{1 (acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) / 1 (acetaminophen 650 MG / diphenhydramine hydrochloride 25 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) } Pack
- RxCUI
- 1428880
- RxNorm name
- {1 (acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) / 1 (acetaminophen 650 MG / diphenhydramine hydrochloride 25 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) } Pack
- Display name
- Acetaminophen/Dextromethorphan/diphenhydrAMINE/Phenylephrine (Pack)
- Full name
- {1 (acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) / 1 (acetaminophen 650 MG / diphenhydramine hydrochloride 25 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) } Pack
- Term type
- GPCK
- Status
- Active
- Strength
- mixed
- Dose form
- Pack
- Route
- Pack
- Updated
- 2026-08-02 18:46:27
RxNorm Status History#
- Status
- Active
- Source
- RXNORM
- Current
- YES
- Release start
- 082013
- Active start
- 082013
- Multiple ingredient
- YES
- Branded
- NO
Ingredients And Strength#
| Ingredient | Strength | Base | Basis of strength |
|---|---|---|---|
| acetaminophen | 650 MG / 1 EACH | acetaminophen | acetaminophen |
| dextromethorphan hydrobromide | 20 MG / 1 EACH | dextromethorphan | dextromethorphan hydrobromide |
| diphenhydramine hydrochloride | 25 MG / 1 EACH | diphenhydramine | diphenhydramine hydrochloride |
| phenylephrine hydrochloride | 10 MG / 1 EACH | phenylephrine | phenylephrine hydrochloride |
Dose Form Concepts#
| Dose form | RxCUI |
|---|---|
| Pack | 746839 |
Derived Ingredient Concepts#
| Ingredient | RxCUI |
|---|---|
| acetaminophen | 161 |
| dextromethorphan | 3289 |
| diphenhydramine | 3498 |
| phenylephrine | 8163 |
Source Vocabulary Codes#
FDA NDC Products And Packages#
| Package NDC | Product NDC | Name | Labeler | Application |
|---|---|---|---|---|
| 11673-542-12 | 11673-542 | daytime severe cold and cough and nighttime severe cold and cough Acetaminophen, Dextromethorphan HBr, Diphenhydramine HCl, Phenylephrine HCl | Target Corporation | part341 |
Drugs@FDA Applications#
UNII Substances#
No records found.
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| daytime severe cold and cough and nighttime severe cold and cough | ACETAMINOPHEN, DEXTROMETHORPHAN HBR, DIPHENHYDRAMINE HCL, PHENYLEPHRINE HCL | Target Corporation | 62eec235-431f-4429-b173-d4a9b45a4e36 | 2018-01-18 | Warnings | 11673-542-12 11673-542 11673054212 1428880 |
DailyMed RxNorm Mappings#
| Set ID | RxNorm string | TTY | SPL version | Label | Effective |
|---|---|---|---|---|---|
| 4e7475e2-af73-4bcb-8f75-f5528b9f9921 | 1 daytime (acetaminophen 650 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG Packets for Oral Solution) / 1 nighttime (acetaminophen 650 MG / diphenhydrAMINE HCl 25 MG / phenylephrine HCl 10 MG Packets for Oral Solution) Pack | PSN | 3 | Walgreens Daytime Nighttime Wal-Flu Severe Cold & Cough Kit | 20151208 |
| 4e7475e2-af73-4bcb-8f75-f5528b9f9921 | 1 daytime (acetaminophen 650 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG Packets for Oral Solution) / 1 nighttime (acetaminophen 650 MG / diphenhydramine HCl 25 MG / phenylephrine HCl 10 MG Packets for Oral Solution) Pack | SY | 3 | Walgreens Daytime Nighttime Wal-Flu Severe Cold & Cough Kit | 20151208 |
| 4e7475e2-af73-4bcb-8f75-f5528b9f9921 | {1 (acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) / 1 (acetaminophen 650 MG / diphenhydramine hydrochloride 25 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) } Pack | GPCK | 3 | Walgreens Daytime Nighttime Wal-Flu Severe Cold & Cough Kit | 20151208 |
