRT N0000000209 Adrenergic alpha-Agonists MOA has_moa pseudoephedrine MEDRT N0000000245 Adrenergic beta-Agonists MOA has_moa pseudoephedrine hydrochloride MEDRT N0000000245 Adrenergic beta-Agonists MOA has_moa pseudoephedrine MEDRT N0000000190 Histamine H1 Receptor Antagonists MOA has_moa diphenhydramine hydrochloride MEDRT N0000000190 Histamine H1 Receptor Antagonists MOA has_moa diphenhydramine MEDRT N0000000184 Monoamine Oxidase Inhibitors MOA ci_moa pseudoephedrine hydrochloride MEDRT N0000000184 Monoamine Oxidase Inhibitors MOA ci_moa pseudoephedrine MEDRT N0000000108 Prostaglandin Receptor Antagonists MOA has_moa acetaminophen MEDRT N0000008322 Bronchodilation PE has_pe pseudoephedrine MEDRT N0000008322 Bronchodilation PE has_pe pseudoephedrine hydrochloride MEDRT N0000175724 Central Nervous System Activity Alteration PE has_pe acetaminophen MEDRT N0000008836 Decreased Prostaglandin Production PE has_pe acetaminophen MEDRT N0000009072 Hypothalamic Endocrine Activity Alteration PE has_pe acetaminophen MEDRT N0000175725 Peripheral Nervous System Activity Alteration PE has_pe acetaminophen MEDRT N0000009908 Vasoconstriction PE has_pe pseudoephedrine MEDRT N0000009908 Vasoconstriction PE has_pe pseudoephedrine hydrochloride MEDRT N0000000026 Hepatic Metabolism PK has_pk acetaminophen MEDRT N0000000042 Renal Excretion PK has_pk acetaminophen
Properties# Category, Property, Value table Category Property Value ATTRIBUTES ACTIVATED 05/31/2023 ATTRIBUTES ACTIVATED 06/30/2026 ATTRIBUTES AVAILABLE_STRENGTH 500 MG / 25 MG / 30 MG ATTRIBUTES GENERAL_CARDINALITY MULTI ATTRIBUTES HUMAN_DRUG US ATTRIBUTES RXNAV_HUMAN_DRUG US NAMES Prescribable Synonym acetaminophen 500 MG / diphenhydrAMINE HCl 25 MG / pseudoephedrine HCl 30 MG Oral Tablet NAMES Tallman Synonym acetaminophen 500 MG / diphenhydrAMINE hydrochloride 25 MG / pseudoephedrine hydrochloride 30 MG Oral Tablet NAMES Tallman Synonym APAP 500 MG / diphenhydrAMINE Hydrochloride 25 MG / Pseudoephedrine Hydrochloride 30 MG Oral Tablet SOURCES Source Metathesaurus FDA Structured Product Labels