benzethonium chloride 0.5 MG/ML / diphenhydramine hydrochloride 5 MG/ML / hydrocortisone 0.5 MG/ML Topical Spray

RxCUI: 1537194
RxNorm name: benzethonium chloride 0.5 MG/ML / diphenhydramine hydrochloride 5 MG/ML / hydrocortisone 0.5 MG/ML Topical Spray
Term type: SCD
Status: Active
Updated: 2026-09-25 04:22:14

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 062014
Active start: 062014
Multiple ingredient: YES
Branded: NO

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
benzethonium chloride	0.5 MG / 1 ML	benzethonium	benzethonium chloride
diphenhydramine hydrochloride	5 MG / 1 ML	diphenhydramine	diphenhydramine hydrochloride
hydrocortisone	0.5 MG / 1 ML	hydrocortisone	hydrocortisone

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Topical Spray	346165

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
benzethonium	1390
diphenhydramine	3498
hydrocortisone	5492

Source Vocabulary Codes#

Code type, Values, Count table
Code type	Values	Count	Category
RXNAV_STR	benzethonium chloride 0.5 MG/ML / diphenhydrAMINE hydrochloride 5 MG/ML / hydrocortisone 0.5 MG/ML Topical Spray	1	NAMES
RxNorm Name	benzethonium chloride 0.5 MG/ML / diphenhydramine hydrochloride 5 MG/ML / hydrocortisone 0.5 MG/ML Topical Spray	1	NAMES
RxNorm Synonym	benzethonium Cl 0.05 % / diphenhydramine HCl 0.5 % / hydrocortisone 0.05 % Topical Spray	1	NAMES
TTY	SCD	1	ATTRIBUTES
SPL_SET_ID	14915788-8e18-4277-adb8-82b79faaabf0	1	CODES
RxCUI	1537194	1	CODES

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 1 matching rows.

NDC11, Source, Active table
NDC11	Source	Active
43655000201	rxnav_ndcs	yes

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 1 matching rows.

Set ID, RxNorm mappings, Terms table
Set ID	RxNorm mappings	Terms	SPL version	Label	Effective
14915788-8e18-4277-adb8-82b79faaabf0	diphenhydrAMINE HCl 0.5 % / hydrocortisone 0.05 % / benzethonium Cl 0.05 % Topical Spray [PSN] · benzethonium chloride 0.5 MG/ML / diphenhydramine hydrochloride 5 MG/ML / hydrocortisone 0.5 MG/ML Topical Spray [SCD] · benzethonium Cl 0.05 % / diphenhydramine HCl 0.5 % / hydrocortisone 0.05 % Topical Spray [SY]	3	2	GNC Pets Hot Spot Spray (Premium Formula)	20181105

Recently Linked DailyMed Labels#

Set ID, Title, Manufacturer table
Set ID	Title	Manufacturer	Effective
14915788-8e18-4277-adb8-82b79faaabf0	GNC Pets Hot Spot Spray (Premium Formula)	General Nutrition Corporation \| Marianna Industries, Inc	20181105