| ce1b51d0-25b3-43d9-924d-293b3b5eaeb2 | 1 daytime (acetaminophen 650 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG Packets for Oral Solution) / 1 nighttime (acetaminophen 650 MG / diphenhydramine HCl 25 MG / phenylephrine HCl 10 MG Packets for Oral Solution) Pack | SY | 3 | CVS Pharmacy Daytime Nighttime Severe Cold & Cough Kit | 20130705 |
| ce1b51d0-25b3-43d9-924d-293b3b5eaeb2 | {1 (acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) / 1 (acetaminophen 650 MG / diphenhydramine hydrochloride 25 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) } Pack | GPCK | 3 | CVS Pharmacy Daytime Nighttime Severe Cold & Cough Kit | 20130705 |
| ce1b51d0-25b3-43d9-924d-293b3b5eaeb2 | 1 daytime (acetaminophen 650 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG Packets for Oral Solution) / 1 nighttime (acetaminophen 650 MG / diphenhydrAMINE HCl 25 MG / phenylephrine HCl 10 MG Packets for Oral Solution) Pack | PSN | 3 | CVS Pharmacy Daytime Nighttime Severe Cold & Cough Kit | 20130705 |
| 62eec235-431f-4429-b173-d4a9b45a4e36 | 1 daytime (acetaminophen 650 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG Packets for Oral Solution) / 1 nighttime (acetaminophen 650 MG / diphenhydrAMINE HCl 25 MG / phenylephrine HCl 10 MG Packets for Oral Solution) Pack | PSN | 1 | daytime severe cold and cough & nighttime severe cold and cough value pack | 20180118 |
| 62eec235-431f-4429-b173-d4a9b45a4e36 | {1 (acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) / 1 (acetaminophen 650 MG / diphenhydramine hydrochloride 25 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) } Pack | GPCK | 1 | daytime severe cold and cough & nighttime severe cold and cough value pack | 20180118 |
| 62eec235-431f-4429-b173-d4a9b45a4e36 | 1 daytime (acetaminophen 650 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG Packets for Oral Solution) / 1 nighttime (acetaminophen 650 MG / diphenhydramine HCl 25 MG / phenylephrine HCl 10 MG Packets for Oral Solution) Pack | SY | 1 | daytime severe cold and cough & nighttime severe cold and cough value pack | 20180118 |
DailyMed Labels#
| Set ID | Title | Manufacturer | Effective |
|---|---|---|---|
| adb2e4e6-255a-43c7-922e-5568156e5133 | Walgreen Co. Daytime Nighttime Wal-Flu® Severe Cold & Cough Drug Facts | Walgreen Company | 20190826 |
| 62eec235-431f-4429-b173-d4a9b45a4e36 | daytime severe cold and cough & nighttime severe cold and cough value pack | Target Corporation | 20180118 |
| 4e7475e2-af73-4bcb-8f75-f5528b9f9921 | Walgreens Daytime Nighttime Wal-Flu Severe Cold & Cough Kit | Walgreen Co. | 20151208 |
| ce1b51d0-25b3-43d9-924d-293b3b5eaeb2 | CVS Pharmacy Daytime Nighttime Severe Cold & Cough Kit | CVS Pharmacy | 20130705 |
Drug Classes#
| Source | Class ID | Class | Type | Relationship | Drug concept |
|---|---|---|---|---|---|
| ATC | C01CA | Adrenergic and dopaminergic agents | ATC1-4 | phenylephrine | |
| ATC | R06AA | Aminoalkyl ethers | ATC1-4 | diphenhydramine | |
| ATC | N02BE | Anilides | ATC1-4 | acetaminophen | |
| ATC | D04AA | Antihistamines for topical use | ATC1-4 | diphenhydramine | |
| ATC | R05DA | Opium alkaloids and derivatives | ATC1-4 | dextromethorphan | |
| ATC | C05AX | Other agents for treatment of hemorrhoids and anal fissures for topical use | ATC1-4 | phenylephrine | |
| ATC | R01BA | Sympathomimetics | ATC1-4 | phenylephrine | |
| ATC | S01FB | Sympathomimetics excl. antiglaucoma preparations | ATC1-4 | phenylephrine | |
| ATC | S01GA | Sympathomimetics used as decongestants | ATC1-4 | phenylephrine | |
