Home RxNorm 1294592 diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Spray [Benadryl Itch Stopping] Drug identity information. FDA.report links public drug records from RxNav, DailyMed, FDA NDC, Drugs@FDA, and related public sources where available. This page is informational only and is not medical, prescribing, or regulatory advice.
RxCUI 1294592
RxNorm name diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Spray [Benadryl Itch Stopping]
Display name BENADRYL ITCH STOPPING (Topical)
Full name diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Spray [Benadryl Itch Stopping]
Term type SBD
Status Active
Strength 2-0.1%
Dose form Spray
Route Topical
Updated 2026-07-20 06:53:46 RxNorm Status History#
Status Active
Source RXNORM
Current YES
Release start 062012
Active start 062012
Multiple ingredient YES
Branded YES Ingredients And Strength# Derived Ingredient Concepts# FDA NDC Products And Packages# Package NDC, Product NDC, Name table Package NDC Product NDC Name Labeler Application 69968-0270-2 69968-0270 Benadryl Extra Strength Itch Cooling Diphenhydramine Hydrochloride and Zinc Acetate Kenvue Brands LLC M017
Drugs@FDA Applications# Application, NDC, Name table Application NDC Name Marketing category Labeler M017 69968-0270 Benadryl Extra Strength Itch Cooling Diphenhydramine Hydrochloride and Zinc Acetate OTC MONOGRAPH DRUG Kenvue Brands LLC
RxNav Current And Historical NDCs# RxNav current and historical NDC rows page 1 of 1 · 7 matching rows.
NDC11, Source, Active table NDC11 Source Active 00501320302 rxnav_ndcs yes 69968027002 rxnav_ndcs yes 12547017004 rxnav_historical 12547017126 rxnav_historical 58232074502 rxnav_historical 58232075002 rxnav_historical 58232075402 rxnav_historical
UNII Substances# UNII substance links page 1 of 1 · 0 matching rows.
No records found.
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 1 of 1 · 1 matching rows.
DailyMed RxNorm Mappings# Set ID, RxNorm string, TTY table Set ID RxNorm string TTY SPL version Label Effective a7eae5dc-9db6-4bdf-9179-76060e75e044 Benadryl Extra Strength Itch Relief (diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % ) Topical Spray SY 7 Benadryl ® EXTRA STRENGTH ITCH COOLING SPRAY 20250718 a7eae5dc-9db6-4bdf-9179-76060e75e044 Benadryl ReadyMist Itch Stopping (diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % ) Topical Spray SY 7 Benadryl ® EXTRA STRENGTH ITCH COOLING SPRAY 20250718 a7eae5dc-9db6-4bdf-9179-76060e75e044 diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Spray [Benadryl Itch Stopping] SBD 7 Benadryl ® EXTRA STRENGTH ITCH COOLING SPRAY 20250718 a7eae5dc-9db6-4bdf-9179-76060e75e044 Benadryl Itch Cooling (diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % ) Topical Spray SY 7 Benadryl ® EXTRA STRENGTH ITCH COOLING SPRAY 20250718 a7eae5dc-9db6-4bdf-9179-76060e75e044 Benadryl Extra Strength (diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % ) Topical Spray SY 7 Benadryl ® EXTRA STRENGTH ITCH COOLING SPRAY 20250718 a7eae5dc-9db6-4bdf-9179-76060e75e044 Benadryl ITCH COOLING 2 % / 0.1 % Topical Spray PSN 7 Benadryl ® EXTRA STRENGTH ITCH COOLING SPRAY 20250718
Drug Classes# Source, Class ID, Class table Source Class ID Class Type Relationship Drug concept ATC R06AA Aminoalkyl ethers ATC1-4 diphenhydramine ATC D04AA Antihistamines for topical use ATC1-4 diphenhydramine ATC A16AX Various alimentary tract and metabolism products ATC1-4 zinc acetate FDASPL N0000175587 Histamine-1 Receptor Antagonist EPC has_epc diphenhydramine FDASPL N0000000190 Histamine H1 Receptor Antagonists MOA has_moa diphenhydramine MEDRT D004155 Diphenhydramine CHEM has_ingredient diphenhydramine hydrochloride MEDRT D004155 Diphenhydramine CHEM has_ingredient diphenhydramine MEDRT D019345 Zinc Acetate CHEM has_ingredient zinc acetate MEDRT D001008 Anxiety Disorders DISEASE may_treat diphenhydramine hydrochloride MEDRT D001008 Anxiety Disorders DISEASE may_treat diphenhydramine MEDRT D003139 Common Cold DISEASE may_treat zinc acetate MEDRT D004342 