acetaminophen 21.7 MG/ML / butalbital 3.33 MG/ML / caffeine 2.67 MG/ML Oral Solution [Vanatol]

RxCUI: 1648584
RxNorm name: acetaminophen 21.7 MG/ML / butalbital 3.33 MG/ML / caffeine 2.67 MG/ML Oral Solution [Vanatol]
Display name: VANATOL (Oral Liquid)
Full name: acetaminophen 21.7 MG/ML / butalbital 3.33 MG/ML / caffeine 2.67 MG/ML Oral Solution [Vanatol]
Term type: SBD
Status: Active
Strength: 325-50-40 mg/15ml
Dose form: Sol
Route: Oral Liquid
Updated: 2026-10-17 23:58:00

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 062015
Active start: 062015
Multiple ingredient: YES
Branded: YES

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
acetaminophen	21.7 MG / 1 ML	acetaminophen	acetaminophen
caffeine	2.67 MG / 1 ML	caffeine	caffeine
butalbital	3.33 MG / 1 ML	butalbital	butalbital

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Oral Solution	316968

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
acetaminophen	161
caffeine	1886
butalbital	19860

Source Vocabulary Codes#

Code type, Values, Count table
Code type	Values	Count	Category
PRESCRIBABLE	Y	1	ATTRIBUTES
RXNAV_STR	APAP 21.7 MG/ML / butalbital 3.33 MG/ML / Caffeine 2.67 MG/ML Oral Solution [Vanatol]	1	NAMES
RxNorm Name	acetaminophen 21.7 MG/ML / butalbital 3.33 MG/ML / caffeine 2.67 MG/ML Oral Solution [Vanatol]	1	NAMES
RxNorm Synonym	3 linked values APAP 21.7 MG/ML / butalbital 3.33 MG/ML / Caffeine 2.67 MG/ML Oral Solution [Vanatol] Vanatol LQ (acetaminophen 325 MG / butalbital 50 MG / caffeine 40 MG) per 15 ML Oral Solution Vanatol S (acetaminophen 325 MG / butalbital 50 MG / caffeine 40 MG) per 15 ML Oral Solution	3	NAMES
TTY	SBD	1	ATTRIBUTES
RxCUI	1648584	1	CODES
MMSL_CODE	BD12666	1	CODES

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 3 matching rows.

NDC11, Source, Active table
NDC11	Source	Active
58809035930	rxnav_ndcs	yes
58809082002	rxnav_historical
58809082016	rxnav_historical

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 0 matching rows.

No records found.

Recently Linked DailyMed Labels#

Set ID, Title, Manufacturer table
Set ID	Title	Manufacturer	Effective
2e1c1554-61e9-4f46-ac18-e321e01adc0c		GM Pharmaceuticals	20191104
bc990056-c75f-4b0b-87f8-4fb9bdcd533c		GM Pharmaceuticals	20191104