| ATC | R01AB | Sympathomimetics, combinations excl. corticosteroids | ATC1-4 | phenylephrine | |
| ATC | R01AA | Sympathomimetics, plain | ATC1-4 | phenylephrine | |
| FDASPL | N0000186105 | alpha-1 Adrenergic Agonist | EPC | has_epc | phenylephrine |
| FDASPL | N0000175587 | Histamine-1 Receptor Antagonist | EPC | has_epc | diphenhydramine |
| FDASPL | N0000182149 | Sigma-1 Agonist | EPC | has_epc | dextromethorphan |
| FDASPL | N0000181821 | Uncompetitive N-methyl-D-aspartate Receptor Antagonist | EPC | has_epc | dextromethorphan |
| FDASPL | N0000000190 | Histamine H1 Receptor Antagonists | MOA | has_moa | diphenhydramine |
| FDASPL | N0000182147 | Sigma-1 Receptor Agonists | MOA | has_moa | dextromethorphan |
| FDASPL | N0000181819 | Uncompetitive NMDA Receptor Antagonists | MOA | has_moa | dextromethorphan |
| MEDRT | D000082 | Acetaminophen | CHEM | has_ingredient | acetaminophen |
| MEDRT | D003915 | Dextromethorphan | CHEM | has_ingredient | dextromethorphan hydrobromide |
| MEDRT | D003915 | Dextromethorphan | CHEM | has_ingredient | dextromethorphan |
| MEDRT | D004155 | Diphenhydramine | CHEM | has_ingredient | diphenhydramine |
| MEDRT | D004155 | Diphenhydramine | CHEM | has_ingredient | diphenhydramine hydrochloride |
| MEDRT | D010656 | Phenylephrine | CHEM | has_ingredient | phenylephrine |
| MEDRT | D010656 | Phenylephrine | CHEM | has_ingredient | phenylephrine hydrochloride |
| MEDRT | D013447 | Sulfites | CHEM | ci_chemclass | phenylephrine hydrochloride |
| MEDRT | D013447 | Sulfites | CHEM | ci_chemclass | phenylephrine |
| MEDRT | D001008 | Anxiety Disorders | DISEASE | may_treat | diphenhydramine |
| MEDRT | D001008 | Anxiety Disorders | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D003371 | Cough | DISEASE | may_treat | dextromethorphan hydrobromide |
| MEDRT | D003371 | Cough | DISEASE | may_treat | dextromethorphan |
| MEDRT | D003371 | Cough | DISEASE | may_prevent | dextromethorphan |
| MEDRT | D003371 | Cough | DISEASE | may_prevent | dextromethorphan hydrobromide |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | acetaminophen |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | dextromethorphan |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | diphenhydramine |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | dextromethorphan hydrobromide |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | phenylephrine |
| MEDRT | D004342 | Drug Hypersensitivity | DISEASE | ci_with | phenylephrine hydrochloride |
| MEDRT | D005334 | Fever | DISEASE | may_treat | acetaminophen |
| MEDRT | D005334 | Fever | DISEASE | may_prevent | acetaminophen |
| MEDRT | D005401 | Fissure in Ano | DISEASE | may_treat | phenylephrine |
| MEDRT | D005401 | Fissure in Ano | DISEASE | may_treat | phenylephrine hydrochloride |
| MEDRT | D005902 | Glaucoma, Open-Angle | DISEASE | may_treat | phenylephrine hydrochloride |
| MEDRT | D005902 | Glaucoma, Open-Angle | DISEASE | may_treat | phenylephrine |
| MEDRT | D005955 | Glucosephosphate Dehydrogenase Deficiency | DISEASE | ci_with | acetaminophen |
| MEDRT | D006484 | Hemorrhoids | DISEASE | may_treat | phenylephrine |
| MEDRT | D006484 | Hemorrhoids | DISEASE | may_treat | phenylephrine hydrochloride |
| MEDRT | D006973 | Hypertension | DISEASE | ci_with | phenylephrine hydrochloride |
| MEDRT | D006973 | Hypertension | DISEASE | ci_with | phenylephrine |
| MEDRT | D007022 | Hypotension | DISEASE | may_treat | phenylephrine |
| MEDRT | D007022 | Hypotension | DISEASE | may_treat | phenylephrine hydrochloride |
| MEDRT | D007231 | Infant, Newborn | DISEASE | ci_with | diphenhydramine |
