FDA.reportPublic FDA data

diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Solution

RxCUI
1294589
RxNorm name
diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Solution
Display name
diphenhydrAMINE/Zinc acetate (Topical)
Full name
diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Solution
Term type
SCD
Status
Active
Strength
2-0.1%
Dose form
Sol
Route
Topical
Updated
2026-07-20 06:53:40

RxNorm Status History#

Status
Active
Source
RXNORM
Current
YES
Release start
062012
Active start
062012
Multiple ingredient
YES
Branded
NO

Ingredients And Strength#

Ingredient, Strength, Base table
IngredientStrengthBaseBasis of strength
diphenhydramine hydrochloride20 MG / 1 MLdiphenhydraminediphenhydramine hydrochloride
zinc acetate1 MG / 1 MLzinc acetatezinc acetate

Dose Form Concepts#

Dose form, RxCUI table
Dose formRxCUI
Topical Solution316986

Derived Ingredient Concepts#

Ingredient, RxCUI table
IngredientRxCUI
diphenhydramine3498
zinc acetate58295

Source Vocabulary Codes#

Code type, Value, Category table
Code typeValueCategory
PRESCRIBABLEYATTRIBUTES
RXNAV_STRdiphenhydrAMINE hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical SolutionNAMES
RxNorm Namediphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical SolutionNAMES
RxNorm Synonymdiphenhydramine hydrochloride 2 % / zinc acetate 0.1 % Topical SolutionNAMES
TTYSCDATTRIBUTES
SPL_SET_ID236415fc-f923-4a82-b54a-ecaf666dd2e0CODES
RxCUI1294589CODES
MMSL_CODECD11360CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDCProduct NDCNameLabelerApplication
59555-002-1859555-002Industrial Itch and Pain Relief DIPHENHYDRAMINE HYDROCHLORIDE and Zinc AcetateR & R Lotion, IncM017
59555-002-1959555-002Industrial Itch and Pain Relief DIPHENHYDRAMINE HYDROCHLORIDE and Zinc AcetateR & R Lotion, IncM017

Drugs@FDA Applications#

Application, NDC, Name table
ApplicationNDCNameMarketing categoryLabeler
M01759555-002Industrial Itch and Pain Relief DIPHENHYDRAMINE HYDROCHLORIDE and Zinc AcetateOTC MONOGRAPH DRUGR & R Lotion, Inc

RxNav Current And Historical NDCs#

NDC11, Source, Active table
NDC11SourceActive
59555000218rxnav_ndcsyes
59555000219rxnav_ndcsyes
11822039230rxnav_historical
11822372310rxnav_historical
11822928120rxnav_historical
49348092530rxnav_historical_indirect
50428237741rxnav_historical
50428460403rxnav_historical
59555001018rxnav_historical
59555001019rxnav_historical
59555023004rxnav_historical
59555023007rxnav_historical
59555023018rxnav_historical
59555023019rxnav_historical

DailyMed RxNorm Mappings#

Set ID, RxNorm string, TTY table
Set IDRxNorm stringTTYSPL versionLabelEffective
309d9be0-e367-429a-a1fa-ab7855477c8adiphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical SolutionSCD8Benadryl ® EXTRA STRENGTH ITCH RELIEF STICK20250710
309d9be0-e367-429a-a1fa-ab7855477c8adiphenhydrAMINE HCl 2 % / zinc acetate 0.1 % Topical SolutionPSN8Benadryl ® EXTRA STRENGTH ITCH RELIEF STICK20250710
309d9be0-e367-429a-a1fa-ab7855477c8adiphenhydramine hydrochloride 2 % / zinc acetate 0.1 % Topical SolutionSY8Benadryl ® EXTRA STRENGTH ITCH RELIEF STICK20250710
236415fc-f923-4a82-b54a-ecaf666dd2e0diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical SolutionSCD3Industrial Itch and Pain Relief20250911
236415fc-f923-4a82-b54a-ecaf666dd2e0diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % Topical SolutionSY3Industrial Itch and Pain Relief20250911
236415fc-f923-4a82-b54a-ecaf666dd2e0diphenhydrAMINE HCl 2 % / zinc acetate 0.1 % Topical SolutionPSN3Industrial Itch and Pain Relief20250911
9cc4543c-12f9-46c8-864b-bc1f5705569adiphenhydrAMINE HCl 2 % / zinc acetate 0.1 % Topical SolutionPSN2Rugid Itch and Pain Relief20210114
9cc4543c-12f9-46c8-864b-bc1f5705569adiphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical SolutionSCD2Rugid Itch and Pain Relief20210114
9cc4543c-12f9-46c8-864b-bc1f5705569adiphenhydramine hydrochloride 2 % / zinc acetate 0.1 % Topical SolutionSY2Rugid Itch and Pain Relief20210114
7661cbc8-6b2e-4144-9085-3a58040446f2diphenhydrAMINE HCl 2 % / zinc acetate 0.1 % Topical SolutionPSN1IC ® Ivy Relief20210924
7661cbc8-6b2e-4144-9085-3a58040446f2diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % Topical SolutionSY1IC ® Ivy Relief20210924
7661cbc8-6b2e-4144-9085-3a58040446f2diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical SolutionSCD1IC ® Ivy Relief20210924

