acetaminophen 250 MG / aspirin 250 MG / caffeine 65 MG Oral Tablet [Arthriten Inflammatory Pain]

RxCUI: 1303159
RxNorm name: acetaminophen 250 MG / aspirin 250 MG / caffeine 65 MG Oral Tablet [Arthriten Inflammatory Pain]
Display name: ARTHRITEN INFLAMMATORY PAIN (Oral Pill)
Full name: acetaminophen 250 MG / aspirin 250 MG / caffeine 65 MG Oral Tablet [Arthriten Inflammatory Pain]
Term type: SBD
Status: Active
Strength: 250-250-65 mg
Dose form: Tab
Route: Oral Pill
Updated: 2026-07-21 06:55:59

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 082012
Active start: 082012
Multiple ingredient: YES
Branded: YES

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
aspirin	250 MG / 1 EACH	aspirin	aspirin
acetaminophen	250 MG / 1 EACH	acetaminophen	acetaminophen
caffeine	65 MG / 1 EACH	caffeine	caffeine

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Oral Tablet	317541

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
aspirin	1191
acetaminophen	161
caffeine	1886

Source Vocabulary Codes#

Code type, Values, Count table
Code type	Values	Count	Category
PRESCRIBABLE	Y	1	ATTRIBUTES
RXNAV_STR	APAP 250 MG / ASA 250 MG / Caffeine 65 MG Oral Tablet [Arthriten Inflammatory Pain]	1	NAMES
RxNorm Name	acetaminophen 250 MG / aspirin 250 MG / caffeine 65 MG Oral Tablet [Arthriten Inflammatory Pain]	1	NAMES
RxNorm Synonym	2 linked values APAP 250 MG / ASA 250 MG / Caffeine 65 MG Oral Tablet [Arthriten Inflammatory Pain] Arthriten Inflammatory Pain (APAP 250 MG / ASA 250 MG / caffeine 65 MG) Oral Tablet	2	NAMES
TTY	SBD	1	ATTRIBUTES
SPL_SET_ID	c280ca89-4fb5-4050-90ee-d706a550a1ef	1	CODES
RxCUI	1303159	1	CODES
MMSL_CODE	BD3844	1	CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDC	Product NDC	Name	Labeler	Application
52389-237-28	52389-237	Arthriten acetaminophen, aspirin, caffeine	Kobayashi Healthcare International, Inc	M013

Drugs@FDA Applications#

Application, NDC, Name table
Application	NDC	Name	Marketing category	Labeler
M013	52389-237	Arthriten acetaminophen, aspirin, caffeine	OTC MONOGRAPH DRUG	Kobayashi Healthcare International, Inc

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 2 matching rows.

NDC11, Source, Active table
NDC11	Source	Active
52389023701	rxnav_ndcs	yes
52389023728	rxnav_ndcs	yes

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Arthriten Inflammatory Pain Formula	ACETAMINOPHEN, ASPIRIN, CAFFEINE	Kobayashi Healthcare International, Inc	c280ca89-4fb5-4050-90ee-d706a550a1ef	2025-04-11	Warnings	Exact identifier ndc (package): 52389-237-28 ndc (product): 52389-237 ndc11 (package): 52389023728 ndc11 (package): 52389023701 rxcui: 1303159

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 1 matching rows.

Set ID, RxNorm mappings, Terms table
Set ID	RxNorm mappings	Terms	SPL version	Label	Effective
c280ca89-4fb5-4050-90ee-d706a550a1ef	ARTHRITEN Inflammatory Pain Formula 250 MG / 250 MG / 65 MG Oral Tablet [PSN] · acetaminophen 250 MG / aspirin 250 MG / caffeine 65 MG Oral Tablet [Arthriten Inflammatory Pain] [SBD] · APAP 250 MG / ASA 250 MG / Caffeine 65 MG Oral Tablet [Arthriten Inflammatory Pain] [SY] · Arthriten Inflammatory Pain (APAP 250 MG / ASA 250 MG / caffeine 65 MG) Oral Tablet [SY]	4	13	Arthriten Inflammatory Pain Formula	20250411