Drug Hypersensitivity DISEASE ci_with diphenhydramine hydrochloride MEDRT D004342 Drug Hypersensitivity DISEASE ci_with diphenhydramine MEDRT D007231 Infant, Newborn DISEASE ci_with diphenhydramine hydrochloride MEDRT D007231 Infant, Newborn DISEASE ci_with diphenhydramine MEDRT D007234 Infant, Premature DISEASE ci_with diphenhydramine hydrochloride MEDRT D007234 Infant, Premature DISEASE ci_with diphenhydramine MEDRT D007774 Lactation DISEASE ci_with diphenhydramine MEDRT D007774 Lactation DISEASE ci_with diphenhydramine hydrochloride MEDRT D009041 Motion Sickness DISEASE may_treat diphenhydramine MEDRT D009041 Motion Sickness DISEASE may_treat diphenhydramine hydrochloride MEDRT D009325 Nausea DISEASE may_treat diphenhydramine MEDRT D009325 Nausea DISEASE may_treat diphenhydramine hydrochloride MEDRT D012221 Rhinitis, Allergic, Perennial DISEASE may_treat diphenhydramine MEDRT D012221 Rhinitis, Allergic, Perennial DISEASE may_treat diphenhydramine hydrochloride MEDRT D012883 Skin Ulcer DISEASE may_treat zinc acetate MEDRT D007319 Sleep Initiation and Maintenance Disorders DISEASE may_treat diphenhydramine MEDRT D007319 Sleep Initiation and Maintenance Disorders DISEASE may_treat diphenhydramine hydrochloride MEDRT D012912 Sneezing DISEASE may_treat diphenhydramine MEDRT D012912 Sneezing DISEASE may_treat diphenhydramine hydrochloride MEDRT D013224 Status Asthmaticus DISEASE ci_with diphenhydramine hydrochloride MEDRT D013224 Status Asthmaticus DISEASE ci_with diphenhydramine MEDRT D014581 Urticaria DISEASE may_treat diphenhydramine MEDRT D014581 Urticaria DISEASE may_treat diphenhydramine hydrochloride MEDRT D014947 Wounds and Injuries DISEASE may_treat zinc acetate MEDRT N0000000226 Acid-Base Activity MOA has_moa zinc acetate MEDRT N0000000220 Electrolyte Activity MOA has_moa zinc acetate MEDRT N0000000163 Enzyme Interactions MOA has_moa zinc acetate MEDRT N0000000190 Histamine H1 Receptor Antagonists MOA has_moa diphenhydramine MEDRT N0000000190 Histamine H1 Receptor Antagonists MOA has_moa diphenhydramine hydrochloride
Properties# Category, Property, Value table Category Property Value ATTRIBUTES AVAILABLE_STRENGTH 20 MG/ML / 1 MG/ML ATTRIBUTES GENERAL_CARDINALITY MULTI ATTRIBUTES HUMAN_DRUG US ATTRIBUTES PRESCRIBABLE Y ATTRIBUTES RXNAV_HUMAN_DRUG US ATTRIBUTES SCHEDULE 0 ATTRIBUTES TTY SBD CODES MMSL_CODE BD19730 CODES RxCUI 1294592 CODES SPL_SET_ID a7eae5dc-9db6-4bdf-9179-76060e75e044 NAMES Prescribable Synonym Benadryl ITCH COOLING 2 % / 0.1 % Topical Spray NAMES RXNAV_STR Benadryl Itch Cooling (diphenhydrAMINE hydrochloride 2 % / zinc acetate 0.1 % ) Topical Spray NAMES RxNorm Name diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Spray [Benadryl Itch Stopping] NAMES RxNorm Synonym Benadryl Extra Strength (diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % ) Topical Spray NAMES RxNorm Synonym Benadryl Extra Strength Itch Relief (diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % ) Topical Spray NAMES RxNorm Synonym Benadryl Itch Cooling (diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % ) Topical Spray NAMES RxNorm Synonym Benadryl ReadyMist Itch Stopping (diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % ) Topical Spray NAMES Tallman Synonym Benadryl Extra Strength (diphenhydrAMINE hydrochloride 2 % / zinc acetate 0.1 % ) Topical Spray NAMES Tallman Synonym Benadryl Extra Strength Itch Relief (diphenhydrAMINE hydrochloride 2 % / zinc acetate 0.1 % ) Topical Spray NAMES Tallman Synonym Benadryl Itch Cooling (diphenhydrAMINE hydrochloride 2 % / zinc acetate 0.1 % ) Topical Spray NAMES Tallman Synonym Benadryl ReadyMist Itch Stopping (diphenhydrAMINE hydrochloride 2 % / zinc acetate 0.1 % ) Topical Spray NAMES Tallman Synonym diphenhydrAMINE hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Spray [Benadryl Itch Stopping] SOURCES Source Gold Standard Alchemy SOURCES Source Metathesaurus FDA Structured Product Labels SOURCES Source Micromedex RED BOOK SOURCES Source Multum MediSource Lexicon