dextromethorphan hydrobromide 4 MG/ML / phenylephrine hydrochloride 2 MG/ML / triprolidine hydrochloride 0.5 MG/ML Oral Solution

RxCUI: 1492052
RxNorm name: dextromethorphan hydrobromide 4 MG/ML / phenylephrine hydrochloride 2 MG/ML / triprolidine hydrochloride 0.5 MG/ML Oral Solution
Display name: Dextromethorphan/Phenylephrine/Triprolidine (Oral Liquid)
Full name: dextromethorphan hydrobromide 4 MG/ML / phenylephrine hydrochloride 2 MG/ML / triprolidine hydrochloride 0.5 MG/ML Oral Solution
Term type: SCD
Status: Active
Strength: 20-10-2.5 mg/5ml
Dose form: Sol
Route: Oral Liquid
Updated: 2026-08-26 21:39:30

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 042014
Active start: 042014
Multiple ingredient: YES
Branded: NO

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
triprolidine hydrochloride	0.5 MG / 1 ML	triprolidine	triprolidine hydrochloride
dextromethorphan hydrobromide	4 MG / 1 ML	dextromethorphan	dextromethorphan hydrobromide
phenylephrine hydrochloride	2 MG / 1 ML	phenylephrine	phenylephrine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Oral Solution	316968

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
triprolidine	10849
dextromethorphan	3289
phenylephrine	8163

Source Vocabulary Codes#

Code type, Values, Count table
Code type	Values	Count	Category
PRESCRIBABLE	Y	1	ATTRIBUTES
RXNAV_STR	dextromethorphan hydrobromide 4 MG/ML / phenylephrine hydrochloride 2 MG/ML / triprolidine hydrochloride 0.5 MG/ML Oral Solution	1	NAMES
RxNorm Name	dextromethorphan hydrobromide 4 MG/ML / phenylephrine hydrochloride 2 MG/ML / triprolidine hydrochloride 0.5 MG/ML Oral Solution	1	NAMES
RxNorm Synonym	dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG / triprolidine hydrochloride 2.5 MG per 5 ML Oral Solution	1	NAMES
TTY	SCD	1	ATTRIBUTES
SPL_SET_ID	836d062c-29f0-4fd7-b65c-771a3bbd52c4	1	CODES
RxCUI	1492052	1	CODES
MMSL_CODE	2 linked values BD30653 CD30653	2	CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDC	Product NDC	Name	Labeler	Application
28595-804-16	28595-804	HISTEX-DM DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE HYDROCHLORIDE, and TRIPROLIDINE HYDROCHLORIDE	Allegis Pharmaceuticals, LLC	M012

Drugs@FDA Applications#

Application, NDC, Name table
Application	NDC	Name	Marketing category	Labeler
M012	28595-804	HISTEX-DM DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE HYDROCHLORIDE, and TRIPROLIDINE HYDROCHLORIDE	OTC MONOGRAPH DRUG	Allegis Pharmaceuticals, LLC

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 3 matching rows.

NDC11, Source, Active table
NDC11	Source	Active
28595080416	rxnav_ndcs	yes
70868070416	rxnav_ndcs	yes
70868074016	rxnav_ndcs	yes

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
HISTEX-DM	DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE HYDROCHLORIDE, AND TRIPROLIDINE HYDROCHLORIDE	Allegis Pharmaceuticals, LLC	836d062c-29f0-4fd7-b65c-771a3bbd52c4	2024-01-08	Warnings	Exact identifier ndc (package): 28595-804-16 ndc (product): 28595-804 ndc11 (package): 28595080416 rxcui: 1492052

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 2 matching rows.

Set ID, RxNorm mappings, Terms table
Set ID	RxNorm mappings	Terms	SPL version	Label	Effective
836d062c-29f0-4fd7-b65c-771a3bbd52c4	dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG / triprolidine HCl 2.5 MG in 5 mL Oral Solution [PSN] · dextromethorphan hydrobromide 4 MG/ML / phenylephrine hydrochloride 2 MG/ML / triprolidine hydrochloride 0.5 MG/ML Oral Solution [SCD] · dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG / triprolidine hydrochloride 2.5 MG per 5 ML Oral Solution [SY]	3	4	HISTEX™-DM Syrup	20240108
c86e012b-17d0-4ffd-b815-9c07771bfaf1	dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG / triprolidine HCl 2.5 MG in 5 mL Oral Solution [PSN] · dextromethorphan hydrobromide 4 MG/ML / phenylephrine hydrochloride 2 MG/ML / triprolidine hydrochloride 0.5 MG/ML Oral Solution [SCD] · dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG / triprolidine hydrochloride 2.5 MG per 5 ML Oral Solution [SY]	3	3	Miclara DM	20220126

Recently Linked DailyMed Labels#

Set ID, Title, Manufacturer table
Set ID	Title	Manufacturer	Effective
836d062c-29f0-4fd7-b65c-771a3bbd52c4	HISTEX™-DM Syrup	Allegis Pharmaceuticals, LLC	20240108
c86e012b-17d0-4ffd-b815-9c07771bfaf1	Miclara DM	Key Therapeutics \| TG United	20220126
37388ab0-27c7-47de-8bdd-1a2d164047d7	Dr Manzanilla DM Syrup	Key Therapeutics	20190811

