aspirin 500 MG / citric acid 1000 MG / sodium bicarbonate 1985 MG Effervescent Oral Tablet [Alka-Seltzer]

RxCUI: 1536835
RxNorm name: aspirin 500 MG / citric acid 1000 MG / sodium bicarbonate 1985 MG Effervescent Oral Tablet [Alka-Seltzer]
Display name: ALKA-SELTZER (Effervescent)
Full name: aspirin 500 MG / citric acid 1000 MG / sodium bicarbonate 1985 MG Effervescent Oral Tablet [Alka-Seltzer]
Term type: SBD
Status: Active
Strength: 500-1,000-1,985 mg
Dose form: Tab
Route: Effervescent
Updated: 2026-09-14 22:58:32

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 062014
Active start: 062014
Multiple ingredient: YES
Branded: YES

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
aspirin	500 MG / 1 EACH	aspirin	aspirin
citric acid	1000 MG / 1 EACH	citric acid	citric acid
sodium bicarbonate	1985 MG / 1 EACH	sodium bicarbonate	sodium bicarbonate

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Effervescent Oral Tablet	1535727

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
aspirin	1191
citric acid	21183
sodium bicarbonate	36676

Source Vocabulary Codes#

Code type, Values, Count table
Code type	Values	Count	Category
PRESCRIBABLE	Y	1	ATTRIBUTES
RXNAV_STR	ASA 500 MG / Citric Acid 1000 MG / NaHCO3 1985 MG Effervescent Oral Tablet [Alka-Seltzer]	1	NAMES
RxNorm Name	aspirin 500 MG / citric acid 1000 MG / sodium bicarbonate 1985 MG Effervescent Oral Tablet [Alka-Seltzer]	1	NAMES
RxNorm Synonym	2 linked values Alka-Seltzer Extra Strength (aspirin 500 MG / citric acid 1000 MG / sodium bicarbonate 1985 MG) Effervescent Oral Tablet ASA 500 MG / Citric Acid 1000 MG / NaHCO3 1985 MG Effervescent Oral Tablet [Alka-Seltzer]	2	NAMES
TTY	SBD	1	ATTRIBUTES
RxCUI	1536835	1	CODES
MMSL_CODE	BD5710	1	CODES

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 8 matching rows.

NDC11, Source, Active table
NDC11	Source	Active
16500004404	rxnav_ndcs	yes
00280403512	rxnav_historical_indirect
00280403524	rxnav_historical_indirect
16500004402	rxnav_historical_indirect
16500044020	rxnav_historical_indirect
16500044040	rxnav_historical_indirect
65662040312	rxnav_historical_indirect
65662040324	rxnav_historical_indirect

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 0 matching rows.

No records found.