Recently Linked DailyMed Labels#

Set ID, Title, Manufacturer table
Set ID	Title	Manufacturer	Effective
c280ca89-4fb5-4050-90ee-d706a550a1ef	Arthriten Inflammatory Pain Formula	Kobayashi Healthcare International, Inc \| Kobayashi America Manufacturing, LLC	20250411

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	N02BE	Anilides	ATC1-4		acetaminophen
ATC	A01AD	Other agents for local oral treatment	ATC1-4		aspirin
ATC	D11AX	Other dermatologicals	ATC1-4		caffeine
ATC	B01AC	Platelet aggregation inhibitors excl. heparin	ATC1-4		aspirin
ATC	N02BA	Salicylic acid and derivatives	ATC1-4		aspirin
ATC	N06BC	Xanthine derivatives	ATC1-4		caffeine
FDASPL	D014970	Xanthines	CHEM	has_chemical_structure	caffeine
FDASPL	N0000175739	Central Nervous System Stimulant	EPC	has_epc	caffeine
FDASPL	N0000175790	Methylxanthine	EPC	has_epc	caffeine
FDASPL	N0000175722	Nonsteroidal Anti-inflammatory Drug	EPC	has_epc	aspirin
FDASPL	N0000175578	Platelet Aggregation Inhibitor	EPC	has_epc	aspirin
FDASPL	N0000175729	Central Nervous System Stimulation	PE	has_pe	caffeine
MEDRT	D000082	Acetaminophen	CHEM	has_ingredient	acetaminophen
MEDRT	D001241	Aspirin	CHEM	has_ingredient	aspirin
MEDRT	D002110	Caffeine	CHEM	has_ingredient	caffeine
MEDRT	D001049	Apnea	DISEASE	may_treat	caffeine
MEDRT	D001172	Arthritis, Rheumatoid	DISEASE	may_treat	aspirin
MEDRT	D001778	Blood Coagulation Disorders	DISEASE	ci_with	aspirin
MEDRT	D001791	Blood Platelet Disorders	DISEASE	ci_with	aspirin
MEDRT	D002544	Cerebral Infarction	DISEASE	may_prevent	aspirin
MEDRT	D002644	Chickenpox	DISEASE	ci_with	aspirin
MEDRT	D002675	Child, Preschool	DISEASE	ci_with	aspirin
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	acetaminophen
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	aspirin
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	caffeine
MEDRT	D005221	Fatigue	DISEASE	may_treat	caffeine
MEDRT	D005334	Fever	DISEASE	may_prevent	acetaminophen
MEDRT	D005334	Fever	DISEASE	may_treat	aspirin
MEDRT	D005334	Fever	DISEASE	may_treat	acetaminophen
MEDRT	D005955	Glucosephosphate Dehydrogenase Deficiency	DISEASE	ci_with	acetaminophen
MEDRT	D006073	Gout	DISEASE	may_treat	aspirin
MEDRT	D006396	Hematemesis	DISEASE	ci_with	aspirin
MEDRT	D006474	Hemorrhagic Disorders	DISEASE	ci_with	aspirin
MEDRT	D007223	Infant	DISEASE	ci_with	aspirin
MEDRT	D007249	Inflammation	DISEASE	may_treat	aspirin
MEDRT	D002546	Ischemic Attack, Transient	DISEASE	may_prevent	aspirin
MEDRT	D008107	Liver Diseases	DISEASE	ci_with	acetaminophen
MEDRT	D008551	Melena	DISEASE	ci_with	aspirin
MEDRT	D009203	Myocardial Infarction	DISEASE	may_prevent	aspirin
MEDRT	D009298	Nasal Polyps	DISEASE	ci_with	aspirin
MEDRT	D010003	Osteoarthritis	DISEASE	may_treat	aspirin
MEDRT	D010146	Pain	DISEASE	may_treat	aspirin
MEDRT	D010146	Pain	DISEASE	may_prevent	acetaminophen
MEDRT	D010146	Pain	DISEASE	may_treat	acetaminophen
MEDRT	D010146	Pain	DISEASE	may_prevent	aspirin
MEDRT	D011225	Pre-Eclampsia	DISEASE	may_prevent	aspirin
MEDRT	D011263	Pregnancy Trimester, Third	DISEASE	ci_with	aspirin
MEDRT	D012213	Rheumatic Fever	DISEASE	may_treat	aspirin
MEDRT	N0000000160	Cyclooxygenase Inhibitors	MOA	has_moa	aspirin
MEDRT	N0000000133	Enzyme Inhibitors	MOA	has_moa	caffeine
MEDRT	N0000000108	Prostaglandin Receptor Antagonists	MOA	has_moa	acetaminophen
MEDRT	N0000008322	Bronchodilation	PE	has_pe	caffeine
MEDRT	N0000008331	Cardiovascular Activity Alteration	PE	has_pe	caffeine
MEDRT	N0000175724	Central Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000008567	Decreased Collecting Duct Water Permeability	PE	has_pe	caffeine
MEDRT	N0000008831	Decreased Platelet Activating Factor Production	PE	has_pe	aspirin
MEDRT	N0000008832	Decreased Platelet Aggregation	PE	has_pe	aspirin
MEDRT	N0000008836	Decreased Prostaglandin Production	PE	has_pe	aspirin
MEDRT	N0000008836	Decreased Prostaglandin Production	PE	has_pe	acetaminophen
MEDRT	N0000009006	Decreased Thromboxane Production	PE	has_pe	aspirin
MEDRT	N0000009072	Hypothalamic Endocrine Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000009197	Increased Central Nervous System Organized Electrical Activity	PE	has_pe	caffeine
MEDRT	N0000175725	Peripheral Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000000026	Hepatic Metabolism	PK	has_pk	aspirin
MEDRT	N0000000026	Hepatic Metabolism	PK	has_pk	acetaminophen
MEDRT	N0000000042	Renal Excretion	PK	has_pk	aspirin
MEDRT	N0000000042	Renal Excretion	PK	has_pk	acetaminophen