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	R06AA	Aminoalkyl ethers	ATC1-4		diphenhydramine
ATC	D04AA	Antihistamines for topical use	ATC1-4		diphenhydramine
ATC	R02AA	Antiseptics	ATC1-4		benzethonium
ATC	S02BA	Corticosteroids	ATC1-4		hydrocortisone
ATC	C05AA	Corticosteroids	ATC1-4		hydrocortisone
ATC	A07EA	Corticosteroids acting locally	ATC1-4		hydrocortisone
ATC	A01AC	Corticosteroids for local oral treatment	ATC1-4		hydrocortisone
ATC	S01BA	Corticosteroids, plain	ATC1-4		hydrocortisone
ATC	D07AA	Corticosteroids, weak (group I)	ATC1-4		hydrocortisone
ATC	D07XA	Corticosteroids, weak, other combinations	ATC1-4		hydrocortisone
ATC	S01CB	Corticosteroids/antiinfectives/mydriatics in combination	ATC1-4		hydrocortisone
ATC	H02AB	Glucocorticoids	ATC1-4		hydrocortisone
ATC	D08AJ	Quaternary ammonium compounds	ATC1-4		benzethonium chloride
FDASPL	N0000175576	Corticosteroid	EPC	has_epc	hydrocortisone
FDASPL	N0000175587	Histamine-1 Receptor Antagonist	EPC	has_epc	diphenhydramine
FDASPL	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	diphenhydramine
MEDRT	D001558	Benzethonium	CHEM	has_ingredient	benzethonium chloride
MEDRT	D001558	Benzethonium	CHEM	has_ingredient	benzethonium
MEDRT	D004155	Diphenhydramine	CHEM	has_ingredient	diphenhydramine hydrochloride
MEDRT	D004155	Diphenhydramine	CHEM	has_ingredient	diphenhydramine
MEDRT	D006854	Hydrocortisone	CHEM	has_ingredient	hydrocortisone
MEDRT	D000312	Adrenal Hyperplasia, Congenital	DISEASE	may_treat	hydrocortisone
MEDRT	D000309	Adrenal Insufficiency	DISEASE	may_treat	hydrocortisone
MEDRT	D001008	Anxiety Disorders	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D001008	Anxiety Disorders	DISEASE	may_treat	diphenhydramine
MEDRT	D003093	Colitis, Ulcerative	DISEASE	may_treat	hydrocortisone
MEDRT	D003877	Dermatitis, Contact	DISEASE	may_treat	hydrocortisone
MEDRT	D003881	Dermatomycoses	DISEASE	ci_with	hydrocortisone
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	diphenhydramine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	hydrocortisone
MEDRT	D005148	Facial Dermatoses	DISEASE	may_treat	hydrocortisone
MEDRT	D005533	Foot Dermatoses	DISEASE	may_treat	hydrocortisone
MEDRT	D006229	Hand Dermatoses	DISEASE	may_treat	hydrocortisone
MEDRT	D006484	Hemorrhoids	DISEASE	may_treat	hydrocortisone
MEDRT	D007231	Infant, Newborn	DISEASE	ci_with	diphenhydramine
MEDRT	D007231	Infant, Newborn	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D007234	Infant, Premature	DISEASE	ci_with	diphenhydramine
MEDRT	D007234	Infant, Premature	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D007249	Inflammation	DISEASE	may_treat	hydrocortisone
MEDRT	D007774	Lactation	DISEASE	ci_with	diphenhydramine
MEDRT	D007774	Lactation	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D007868	Leg Dermatoses	DISEASE	may_treat	hydrocortisone
MEDRT	D009041	Motion Sickness	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D009041	Motion Sickness	DISEASE	may_treat	diphenhydramine
MEDRT	D009325	Nausea	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D009325	Nausea	DISEASE	may_treat	diphenhydramine
MEDRT	D011538	Pruritus Ani	DISEASE	may_treat	hydrocortisone
MEDRT	D012216	Rheumatic Diseases	DISEASE	may_treat	hydrocortisone
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	diphenhydramine
MEDRT	D012536	Scalp Dermatoses	DISEASE	may_treat	hydrocortisone
MEDRT	D012769	Shock	DISEASE	may_treat	hydrocortisone
MEDRT	D012876	Skin Diseases, Parasitic	DISEASE	ci_with	hydrocortisone
MEDRT	D017193	Skin Diseases, Viral	DISEASE	ci_with	hydrocortisone
MEDRT	D007319	Sleep Initiation and Maintenance Disorders	DISEASE	may_treat	diphenhydramine
MEDRT	D007319	Sleep Initiation and Maintenance Disorders	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D012912	Sneezing	DISEASE	may_treat	diphenhydramine
MEDRT	D012912	Sneezing	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D013224	Status Asthmaticus	DISEASE	may_treat	hydrocortisone
MEDRT	D013224	Status Asthmaticus	DISEASE	ci_with	diphenhydramine
MEDRT	D013224	Status Asthmaticus	DISEASE	ci_with	diphenhydramine hydrochloride
MEDRT	D014382	Tuberculosis, Cutaneous	DISEASE	ci_with	hydrocortisone
MEDRT	D014581	Urticaria	DISEASE	may_treat	diphenhydramine hydrochloride
MEDRT	D014581	Urticaria	DISEASE	may_treat	diphenhydramine
MEDRT	N0000000159	Glucocorticoid Receptor Agonists	MOA	has_moa	hydrocortisone
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	diphenhydramine hydrochloride
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	diphenhydramine
MEDRT	N0000000134	Lipoxygenase Inhibitors	MOA	has_moa	hydrocortisone
MEDRT	N0000008327	Carbohydrate Metabolism Alteration	PE	has_pe	hydrocortisone
MEDRT	N0000010253	Decreased Capillary Permeability	PE	has_pe	hydrocortisone
MEDRT	N0000010248	Decreased Fibroblast Migration	PE	has_pe	hydrocortisone
MEDRT	N0000008645	Decreased Glucocorticoid Secretion	PE	has_pe	hydrocortisone
MEDRT	N0000008681	Decreased Leukotriene Activity	PE	has_pe	hydrocortisone
MEDRT	N0000008700	Decreased Lysosomal Function	PE	has_pe	hydrocortisone
MEDRT	N0000010246	Decreased Polymorphonuclear Leukocyte Migration	PE	has_pe	hydrocortisone
MEDRT	N0000008834	Decreased Prostaglandin Activity	PE	has_pe	hydrocortisone
MEDRT	N0000008841	Decreased Protein Synthesis	PE	has_pe	hydrocortisone
MEDRT	N0000009004	Decreased Thromboxane Activity	PE	has_pe	hydrocortisone
MEDRT	N0000009739	Lipid Metabolism Alteration	PE	has_pe	hydrocortisone