| MEDRT | D007231 | Infant, Newborn | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D007234 | Infant, Premature | DISEASE | ci_with | diphenhydramine |
| MEDRT | D007234 | Infant, Premature | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D007774 | Lactation | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D007774 | Lactation | DISEASE | ci_with | diphenhydramine |
| MEDRT | D008107 | Liver Diseases | DISEASE | ci_with | acetaminophen |
| MEDRT | D009041 | Motion Sickness | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D009041 | Motion Sickness | DISEASE | may_treat | diphenhydramine |
| MEDRT | D015878 | Mydriasis | DISEASE | induces | phenylephrine |
| MEDRT | D015878 | Mydriasis | DISEASE | induces | phenylephrine hydrochloride |
| MEDRT | D009325 | Nausea | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D009325 | Nausea | DISEASE | may_treat | diphenhydramine |
| MEDRT | D010146 | Pain | DISEASE | may_prevent | acetaminophen |
| MEDRT | D010146 | Pain | DISEASE | may_treat | acetaminophen |
| MEDRT | D011538 | Pruritus Ani | DISEASE | may_treat | phenylephrine |
| MEDRT | D011538 | Pruritus Ani | DISEASE | may_treat | phenylephrine hydrochloride |
| MEDRT | D012221 | Rhinitis, Allergic, Perennial | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D012221 | Rhinitis, Allergic, Perennial | DISEASE | may_treat | diphenhydramine |
| MEDRT | D012223 | Rhinitis, Vasomotor | DISEASE | may_treat | phenylephrine hydrochloride |
| MEDRT | D012223 | Rhinitis, Vasomotor | DISEASE | may_treat | phenylephrine |
| MEDRT | D012772 | Shock, Septic | DISEASE | may_treat | phenylephrine hydrochloride |
| MEDRT | D012772 | Shock, Septic | DISEASE | may_treat | phenylephrine |
| MEDRT | D007319 | Sleep Initiation and Maintenance Disorders | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D007319 | Sleep Initiation and Maintenance Disorders | DISEASE | may_treat | diphenhydramine |
| MEDRT | D012912 | Sneezing | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D012912 | Sneezing | DISEASE | may_treat | diphenhydramine |
| MEDRT | D013224 | Status Asthmaticus | DISEASE | ci_with | diphenhydramine hydrochloride |
| MEDRT | D013224 | Status Asthmaticus | DISEASE | ci_with | diphenhydramine |
| MEDRT | D013617 | Tachycardia, Supraventricular | DISEASE | may_treat | phenylephrine hydrochloride |
| MEDRT | D013617 | Tachycardia, Supraventricular | DISEASE | may_treat | phenylephrine |
| MEDRT | D017180 | Tachycardia, Ventricular | DISEASE | ci_with | phenylephrine |
| MEDRT | D017180 | Tachycardia, Ventricular | DISEASE | ci_with | phenylephrine hydrochloride |
| MEDRT | D014581 | Urticaria | DISEASE | may_treat | diphenhydramine hydrochloride |
| MEDRT | D014581 | Urticaria | DISEASE | may_treat | diphenhydramine |
| MEDRT | N0000000209 | Adrenergic alpha-Agonists | MOA | has_moa | phenylephrine |
| MEDRT | N0000000209 | Adrenergic alpha-Agonists | MOA | has_moa | phenylephrine hydrochloride |
| MEDRT | N0000000190 | Histamine H1 Receptor Antagonists | MOA | has_moa | diphenhydramine hydrochloride |
| MEDRT | N0000000190 | Histamine H1 Receptor Antagonists | MOA | has_moa | diphenhydramine |
| MEDRT | N0000000184 | Monoamine Oxidase Inhibitors | MOA | ci_moa | dextromethorphan |
| MEDRT | N0000000184 | Monoamine Oxidase Inhibitors | MOA | ci_moa | dextromethorphan hydrobromide |
| MEDRT | N0000000108 | Prostaglandin Receptor Antagonists | MOA | has_moa | acetaminophen |
| MEDRT | N0000000109 | Serotonin Uptake Inhibitors | MOA | has_moa | dextromethorphan |