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	A09AB	Acid preparations	ATC1-4		citric acid
ATC	B05XA	Electrolyte solutions	ATC1-4		sodium bicarbonate
ATC	A01AD	Other agents for local oral treatment	ATC1-4		aspirin
ATC	B01AC	Platelet aggregation inhibitors excl. heparin	ATC1-4		aspirin
ATC	N02BA	Salicylic acid and derivatives	ATC1-4		aspirin
ATC	B05CB	Salt solutions	ATC1-4		sodium bicarbonate
FDASPL	N0000175722	Nonsteroidal Anti-inflammatory Drug	EPC	has_epc	aspirin
FDASPL	N0000175578	Platelet Aggregation Inhibitor	EPC	has_epc	aspirin
MEDRT	D001241	Aspirin	CHEM	has_ingredient	aspirin
MEDRT	D019343	Citric Acid	CHEM	has_ingredient	citric acid
MEDRT	D017693	Sodium Bicarbonate	CHEM	has_ingredient	sodium bicarbonate
MEDRT	D000141	Acidosis, Renal Tubular	DISEASE	may_treat	sodium bicarbonate
MEDRT	D000141	Acidosis, Renal Tubular	DISEASE	may_treat	citric acid
MEDRT	D000224	Addison Disease	DISEASE	ci_with	citric acid
MEDRT	D000471	Alkalosis	DISEASE	ci_with	sodium bicarbonate
MEDRT	D001002	Anuria	DISEASE	ci_with	citric acid
MEDRT	D001172	Arthritis, Rheumatoid	DISEASE	may_treat	aspirin
MEDRT	D001778	Blood Coagulation Disorders	DISEASE	ci_with	aspirin
MEDRT	D001791	Blood Platelet Disorders	DISEASE	ci_with	aspirin
MEDRT	D002544	Cerebral Infarction	DISEASE	may_prevent	aspirin
MEDRT	D002644	Chickenpox	DISEASE	ci_with	aspirin
MEDRT	D002675	Child, Preschool	DISEASE	ci_with	aspirin
MEDRT	D003681	Dehydration	DISEASE	ci_with	citric acid
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	sodium bicarbonate
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	aspirin
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	citric acid
MEDRT	D062787	Drug Overdose	DISEASE	may_treat	sodium bicarbonate
MEDRT	D064420	Drug-Related Side Effects and Adverse Reactions	DISEASE	may_prevent	sodium bicarbonate
MEDRT	D004415	Dyspepsia	DISEASE	may_treat	sodium bicarbonate
MEDRT	D004487	Edema	DISEASE	ci_with	sodium bicarbonate
MEDRT	D005334	Fever	DISEASE	may_treat	aspirin
MEDRT	D005764	Gastroesophageal Reflux	DISEASE	may_treat	sodium bicarbonate
MEDRT	D006073	Gout	DISEASE	may_treat	aspirin
MEDRT	D006323	Heart Arrest	DISEASE	may_treat	sodium bicarbonate
MEDRT	D006356	Heartburn	DISEASE	may_treat	sodium bicarbonate
MEDRT	D006396	Hematemesis	DISEASE	ci_with	aspirin
MEDRT	D006474	Hemorrhagic Disorders	DISEASE	ci_with	aspirin
MEDRT	D006947	Hyperkalemia	DISEASE	may_treat	sodium bicarbonate
MEDRT	D006947	Hyperkalemia	DISEASE	ci_with	citric acid
MEDRT	D006955	Hypernatremia	DISEASE	ci_with	sodium bicarbonate
MEDRT	D006996	Hypocalcemia	DISEASE	ci_with	sodium bicarbonate
MEDRT	D007223	Infant	DISEASE	ci_with	aspirin
MEDRT	D007249	Inflammation	DISEASE	may_treat	aspirin
MEDRT	D002546	Ischemic Attack, Transient	DISEASE	may_prevent	aspirin
MEDRT	D008551	Melena	DISEASE	ci_with	aspirin
MEDRT	D009203	Myocardial Infarction	DISEASE	may_prevent	aspirin
MEDRT	D009298	Nasal Polyps	DISEASE	ci_with	aspirin
MEDRT	D010003	Osteoarthritis	DISEASE	may_treat	aspirin
MEDRT	D010146	Pain	DISEASE	may_prevent	aspirin
MEDRT	D010146	Pain	DISEASE	may_treat	aspirin
MEDRT	D011225	Pre-Eclampsia	DISEASE	may_prevent	aspirin
MEDRT	D011263	Pregnancy Trimester, Third	DISEASE	ci_with	aspirin
MEDRT	D011654	Pulmonary Edema	DISEASE	ci_with	sodium bicarbonate
MEDRT	D051437	Renal Insufficiency	DISEASE	ci_with	citric acid
MEDRT	D012213	Rheumatic Fever	DISEASE	may_treat	aspirin
MEDRT	D014555	Urination Disorders	DISEASE	may_treat	citric acid
MEDRT	N0000000226	Acid-Base Activity	MOA	has_moa	sodium bicarbonate
MEDRT	N0000000236	Alkylating Activity	MOA	has_moa	citric acid
MEDRT	N0000000160	Cyclooxygenase Inhibitors	MOA	has_moa	aspirin
MEDRT	N0000000220	Electrolyte Activity	MOA	has_moa	sodium bicarbonate
MEDRT	N0000008831	Decreased Platelet Activating Factor Production	PE	has_pe	aspirin
MEDRT	N0000008832	Decreased Platelet Aggregation	PE	has_pe	aspirin
MEDRT	N0000008836	Decreased Prostaglandin Production	PE	has_pe	aspirin
MEDRT	N0000009006	Decreased Thromboxane Production	PE	has_pe	aspirin
MEDRT	N0000009054	Gastric Acid Alteration	PE	has_pe	sodium bicarbonate
MEDRT	N0000009549	Increased Renal HCO3- Excretion	PE	has_pe	citric acid
MEDRT	N0000009549	Increased Renal HCO3- Excretion	PE	has_pe	sodium bicarbonate
MEDRT	N0000000026	Hepatic Metabolism	PK	has_pk	aspirin
MEDRT	N0000000042	Renal Excretion	PK	has_pk	aspirin

Group, Type, Concept table
Group	Type	Concept	Source
BN	BN	Alka-Seltzer	rxnav_allrelated
DF	DF	Effervescent Oral Tablet	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
IN	IN	aspirin	rxnav_allrelated
IN	IN	citric acid	rxnav_allrelated
IN	IN	sodium bicarbonate	rxnav_allrelated
MIN	MIN	aspirin / citric acid / sodium bicarbonate	rxnav_allrelated
SBD	SBD	aspirin 500 MG / citric acid 1000 MG / sodium bicarbonate 1985 MG Effervescent Oral Tablet [Alka-Seltzer]	rxnav_allrelated
SBDC	SBDC	aspirin 500 MG / citric acid 1000 MG / sodium bicarbonate 1985 MG [Alka-Seltzer]	rxnav_allrelated
SBDF	SBDF	aspirin / citric acid / sodium bicarbonate Effervescent Oral Tablet [Alka-Seltzer]	rxnav_allrelated
SBDG	SBDG	Alka-Seltzer Oral Product	rxnav_allrelated
SCD	SCD	aspirin 500 MG / citric acid 1000 MG / sodium bicarbonate 1985 MG Effervescent Oral Tablet	rxnav_allrelated
SCDC	SCDC	aspirin 500 MG	rxnav_allrelated
SCDC	SCDC	citric acid 1000 MG	rxnav_allrelated
SCDC	SCDC	sodium bicarbonate 1985 MG	rxnav_allrelated
SCDF	SCDF	aspirin / citric acid / sodium bicarbonate Effervescent Oral Tablet	rxnav_allrelated
SCDG	SCDG	aspirin / citric acid / sodium bicarbonate Oral Product	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	500 MG / 1000 MG / 1985 MG
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
NAMES	Prescribable Synonym	Alka-Seltzer Extra Strength 500 MG / 1000 MG / 1985 MG Effervescent Oral Tablet
SOURCES	Source	Micromedex RED BOOK