Group, Type, Concept table
Group	Type	Concept	Source
DF	DF	Topical Spray	rxnav_allrelated
DFG	DFG	Topical Product	rxnav_allrelated
IN	IN	benzethonium	rxnav_allrelated
IN	IN	diphenhydramine	rxnav_allrelated
IN	IN	hydrocortisone	rxnav_allrelated
MIN	MIN	benzethonium / diphenhydramine / hydrocortisone	rxnav_allrelated
PIN	PIN	benzethonium chloride	rxnav_allrelated
PIN	PIN	diphenhydramine hydrochloride	rxnav_allrelated
SCD	SCD	benzethonium chloride 0.5 MG/ML / diphenhydramine hydrochloride 5 MG/ML / hydrocortisone 0.5 MG/ML Topical Spray	rxnav_allrelated
SCDC	SCDC	benzethonium chloride 0.5 MG/ML	rxnav_allrelated
SCDC	SCDC	diphenhydramine hydrochloride 5 MG/ML	rxnav_allrelated
SCDC	SCDC	hydrocortisone 0.5 MG/ML	rxnav_allrelated
SCDF	SCDF	benzethonium / diphenhydramine / hydrocortisone Topical Spray	rxnav_allrelated
SCDFP	SCDFP	benzethonium chloride / diphenhydramine hydrochloride / hydrocortisone Topical Spray	rxnav_allrelated
SCDG	SCDG	benzethonium / diphenhydramine / hydrocortisone Topical Product	rxnav_allrelated
SCDGP	SCDGP	benzethonium chloride / diphenhydramine hydrochloride / hydrocortisone Topical Product	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	RXNAV_VET_DRUG	US
ATTRIBUTES	VET_DRUG	US
NAMES	Prescribable Synonym	diphenhydrAMINE HCl 0.5 % / hydrocortisone 0.05 % / benzethonium Cl 0.05 % Topical Spray
NAMES	Tallman Synonym	benzethonium chloride 0.5 MG/ML / diphenhydrAMINE hydrochloride 5 MG/ML / hydrocortisone 0.5 MG/ML Topical Spray
NAMES	Tallman Synonym	benzethonium Cl 0.05 % / diphenhydrAMINE HCl 0.5 % / hydrocortisone 0.05 % Topical Spray
SOURCES	Source	Metathesaurus FDA Structured Product Labels