Group, Type, Concept table
Group	Type	Concept	Source
BN	BN	Arthriten Inflammatory Pain	rxnav_allrelated
DF	DF	Oral Tablet	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
DFG	DFG	Pill	rxnav_allrelated
GPCK	GPCK	{100 (acetaminophen 250 MG / aspirin 250 MG / caffeine 65 MG Oral Tablet) / 24 (acetaminophen 250 MG / aspirin 250 MG / diphenhydramine citrate 38 MG Oral Tablet) } Pack	rxnav_allrelated
IN	IN	acetaminophen	rxnav_allrelated
IN	IN	aspirin	rxnav_allrelated
IN	IN	caffeine	rxnav_allrelated
MIN	MIN	acetaminophen / aspirin / caffeine	rxnav_allrelated
SBD	SBD	acetaminophen 250 MG / aspirin 250 MG / caffeine 65 MG Oral Tablet [Arthriten Inflammatory Pain]	rxnav_allrelated
SBDC	SBDC	acetaminophen 250 MG / aspirin 250 MG / caffeine 65 MG [Arthriten Inflammatory Pain]	rxnav_allrelated
SBDF	SBDF	acetaminophen / aspirin / caffeine Oral Tablet [Arthriten Inflammatory Pain]	rxnav_allrelated
SBDG	SBDG	Arthriten Inflammatory Pain Oral Product	rxnav_allrelated
SBDG	SBDG	Arthriten Inflammatory Pain Pill	rxnav_allrelated
SCD	SCD	acetaminophen 250 MG / aspirin 250 MG / caffeine 65 MG Oral Tablet	rxnav_allrelated
SCDC	SCDC	acetaminophen 250 MG	rxnav_allrelated
SCDC	SCDC	aspirin 250 MG	rxnav_allrelated
SCDC	SCDC	caffeine 65 MG	rxnav_allrelated
SCDF	SCDF	acetaminophen / aspirin / caffeine Oral Tablet	rxnav_allrelated
SCDG	SCDG	acetaminophen / aspirin / caffeine Oral Product	rxnav_allrelated
SCDG	SCDG	acetaminophen / aspirin / caffeine Pill	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	250 MG / 250 MG / 65 MG
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
ATTRIBUTES	SCHEDULE	0
NAMES	Prescribable Synonym	ARTHRITEN Inflammatory Pain Formula 250 MG / 250 MG / 65 MG Oral Tablet
SOURCES	Source	Metathesaurus FDA Structured Product Labels
SOURCES	Source	Multum MediSource Lexicon