| MEDRT | N0000000109 | Serotonin Uptake Inhibitors | MOA | has_moa | dextromethorphan hydrobromide |
| MEDRT | N0000182147 | Sigma-1 Receptor Agonists | MOA | has_moa | dextromethorphan |
| MEDRT | N0000182147 | Sigma-1 Receptor Agonists | MOA | has_moa | dextromethorphan hydrobromide |
| MEDRT | N0000181819 | Uncompetitive NMDA Receptor Antagonists | MOA | has_moa | dextromethorphan hydrobromide |
| MEDRT | N0000181819 | Uncompetitive NMDA Receptor Antagonists | MOA | has_moa | dextromethorphan |
| MEDRT | N0000175724 | Central Nervous System Activity Alteration | PE | has_pe | acetaminophen |
| MEDRT | N0000008371 | Conjunctival Arterial Vasoconstriction | PE | has_pe | phenylephrine |
| MEDRT | N0000008371 | Conjunctival Arterial Vasoconstriction | PE | has_pe | phenylephrine hydrochloride |
| MEDRT | N0000008701 | Decreased Medullary Respiratory Drive | PE | has_pe | dextromethorphan hydrobromide |
| MEDRT | N0000008701 | Decreased Medullary Respiratory Drive | PE | has_pe | dextromethorphan |
| MEDRT | N0000008896 | Decreased Nasal and Sinus Secretions | PE | has_pe | phenylephrine |
| MEDRT | N0000008896 | Decreased Nasal and Sinus Secretions | PE | has_pe | phenylephrine hydrochloride |
| MEDRT | N0000008836 | Decreased Prostaglandin Production | PE | has_pe | acetaminophen |
| MEDRT | N0000009072 | Hypothalamic Endocrine Activity Alteration | PE | has_pe | acetaminophen |
| MEDRT | N0000175725 | Peripheral Nervous System Activity Alteration | PE | has_pe | acetaminophen |
| MEDRT | N0000000026 | Hepatic Metabolism | PK | has_pk | acetaminophen |
| MEDRT | N0000000042 | Renal Excretion | PK | has_pk | acetaminophen |
Properties#
| Category | Property | Value |
|---|---|---|
| ATTRIBUTES | GENERAL_CARDINALITY | MULTI |
| ATTRIBUTES | HUMAN_DRUG | US |
| ATTRIBUTES | PRESCRIBABLE | Y |
| ATTRIBUTES | TTY | GPCK |
| CODES | RxCUI | 1428880 |
| CODES | SPL_SET_ID | 62eec235-431f-4429-b173-d4a9b45a4e36 |
| NAMES | Prescribable Synonym | 1 daytime (acetaminophen 650 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG Packets for Oral Solution) / 1 nighttime (acetaminophen 650 MG / diphenhydrAMINE HCl 25 MG / phenylephrine HCl 10 MG Packets for Oral Solution) Pack |
| NAMES | RXNAV_STR | {1 (acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) / 1 (acetaminophen 650 MG / diphenhydrAMINE hydrochloride 25 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) } Pack |
| NAMES | RxNorm Name | {1 (acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) / 1 (acetaminophen 650 MG / diphenhydramine hydrochloride 25 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) } Pack |
| NAMES | RxNorm Synonym | 1 daytime (acetaminophen 650 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG Packets for Oral Solution) / 1 nighttime (acetaminophen 650 MG / diphenhydramine HCl 25 MG / phenylephrine HCl 10 MG Packets for Oral Solution) Pack |
| NAMES | Tallman Synonym | {1 (acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) / 1 (acetaminophen 650 MG / diphenhydrAMINE hydrochloride 25 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) } Pack |
| NAMES | Tallman Synonym | 1 daytime (acetaminophen 650 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG Packets for Oral Solution) / 1 nighttime (acetaminophen 650 MG / diphenhydrAMINE HCl 25 MG / phenylephrine HCl 10 MG Packets for Oral Solution) Pack |
| SOURCES | Source | Gold Standard Alchemy |
| SOURCES | Source | Metathesaurus FDA Structured Product Labels |
| SOURCES | Source | National Drug Data File Plus Source Vocabulary |