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	C01CA	Adrenergic and dopaminergic agents	ATC1-4		phenylephrine
ATC	R05DA	Opium alkaloids and derivatives	ATC1-4		dextromethorphan
ATC	C05AX	Other agents for treatment of hemorrhoids and anal fissures for topical use	ATC1-4		phenylephrine
ATC	R06AX	Other antihistamines for systemic use	ATC1-4		triprolidine
ATC	R01BA	Sympathomimetics	ATC1-4		phenylephrine
ATC	S01FB	Sympathomimetics excl. antiglaucoma preparations	ATC1-4		phenylephrine
ATC	S01GA	Sympathomimetics used as decongestants	ATC1-4		phenylephrine
ATC	R01AB	Sympathomimetics, combinations excl. corticosteroids	ATC1-4		phenylephrine
ATC	R01AA	Sympathomimetics, plain	ATC1-4		phenylephrine
FDASPL	N0000186105	alpha-1 Adrenergic Agonist	EPC	has_epc	phenylephrine
FDASPL	N0000182149	Sigma-1 Agonist	EPC	has_epc	dextromethorphan
FDASPL	N0000181821	Uncompetitive N-methyl-D-aspartate Receptor Antagonist	EPC	has_epc	dextromethorphan
FDASPL	N0000182147	Sigma-1 Receptor Agonists	MOA	has_moa	dextromethorphan
FDASPL	N0000181819	Uncompetitive NMDA Receptor Antagonists	MOA	has_moa	dextromethorphan
MEDRT	D003915	Dextromethorphan	CHEM	has_ingredient	dextromethorphan hydrobromide
MEDRT	D003915	Dextromethorphan	CHEM	has_ingredient	dextromethorphan
MEDRT	D010656	Phenylephrine	CHEM	has_ingredient	phenylephrine hydrochloride
MEDRT	D010656	Phenylephrine	CHEM	has_ingredient	phenylephrine
MEDRT	D013447	Sulfites	CHEM	ci_chemclass	phenylephrine
MEDRT	D013447	Sulfites	CHEM	ci_chemclass	phenylephrine hydrochloride
MEDRT	D014311	Triprolidine	CHEM	has_ingredient	triprolidine hydrochloride
MEDRT	D014311	Triprolidine	CHEM	has_ingredient	triprolidine
MEDRT	D003233	Conjunctivitis, Allergic	DISEASE	may_treat	triprolidine hydrochloride
MEDRT	D003233	Conjunctivitis, Allergic	DISEASE	may_treat	triprolidine
MEDRT	D003327	Coronary Disease	DISEASE	ci_with	triprolidine
MEDRT	D003327	Coronary Disease	DISEASE	ci_with	triprolidine hydrochloride
MEDRT	D003371	Cough	DISEASE	may_treat	dextromethorphan hydrobromide
MEDRT	D003371	Cough	DISEASE	may_prevent	dextromethorphan
MEDRT	D003371	Cough	DISEASE	may_treat	dextromethorphan
MEDRT	D003371	Cough	DISEASE	may_prevent	dextromethorphan hydrobromide
MEDRT	D003876	Dermatitis, Atopic	DISEASE	may_treat	triprolidine hydrochloride
MEDRT	D003876	Dermatitis, Atopic	DISEASE	may_treat	triprolidine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	dextromethorphan
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	dextromethorphan hydrobromide
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	triprolidine hydrochloride
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	phenylephrine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	triprolidine
MEDRT	D005401	Fissure in Ano	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D005401	Fissure in Ano	DISEASE	may_treat	phenylephrine
MEDRT	D005902	Glaucoma, Open-Angle	DISEASE	may_treat	phenylephrine
MEDRT	D005902	Glaucoma, Open-Angle	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D006484	Hemorrhoids	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D006484	Hemorrhoids	DISEASE	may_treat	phenylephrine
MEDRT	D006973	Hypertension	DISEASE	ci_with	phenylephrine
MEDRT	D006973	Hypertension	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D007022	Hypotension	DISEASE	may_treat	phenylephrine
MEDRT	D007022	Hypotension	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D015878	Mydriasis	DISEASE	induces	phenylephrine hydrochloride
MEDRT	D015878	Mydriasis	DISEASE	induces	phenylephrine
MEDRT	D011538	Pruritus Ani	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D011538	Pruritus Ani	DISEASE	may_treat	phenylephrine
MEDRT	D012220	Rhinitis	DISEASE	may_treat	triprolidine
MEDRT	D012220	Rhinitis	DISEASE	may_treat	triprolidine hydrochloride
MEDRT	D012223	Rhinitis, Vasomotor	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D012223	Rhinitis, Vasomotor	DISEASE	may_treat	phenylephrine
MEDRT	D012772	Shock, Septic	DISEASE	may_treat	phenylephrine
MEDRT	D012772	Shock, Septic	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D013617	Tachycardia, Supraventricular	DISEASE	may_treat	phenylephrine
MEDRT	D013617	Tachycardia, Supraventricular	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	ci_with	phenylephrine
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	phenylephrine
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	phenylephrine hydrochloride
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	triprolidine hydrochloride
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	triprolidine
MEDRT	N0000000184	Monoamine Oxidase Inhibitors	MOA	ci_moa	dextromethorphan hydrobromide
MEDRT	N0000000184	Monoamine Oxidase Inhibitors	MOA	ci_moa	triprolidine
MEDRT	N0000000184	Monoamine Oxidase Inhibitors	MOA	ci_moa	triprolidine hydrochloride
MEDRT	N0000000184	Monoamine Oxidase Inhibitors	MOA	ci_moa	dextromethorphan
MEDRT	N0000000109	Serotonin Uptake Inhibitors	MOA	has_moa	dextromethorphan hydrobromide
MEDRT	N0000000109	Serotonin Uptake Inhibitors	MOA	has_moa	dextromethorphan
MEDRT	N0000182147	Sigma-1 Receptor Agonists	MOA	has_moa	dextromethorphan
MEDRT	N0000182147	Sigma-1 Receptor Agonists	MOA	has_moa	dextromethorphan hydrobromide
MEDRT	N0000181819	Uncompetitive NMDA Receptor Antagonists	MOA	has_moa	dextromethorphan
MEDRT	N0000181819	Uncompetitive NMDA Receptor Antagonists	MOA	has_moa	dextromethorphan hydrobromide
MEDRT	N0000008371	Conjunctival Arterial Vasoconstriction	PE	has_pe	phenylephrine
MEDRT	N0000008371	Conjunctival Arterial Vasoconstriction	PE	has_pe	phenylephrine hydrochloride
MEDRT	N0000008657	Decreased Histamine Activity	PE	has_pe	triprolidine
MEDRT	N0000008657	Decreased Histamine Activity	PE	has_pe	triprolidine hydrochloride
MEDRT	N0000008701	Decreased Medullary Respiratory Drive	PE	has_pe	dextromethorphan
MEDRT	N0000008701	Decreased Medullary Respiratory Drive	PE	has_pe	dextromethorphan hydrobromide
MEDRT	N0000008896	Decreased Nasal and Sinus Secretions	PE	has_pe	phenylephrine
MEDRT	N0000008896	Decreased Nasal and Sinus Secretions	PE	has_pe	phenylephrine hydrochloride