DailyMed Labels#

Set ID, Title, Manufacturer table
Set IDTitleManufacturerEffective
236415fc-f923-4a82-b54a-ecaf666dd2e0Industrial Itch and Pain ReliefR & R Lotion, Inc20250911
7661cbc8-6b2e-4144-9085-3a58040446f2IC ® Ivy ReliefR & R Lotion, Inc20210924
9cc4543c-12f9-46c8-864b-bc1f5705569aRugid Itch and Pain ReliefR & R Lotion, Inc20210114

Drug Classes#

Source, Class ID, Class table
SourceClass IDClassTypeRelationshipDrug concept
ATCR06AAAminoalkyl ethersATC1-4diphenhydramine
ATCD04AAAntihistamines for topical useATC1-4diphenhydramine
ATCA16AXVarious alimentary tract and metabolism productsATC1-4zinc acetate
FDASPLN0000175587Histamine-1 Receptor AntagonistEPChas_epcdiphenhydramine
FDASPLN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine
MEDRTD004155DiphenhydramineCHEMhas_ingredientdiphenhydramine hydrochloride
MEDRTD004155DiphenhydramineCHEMhas_ingredientdiphenhydramine
MEDRTD019345Zinc AcetateCHEMhas_ingredientzinc acetate
MEDRTD001008Anxiety DisordersDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD001008Anxiety DisordersDISEASEmay_treatdiphenhydramine
MEDRTD003139Common ColdDISEASEmay_treatzinc acetate
MEDRTD004342Drug HypersensitivityDISEASEci_withdiphenhydramine hydrochloride
MEDRTD004342Drug HypersensitivityDISEASEci_withdiphenhydramine
MEDRTD007231Infant, NewbornDISEASEci_withdiphenhydramine hydrochloride
MEDRTD007231Infant, NewbornDISEASEci_withdiphenhydramine
MEDRTD007234Infant, PrematureDISEASEci_withdiphenhydramine hydrochloride
MEDRTD007234Infant, PrematureDISEASEci_withdiphenhydramine
MEDRTD007774LactationDISEASEci_withdiphenhydramine
MEDRTD007774LactationDISEASEci_withdiphenhydramine hydrochloride
MEDRTD009041Motion SicknessDISEASEmay_treatdiphenhydramine
MEDRTD009041Motion SicknessDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD009325NauseaDISEASEmay_treatdiphenhydramine
MEDRTD009325NauseaDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatdiphenhydramine
MEDRTD012221Rhinitis, Allergic, PerennialDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD012883Skin UlcerDISEASEmay_treatzinc acetate
MEDRTD007319Sleep Initiation and Maintenance DisordersDISEASEmay_treatdiphenhydramine
MEDRTD007319Sleep Initiation and Maintenance DisordersDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD012912SneezingDISEASEmay_treatdiphenhydramine
MEDRTD012912SneezingDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD013224Status AsthmaticusDISEASEci_withdiphenhydramine hydrochloride
MEDRTD013224Status AsthmaticusDISEASEci_withdiphenhydramine
MEDRTD014581UrticariaDISEASEmay_treatdiphenhydramine
MEDRTD014581UrticariaDISEASEmay_treatdiphenhydramine hydrochloride
MEDRTD014947Wounds and InjuriesDISEASEmay_treatzinc acetate
MEDRTN0000000226Acid-Base ActivityMOAhas_moazinc acetate
MEDRTN0000000220Electrolyte ActivityMOAhas_moazinc acetate
MEDRTN0000000163Enzyme InteractionsMOAhas_moazinc acetate
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine
MEDRTN0000000190Histamine H1 Receptor AntagonistsMOAhas_moadiphenhydramine hydrochloride

Properties#

Category, Property, Value table
CategoryPropertyValue
ATTRIBUTESAVAILABLE_STRENGTH20 MG/ML / 1 MG/ML
ATTRIBUTESGENERAL_CARDINALITYMULTI
ATTRIBUTESHUMAN_DRUGUS
ATTRIBUTESPRESCRIBABLEY
ATTRIBUTESRXNAV_HUMAN_DRUGUS
ATTRIBUTESSCHEDULE0
ATTRIBUTESTTYSCD
CODESMMSL_CODECD11360
CODESRxCUI1294589
CODESSPL_SET_ID236415fc-f923-4a82-b54a-ecaf666dd2e0
NAMESPrescribable SynonymdiphenhydrAMINE HCl 2 % / zinc acetate 0.1 % Topical Solution
NAMESRXNAV_STRdiphenhydrAMINE hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Solution
NAMESRxNorm Namediphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Solution
NAMESRxNorm Synonymdiphenhydramine hydrochloride 2 % / zinc acetate 0.1 % Topical Solution
NAMESTallman SynonymdiphenhydrAMINE hydrochloride 2 % / zinc acetate 0.1 % Topical Solution
NAMESTallman SynonymdiphenhydrAMINE hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Solution
SOURCESSourceMetathesaurus FDA Structured Product Labels
SOURCESSourceMicromedex RED BOOK
SOURCESSourceMultum MediSource Lexicon
SOURCESSourceNational Drug Data File Plus Source Vocabulary