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	N02BE	Anilides	ATC1-4		acetaminophen
ATC	D11AX	Other dermatologicals	ATC1-4		caffeine
ATC	N06BC	Xanthine derivatives	ATC1-4		caffeine
FDASPL	D001463	Barbiturates	CHEM	has_chemical_structure	butalbital
FDASPL	D014970	Xanthines	CHEM	has_chemical_structure	caffeine
FDASPL	N0000175693	Barbiturate	EPC	has_epc	butalbital
FDASPL	N0000175739	Central Nervous System Stimulant	EPC	has_epc	caffeine
FDASPL	N0000175790	Methylxanthine	EPC	has_epc	caffeine
FDASPL	N0000175729	Central Nervous System Stimulation	PE	has_pe	caffeine
MEDRT	D000082	Acetaminophen	CHEM	has_ingredient	acetaminophen
MEDRT	D001463	Barbiturates	CHEM	has_ingredient	butalbital
MEDRT	D002110	Caffeine	CHEM	has_ingredient	caffeine
MEDRT	D001049	Apnea	DISEASE	may_treat	caffeine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	butalbital
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	acetaminophen
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	caffeine
MEDRT	D005221	Fatigue	DISEASE	may_treat	caffeine
MEDRT	D005334	Fever	DISEASE	may_prevent	acetaminophen
MEDRT	D005334	Fever	DISEASE	may_treat	acetaminophen
MEDRT	D005955	Glucosephosphate Dehydrogenase Deficiency	DISEASE	ci_with	acetaminophen
MEDRT	D006261	Headache	DISEASE	may_treat	butalbital
MEDRT	D008107	Liver Diseases	DISEASE	ci_with	acetaminophen
MEDRT	D010146	Pain	DISEASE	may_treat	acetaminophen
MEDRT	D010146	Pain	DISEASE	may_prevent	acetaminophen
MEDRT	D011164	Porphyrias	DISEASE	ci_with	butalbital
MEDRT	D011247	Pregnancy	DISEASE	ci_with	butalbital
MEDRT	N0000000133	Enzyme Inhibitors	MOA	has_moa	caffeine
MEDRT	N0000000105	Neurotransmitter Transporter Interactions	MOA	has_moa	butalbital
MEDRT	N0000000108	Prostaglandin Receptor Antagonists	MOA	has_moa	acetaminophen
MEDRT	N0000008322	Bronchodilation	PE	has_pe	caffeine
MEDRT	N0000008331	Cardiovascular Activity Alteration	PE	has_pe	caffeine
MEDRT	N0000175724	Central Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000008567	Decreased Collecting Duct Water Permeability	PE	has_pe	caffeine
MEDRT	N0000008768	Decreased Organized Electrical Activity	PE	has_pe	butalbital
MEDRT	N0000008836	Decreased Prostaglandin Production	PE	has_pe	acetaminophen
MEDRT	N0000009072	Hypothalamic Endocrine Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000009197	Increased Central Nervous System Organized Electrical Activity	PE	has_pe	caffeine
MEDRT	N0000175725	Peripheral Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000000026	Hepatic Metabolism	PK	has_pk	acetaminophen
MEDRT	N0000000042	Renal Excretion	PK	has_pk	acetaminophen

Group, Type, Concept table
Group	Type	Concept	Source
BN	BN	Vanatol	rxnav_allrelated
DF	DF	Oral Solution	rxnav_allrelated
DFG	DFG	Oral Liquid Product	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
IN	IN	acetaminophen	rxnav_allrelated
IN	IN	butalbital	rxnav_allrelated
IN	IN	caffeine	rxnav_allrelated
MIN	MIN	acetaminophen / butalbital / caffeine	rxnav_allrelated
SBD	SBD	acetaminophen 21.7 MG/ML / butalbital 3.33 MG/ML / caffeine 2.67 MG/ML Oral Solution [Vanatol]	rxnav_allrelated
SBDC	SBDC	acetaminophen 21.7 MG/ML / butalbital 3.33 MG/ML / caffeine 2.67 MG/ML [Vanatol]	rxnav_allrelated
SBDF	SBDF	acetaminophen / butalbital / caffeine Oral Solution [Vanatol]	rxnav_allrelated
SBDG	SBDG	Vanatol Oral Liquid Product	rxnav_allrelated
SBDG	SBDG	Vanatol Oral Product	rxnav_allrelated
SCD	SCD	acetaminophen 21.7 MG/ML / butalbital 3.33 MG/ML / caffeine 2.67 MG/ML Oral Solution	rxnav_allrelated
SCDC	SCDC	acetaminophen 21.7 MG/ML	rxnav_allrelated
SCDC	SCDC	butalbital 3.33 MG/ML	rxnav_allrelated
SCDC	SCDC	caffeine 2.67 MG/ML	rxnav_allrelated
SCDF	SCDF	acetaminophen / butalbital / caffeine Oral Solution	rxnav_allrelated
SCDG	SCDG	acetaminophen / butalbital / caffeine Oral Liquid Product	rxnav_allrelated
SCDG	SCDG	acetaminophen / butalbital / caffeine Oral Product	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	21.7 MG/ML / 3.33 MG/ML / 2.67 MG/ML
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
NAMES	Prescribable Synonym	Vanatol 50 MG / 325 MG / 40 MG in 15 mL Oral Solution
SOURCES	Source	Gold Standard Alchemy