Group, Type, Concept table
Group	Type	Concept	Source
DF	DF	Oral Solution	rxnav_allrelated
DFG	DFG	Oral Liquid Product	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
IN	IN	dextromethorphan	rxnav_allrelated
IN	IN	phenylephrine	rxnav_allrelated
IN	IN	triprolidine	rxnav_allrelated
MIN	MIN	dextromethorphan / phenylephrine / triprolidine	rxnav_allrelated
PIN	PIN	dextromethorphan hydrobromide	rxnav_allrelated
PIN	PIN	phenylephrine hydrochloride	rxnav_allrelated
PIN	PIN	triprolidine hydrochloride	rxnav_allrelated
SCD	SCD	dextromethorphan hydrobromide 4 MG/ML / phenylephrine hydrochloride 2 MG/ML / triprolidine hydrochloride 0.5 MG/ML Oral Solution	rxnav_allrelated
SCDC	SCDC	dextromethorphan hydrobromide 4 MG/ML	rxnav_allrelated
SCDC	SCDC	phenylephrine hydrochloride 2 MG/ML	rxnav_allrelated
SCDC	SCDC	triprolidine hydrochloride 0.5 MG/ML	rxnav_allrelated
SCDF	SCDF	dextromethorphan / phenylephrine / triprolidine Oral Solution	rxnav_allrelated
SCDFP	SCDFP	dextromethorphan hydrobromide / phenylephrine hydrochloride / triprolidine hydrochloride Oral Solution	rxnav_allrelated
SCDG	SCDG	dextromethorphan / phenylephrine / triprolidine Oral Liquid Product	rxnav_allrelated
SCDG	SCDG	dextromethorphan / phenylephrine / triprolidine Oral Product	rxnav_allrelated
SCDGP	SCDGP	dextromethorphan hydrobromide / phenylephrine hydrochloride / triprolidine hydrochloride Oral Liquid Product	rxnav_allrelated
SCDGP	SCDGP	dextromethorphan hydrobromide / phenylephrine hydrochloride / triprolidine hydrochloride Oral Product	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	4 MG/ML / 2 MG/ML / 0.5 MG/ML
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
ATTRIBUTES	SCHEDULE	0
NAMES	Prescribable Synonym	dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG / triprolidine HCl 2.5 MG in 5 mL Oral Solution
SOURCES	Source	Gold Standard Alchemy
SOURCES	Source	Metathesaurus FDA Structured Product Labels
SOURCES	Source	Micromedex RED BOOK
SOURCES	Source	Multum MediSource Lexicon
SOURCES	Source	National Drug Data File Plus Source Vocabulary