acetaminophen 325 MG / caffeine 65 MG Oral Tablet [Excedrin Mild Headache]

RxCUI: 1591934
RxNorm name: acetaminophen 325 MG / caffeine 65 MG Oral Tablet [Excedrin Mild Headache]
Display name: EXCEDRIN MILD HEADACHE (Oral Pill)
Full name: acetaminophen 325 MG / caffeine 65 MG Oral Tablet [Excedrin Mild Headache]
Term type: SBD
Status: Active
Strength: 325-65 mg
Dose form: Tab
Route: Oral Pill
Updated: 2026-10-17 23:57:11

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 112014
Active start: 112014
Multiple ingredient: YES
Branded: YES

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
acetaminophen	325 MG / 1 EACH	acetaminophen	acetaminophen
caffeine	65 MG / 1 EACH	caffeine	caffeine

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Oral Tablet	317541

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
acetaminophen	161
caffeine	1886

Source Vocabulary Codes#

Code type, Values, Count table
Code type	Values	Count	Category
PRESCRIBABLE	Y	1	ATTRIBUTES
RXNAV_STR	APAP 325 MG / Caffeine 65 MG Oral Tablet [Excedrin Mild Headache]	1	NAMES
RxNorm Name	acetaminophen 325 MG / caffeine 65 MG Oral Tablet [Excedrin Mild Headache]	1	NAMES
RxNorm Synonym	2 linked values APAP 325 MG / Caffeine 65 MG Oral Tablet [Excedrin Mild Headache] Excedrin Mild Headache (acetaminophen 325 MG / caffeine 65 MG) Oral Tablet	2	NAMES
TTY	SBD	1	ATTRIBUTES
RxCUI	1591934	1	CODES
MMSL_CODE	BD8089	1	CODES

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 4 matching rows.

NDC11, Source, Active table
NDC11	Source	Active
00067029530	rxnav_ndcs	yes
00067029583	rxnav_historical
00067812030	rxnav_historical
00067812083	rxnav_historical

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 0 matching rows.

No records found.

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	N02BE	Anilides	ATC1-4		acetaminophen
ATC	D11AX	Other dermatologicals	ATC1-4		caffeine
ATC	N06BC	Xanthine derivatives	ATC1-4		caffeine
FDASPL	D014970	Xanthines	CHEM	has_chemical_structure	caffeine
FDASPL	N0000175739	Central Nervous System Stimulant	EPC	has_epc	caffeine
FDASPL	N0000175790	Methylxanthine	EPC	has_epc	caffeine
FDASPL	N0000175729	Central Nervous System Stimulation	PE	has_pe	caffeine
MEDRT	D000082	Acetaminophen	CHEM	has_ingredient	acetaminophen
MEDRT	D002110	Caffeine	CHEM	has_ingredient	caffeine
MEDRT	D001049	Apnea	DISEASE	may_treat	caffeine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	caffeine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	acetaminophen
MEDRT	D005221	Fatigue	DISEASE	may_treat	caffeine
MEDRT	D005334	Fever	DISEASE	may_prevent	acetaminophen
MEDRT	D005334	Fever	DISEASE	may_treat	acetaminophen
MEDRT	D005955	Glucosephosphate Dehydrogenase Deficiency	DISEASE	ci_with	acetaminophen
MEDRT	D008107	Liver Diseases	DISEASE	ci_with	acetaminophen
MEDRT	D010146	Pain	DISEASE	may_prevent	acetaminophen
MEDRT	D010146	Pain	DISEASE	may_treat	acetaminophen
MEDRT	N0000000133	Enzyme Inhibitors	MOA	has_moa	caffeine
MEDRT	N0000000108	Prostaglandin Receptor Antagonists	MOA	has_moa	acetaminophen
MEDRT	N0000008322	Bronchodilation	PE	has_pe	caffeine
MEDRT	N0000008331	Cardiovascular Activity Alteration	PE	has_pe	caffeine
MEDRT	N0000175724	Central Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000008567	Decreased Collecting Duct Water Permeability	PE	has_pe	caffeine
MEDRT	N0000008836	Decreased Prostaglandin Production	PE	has_pe	acetaminophen
MEDRT	N0000009072	Hypothalamic Endocrine Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000009197	Increased Central Nervous System Organized Electrical Activity	PE	has_pe	caffeine
MEDRT	N0000175725	Peripheral Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000000026	Hepatic Metabolism	PK	has_pk	acetaminophen
MEDRT	N0000000042	Renal Excretion	PK	has_pk	acetaminophen

Group, Type, Concept table
Group	Type	Concept	Source
BN	BN	Excedrin Mild Headache	rxnav_allrelated
DF	DF	Oral Tablet	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
DFG	DFG	Pill	rxnav_allrelated
IN	IN	acetaminophen	rxnav_allrelated
IN	IN	caffeine	rxnav_allrelated
MIN	MIN	acetaminophen / caffeine	rxnav_allrelated
SBD	SBD	acetaminophen 325 MG / caffeine 65 MG Oral Tablet [Excedrin Mild Headache]	rxnav_allrelated
SBDC	SBDC	acetaminophen 325 MG / caffeine 65 MG [Excedrin Mild Headache]	rxnav_allrelated
SBDF	SBDF	acetaminophen / caffeine Oral Tablet [Excedrin Mild Headache]	rxnav_allrelated
SBDG	SBDG	Excedrin Mild Headache Oral Product	rxnav_allrelated
SBDG	SBDG	Excedrin Mild Headache Pill	rxnav_allrelated
SCD	SCD	acetaminophen 325 MG / caffeine 65 MG Oral Tablet	rxnav_allrelated
SCDC	SCDC	acetaminophen 325 MG	rxnav_allrelated
SCDC	SCDC	caffeine 65 MG	rxnav_allrelated
SCDF	SCDF	acetaminophen / caffeine Oral Tablet	rxnav_allrelated
SCDG	SCDG	acetaminophen / caffeine Oral Product	rxnav_allrelated
SCDG	SCDG	acetaminophen / caffeine Pill	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	325 MG / 65 MG
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
ATTRIBUTES	SCHEDULE	0
NAMES	Prescribable Synonym	EXCEDRIN MILD HEADACHE 325 MG / 65 MG Oral Tablet
SOURCES	Source	Multum MediSource Lexicon